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2012
Khan, Nowsheen; Leela, Vasanta; Gopalakrishna, Annavarapu
A study of craniofacial anthropometrics in Hyderabad (Deccan)and a review of literature Journal Article
In: Journal of Medical and Allied Sciences, vol. 2, iss. 2, pp. 54-57, 2012, ISSN: 2231-1696.
@article{Khan_2012,
title = {A study of craniofacial anthropometrics in Hyderabad (Deccan)and a review of literature},
author = {Nowsheen Khan and Vasanta Leela and Annavarapu Gopalakrishna},
url = {https://jmas.in/?mno=210563},
issn = {2231-1696},
year = {2012},
date = {2012-08-31},
journal = {Journal of Medical and Allied Sciences},
volume = {2},
issue = {2},
pages = {54-57},
abstract = {The development of an anthropometric craniofacial data base is a necessary multidisciplinary initiative, and on anthropometry of the South-Indian face is inadequate. The purpose of this investigation is to obtain average parameters that define the soft tissue facial profile of the investigated population in order to provide an important reference for community, security, social and medical applications. In this pilot study, the faces of 40 young adults were studied with standardized photography and measurements, and the data collated to determine averages for the Deccan region ethnic sub-set. This data-set has been compared and contrasted with others in literature.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The development of an anthropometric craniofacial data base is a necessary multidisciplinary initiative, and on anthropometry of the South-Indian face is inadequate. The purpose of this investigation is to obtain average parameters that define the soft tissue facial profile of the investigated population in order to provide an important reference for community, security, social and medical applications. In this pilot study, the faces of 40 young adults were studied with standardized photography and measurements, and the data collated to determine averages for the Deccan region ethnic sub-set. This data-set has been compared and contrasted with others in literature.
Arifuddin, Mehnaaz Sameera; Hazari, Mohammed Abdul Hannan; Reddy, Barra Ram
Blood pressure variations during different phases of menstrual cycle Journal Article
In: International Journal of Science and Nature, vol. 3, iss. 3, pp. 551-554, 2012, ISSN: 0973-3140.
@article{Arifuddin_2012,
title = {Blood pressure variations during different phases of menstrual cycle},
author = {Mehnaaz Sameera Arifuddin and Mohammed Abdul Hannan Hazari and Barra Ram Reddy},
url = {http://www.scienceandnature.org/IJSN/IJSN_Vol3(3)S2012/IJSN-VOL3(3)12-14.pdf},
issn = {0973-3140},
year = {2012},
date = {2012-08-10},
journal = {International Journal of Science and Nature},
volume = {3},
issue = {3},
pages = {551-554},
publisher = {Society For Science and Nature},
abstract = {Blood pressure (BP) is not constant throughout the day, on different days in a month and on different times of a
cyclical event like menstrual cycle. Variation in BP during different phases of menstrual cycle can also be attributed
to the effect of female sex hormones on cardiovascular function. The purpose of this study was to evaluate the
variation in BP during different phases of menstrual cycle and whether these changes can warrant an increase or
decrease in the dose of antihypertensive drugs in hypertensive women of reproductive age group. This study was
conducted on a healthy female subject with regular menstrual cycle of 28 days duration using ambulatory BP monitor
(TM-2430, A&D Co., Japan). 24-hour BP was recorded on alternate days for a period of 2 consecutive menstrual
cycles. BP data was divided into four groups: menstrual phase (days 2 and 4), proliferative phase (days 6, 8, 10 and
12), ovulatory phase (day 14) and secretory phase (days 16, 18, 20, 22, 24, 26 and 28). Though the differences were
noted between different phases of menstrual cycle, they were not statistically significant. To conclude, cardiovascular
homeostatic mechanisms are strong enough to correct the subtle BP changes brought about by the action of ovarian
hormones on the cardiovascular system.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Blood pressure (BP) is not constant throughout the day, on different days in a month and on different times of a
cyclical event like menstrual cycle. Variation in BP during different phases of menstrual cycle can also be attributed
to the effect of female sex hormones on cardiovascular function. The purpose of this study was to evaluate the
variation in BP during different phases of menstrual cycle and whether these changes can warrant an increase or
decrease in the dose of antihypertensive drugs in hypertensive women of reproductive age group. This study was
conducted on a healthy female subject with regular menstrual cycle of 28 days duration using ambulatory BP monitor
(TM-2430, A&D Co., Japan). 24-hour BP was recorded on alternate days for a period of 2 consecutive menstrual
cycles. BP data was divided into four groups: menstrual phase (days 2 and 4), proliferative phase (days 6, 8, 10 and
12), ovulatory phase (day 14) and secretory phase (days 16, 18, 20, 22, 24, 26 and 28). Though the differences were
noted between different phases of menstrual cycle, they were not statistically significant. To conclude, cardiovascular
homeostatic mechanisms are strong enough to correct the subtle BP changes brought about by the action of ovarian
hormones on the cardiovascular system.
cyclical event like menstrual cycle. Variation in BP during different phases of menstrual cycle can also be attributed
to the effect of female sex hormones on cardiovascular function. The purpose of this study was to evaluate the
variation in BP during different phases of menstrual cycle and whether these changes can warrant an increase or
decrease in the dose of antihypertensive drugs in hypertensive women of reproductive age group. This study was
conducted on a healthy female subject with regular menstrual cycle of 28 days duration using ambulatory BP monitor
(TM-2430, A&D Co., Japan). 24-hour BP was recorded on alternate days for a period of 2 consecutive menstrual
cycles. BP data was divided into four groups: menstrual phase (days 2 and 4), proliferative phase (days 6, 8, 10 and
12), ovulatory phase (day 14) and secretory phase (days 16, 18, 20, 22, 24, 26 and 28). Though the differences were
noted between different phases of menstrual cycle, they were not statistically significant. To conclude, cardiovascular
homeostatic mechanisms are strong enough to correct the subtle BP changes brought about by the action of ovarian
hormones on the cardiovascular system.
Rao, B. Narasimha; Reddy, Vontela Devender; Sahu, P. S.; Kumar, A. Veerendra; Kumar, M. Anthony David Swaroop; Yugandhar, P.; Rao, J. Muralishwar
The ABO blood group distribution and pulmonary tuberculosis Journal Article
In: Journal of Clinical and Diagnostic Research, vol. 6, iss. 6, pp. 943-946, 2012, ISSN: 0973-709X.
@article{Rao_2012,
title = {The ABO blood group distribution and pulmonary tuberculosis},
author = {B. Narasimha Rao and Vontela Devender Reddy and P. S. Sahu and A. Veerendra Kumar and M. Anthony David Swaroop Kumar and P. Yugandhar and J. Muralishwar Rao},
url = {https://www.jcdr.net/article_abstract.asp?issn=0973-709x&year=2012&volume=6&issue=6&page=943&issn=0973-709x&id=2298},
doi = {10.7860/jcdr.2012.4370.2298},
issn = {0973-709X},
year = {2012},
date = {2012-08-01},
urldate = {2012-08-01},
journal = {Journal of Clinical and Diagnostic Research},
volume = {6},
issue = {6},
pages = {943-946},
publisher = {JCDR Research and Publications (P) Limited},
abstract = {Aim: Over the years, large number of studies have examined the possible relationship between the blood group type and infection. The present study was aimed at observing the pattern of the ABO blood group distribution among the pulmonary tuberculosis patients from the Andhra region of the Andhra Pradesh state, India.
Methods: The ABO blood grouping and Rhesus typing were performed by using the standard slide agglutination reaction in 100 patients with a clinical and a radiological evidence of pulmonary tuberculosis and in 1400 healthy controls.
Results: A significant association was observed between the incidence of tuberculosis and the blood groups B and AB (P values are 0.048 and 0.03 respectively). The association between the incidence of tuberculosis and the blood groups A and O (P values are 0.249 and 0.069 respectively) was found insignificant. However, a significant association between the incidence of tuberculosis and a positive Rhesus antigen was observed in the blood group A (P value is 0.009). But there was no significant association between the incidence of tuberculosis and a positive Rhesus antigen with the blood groups B, AB and O.
Conclusion: The present study showed that there was an association between tuberculosis and the blood groups B and AB in this region of the Andhra Pradesh state.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Aim: Over the years, large number of studies have examined the possible relationship between the blood group type and infection. The present study was aimed at observing the pattern of the ABO blood group distribution among the pulmonary tuberculosis patients from the Andhra region of the Andhra Pradesh state, India.
Methods: The ABO blood grouping and Rhesus typing were performed by using the standard slide agglutination reaction in 100 patients with a clinical and a radiological evidence of pulmonary tuberculosis and in 1400 healthy controls.
Results: A significant association was observed between the incidence of tuberculosis and the blood groups B and AB (P values are 0.048 and 0.03 respectively). The association between the incidence of tuberculosis and the blood groups A and O (P values are 0.249 and 0.069 respectively) was found insignificant. However, a significant association between the incidence of tuberculosis and a positive Rhesus antigen was observed in the blood group A (P value is 0.009). But there was no significant association between the incidence of tuberculosis and a positive Rhesus antigen with the blood groups B, AB and O.
Conclusion: The present study showed that there was an association between tuberculosis and the blood groups B and AB in this region of the Andhra Pradesh state.
Methods: The ABO blood grouping and Rhesus typing were performed by using the standard slide agglutination reaction in 100 patients with a clinical and a radiological evidence of pulmonary tuberculosis and in 1400 healthy controls.
Results: A significant association was observed between the incidence of tuberculosis and the blood groups B and AB (P values are 0.048 and 0.03 respectively). The association between the incidence of tuberculosis and the blood groups A and O (P values are 0.249 and 0.069 respectively) was found insignificant. However, a significant association between the incidence of tuberculosis and a positive Rhesus antigen was observed in the blood group A (P value is 0.009). But there was no significant association between the incidence of tuberculosis and a positive Rhesus antigen with the blood groups B, AB and O.
Conclusion: The present study showed that there was an association between tuberculosis and the blood groups B and AB in this region of the Andhra Pradesh state.
Hazari, Mohammed Abdul Hannan; Khan, Reddipalli Tajuddin; Reddy, Barra Ram; Hassan, Mohammed Abrar
Cardiovascular autonomic dysfunction in type 2 diabetes mellitus and essential hypertension in a South Indian population Journal Article
In: Neurosciences (Riyadh), vol. 17, iss. 2, pp. 173-175, 2012, ISSN: 1319-6138.
@article{pmid22465897,
title = {Cardiovascular autonomic dysfunction in type 2 diabetes mellitus and essential hypertension in a South Indian population},
author = {Mohammed Abdul Hannan Hazari and Reddipalli Tajuddin Khan and Barra Ram Reddy and Mohammed Abrar Hassan},
url = {https://nsj.org.sa/content/17/2/173},
issn = {1319-6138},
year = {2012},
date = {2012-04-01},
urldate = {2012-04-01},
journal = {Neurosciences (Riyadh)},
volume = {17},
issue = {2},
pages = {173-175},
publisher = {Saudi Medical Journal},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Hasan, Ashfaq; Uzma, Nazia; Tirunagari, L. N. Swamy; Shoba, Alluri; Kumar, Bhaskarpillai Santhosh
Correlation of clinical profiles with obstructive sleep apnea and metabolic syndrome Journal Article
In: Sleep and Breathing, vol. 16, iss. 1, pp. 111-116, 2012, ISSN: 1520-9512.
@article{Hasan_2012,
title = {Correlation of clinical profiles with obstructive sleep apnea and metabolic syndrome},
author = {Ashfaq Hasan and Nazia Uzma and L. N. Swamy Tirunagari and Alluri Shoba and Bhaskarpillai Santhosh Kumar},
url = {https://link.springer.com/article/10.1007/s11325-010-0463-z},
doi = {10.1007/s11325-010-0463-z},
issn = {1520-9512},
year = {2012},
date = {2012-03-01},
urldate = {2012-03-01},
journal = {Sleep and Breathing},
volume = {16},
issue = {1},
pages = {111-116},
publisher = {Springer Science and Business Media LLC},
abstract = {Background: Obstructive sleep apnea (OSA) is a common condition being increasingly recognized and is associated with many diseases. Few data are available for Indian patients and public health hazard of the condition continues to be seriously underestimated in this country. The objective of this study was to evaluate the prevalence of obesity, hypertension, diabetes mellitus, and hyperlipidemia (HLP) in a South Indian population with proven OSA.
Methods: A retrospective analysis of data accrued in patients undergoing polysomnography (PSG) was undertaken. Two hundred thirty-four patients of either sex in the age of 54 ± 11 years who tested positive for OSA were compared with control group. An apnea-hypopnea index (AHI) of >5 in the presence of snoring and daytime somnolence was taken to define sleep apnea.
Results: The mean AHI among the study group with OSA was 31.3 ± 18.6 as compared with 1.2 ± 0.5 in the control group. The BMI among patients with OSA was 36 ± 6 as compared with 29 ± 4 in comparison group (p < 0.001). Among the patients with OSA, 31% were having HLP, 59% were diabetics, and 86% were hypertensive. Subjects with PSG-proven OSA had significant levels of day time sleepiness, lack of concentration, changes in mood, morning headache, and dry mouth. Nonrestorative sleep, awakening with choking, nocturnal dyspnea, insomnia with frequent awakenings, nocturia, and diaphoresis were observed in (>80%) patients. A significant difference in the sleep efficiency (16%), sleep onset (14%), and mean saturation (9%) was observed in the study group as compared to the control group.
Conclusions: The risk of obesity, hypertension, diabetes mellitus, and HLP in OSA syndrome patients was almost three times more than that of the comparing group.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Background: Obstructive sleep apnea (OSA) is a common condition being increasingly recognized and is associated with many diseases. Few data are available for Indian patients and public health hazard of the condition continues to be seriously underestimated in this country. The objective of this study was to evaluate the prevalence of obesity, hypertension, diabetes mellitus, and hyperlipidemia (HLP) in a South Indian population with proven OSA.
Methods: A retrospective analysis of data accrued in patients undergoing polysomnography (PSG) was undertaken. Two hundred thirty-four patients of either sex in the age of 54 ± 11 years who tested positive for OSA were compared with control group. An apnea-hypopnea index (AHI) of >5 in the presence of snoring and daytime somnolence was taken to define sleep apnea.
Results: The mean AHI among the study group with OSA was 31.3 ± 18.6 as compared with 1.2 ± 0.5 in the control group. The BMI among patients with OSA was 36 ± 6 as compared with 29 ± 4 in comparison group (p < 0.001). Among the patients with OSA, 31% were having HLP, 59% were diabetics, and 86% were hypertensive. Subjects with PSG-proven OSA had significant levels of day time sleepiness, lack of concentration, changes in mood, morning headache, and dry mouth. Nonrestorative sleep, awakening with choking, nocturnal dyspnea, insomnia with frequent awakenings, nocturia, and diaphoresis were observed in (>80%) patients. A significant difference in the sleep efficiency (16%), sleep onset (14%), and mean saturation (9%) was observed in the study group as compared to the control group.
Conclusions: The risk of obesity, hypertension, diabetes mellitus, and HLP in OSA syndrome patients was almost three times more than that of the comparing group.
Methods: A retrospective analysis of data accrued in patients undergoing polysomnography (PSG) was undertaken. Two hundred thirty-four patients of either sex in the age of 54 ± 11 years who tested positive for OSA were compared with control group. An apnea-hypopnea index (AHI) of >5 in the presence of snoring and daytime somnolence was taken to define sleep apnea.
Results: The mean AHI among the study group with OSA was 31.3 ± 18.6 as compared with 1.2 ± 0.5 in the control group. The BMI among patients with OSA was 36 ± 6 as compared with 29 ± 4 in comparison group (p < 0.001). Among the patients with OSA, 31% were having HLP, 59% were diabetics, and 86% were hypertensive. Subjects with PSG-proven OSA had significant levels of day time sleepiness, lack of concentration, changes in mood, morning headache, and dry mouth. Nonrestorative sleep, awakening with choking, nocturnal dyspnea, insomnia with frequent awakenings, nocturia, and diaphoresis were observed in (>80%) patients. A significant difference in the sleep efficiency (16%), sleep onset (14%), and mean saturation (9%) was observed in the study group as compared to the control group.
Conclusions: The risk of obesity, hypertension, diabetes mellitus, and HLP in OSA syndrome patients was almost three times more than that of the comparing group.
2011
Nasreen, Zahida; Jameel, Tahmeen; Hasan, Ashfaq; Naimath, Parveen; Sadasivudu, B.
Glutamate decarboxylase and GABA aminotransferase levels in different regions of rat brain on the onset of leptazol induced convulsions Journal Article
In: Neurochemical Research, vol. 37, iss. 1, pp. 202-204, 2011, ISSN: 0364-3190.
@article{Nasreen_2012,
title = {Glutamate decarboxylase and GABA aminotransferase levels in different regions of rat brain on the onset of leptazol induced convulsions},
author = {Zahida Nasreen and Tahmeen Jameel and Ashfaq Hasan and Parveen Naimath and B. Sadasivudu},
url = {https://link.springer.com/article/10.1007/s11064-011-0603-2},
doi = {10.1007/s11064-011-0603-2},
issn = {0364-3190},
year = {2011},
date = {2011-09-21},
urldate = {2011-09-21},
journal = {Neurochemical Research},
volume = {37},
issue = {1},
pages = {202-204},
abstract = {The activities of Glutamate decarboxylase (GAD) and Gamma aminobutyric acid (GABA) were studied in three regions of rat brain in heightened neuronal activity resulting in convulsions by Leptazol. These enzymes were studied in preconvulsive, convulsive and post convulsive phases. The activity of GAD decreases significantly in the preconvulsive phase in all the three regions of brain followed by a significant increase during the convulsive and post convulsive phase in cerebral cortex and cerebellum. The activity of GABA-T decreases maximal during the preconvulsive phase followed by convulsive phase. The activity of this enzyme tended to increase to control values when the postconvulsive phase was reached. Therefore, it is suggested that the concomitant decrease of GAD activity and GABA concentration, is probably an important factor in the onset of convulsions.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The activities of Glutamate decarboxylase (GAD) and Gamma aminobutyric acid (GABA) were studied in three regions of rat brain in heightened neuronal activity resulting in convulsions by Leptazol. These enzymes were studied in preconvulsive, convulsive and post convulsive phases. The activity of GAD decreases significantly in the preconvulsive phase in all the three regions of brain followed by a significant increase during the convulsive and post convulsive phase in cerebral cortex and cerebellum. The activity of GABA-T decreases maximal during the preconvulsive phase followed by convulsive phase. The activity of this enzyme tended to increase to control values when the postconvulsive phase was reached. Therefore, it is suggested that the concomitant decrease of GAD activity and GABA concentration, is probably an important factor in the onset of convulsions.
Uzma, Nazia; Kumar, Bhaskarpillai Santhosh; Priyadarsini, K. Indira
Hepatoprotective, immunomodulatory, and anti-inflammatory activities of selenocystine in experimental liver injury of rats Journal Article
In: Biological Trace Element Research, vol. 142, iss. 3, pp. 723-734, 2011, ISSN: 0163-4984.
@article{pmid20737246,
title = {Hepatoprotective, immunomodulatory, and anti-inflammatory activities of selenocystine in experimental liver injury of rats},
author = {Nazia Uzma and Bhaskarpillai Santhosh Kumar and K. Indira Priyadarsini},
url = {https://link.springer.com/article/10.1007/s12011-010-8807-x},
doi = {10.1007/s12011-010-8807-x},
issn = {0163-4984},
year = {2011},
date = {2011-09-01},
urldate = {2011-09-01},
journal = {Biological Trace Element Research},
volume = {142},
issue = {3},
pages = {723-734},
publisher = {Springer Science and Business Media LLC},
abstract = {The study was evaluated to investigate the efficacy of selenocystine (CysSeSeCys), a well-known organoselenium compound, on the prevention of carbon tetrachloride (CCl(4))-induced acute hepatic injury in Wistar rats. Forty healthy male Wistar rats were utilized in this study. Acute hepatotoxicity was induced by CCl(4) intoxication in rats. Serum biological analysis, oxidative stress, immune parameters, and gene expression of COX-2 and CYP2E1 were carried out. Pretreatment of CysSeSeCys prior to CCl(4) administration significantly prevented an increase in serum hepatic enzymatic activities. In addition, pretreatment of CysSeSeCys significantly prevented the formation of ROS, MDA, depletion of glutathione, and alteration of antioxidant enzyme activities in the liver of CCl(4)-intoxicated rats. This study also revealed that pretreatment with CysSeSeCys normalized the levels of interleukin 6 and10, IgG, and CD4 cell count. Pretreatment of CysSeSeCys significantly reversed COX-2 inflammatory response and the upregulation of CYP2E1 expression as well. Histopathological changes induced by CCl(4) were also significantly attenuated by CysSeSeCys pretreatment. CysSeSeCys has a potent hepatoprotective effect on CCl(4)-induced liver injury in rats through its antioxidative, immunomodulatory and anti-inflammatory activity. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The study was evaluated to investigate the efficacy of selenocystine (CysSeSeCys), a well-known organoselenium compound, on the prevention of carbon tetrachloride (CCl(4))-induced acute hepatic injury in Wistar rats. Forty healthy male Wistar rats were utilized in this study. Acute hepatotoxicity was induced by CCl(4) intoxication in rats. Serum biological analysis, oxidative stress, immune parameters, and gene expression of COX-2 and CYP2E1 were carried out. Pretreatment of CysSeSeCys prior to CCl(4) administration significantly prevented an increase in serum hepatic enzymatic activities. In addition, pretreatment of CysSeSeCys significantly prevented the formation of ROS, MDA, depletion of glutathione, and alteration of antioxidant enzyme activities in the liver of CCl(4)-intoxicated rats. This study also revealed that pretreatment with CysSeSeCys normalized the levels of interleukin 6 and10, IgG, and CD4 cell count. Pretreatment of CysSeSeCys significantly reversed COX-2 inflammatory response and the upregulation of CYP2E1 expression as well. Histopathological changes induced by CCl(4) were also significantly attenuated by CysSeSeCys pretreatment. CysSeSeCys has a potent hepatoprotective effect on CCl(4)-induced liver injury in rats through its antioxidative, immunomodulatory and anti-inflammatory activity.
Uzma, Nazia; Kumar, Bhaskarpillai Santhosh; Anees, Syyeda
Red wine ameliorates CCl4 - induced acute liver injury in rats Journal Article
In: Australian Journal of Biomedical Science, vol. 1, iss. 1, pp. 1-7, 2011, ISSN: 1838-2258.
@article{Uzma_2011,
title = {Red wine ameliorates CCl4 - induced acute liver injury in rats},
author = {Nazia Uzma and Bhaskarpillai Santhosh Kumar and Syyeda Anees},
url = {http://www.sciencej.com/ajhb/kumar_1_1_2011_1_7.pdf},
issn = {1838-2258},
year = {2011},
date = {2011-06-23},
urldate = {2011-06-23},
journal = {Australian Journal of Biomedical Science},
volume = {1},
issue = {1},
pages = {1-7},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Hasan, Ashfaq; Saxena, Amrit B.; Ahmed, Syed Mahmood; Swamy, T. L. N.
Amyotrophic lateral sclerosis presenting with orthopnea in a patient with COPD and obstructive sleep apnea Journal Article
In: Journal of Medical and Allied Sciences, vol. 1, iss. 1, pp. 46-49, 2011, ISSN: 2231-1696.
@article{Hasan_2011,
title = {Amyotrophic lateral sclerosis presenting with orthopnea in a patient with COPD and obstructive sleep apnea},
author = {Ashfaq Hasan and Amrit B. Saxena and Syed Mahmood Ahmed and T. L. N. Swamy},
url = {https://jmas.in/fulltext/154-1449470473.pdf?1698477675},
issn = {2231-1696},
year = {2011},
date = {2011-01-31},
urldate = {2011-01-31},
journal = {Journal of Medical and Allied Sciences},
volume = {1},
issue = {1},
pages = {46-49},
abstract = {Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) is a relentlessly progressive neurological disorder causing peripheral muscular weakness and resultant respiratory failure. In this article, we report a case of ALS with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) with orthopnea as initial symptoms.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) is a relentlessly progressive neurological disorder causing peripheral muscular weakness and resultant respiratory failure. In this article, we report a case of ALS with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) with orthopnea as initial symptoms.
2010
Uzma, Nazia; Kumar, Bhaskarpillai Santhosh; Hazari, Mohammed Abdul Hannan
Exposure to benzene induces oxidative stress, alters the immune response and expression of p53 in gasoline filling workers Journal Article
In: American Journal of Industrial Medicine, vol. 53, iss. 12, pp. 1264-1270, 2010, ISSN: 1097-0274.
@article{pmid20886531,
title = {Exposure to benzene induces oxidative stress, alters the immune response and expression of p53 in gasoline filling workers},
author = {Nazia Uzma and Bhaskarpillai Santhosh Kumar and Mohammed Abdul Hannan Hazari},
doi = {10.1002/ajim.20901},
issn = {1097-0274},
year = {2010},
date = {2010-12-01},
urldate = {2010-12-01},
journal = {American Journal of Industrial Medicine},
volume = {53},
issue = {12},
pages = {1264-1270},
publisher = {John Wiley & Sons},
abstract = {BACKGROUND: Chronic exposure to benzene can lead to deleterious effects on many biological systems including blood and blood-forming organs. We investigated the adverse effects of benzene among workers occupationally exposed to benzene in India.
METHODS: Four hundred twenty-eight gasoline filling workers occupationally exposed to benzene and 78 unexposed individuals were recruited for this study. Benzene concentration was determined by gas chromatography, reactive oxygen species (ROS) by dichlorofluorescin diacetate (DCFH-DA) method, malondialdehyde (MDA) by thiobarbituric acid reactive substances assay (TBARS), total superoxide dismutase (T-SOD) by RANSOD kit and glutathione (GSH) by 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) reaction, respectively. CD4, CD8, IgG were carried out by using fluorescence activated cell sorter (FACS Calibur) and mRNA expression of p53 by reverse transcriptase PCR (RT-PCR).
RESULTS: A significant increase in the concentration of benzene and its byproducts in both blood and urine were found in the workers compared with the controls. The levels of ROS and MDA were significantly elevated, and GSH and total T-SOD were decreased in the workers compared with the controls. A statistically significant decrease in the immunoglobulin levels, CD4T cells, CD4/CD8 ratio was observed in workers (vs. controls), whereas no significant difference was observed in CD8T cells. p53 gene expression was markedly higher in workers than in controls.
CONCLUSION: Occupational exposure to benzene causes oxidative stress, immune suppression and increases the expression of tumor-suppressing gene p53 in gasoline filling workers. These bio-functional markers might be useful in screening and surveillance for occupational hazard.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: Chronic exposure to benzene can lead to deleterious effects on many biological systems including blood and blood-forming organs. We investigated the adverse effects of benzene among workers occupationally exposed to benzene in India.
METHODS: Four hundred twenty-eight gasoline filling workers occupationally exposed to benzene and 78 unexposed individuals were recruited for this study. Benzene concentration was determined by gas chromatography, reactive oxygen species (ROS) by dichlorofluorescin diacetate (DCFH-DA) method, malondialdehyde (MDA) by thiobarbituric acid reactive substances assay (TBARS), total superoxide dismutase (T-SOD) by RANSOD kit and glutathione (GSH) by 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) reaction, respectively. CD4, CD8, IgG were carried out by using fluorescence activated cell sorter (FACS Calibur) and mRNA expression of p53 by reverse transcriptase PCR (RT-PCR).
RESULTS: A significant increase in the concentration of benzene and its byproducts in both blood and urine were found in the workers compared with the controls. The levels of ROS and MDA were significantly elevated, and GSH and total T-SOD were decreased in the workers compared with the controls. A statistically significant decrease in the immunoglobulin levels, CD4T cells, CD4/CD8 ratio was observed in workers (vs. controls), whereas no significant difference was observed in CD8T cells. p53 gene expression was markedly higher in workers than in controls.
CONCLUSION: Occupational exposure to benzene causes oxidative stress, immune suppression and increases the expression of tumor-suppressing gene p53 in gasoline filling workers. These bio-functional markers might be useful in screening and surveillance for occupational hazard.
METHODS: Four hundred twenty-eight gasoline filling workers occupationally exposed to benzene and 78 unexposed individuals were recruited for this study. Benzene concentration was determined by gas chromatography, reactive oxygen species (ROS) by dichlorofluorescin diacetate (DCFH-DA) method, malondialdehyde (MDA) by thiobarbituric acid reactive substances assay (TBARS), total superoxide dismutase (T-SOD) by RANSOD kit and glutathione (GSH) by 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) reaction, respectively. CD4, CD8, IgG were carried out by using fluorescence activated cell sorter (FACS Calibur) and mRNA expression of p53 by reverse transcriptase PCR (RT-PCR).
RESULTS: A significant increase in the concentration of benzene and its byproducts in both blood and urine were found in the workers compared with the controls. The levels of ROS and MDA were significantly elevated, and GSH and total T-SOD were decreased in the workers compared with the controls. A statistically significant decrease in the immunoglobulin levels, CD4T cells, CD4/CD8 ratio was observed in workers (vs. controls), whereas no significant difference was observed in CD8T cells. p53 gene expression was markedly higher in workers than in controls.
CONCLUSION: Occupational exposure to benzene causes oxidative stress, immune suppression and increases the expression of tumor-suppressing gene p53 in gasoline filling workers. These bio-functional markers might be useful in screening and surveillance for occupational hazard.
Kumar, Bhaskarpillai Santhosh; Tiwari, Santosh K.; Saikant, R.; Manoj, G.; Kunwar, Amit; Sivaram, G.; Abid, Zakia; Ahmad, Adeel; Priyadarsini, K. Indira; Khan, Aleem Ahmed
Antibacterial and ulcer healing effects of organoselenium compounds in naproxen induced and Helicobacter pylori infected Wistar rat model Journal Article
In: Journal of Trace Elements in Medicine and Biology, vol. 24, iss. 4, pp. 263-270, 2010.
@article{Kumar_2010b,
title = {Antibacterial and ulcer healing effects of organoselenium compounds in naproxen induced and Helicobacter pylori infected Wistar rat model},
author = {Bhaskarpillai Santhosh Kumar and Santosh K. Tiwari and R. Saikant and G. Manoj and Amit Kunwar and G. Sivaram and Zakia Abid and Adeel Ahmad and K. Indira Priyadarsini and Aleem Ahmed Khan},
url = {https://doi.org/10.1016%2Fj.jtemb.2010.04.003},
doi = {10.1016/j.jtemb.2010.04.003},
year = {2010},
date = {2010-10-01},
urldate = {2010-10-01},
journal = {Journal of Trace Elements in Medicine and Biology},
volume = {24},
issue = {4},
pages = {263-270},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Khatoon, Nazeema; Kumar, Bhaskarpillai Santhosh; Hazari, Mohammed Abdul Hannan
Cardiovascular autonomic neuropathy in patients with diabetes mellitus Journal Article
In: International Journal of Pharma and Biosciences, vol. 1, iss. 3, 2010, ISSN: 0975-6299.
@article{nokey,
title = {Cardiovascular autonomic neuropathy in patients with diabetes mellitus},
author = {Nazeema Khatoon and Bhaskarpillai Santhosh Kumar and Mohammed Abdul Hannan Hazari},
url = {https://www.ijpbs.net/abstract.php?article=NTI0},
issn = {0975-6299},
year = {2010},
date = {2010-09-01},
urldate = {2010-09-01},
journal = {International Journal of Pharma and Biosciences},
volume = {1},
issue = {3},
abstract = {The cardioautonomic reflexes of 82 diabetic subjects and 40 age and sex matched healthy controls were studied using blood pressure and heart rate variation in response to standing, deep breathing, isometric exercise, cold pressor test and determination of QTc interval. Among the 82 patients, 68 patients were found to have cardiac autonomic neuropathy (CAN). Results showed that diabetics had significantly impaired cardioautonomic reflexes compared to non-diabetics, which increases with the duration of diabetes. Out of 68 patients with CAN, QTc prolongation was observed in 64 patients. In conclusion the autonomic nervous system integrity is appeared to be greatly affected by diabetes mellitus and the degree of impairment was dependent on duration of the disease.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The cardioautonomic reflexes of 82 diabetic subjects and 40 age and sex matched healthy controls were studied using blood pressure and heart rate variation in response to standing, deep breathing, isometric exercise, cold pressor test and determination of QTc interval. Among the 82 patients, 68 patients were found to have cardiac autonomic neuropathy (CAN). Results showed that diabetics had significantly impaired cardioautonomic reflexes compared to non-diabetics, which increases with the duration of diabetes. Out of 68 patients with CAN, QTc prolongation was observed in 64 patients. In conclusion the autonomic nervous system integrity is appeared to be greatly affected by diabetes mellitus and the degree of impairment was dependent on duration of the disease.
Kumar, Bhaskarpillai Santhosh; Kunwar, Amit; Singh, Beena G.; Ahmad, Adeel; Priyadarsini, K. Indira
Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: An in vitro study Journal Article
In: Biological Trace Element Research, vol. 140, iss. 2, pp. 127-138, 2010.
@article{Kumar_2010c,
title = {Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: An in vitro study},
author = {Bhaskarpillai Santhosh Kumar and Amit Kunwar and Beena G. Singh and Adeel Ahmad and K. Indira Priyadarsini},
url = {https://doi.org/10.1007%2Fs12011-010-8692-3},
doi = {10.1007/s12011-010-8692-3},
year = {2010},
date = {2010-04-01},
urldate = {2010-04-01},
journal = {Biological Trace Element Research},
volume = {140},
issue = {2},
pages = {127-138},
publisher = {Springer Science and Business Media LLC},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Manoj, G.; Tiwari, Santosh K.; Sivaram, G.; Saikant, R.; Bardia, Avinash; Kumar, Bhaskarpillai Santhosh; Abid, Zakia; Habeeb, Md. Aejaz; Khan, Aleem Ahmed; Habibullah, Chitoor Mohammed
In: Reviews in Infection, vol. 1, iss. 1, pp. 31-37, 2010, ISSN: 1837-6738.
@article{Manoj_2010,
title = {Genetic variability in the repeat region of cytotoxin associated gene A of Indian Helicobacter pylori strains and its implication on various acid peptic disorders},
author = {G. Manoj and Santosh K. Tiwari and G. Sivaram and R. Saikant and Avinash Bardia and Bhaskarpillai Santhosh Kumar and Zakia Abid and Md. Aejaz Habeeb and Aleem Ahmed Khan and Chitoor Mohammed Habibullah},
url = {http://www.sciencej.com/ri/RIF_aleem_1_1_2010_31_37.pdf},
issn = {1837-6738},
year = {2010},
date = {2010-03-31},
urldate = {2010-03-31},
journal = {Reviews in Infection},
volume = {1},
issue = {1},
pages = {31-37},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Tiwari, Santosh K.; Manoj, G.; Sharma, Vishwas; Sivaram, G.; Saikant, R.; Bardia, Avinash; Sharma, Varun K.; Abid, Zakia; Khan, Aleem Ahmed; Habeeb, Md. Aejaz; Habibullah, Chitoor Mohammed; Kumar, Bhaskarpillai Santhosh; Nandan, Amrita
Relevance of Helicobacter pylori genotypes in gastric pathology and its association with plasma malondialdehyde and nitric oxide levels Journal Article
In: Inflammopharmacology, vol. 18, iss. 2, pp. 59-64, 2010.
@article{Tiwari_2010,
title = {Relevance of Helicobacter pylori genotypes in gastric pathology and its association with plasma malondialdehyde and nitric oxide levels},
author = {Santosh K. Tiwari and G. Manoj and Vishwas Sharma and G. Sivaram and R. Saikant and Avinash Bardia and Varun K. Sharma and Zakia Abid and Aleem Ahmed Khan and Md. Aejaz Habeeb and Chitoor Mohammed Habibullah and Bhaskarpillai Santhosh Kumar and Amrita Nandan},
url = {https://doi.org/10.1007%2Fs10787-010-0031-y},
doi = {10.1007/s10787-010-0031-y},
year = {2010},
date = {2010-02-01},
urldate = {2010-02-01},
journal = {Inflammopharmacology},
volume = {18},
issue = {2},
pages = {59-64},
publisher = {Springer Science and Business Media LLC},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Kumar, Bhaskarpillai Santhosh; Tiwari, Santosh K.; Manoj, G.; Kunwar, Amit; Amrita, N.; Sivaram, G.; Abid, Zakia; Ahmad, Adeel; Khan, Aleem Ahmed; Priyadarsini, K. Indira
Anti-unlcer and antimicrobial activities of sodium selenite against Helicobacter pylori: In vitro and in vivo evaluation Journal Article
In: Scandinavian Journal of Infectious Diseases, vol. 42, iss. 4, pp. 266-274, 2010.
@article{Kumar_2010,
title = {Anti-unlcer and antimicrobial activities of sodium selenite against Helicobacter pylori: In vitro and in vivo evaluation},
author = {Bhaskarpillai Santhosh Kumar and Santosh K. Tiwari and G. Manoj and Amit Kunwar and N. Amrita and G. Sivaram and Zakia Abid and Adeel Ahmad and Aleem Ahmed Khan and K. Indira Priyadarsini},
url = {https://doi.org/10.3109%2F00365540903493707},
doi = {10.3109/00365540903493707},
year = {2010},
date = {2010-01-01},
urldate = {2010-01-01},
journal = {Scandinavian Journal of Infectious Diseases},
volume = {42},
issue = {4},
pages = {266-274},
publisher = {Informa UK Limited},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2009
Kumar, Bhaskarpillai Santhosh; Kunwar, Amit; Ahmad, Adeel; Kumbhare, L. B.; Jain, V. K.; Priyadarsini, K. Indira
In-vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides Journal Article
In: Radiation and Environmental Biophysics, vol. 48, iss. 4, pp. 379-384, 2009, ISSN: 0301-634X.
@article{Kumar_2009,
title = {In-vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides},
author = {Bhaskarpillai Santhosh Kumar and Amit Kunwar and Adeel Ahmad and L. B. Kumbhare and V. K. Jain and K. Indira Priyadarsini},
url = {https://link.springer.com/article/10.1007/s00411-009-0240-1},
doi = {10.1007/s00411-009-0240-1},
issn = {0301-634X},
year = {2009},
date = {2009-09-16},
urldate = {2009-09-01},
journal = {Radiation and Environmental Biophysics},
volume = {48},
issue = {4},
pages = {379-384},
publisher = {Springer Science and Business Media LLC},
abstract = {Organoselenium compounds belonging to the class of monoselenides, such as selenomethionine (SeM) and methylselenocysteine (MSeCys) and diselenides including selenocystine (SeCys) and selenopropionic acid (SePA), were examined for their comparative radioprotective effects using in vitro models. Effects of these compounds on the inhibition of γ-radiation induced lipid peroxidation in liposomes, protein carbonylation in bovine serum albumin (BSA) and strand breaks in pBR322 plasmid DNA, assessed, respectively, by the formation of thiobarbituric acid reactive substances, formation of 2,2′-dinitrophenyl hydrazine (DNPH) carbonyl complex and horizontal gel electrophoresis, were used to compare their radioprotective ability. The IC50 values for SeCys, SePA, SeM and MSeCys for lipid peroxidation were 27 ± 1, 33 ± 2, 200 ± 8 and 163 ± 4 μM, respectively, and the values for inhibition of protein carbonylation were >200, 300 ± 6, 464 ± 8 and 436 ± 3 μM, respectively. Inhibition of DNA strand break formation was tested at 200 μM for all the compounds and SePA and SeCys exhibited a protective effect on DNA, while SeM and MSeCys did not lead to any protection. The in vitro cytotoxicity studies in normal and tumor cells revealed that MSeCys and SeM were not cytotoxic to lymphocytes and EL4 tumor cells at the concentrations employed. In contrast, SeCys was toxic, with a higher effect on tumor cells than lymphocytes. Our studies suggest that the non-toxic diselenides like SePA should be explored as protective agents against γ-irradiation induced damage.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Organoselenium compounds belonging to the class of monoselenides, such as selenomethionine (SeM) and methylselenocysteine (MSeCys) and diselenides including selenocystine (SeCys) and selenopropionic acid (SePA), were examined for their comparative radioprotective effects using in vitro models. Effects of these compounds on the inhibition of γ-radiation induced lipid peroxidation in liposomes, protein carbonylation in bovine serum albumin (BSA) and strand breaks in pBR322 plasmid DNA, assessed, respectively, by the formation of thiobarbituric acid reactive substances, formation of 2,2′-dinitrophenyl hydrazine (DNPH) carbonyl complex and horizontal gel electrophoresis, were used to compare their radioprotective ability. The IC50 values for SeCys, SePA, SeM and MSeCys for lipid peroxidation were 27 ± 1, 33 ± 2, 200 ± 8 and 163 ± 4 μM, respectively, and the values for inhibition of protein carbonylation were >200, 300 ± 6, 464 ± 8 and 436 ± 3 μM, respectively. Inhibition of DNA strand break formation was tested at 200 μM for all the compounds and SePA and SeCys exhibited a protective effect on DNA, while SeM and MSeCys did not lead to any protection. The in vitro cytotoxicity studies in normal and tumor cells revealed that MSeCys and SeM were not cytotoxic to lymphocytes and EL4 tumor cells at the concentrations employed. In contrast, SeCys was toxic, with a higher effect on tumor cells than lymphocytes. Our studies suggest that the non-toxic diselenides like SePA should be explored as protective agents against γ-irradiation induced damage.
Uzma, Nazia; Kumar, Bhaskarpillai Santhosh; Salar, B. M. Khaja Mohinuddin; Zafar, Mohammed Atheshm; Reddy, Vontela Devender
A comparative clinical survey of the prevalence of refractive errors and eye diseases in urban and rural school children Journal Article
In: Canadian Journal of Ophthalmology, vol. 44, iss. 3, pp. 328-333, 2009, ISSN: 0008-4182.
@article{Uzma_2009,
title = {A comparative clinical survey of the prevalence of refractive errors and eye diseases in urban and rural school children},
author = {Nazia Uzma and Bhaskarpillai Santhosh Kumar and B. M. Khaja Mohinuddin Salar and Mohammed Atheshm Zafar and Vontela Devender Reddy},
url = {https://www.canadianjournalofophthalmology.ca/article/S0008-4182(09)80093-8/pdf},
doi = {10.3129/i09-030},
issn = {0008-4182},
year = {2009},
date = {2009-06-30},
urldate = {2009-06-01},
journal = {Canadian Journal of Ophthalmology},
volume = {44},
issue = {3},
pages = {328-333},
publisher = {Elsevier BV},
abstract = {Objective: To assess the prevalence of refractive error and common ocular diseases in school-aged children in urban and rural populations in and around Hyderabad, India.
Design: Population-based, cross-sectional study. Participants: A total of 3314 school children, 1789 from urban areas and 1525 from rural areas.
Methods: The examination included visual acuity measurements, retinoscopy and autorefraction under cycloplegia, examination of the anterior segment and external eye, and ocular motility evaluation.
Results: In the urban group the prevalence of uncorrected presenting and best-corrected visual impairment (≤20/40 in the better eye) was 9.8%, which dropped to 7.1% with presenting vision and was further reduced to 1.1% with best-corrected visual acuity. Uncorrected visual acuity in the rural group was 6.6%, which dropped to 3.3% with presenting vision and was further reduced to 2.5% with best-corrected visual acuity. The prevalence of refractive error was greater (25.2%) in the urban than the rural group (8%). Myopia measured with autorefraction was observed in 51.4% of urban children and 16.7% in rural children. Increased literacy rate, duration of study hours, and older age of the child were found to have contributed more to the prevalence of myopia in the urban group. Hyperopia with autorefraction was found to be 3.3% in the urban and 3.1% in the rural group. Hyperopia was associated with younger age in the study group. Trachoma was the leading cause of ocular morbidity in the rural group (3.5%) compared with the urban group (0.16%). Night blindness was reported in 3.2% of children in the rural group and 0.33% in the urban group. Vitamin A deficiency, low socio-economic status, and poor personal and environmental hygienic practice were found to have a positive correlation with ocular morbidity among rural group children.
Conclusions: Provision of health education, periodic visual screening programs, and primary eye care by trained health care personnel in the elementary schools will prevent the prevalence of refractive errors and common ocular diseases in school children.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Objective: To assess the prevalence of refractive error and common ocular diseases in school-aged children in urban and rural populations in and around Hyderabad, India.
Design: Population-based, cross-sectional study. Participants: A total of 3314 school children, 1789 from urban areas and 1525 from rural areas.
Methods: The examination included visual acuity measurements, retinoscopy and autorefraction under cycloplegia, examination of the anterior segment and external eye, and ocular motility evaluation.
Results: In the urban group the prevalence of uncorrected presenting and best-corrected visual impairment (≤20/40 in the better eye) was 9.8%, which dropped to 7.1% with presenting vision and was further reduced to 1.1% with best-corrected visual acuity. Uncorrected visual acuity in the rural group was 6.6%, which dropped to 3.3% with presenting vision and was further reduced to 2.5% with best-corrected visual acuity. The prevalence of refractive error was greater (25.2%) in the urban than the rural group (8%). Myopia measured with autorefraction was observed in 51.4% of urban children and 16.7% in rural children. Increased literacy rate, duration of study hours, and older age of the child were found to have contributed more to the prevalence of myopia in the urban group. Hyperopia with autorefraction was found to be 3.3% in the urban and 3.1% in the rural group. Hyperopia was associated with younger age in the study group. Trachoma was the leading cause of ocular morbidity in the rural group (3.5%) compared with the urban group (0.16%). Night blindness was reported in 3.2% of children in the rural group and 0.33% in the urban group. Vitamin A deficiency, low socio-economic status, and poor personal and environmental hygienic practice were found to have a positive correlation with ocular morbidity among rural group children.
Conclusions: Provision of health education, periodic visual screening programs, and primary eye care by trained health care personnel in the elementary schools will prevent the prevalence of refractive errors and common ocular diseases in school children.
Design: Population-based, cross-sectional study. Participants: A total of 3314 school children, 1789 from urban areas and 1525 from rural areas.
Methods: The examination included visual acuity measurements, retinoscopy and autorefraction under cycloplegia, examination of the anterior segment and external eye, and ocular motility evaluation.
Results: In the urban group the prevalence of uncorrected presenting and best-corrected visual impairment (≤20/40 in the better eye) was 9.8%, which dropped to 7.1% with presenting vision and was further reduced to 1.1% with best-corrected visual acuity. Uncorrected visual acuity in the rural group was 6.6%, which dropped to 3.3% with presenting vision and was further reduced to 2.5% with best-corrected visual acuity. The prevalence of refractive error was greater (25.2%) in the urban than the rural group (8%). Myopia measured with autorefraction was observed in 51.4% of urban children and 16.7% in rural children. Increased literacy rate, duration of study hours, and older age of the child were found to have contributed more to the prevalence of myopia in the urban group. Hyperopia with autorefraction was found to be 3.3% in the urban and 3.1% in the rural group. Hyperopia was associated with younger age in the study group. Trachoma was the leading cause of ocular morbidity in the rural group (3.5%) compared with the urban group (0.16%). Night blindness was reported in 3.2% of children in the rural group and 0.33% in the urban group. Vitamin A deficiency, low socio-economic status, and poor personal and environmental hygienic practice were found to have a positive correlation with ocular morbidity among rural group children.
Conclusions: Provision of health education, periodic visual screening programs, and primary eye care by trained health care personnel in the elementary schools will prevent the prevalence of refractive errors and common ocular diseases in school children.
2008
Tiwari, Santosh K.; Manoj, G.; Kumar, G. Vasanth; Sivaram, G.; Hassan, Syed Ibrahim; Prabhakar, B.; Devi, U.; Jalaluddin, S.; Kumar, K.; Ahmed, S.; Abid, Zakia; Habeeb, Md. Aejaz; Khan, Aleem Ahmed; Habibullah, Chitoor Mohammed
Prognostic significance of genotyping Helicobacter pylori infection in patients in younger age groups with gastric cancer Journal Article
In: Postgraduate Medical Journal, vol. 84, iss. 990, pp. 193-197, 2008.
@article{Tiwari_2008,
title = {Prognostic significance of genotyping Helicobacter pylori infection in patients in younger age groups with gastric cancer},
author = {Santosh K. Tiwari and G. Manoj and G. Vasanth Kumar and G. Sivaram and Syed Ibrahim Hassan and B. Prabhakar and U. Devi and S. Jalaluddin and K. Kumar and S. Ahmed and Zakia Abid and Md. Aejaz Habeeb and Aleem Ahmed Khan and Chitoor Mohammed Habibullah},
url = {https://doi.org/10.1136%2Fpgmj.2007.065060},
doi = {10.1136/pgmj.2007.065060},
year = {2008},
date = {2008-04-01},
urldate = {2008-04-01},
journal = {Postgraduate Medical Journal},
volume = {84},
issue = {990},
pages = {193-197},
publisher = {Oxford University Press (OUP)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2007
Tiwari, Santosh K.; Khan, Aleem Ahmed; Manoj, G.; Ahmed, S.; Abid, Zakia; Habeeb, Md. Aejaz; Habibullah, Chitoor Mohammed
In: Journal of Applied Microbiology, vol. 103, iss. 6, pp. 2353-2360, 2007.
@article{Tiwari_2007,
title = {A simple multiplex PCR assay for diagnosing virulent Helicobacter pylori infection in human gastric biopsy specimens from subjects with gastric carcinoma and other gastro-duodenal diseases},
author = {Santosh K. Tiwari and Aleem Ahmed Khan and G. Manoj and S. Ahmed and Zakia Abid and Md. Aejaz Habeeb and Chitoor Mohammed Habibullah},
url = {https://doi.org/10.1111%2Fj.1365-2672.2007.03478.x},
doi = {10.1111/j.1365-2672.2007.03478.x},
year = {2007},
date = {2007-09-01},
urldate = {2007-09-01},
journal = {Journal of Applied Microbiology},
volume = {103},
issue = {6},
pages = {2353-2360},
publisher = {Oxford University Press (OUP)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
0000
Reddy, M. Pavan; Srilakshmi, Mondreti; Maryam, Saulah
Prevalence of hypertension in children in age group 6-14 years: a descriptive observational study from Hyderabad Journal Article
In: International Journal of Medicine and Public Health, vol. 15, iss. 4, pp. 2046-2050, 0000, ISSN: 2230-8598.
@article{Reddy_2025,
title = {Prevalence of hypertension in children in age group 6-14 years: a descriptive observational study from Hyderabad},
author = {M. Pavan Reddy and Mondreti Srilakshmi and Saulah Maryam},
url = {https://www.ijmedph.org/Uploads/Volume15Issue4/368.%203799.%20IJMEDPH_IMRP_2046-2050.pdf},
doi = {10.70034/ijmedph.2025.4.368},
issn = {2230-8598},
journal = {International Journal of Medicine and Public Health},
volume = {15},
issue = {4},
pages = {2046-2050},
abstract = {Background: Blood pressure is considerably lower in children than adults but almost always increases steadily throughout the first two decades of life. Hypertension is one of the commonest diseases with an estimated worldwide prevalence of 1 billion. The prevalence of hypertension in children is reported to be 1-3%. Elevated blood pressure in children and adolescents may be an early expression of essential hypertension in adulthood. The objective is to determine the prevalence of hypertension in children in age group 6-14 years.
Materials and Methods: This prospective observational cross-sectional study was carried out in Children aged between 6 – 14 years attending Owaisi Hospital and research centre (DCMS) for routine immunisation and their siblings during the study period May 2024 to April 2025.
Results: In males Prevalence of Hypertension was 8.52% and in females Prevalence of Hypertension was 8.72%. Overall Prevalence of Hypertension was 8.61 %. In males, among 28 children with positive family H/o of hypertension, 4 (14.29%) were hypertensive. In females, among 25 children with positive family H/o of hypertension, 5 (20.00%) were hypertensive.
Conclusion: Prevalence of Hypertension was 8.61%. In males Prevalence of Hypertension was 8.52% and in females Prevalence of Hypertension was 8.72%. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Background: Blood pressure is considerably lower in children than adults but almost always increases steadily throughout the first two decades of life. Hypertension is one of the commonest diseases with an estimated worldwide prevalence of 1 billion. The prevalence of hypertension in children is reported to be 1-3%. Elevated blood pressure in children and adolescents may be an early expression of essential hypertension in adulthood. The objective is to determine the prevalence of hypertension in children in age group 6-14 years.
Materials and Methods: This prospective observational cross-sectional study was carried out in Children aged between 6 – 14 years attending Owaisi Hospital and research centre (DCMS) for routine immunisation and their siblings during the study period May 2024 to April 2025.
Results: In males Prevalence of Hypertension was 8.52% and in females Prevalence of Hypertension was 8.72%. Overall Prevalence of Hypertension was 8.61 %. In males, among 28 children with positive family H/o of hypertension, 4 (14.29%) were hypertensive. In females, among 25 children with positive family H/o of hypertension, 5 (20.00%) were hypertensive.
Conclusion: Prevalence of Hypertension was 8.61%. In males Prevalence of Hypertension was 8.52% and in females Prevalence of Hypertension was 8.72%.
Materials and Methods: This prospective observational cross-sectional study was carried out in Children aged between 6 – 14 years attending Owaisi Hospital and research centre (DCMS) for routine immunisation and their siblings during the study period May 2024 to April 2025.
Results: In males Prevalence of Hypertension was 8.52% and in females Prevalence of Hypertension was 8.72%. Overall Prevalence of Hypertension was 8.61 %. In males, among 28 children with positive family H/o of hypertension, 4 (14.29%) were hypertensive. In females, among 25 children with positive family H/o of hypertension, 5 (20.00%) were hypertensive.
Conclusion: Prevalence of Hypertension was 8.61%. In males Prevalence of Hypertension was 8.52% and in females Prevalence of Hypertension was 8.72%.
Koti, Vijaya Rekha; Owaisi, Nooruddin; Asraruddin, Mohammed; Hussain, Syed Asrar
A study on efficacy of unilateral spinal anesthesia with low dose hyperbaric bupivacaine Journal Article
In: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery, vol. 27, iss. 1, pp. 4960-4966, 0000, ISSN: 1001-1781.
@article{Koti_2023d,
title = {A study on efficacy of unilateral spinal anesthesia with low dose hyperbaric bupivacaine},
author = {Vijaya Rekha Koti and Nooruddin Owaisi and Mohammed Asraruddin and Syed Asrar Hussain},
url = {https://www.lcebyhkzz.cn/article/view/2023/4960.pdf},
issn = {1001-1781},
journal = {Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery},
volume = {27},
issue = {1},
pages = {4960-4966},
abstract = {Background and Objectives: Unilateral spinal anaesthesia is a promising alternative to traditional, widely used techniques of central neuraxial blocks, as it restricts markedly the anaesthetized area thereby, decreases the risk of adverse events and complications. The present study was taken up to assess the hemodynamic effects of low dose 1.5 ml (7.5 mg) of 0.5% hyperbaric Bupivacaine and also to assess the level achieved and duration of block. Methods: The present one year clinical trial was conducted in the Department of Anesthesiology, during the period of one year at Deccan College of Medical Sciences, affiliated to Owaisi Hospital and Princess Esra Hospital, Hyperabadon 100 ASA II and III patients undergoing unilateral lower limb surgery under unilateral spinal anaesthesia with bupivacaine. 1.5 ml of (7.5 mg) 0.5% bupivacaine heavy was injected with patient in lateral position with the limb to be operated on the lower side. Results: In this study out of 100 patients studied 72 (72%) were males with male to female ratio of 2.57:1. Majority of the patients (45%) were aged between 46 to 60 years. Overall mean age was 47.79 years and mean weight was 57.90 Kgs. The SBP, DBP and MBP showed a gradual fall with maximum fall noted at 40 minutes and gradually increased, subsequently reaching the baseline levels at 90 minutes. The maximum increase in HR was seen at 40 minutes after giving spinal and it gradually reduced coming to baseline levels at 90 minutes. Maximum sensory level of L1 was achieved. The block remained unilateral in 74.8% of the cases. Motor blockade was adequate in the limb to be operated. Conclusion: Subarachnoid block with 1.5 mL (7.5 mg) of 0.5% hyperbaric bupivacaine used in this study does not produce any adverse hemodynamic changes and lasts for short duration that is 90 minutes and can be used in surgeries of shorter duration.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Background and Objectives: Unilateral spinal anaesthesia is a promising alternative to traditional, widely used techniques of central neuraxial blocks, as it restricts markedly the anaesthetized area thereby, decreases the risk of adverse events and complications. The present study was taken up to assess the hemodynamic effects of low dose 1.5 ml (7.5 mg) of 0.5% hyperbaric Bupivacaine and also to assess the level achieved and duration of block. Methods: The present one year clinical trial was conducted in the Department of Anesthesiology, during the period of one year at Deccan College of Medical Sciences, affiliated to Owaisi Hospital and Princess Esra Hospital, Hyperabadon 100 ASA II and III patients undergoing unilateral lower limb surgery under unilateral spinal anaesthesia with bupivacaine. 1.5 ml of (7.5 mg) 0.5% bupivacaine heavy was injected with patient in lateral position with the limb to be operated on the lower side. Results: In this study out of 100 patients studied 72 (72%) were males with male to female ratio of 2.57:1. Majority of the patients (45%) were aged between 46 to 60 years. Overall mean age was 47.79 years and mean weight was 57.90 Kgs. The SBP, DBP and MBP showed a gradual fall with maximum fall noted at 40 minutes and gradually increased, subsequently reaching the baseline levels at 90 minutes. The maximum increase in HR was seen at 40 minutes after giving spinal and it gradually reduced coming to baseline levels at 90 minutes. Maximum sensory level of L1 was achieved. The block remained unilateral in 74.8% of the cases. Motor blockade was adequate in the limb to be operated. Conclusion: Subarachnoid block with 1.5 mL (7.5 mg) of 0.5% hyperbaric bupivacaine used in this study does not produce any adverse hemodynamic changes and lasts for short duration that is 90 minutes and can be used in surgeries of shorter duration.
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