@article{Ali_2025b,

title = {Rare meets routine: a case of sessile serrated lesion presenting as acute appendicitis},

author = {Syed Mubid Ali and Mohammed Abdullah Masood and Naushaba Tazeen and Asiya Tabassum and Idrees Akhtar Afroze and Atiya Begum and Shireen Adeeb Mujtaba Ali},

url = {https://ijpo.co.in/archive/volume/12/issue/3/article/24927/pdf},

doi = {10.18231/j.ijpo.11098.1680662831},

issn = {2394-6784},

year  = {2025},

date = {2025-10-17},

urldate = {2025-10-17},

journal = {Indian Journal of Pathology and Oncology},

volume = {12},

issue = {3},

pages = {279-282},

abstract = {Sessile serrated lesions (SSLs) are rare premalignant neoplasms usually arising in the colon but can also occur in the appendix, where their presentation often mimics acute appendicitis. We report the case of a 68‑year‑old male who presented with right lower abdominal pain and imaging findings suggestive of acute appendicitis with appendicular mucocele. The patient underwent appendectomy, and histopathological examination of the resected specimen revealed a sessile serrated lesion with marked dysplasia, without evidence of adenocarcinoma. Appendiceal SSLs are seldom reported in literature and may be overlooked due to their nonspecific clinical and radiological features. As SSLs are important precursors of colorectal carcinoma via the serrated neoplasia pathway, meticulous histopathological evaluation is crucial for accurate diagnosis. Early recognition, surgical excision, and colonoscopic follow‑up can help prevent malignant transformation. This case adds to the limited literature on appendiceal SSLs and emphasizes the need for increased awareness and documentation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Akhtar_2025,

title = {Vulvar leiomyoma: an unusual entity at a rare anatomical site},

author = {Mohtashim Idrees Akhtar and Naushaba Tazeen and Idrees Akhtar Afroze and Atiya Begum},

url = {https://ijnrd.org/papers/IJNRD2504372.pdf},

doi = {10.56975/ijnrd.v10i4.305369 },

issn = {2456-4184},

year  = {2025},

date = {2025-04-30},

urldate = {2025-04-30},

journal = {International Journal of Novel Research and Development},

volume = {10},

issue = {4},

pages = {d432-d436},

abstract = {Vulvar leiomyoma is a rare soft tissue tumor, accounting for only 0.03% of all gynecological tumors, which often leads to misdiagnosis. Leiomyoma is a type of smooth muscle tumor that primarily occurs in the uterus and is commonly known as a fibroid. However, extrauterine fibroids are quite rare and can be found in various locations, including the vulva, vagina, ovaries, urinary bladder, urethra, round ligaments, uterosacral ligaments, inguinal canal, retroperitoneum, sinonasal cavities, and even the kidneys. Vulvar leiomyoma typically affects women of reproductive age and can mimic conditions such as Bartholin’s cyst or abscess. Histologically, vulvar leiomyomas generally exhibit spindle-shaped cells, though other variants, such as the epithelioid subtype, have also been reported. In this report, we present a case of vulvar leiomyoma that was misdiagnosed as a Bartholin’s cyst before surgery.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Farzeen_2025,

title = {Exploring a rare entity: Myxoid liposarcoma on anterior abdominal wall},

author = { Mehrina Farzeen and Sumaiya Shireen and Naushaba Tazeen and Idrees Akhtar Afroze and Syed Asif Shah Harooni},

url = {https://jmas.in/?mno=215424},

doi = {10.5455/jmas.215424},

issn = {2231-1696},

year  = {2025},

date = {2025-01-31},

urldate = {2025-01-01},

journal = {Journal of Medical and Allied Sciences},

volume = {15},

issue = {1},

pages = {95-98},

publisher = {Deccan College of Medical Sciences},

abstract = {Myxoid liposarcoma is a soft tissue tumor. Out of all the malignant tumors, soft tissue tumors account for less than 1%, in which liposarcoma is the most common type of soft tissue tumor. The common site for liposarcoma is extremities and retroperitonium and on abdominal wall is exceptionally rare with only 22 cases reported so far. We report a case of 56 year old male patient presenting with anterior abdominal wall mass in left hypochondriac region of 6 months duration. There was no pain or discharge associated with it. On clinical examination, the mass was located on left upper quadrant of abdomen. Abdominal ultrasonography revealed well defined, hypoechoic, space occupying lesion. FNAC revealed scant fibroblast tissue. Trucut biopsy was advised. Radiological, clinical and cytological investigations were non- specific. An excision biopsy was performed and the sample was sent for histopathological examination. Gross examination revealed well circumscribed nodular myxoid mass, which was grey white in color. Microscopic examination revealed mesenchymal cells with myxoid rich stroma and cells show signet ring configuration. Pathological evaluation of surgical specimen is the gold standard for diagnosis. Complete excision with clear margin is the mainstay of treatment in view of its local recurrence. We report this case as myxoid liposarcomas are rarely seen in the clinic, here it has presented on an extremely unusual site, anterior abdominal wall.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mujeeb_2025,

title = {Cartilaginous metaplasia of thyroid nodule},

author = { Madeeha Mujeeb and Jasmeen Tabassum and Naushaba Tazeen and Idrees Akhtar Afroze and Imtiyaz Ahmed Khan},

url = {https://jmas.in/fulltext/154-1723005195.pdf?1752816740},

doi = {10.5455/jmas.214579},

issn = {2231-1696},

year  = {2025},

date = {2025-01-31},

urldate = {2025-01-31},

journal = {Journal of Medical and Allied Sciences},

volume = {15},

issue = {1},

pages = {92-94},

publisher = {Deccan College of Medical Sciences},

abstract = {Adenomatous goiter is the most common form of thyroid disease. Although degenerative changes like fibrosis, calcification, cystic changes and hemorrhagic tissue are commonly found, cartilaginous metaplasia is an unusual phenomenon in the thyroid gland. Heterotopic cartilage formation is a very rare finding in both neoplastic and non-neoplastic lesions. Only 2 cases have been reported so far. Here we present a case of a 65-year-old female who presented with a midline swelling in her neck for 2 months associated with difficulty in swallowing. The lymph nodes were not palpable and there were no pressure symptoms. Ultrasonography was suggestive of thyromegaly with large goiterous change in left lobe and isthmus of thyroid. Fine Needle Aspiration Cytology (FNAC) revealed Bethesda Category I lesion. The patient underwent left hemi-thyroidectomy. Microscopy revealed encapsulated lesions composed of variable-sized follicles filled with colloid. Cystic areas lined by benign follicular cells showing foci of cartilage were also observed. Consistent with diagnosis of adenomatoid goiter with cartilaginous metaplasia. This case shows a rare histopathological change in the thyroid nodular lesions.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2025c,

title = {Mesentric cyst with a twist},

author = { Juveria Fatima and Shaila Tasneem and Farha Naaz and Naushaba Tazeen and Idrees Akhtar Afroze and Syed Asif Shah Harooni},

url = {https://jmas.in/fulltext/154-1722832055.pdf?1755672275},

doi = {10.5455/jmas.214286},

issn = {2231-1696},

year  = {2025},

date = {2025-01-31},

urldate = {2025-01-31},

journal = {Journal of Medical and Allied Sciences},

volume = {15},

issue = {1},

pages = {88-91},

publisher = {Deccan College of Medical Sciences},

abstract = {With an incidence rate of 0.1-0.3% gastrointestinal stromal tumors (GIST) are rare to be found in extraintestinal locations known as extraintestinal GIST (EGIST). Mesenchymal in origin, they arise from interstitial cells of Cajal, a part of gastrointestinal autonomic nervous system (ANS). It is more common in males than females. GIST is mainly seen in stomach followed by small bowel, colon, rectum and esophagus. Incidence of EGIST is less than 1%. Patients with neurofibromatosis-1 has increased incidence of GIST. It can also present as Carney-Stratakis syndrome. GIST less than 2 cm is usually asymptomatic while GIST more than 2 cm presents with unexplained growth of abdomen, nausea, anemia, difficulty in swallowing, loss of appetite and weight loss. Herein we present a case of 31-yr old female, who presented with complaints of intermittent abdominal pain and was evaluated for infertility. Abdominal ultrasonography (USG) revealed cystic mass of mesentery. Computed tomography (CT) scan abdomen confirmed a cystic lesion with central necrosis arising from jejunal loops. Surgical excision of mesenteric cyst was performed and histopathological diagnosis of gastrointestinal tumor was given. Thus, high index of suspicion is required on part of pathologist to expect an EGIST mimicking as a mesenteric cyst.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2025d,

title = {Renal cell carcinomas’ hidden challenge: sarcomatoid differentiation uncovered},

author = {Syeda Yousufa Husna Fatima and Hafeza Farha Syeda and Naushaba Tazeen and Idrees Akhtar Afroze and Mohammed Abdul Majid Adil},

url = {https://jmas.in/fulltext/154-1723478384.pdf?1755843299},

doi = {10.5455/jmas.215330},

issn = {2231-1696},

year  = {2025},

date = {2025-01-31},

urldate = {2025-01-31},

journal = {Journal of Medical and Allied Sciences},

volume = {15},

issue = {1},

pages = {99-102},

publisher = {Deccan College of Medical Sciences},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tabassum_2025,

title = {Diagnostic and prognostic significance of platelet indices and platelet lymphocyte ratio in covid vs dengue: an observational study},

author = {Asiya Tabassum and T. S. Shamshuddeen and Idrees Akhtar Afroze},

url = {https://journals.lww.com/jdrntruhs/fulltext/2025/01000/diagnostic_and_prognostic_significance_of_platelet.8.aspx},

doi = {10.4103/jdrntruhs.jdrntruhs_170_22},

issn = {2950-5348},

year  = {2025},

date = {2025-01-01},

urldate = {2025-01-01},

journal = {Journal of Dr. NTR University of Health Sciences},

volume = {14},

issue = {1},

pages = {46-51},

abstract = {Background: Both SARS-CoV and dengue virus share the same symptoms in the early stages and at times causing misdiagnosis, coinfections are common creating difficulties for the health care workers. Aim: Efforts were made to utilize the hematology parameters, Mean platelet volume and Platelet lymphocyte ratio (PLR) in early segregation, diagnosis and predicting the severity and prognosis of the cases and to determine, if further investigations or referrals would be required. Material and Methods: Observational study was conducted with 100 confirmed cases of COVID-19 and dengue patients. Results: Patients with COVID-19 present with leucopenia or leucocytosis, with Lymphopenia as the most significant finding, Platelet counts were adequate but Mean platelet volume (MPV) is insignificant and increased levels of PLR are related with bad prognosis. In Dengue, the white blood cells (WBC) count shows progressive leucopenia with lymphocytic predominance with atypical lymphocytes, thrombocytopenia with increased MPV and decreased PLR help in early diagnosis of dengue infection. Conclusion: Complete blood count (CBC) is the most common and inexpensive test performed in patients and has capacity to segregate and diagnose Covid 19 and Dengue cases at an early stage so that isolation and prompt treatment can be started early, decreasing the lead time and help in combating the pandemic. PLR and MPV can be used to predict the prognosis and complications and have usefulness in monitoring treatment response. RT-PCR and dengue serology can be done on selected cases when required decreasing the burden on the health system and its resources.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2025g,

title = {Whispers of the ovary: a pathological journey through lymphangioma},

author = {Juveria Fatima and Naushaba Tazeen and Asiya Tabassum and Idrees Akhtar Afroze},

url = {https://journals.lww.com/tjima/fulltext/2025/01000/whispers_of_the_ovary__a_pathological_journey.14.aspx},

doi = {10.4103/tjima.tjima_15_25},

isbn = {3050-6158},

year  = {2025},

date = {2025-01-01},

urldate = {2025-01-01},

journal = {Telangana Journal of IMA},

volume = {5},

issue = {1},

pages = {44-47},

abstract = {Lymphangioma of the ovary is an exceedingly rare benign tumor, characterized by the proliferation of lymphatic vessels. Typically presenting in childhood or early adulthood, these lesions can often be asymptomatic but may occasionally lead to abdominal pain, pelvic mass, or complications such as torsion or hemorrhage. Diagnosis is primarily achieved through imaging techniques such as ultrasound, computed tomography, or magnetic resonance imaging, which help differentiate lymphangiomas from other ovarian masses. Histopathological examination is essential for definitive diagnosis, revealing cystic spaces lined by the endothelial cells and a lymphatic-like structure. Management usually involves surgical intervention, with complete excision being the preferred treatment to prevent recurrence. Given the rarity of ovarian lymphangiomas, there is limited literature on the long-term outcomes; however, most cases report favorable prognoses following appropriate surgical resection. This abstract aims to summarize the clinical features, diagnostic approaches, and treatment options for ovarian lymphangioma while emphasizing the need for awareness of this rare entity among clinicians to facilitate timely diagnosis and intervention. Further studies are warranted to better understand the pathogenesis and optimal management strategies for this unusual tumor.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Naaz_2024,

title = {Epidermoid cyst in uterine cervix–a rare and unusual location},

author = {Farha Naaz and Asfiya Fatima and Idrees Akhtar Afroze},

url = {https://www.worldwidejournals.com/indian-journal-of-applied-research-(IJAR)/fileview/epidermoid-cyst-in-uterine-cervix-a-rare-and-unusual-location_May_2024_1521776051_9602538.pdf},

doi = {10.36106/ijar},

issn = {2249-555X},

year  = {2024},

date = {2024-05-31},

urldate = {2024-05-31},

journal = {Indian Journal of Applied Research},

volume = {15},

issue = {5},

pages = {61-62},

abstract = {Cervical epidermoid cysts and uncommon benign cystic lesions were identied in a 50-year-old woman. The patient presented with heavy menstrual bleeding and lower abdominal pain, and after initial treatment with endometrial biopsy and hemostatic uterine curettage, a total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. The gross examination of the specimen revealed a hypertrophied cervix with a cyst lled with grey-white substance, as well as a polypoidal mass in the fundus and intramural broids. Histopathological examination conrmed the diagnosis of a cervical epidermoid cyst as an incidental nding. Squamous metaplasia was conned to the cervical mucosa. The precise etiology remains unclear, but post-parturient implantation of vestigial embryonic tissue might be a contributing factor as there is no other associated etiology in this case. This case report emphasizes the importance of considering epidermoid cysts in the differential diagnosis of cervical masses and highlights the need for further research to better understand the formation and management of these rare cysts.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2024,

title = {Ovarian hydatid cyst-a rare entity: a case report},

author = {Hafeza Syeda Farha Sultana and Samia Mohammed and Idrees Akhtar Afroze},

url = {https://www.worldwidejournals.com/indian-journal-of-applied-research-(IJAR)/fileview/ovarian-hydatid-cyst-a-rare-entity-a-case-report_May_2024_7615171205_7202728.pdf},

doi = {10.36106/ijar},

issn = {2249-555X},

year  = {2024},

date = {2024-05-31},

urldate = {2024-05-31},

journal = {Indian Journal of Applied Research},

volume = {14},

issue = {5},

pages = {66-67},

abstract = {Hydatid disease is a zoonosis caused by the transmission of the larval stage of Echinococcus granulosus (dog tapeworm) either by consuming contaminated food and water or due to hand to mouth transmission from infested animals or partially cooked meat. Humans are the accidental host. Hydatid cyst of ovary is an extremely rare presentation accounting for 0.2-1% of all cases. A 47-year-old woman presented to the surgery department of Owaisi Group of Hospitals (PEH) with a chief complaint of abdominal pain for 1 week. USG examination revealed bilateral simple ovarian cysts and CT scan Fndings showed bilateral complex ovarian cysts. Routine investigations were normal. Surgery was performed for suspected ovarian cyst. The cysts were extracted and sent for HPE which confrmed the diagnosis of hydatid ovarian cyst. The incidence of hydatid cyst in the female reproductive system is less than 0.5% of all cases. The clinician must have a high index of suspicion whenever cystic lesions of pelvis are found as any spillage while operating may lead to anaphylactic shock and recurrence. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kareem_2024,

title = {A case report on pituitary neuroendocrine tumor (PNET) with oncocytic change},

author = {Sana Munazza Kareem and Idrees Akhtar Afroze},

url = {https://www.worldwidejournals.com/indian-journal-of-applied-research-(IJAR)/fileview/a-case-report-on-pituitary-neuroendocrine-tumor-pitnet-with-oncocytic-change_May_2024_5817170215_4803207.pdf},

doi = {10.36106/ijar},

issn = {2249-555X},

year  = {2024},

date = {2024-05-31},

urldate = {2024-05-31},

journal = {Indian Journal of Applied Research},

volume = {14},

issue = {5},

pages = {83-84},

abstract = {Neuroendocrine tumors (NET) originate from the diffuse neuroendocrine system. These can arise in almost every organ of the body, although they are most commonly found in the gastrointestinal tract and respiratory system. The skull base and sellar region are extremely rare sites for neuroendocrine carcinoma. Intracranial originating is lower than 0.74 %. A 55year old male was admitted in the neurosurgery department of Owaisi Group of Hospitals (PEH) with chief complaint of severe headache for 15 days, associated with giddiness, nausea and left eye vision disturbance. MRI showed Pituitary macroadenoma. Surgery was performed and the excised specimen of Pituitary adenoma was sent for HPE which revealed that the lesion was a Neuroendocrine tumor. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mahmood_2025,

title = {Correlation between histopathological grades of oral squamous cell carcinoma and tobacco consumption a cross sectional assessment},

author = {Aiman Mahmood and Hafeza Syeda Farha Sultana and Idrees Akhtar Afroze},

url = {https://www.makhillpublications.co/files/published-files/mak-rjms/2024/4-147-151.pdf},

doi = {10.36478/makrjms.2024.4.147.151},

issn = {1815-9346},

year  = {2024},

date = {2024-01-06},

urldate = {2024-01-06},

journal = {Research Journal of Medical Sciences},

volume = {18},

issue = {4},

pages = {147-151},

abstract = {Oral squamous cell carcinoma (OSCC) is a prevalent form of cancer associated with tobacco consumption. Histopathological grading provides insights into the aggressiveness and prognosis of OSCC. This study aims to explore the correlation between the histopathological grades of OSCC and the history and extent of tobacco consumption in patients. A cross‐sectional study was conducted with 200 participants diagnosed with OSCC. Histopathological grades were determined using standard criteria and were correlated with detailed tobacco consumption history, including duration, frequency and type. Statistical analyses were conducted to assess the relationship between the grades of OSCC and tobacco use patterns. The study found a statistically significant correlation between higher histopathological grades of OSCC and increased levels of tobacco consumption. A noticeable pattern of more severe carcinoma grades was evident among heavy and long‐term tobacco users. The results also highlighted specific histopathological characteristics that were more prevalent in association with certain types and patterns of tobacco use. The findings suggest a strong link between tobacco consumption and the severity of histopathological grades of OSCC. These results underscore the critical need for targeted tobacco cessation programs and early screening for OSCC, especially among populations with high tobacco use. Further research is recommended to explore the mechanisms underlying the relationship between tobacco‐induced carcinogenesis and OSCC progression.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tabassum_2024,

title = {Assessment of HER2 amplification in breast carcinoma: a cross‐sectional study comparing IHC and Fish},

author = {Jasmeen Tabassum and Lubna Yasmeen and Idrees Akhtar Afroze},

url = {https://makhillpublications.co/files/published-files/mak-rjms/2024/113-117.pdf},

doi = {10.59218/makrjms.2024.3.113.117},

issn = {1815-9346},

year  = {2024},

date = {2024-01-03},

urldate = {2024-01-03},

journal = {Research Journal of Medical Sciences},

volume = {18},

pages = {113-117},

abstract = {This cross‐sectional study aims to compare the effectiveness of Immunohistochemistry (IHC) and Fluorescence In Situ Hybridization (FISH) in assessing HER2 amplification in breast carcinoma, which is pivotal for treatment strategy and prognosis. The study encompassed 200 patients diagnosed with breast carcinoma. HER2 status was initially assessed using IHC. Cases with equivocal or positive IHC results were further evaluated using FISH to confirm HER2 gene amplification. Statistical analysis was conducted to determine the concordance and discordance between the two methods. The results demonstrated a certain percentage of cases showing HER2 amplification. Concordance rates between IHC and FISH were high, with some discordant results analyzed to understand the causes. The study provided detailed figures on the sensitivity, specificity and predictive values of IHC in comparison to FISH, discussing the implications of these findings in clinical practice. This study underscores the significance of a complementary diagnostic strategy combining both IHC and FISH for the reliable determination of HER2 status in breast carcinoma. The findings advocate for an integrated approach to enhance accuracy, improve treatment decisions and ultimately, patient outcomes in breast cancer care.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shireen_2024,

title = {Prevalence of high grade dysplasia in colorectal polyp cross sectional analysis in tertiary care hospital},

author = {Sumaiya Shireen and Sumayya Aijaz and Idrees Akhtar Afroze},

url = {https://makhillpublications.co/files/published-files/mak-rjms/2024/100-103.pdf},

doi = {10.59218/makrjms.2024.3.100.103},

isbn = {1815-9346},

year  = {2024},

date = {2024-01-02},

urldate = {2024-01-02},

journal = {Research Journal of Medical Sciences},

volume = {18},

issue = {3},

pages = {100-103},

abstract = {The incidence of colorectal cancer had been increasing globally, with high‐grade dysplasia in colorectal polyps recognized as a significant precursor to malignancy. This study aimed to determine the prevalence of high‐grade dysplasia among patients with colorectal polyps in a tertiary care hospital setting.A cross‐sectional study was conducted involving 300 patients who underwent colonoscopy and were diagnosed with colorectal polyps at a tertiary care hospital. The presence of high‐grade dysplasia was confirmed through histopathological examination. Data regarding patient demographics, polyp characteristics and histological findings were collected and analyzed. The study found that high‐grade dysplasia was present in a significant proportion of colorectal polyps, particularly among patients aged 50 years and older, with a prevalence of 30% compared to 13.3% in younger patients. The odds of high‐grade dysplasia were notably higher in polyps >10mm in size (OR = 2.3) and located in the colon (OR = 1.9). Gender did not show a significant association with the presence of high‐grade dysplasia. Additionally, while an increasing number of polyps showed a higher prevalence of high‐grade dysplasia, this association did not reach statistical significance. All findings were statistically analyzed to ascertain the strength and significance of these associations, with age, polyp size and location showing notable correlations with the occurrence of high‐grade dysplasia in colorectal polyps. This study provided valuable insights into the prevalence of high‐grade dysplasia in colorectal polyps in a tertiary hospital setting. The findings informed clinicians and health policymakers about the importance of screening and surveillance strategies in the early detection and prevention of colorectal cancer.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Naaz_2023,

title = {Clinico-pathological correlation of inflammatory dermatoses in a tertiary care hospital},

author = {Farha Naaz and Naushaba Tazeen and Mohammed Mustafa Khan and Idrees Akhtar Afroze and Khatija Shameem and Atiya Begum and Asiya Tabassum and Sobia Afreen},

url = {https://jcdronline.org/index.php/JCDR/article/view/4062/3938},

issn = {0975-3583},

year  = {2023},

date = {2023-12-06},

urldate = {2023-12-06},

journal = {Journal of Cardiovascular Disease Research},

volume = {14},

issue = {12},

pages = {2525-2534},

abstract = {Inflammatory dermatoses encompass a variety of histologic patterns that affect different segments of the skin. Skin is a complex organ having many functions. Epidermis with melanocytic system, dermis with adnexa and subcutis are its main components. Skin diseases are highly prevalent in developing countries, occur commonly amongst all age groups and range from simple inflammatory lesions to fatal neoplasms. As clinical presentation can be similar for various skin lesions, histopathological examination remains the gold standard for accurate diagnosis and serves as a guide to clinician for appropriate management. The objective of this study is to observe and analyze the spectrum of inflammatory dermatological lesions through Histopathological examination. Through this we try to find out the common skin lesions in an urban population, evaluate its correlation with age and gender, and correlate the clinical diagnosis and histopathological examination. Out of 50 skin biopsies studied, 31 were female and 19 were male. Age of the patients range from 11 to 70 years in which peak age was 21-30 years. Leprosy is the most common lesion in our study accounting for 16 out of 50 cases studied. Next common lesion was Psoriasis, accounting for 10 out of 50 cases studied. Out of these 50 cases, 44 cases correlated with clinical diagnosis and the rest of cases did not correlate with given clinical diagnosis. The present study emphasizes the role of histopathological examination as a valuable diagnostic tool to understand the pathology of inflammatory dermatoses and provides a significant insight into trend of inflammatory skin lesions in the specific sub-population of Hyderabad, Telangana, India.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tabassum_2022b,

title = {Covid-19 vs dengue-role of WBC counts in segregation of cases at an early stage with special reference to NLR as a diagnostic and prognostic factor},

author = {Asiya Tabassum and Idrees Akhtar Afroze and Sumayya Begum },

url = {https://www.ijmsir.com/asset/images/uploads/16560077756647.pdf},

issn = {2458-868X},

year  = {2022},

date = {2022-05-31},

urldate = {2022-05-31},

journal = {International Journal of Medical Science and Innovative Research},

volume = {7},

issue = {3},

pages = {155-162},

abstract = {Both SARS-CoV and dengue virus can present as mild diseases which subsides by itself or can get severe resulting in a patient’s death. In tropical and subtropical countries, where dengue epidemics are commonly seen, COVID-19 can be easily misdiagnosed with dengue, because they present with common symptoms in the

initial stages but have different clinical management which makes it challenging for the health care  professionals to diagnose in the early stages. Moreover, there have been few cases reported where there was co infection by the viruses, making the picture still more confusing and challenging for the doctors. In poor and developing countries, access to specific diagnostic tests, the funding for them is limited and complete blood count (CBC) is the single most common test performed in patients. This study aimed to evaluate, analyse and compare the WBC count, differential leucocyte count and Neutrophil lymphocyte ratio (NLR) among COVID-19 and dengue cases. An attempt was made in diagnosing these two conditions with the above parameters at an early stage and to determine if further investigations or referrals would be required. Inflammatory marker NLR was also analyzed with series of samples of the patients during their hospital stay in predicting the outcome of cases. This study was a retrospective one done for duration of 1 year between Jan 2021 and Jan 2022 and included two different groups of patients, COVID-19 and dengue patients. A total of 106 cases of confirmed COVID-19 and 100 cases of dengue were included in the study. We propose utilizing the WBC count, differential count and NLR in early diagnosis and segregation of COVID 19 and dengue cases so that patients with COVID 19 can be isolated at the earliest, prompt treatment be given, decreasing the lead time, trying to combat the pandemic and the patients with dengue can be treated accordingly avoiding the complications. RT-PCR and dengue serology can be done on selected cases when required decreasing the burden on the health system and its resources. Patients with COVID-19 present with leucopenia or Leucocytosis, with Lymphopenia as the most significant finding, which is a useful and reliableindicator of the severity of the disease. Neutrophil lymphocyte ratio (NLR) was increased in majority of these cases and is described as an independent biomarker for indicating poor clinical outcomes in these patients. In contrast to COVID 19, the WBC count in dengue is characterized by progressive leucopenia with lymphocytic predominance and is associated with decreased NLR. Integrating the NLR in the diagnosis and prognosis of patients with COVID-19 and dengue would help in identification and prediction of cases with increased severity so that prompt treatment can be done

decreasing the mortality and for better outcome of these patients. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shamshuddeen_2022,

title = {Study on immunoexpression of beta catenin and Ki 67 in oral squamous cell carcinomas},

author = {T. S. Shamshuddeen and Asiya Tabassum and Naushaba Tazeen and Idrees Akhtar Afroze},

url = {https://sciencescholar.us/journal/index.php/ijhs/article/view/7623/3841},

doi = {10.53730/ijhs.v6ns3.7623},

issn = {2550-696X},

year  = {2022},

date = {2022-05-20},

urldate = {2022-05-20},

journal = {International Journal of Health Sciences},

volume = {6},

issue = {S3},

pages = {6963-6971},

publisher = {Universidad Tecnica de Manabi},

abstract = {Cancer is a global health problem. It is the third most common cause of death.1 Among the malignant lesions of the oral cavity squamous cell carcinoma represents the most common cancer. It comprises about 90% of oral cancers.2 To elucidate the expression of immunohistochemical localization of β-catenin, To evaluate proliferative index (ki 67) in oral squamous cell cancers. To stusdy the correlation between β-catenin expression, ki 67 expression and tumor differentiation. Comparative case control study. The study was done in Department of Pathology and E.N.T in a tertiary care hospital. 1 year. patients with signs and symptoms of oral squamous cell carcinoma and investigated in a tertiary care hospital setting. A total of 104 (84 Cases and 20 Controls) were included in the study. Biopsy specimens received to pathology department where gross examination of the specimens was done. Aberrant expression of β-catenin in different histological grades is statistically significant. The p-value is .001361. Aberrant expression of β-catenin increased with increase in histological grade. It can be concluded that β-catenin is a significant factor in predicting the histological grade in patients with SCC.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shamshuddeen_2022b,

title = {Study on immunoexpression of beta catenin and Ki 67 in oral squamous cell carcinomas},

author = {T. S. Shamshuddeen and Asiya Tabassum and Naushaba Tazeen and Idrees Akhtar Afroze},

url = {https://sciencescholar.us/journal/index.php/ijhs/article/view/7623/3841},

doi = {10.53730/ijhs.v6nS3.7623 },

issn = {2550-696X},

year  = {2022},

date = {2022-05-09},

urldate = {2022-05-09},

journal = {International Journal of Health Sciences},

volume = {6},

issue = {S3},

pages = {6963-6971},

abstract = {Cancer is a global health problem. It is the third most common cause of death.1 Among the malignant lesions of the oral cavity squamous cell carcinoma represents the most common cancer. It comprises about 90% of oral cancers.2 To elucidate the expression of immunohistochemical localization of β-catenin, To evaluate proliferative index (ki 67) in oral squamous cell cancers. To stusdy the correlation between β-catenin expression, ki 67 expression and tumor differentiation. Comparative case control study. The study was done in Department of Pathology and E.N.T in a tertiary care hospital. 1 year. patients with signs and symptoms of oral squamous cell carcinoma and investigated in a tertiary care hospital setting. A total of 104 (84 Cases and 20 Controls) were included in the study. Biopsy specimens received to pathology department where gross examination of the specimens was done. Aberrant expression of β-catenin in different histological grades is statistically significant. The p-value is .001361. Aberrant expression of β-catenin increased with increase in histological grade. It can be concluded that β-catenin is a significant factor in predicting the histological grade in patients with SCC. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Asfiya_2021,

title = {Role of eosinophil count for early recognition and prognostication of Covid-19},

author = {Khanam Asfiya and Syed Mohammed Ali Mehdi and Idrees Akhtar Afroze and Fawwad M. Shaikh and Sumayya Begum and Nabila Afsar},

url = {https://www.ijmsir.com/asset/images/uploads/16281658002972.pdf},

issn = {2458-868X},

year  = {2021},

date = {2021-07-01},

urldate = {2021-07-01},

journal = {International Journal of Medical Science and Innovative Research},

volume = {6},

issue = {4},

pages = {224-232},

abstract = {Background: The Severe Respiratory Distress Syndrome caused by the COVID-19 virus has turned into a pandemic and has caused havoc worldwide and is still continuing to do so. In such times, there is a need for a diagnostic tool which eases the technique of detecting the disease and is also less time consuming. Thus an analogy was established between the Covid-19 positive RT-PCR cases and their blood eosinophil levels. Aims: To study the diagnostic and Prognostic significance of eosinophil counts in Covid-19 infections. Settings and Design: This study that was conducted in a tertiary health care centre was done by analysing the eosinophil counts of the patients and there by correlating them with the progression of the disease. Materials and Methods: 105 Patients who tested positive by RT-PCR for COVID-19 were enrolled for this study and their complete blood count report was obtained. Statistical Analysis: The data analysis was done in proportions and percentages. The statistical test of significance applied manually to the cross table was chi square test. Result: Based on the outcome it was noted that 70.50% cases were eosinopenic on admission. Also drop in eosinophil count(93.75% of the cases) or the absence of eosinophils on presentation correlated with poor prognosis. Conclusion: Eosinopenia can help in early detection of Covid-19 infection and the variation in the eosinophil count can help in gauging the prognosis and the outcome of the disease.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hussain_2021b,

title = {Role of neutrophil/lymphocyte ratio as a prognostic marker of cerebrovascular accident},

author = {Syed Arshad Hussain and Idrees Akhtar Afroze and T. S. Shamshuddeen},

url = {https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/fileview/role-of-neutrophil-lymphocyte-ratio-as-a-prognostic-marker-of-cerebrovascular-accident_May_2021_6510266714_9307901.pdf},

doi = {10.36106/ijsr},

issn = {2277-8179},

year  = {2021},

date = {2021-05-01},

urldate = {2021-05-01},

journal = {International Journal of Scientific Research},

volume = {10},

issue = {5},

pages = {76-77},

abstract = {NA},

keywords = {},

pubstate = {published},

tppubtype = {article}

}