@article{Ashraf_2024,

title = {Study of testosterone levels in type II diabetes mellitus male patients in Telangana population},

author = {Syed Mustafa Ashraf and Syeda Asma Gulnaaz},

url = {https://academicmed.org/Uploads/Volume6Issue4/83.%20[3614.%20JAMP_Dr%20Makandar%20U.K]%20415-417.pdf},

doi = {10.47009/jamp.2024.6.4.83 },

issn = {2687-5365},

year  = {2024},

date = {2024-07-26},

urldate = {2024-07-26},

journal = {International Journal of Academic Medicine and Pharmacy},

volume = {6},

issue = {4},

pages = {405-407},

abstract = {Background: Type-II DM is a major health problem globally; it affects mainly the cardio-vascular system, including the lipid profile, and also impairs hormone pathways like insulin and sex hormones in males, leading to impotency. Materials and Methods: 195 (one hundred ninety-five) type II DMs of different age groups were studied and compared with 190 normal (controlled) groups. The blood investigation included FBS and PP. Blood urea, serum creatinine, Hbs.A1C, lipid profile, urine albumin, creatinine ratio, and serum testosterone were estimated by chemiluminescence immune assay and HbA1c by HPLC. Results: The BMI, age, HBSA1C, and serum testosterone level were compared with the control group, and the p value was highly insignificant (p<0.001). Conclusion: It is confirmed that type II DM patients have lower serum testosterone levels. Diabetes mellitus affects the vascularity of vital organs and impairs the normal functions of tests, leading to male

sterility. The present study helps physicians or endocrinologists treat such patients efficiently.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gulnaaz_2024,

title = {Comparative study of antioxidant vitamins and enzymes in alcoholic liver diseases in Telangana population},

author = {Syeda Asma Gulnaaz and Syed Mustafa Ashraf},

url = {https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue7,Article133.pdf},

doi = {10.5281/zenodo},

issn = {0975-1556},

year  = {2024},

date = {2024-06-26},

urldate = {2024-06-26},

journal = {International Journal of Pharmaceutical and Clinical Research},

volume = {16},

issue = {7},

pages = {811-814},

abstract = {Background: The liver is the largest site of metabolism in the body. It also provides the primary site for alcohol metabolism. It leads to oxidative damage due to alcohol, which causes a decrease in anti-oxidant enzymes and chemicals. Method: 60 alcoholic liver disease patients were compared with the same number of healthy (controlled) groups. Clinical and laboratory investigations were carried out using venous blood plasma vit. E levels by Baker Hatal method, ascorbic acid by the Teitz method, and SVD by the Beers-Seizer method. Results: The comparison of non-enzymatic oxidant parameters. Ascorbic acid, vitamin E, and the comparison of anti-oxidant enzymes SOD, GPX in both groups were statistically highly significant (p<0.00). Conclusion: The present study indicates that alcohol promotes oxidative stress, a major cause of alcohol toxicity in liver Vitamin E is a potential therapeutic agent for alcohol-induced oxidative damage in liver.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fathima_2023,

title = {Self-directed learning: health care professional's perspective-a study},

author = {Munazza Fathima and Syeda Noorul Absar and Ghulam Subhani and Neeraj Sadiq and Mohammed Khaleel and Mohammed Mohsin and Madhipati Sai Krishna},

url = {http://ajms.alameenmedical.org/ArticlePDFs/6%20AJMS%20V16.N3.2023%20p%20216-222.pdf},

issn = {0974-1143},

year  = {2023},

date = {2023-07-01},

urldate = {2023-07-01},

journal = {Al Ameen Journal of Medical Sciences},

volume = {16},

issue = {3},

pages = {216-222},

abstract = {Background: Self-directed learning is a teaching learning method emphasized as a part of newly developed competency based medical education (CBME) which was implemented in 2019 and since then it is an active part of the curriculum. Aims and Objectives: To evaluate the shift in learning process from teacher based education to a student based instruction by assessment of Self-Directed Learning Readiness (SDLR) scores among health professional’s medical students, nursing students, Physiotherapy and Pharmacy students. Material and Methods: A questionnaire based prospective observational study was done in Deccan College of Medical Sciences from Aug 2022 to October 2022. Statistical analysis was done using R language. Results: Maximum SDLR score obtained was 105 and minimum was 21. Scores <80 were considered low and > 80 as high. SDLR scores of most students were low. The scores were comparable to other studies like a South Indian study done who reported a mean SDLRS score in the low readiness category and some studies scores were high readiness to learn. Conclusion: Most students are ready for self- directed learning but their scores need to improve.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sadiq_2023,

title = {A medical student’s insight into set induction: a cross sectional study},

author = {Neeraj Sadiq and Syyeda Anees and Ghulam Subhani and Mohammed Mohsin and Madhipati Sai Krishna},

url = {http://ajms.alameenmedical.org/ArticlePDFs/8%20AJMS%20V16.N2.2023%20p%20140-145.pdf},

issn = {0974-1143},

year  = {2023},

date = {2023-04-01},

urldate = {2023-04-01},

journal = {Al Ameen Journal of Medical Sciences},

volume = {16},

issue = {2},

pages = {140-145},

abstract = {Background: Set induction are preliminary measures taken by the teacher to start effectual classroom instruction and training. Objectives: The aim of the study is to familiarize the mode of set induction to MBBS students. To know the perceptions of MBBS students batch wise towards set induction as an introductory step

in teaching/learning method. Methods: A Cross sectional study with cluster sampling was done on of second, third and fourth year MBBS students of Deccan College of Medical Sciences. After taking informed consent orally they were introduced to different types of set induction namely case -based scenarios, narratives and

audio visual aids, then a questionnaire was given and results were noted and analyzed statistically in R-language software. Results: Among the 312 students that participated, 208 students (66%) answered all questions. Set induction impacts the students immensely and has significant role to play for all the batches 2020(2st year), 2019(3rdYear), 2020(4thyear). There is a statistically significant difference between batches regarding their perceptions towards set induction and was found to be engrossing and applicable. Conclusion: Set induction must be deliberately designed to facilitate its incorporation for smooth teaching learning process. Case based scenario introduction is the most preferred by students, closely followed by narration based and lastly by audio-visual based introduction.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2023e,

title = {Experimental evaluation of anti-ulcer potential of nigella sativa oil in gastric ulcers in albino rats},

author = {Shaima Zafer Khan and Ghulam Subhani and Ayesha Vaseem and Neeraj Sadiq and Mohammed Mohsin},

url = {https://www.jpccr.eu/pdf-162337-88551?filename=Experimental%20evaluation.pdf},

doi = {10.26444/jpccr/162337},

issn = {1898-2395},

year  = {2023},

date = {2023-03-01},

urldate = {2023-03-01},

journal = {Journal of Pre-Clinical and Clinical Research},

volume = {17},

issue = {1},

pages = {10-15},

publisher = {Institute of Rural Health},

abstract = {Introduction and objective: Peptic ulcer is a gastrointestinal disease that is characterized by mucosal damage. Nigella sativa (NS) is a medicinal plant increasingly used in practice for treating gastrointestinal diseases. The aim of the study was to evaluate the antiulcer potential of Nigella sativa oil in Albino rats. Material and methods: The study utilized two methods of gastric ulcer induction in Albino rats. The Aspirin-induced gastric ulcer method consisted of 3 groups, with 6 rats in each group, which received pre-treatment once a day orally for 5 days. Group-1 (Control) animals received distilled water. Group-2 (Standard) animals received the standard drug, Ranitidine. Group-3 (Expermintal) animals received the test drug – Nigella sativa oil. The forced swim induced acute gastric ulceration method consisted of 3 groups i.e., control, standard, and test group with 6 rats in each group. After 5 days of respective pre-treatment, the animals were subject to a forced swim test. On day 7, 4 hours after Aspirin ingestion, the animals were sacrificed by stunning. The stomachs of the sacrificed animals was dissected for ulcer scoring. Results: In the Aspirin-induced ulcer method, the percentage protection from ulcer formation was 47.5% in the Nigella sativa group and 52.9% in the standard group. The effect of Nigella sativa oil in comparison to control was statistically significant (p value=0.03). In the forced swim induced acute gastric ulceration method, the percentage protection offered by Nigella sativa oil was 73%, whereas it was 69.6% in the Ranitidine group, and the effect of Nigella sativa oil in comparison to the effect of control was statistically significant (p value=0.03). Conclusions: The study demonstrated that NS oil has significant anti-ulcer potential in rats, which is comparable to the standard drug.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ashraf_2022,

title = {Comparative study to evaluate lipid profile in smoking and non-smoking individual at tertiary care centre},

author = {Syed Mustafa Ashraf and Mohammed Mudassir Ali and Mohammed Abdul Rafi and Syeda Asma Gulnaaz},

url = {https://sciencescholar.us/journal/index.php/ijhs/article/view/6002/2199},

doi = {10.53730/ijhs.v6nS2.6002 },

issn = {2550-6978},

year  = {2022},

date = {2022-04-13},

urldate = {2022-04-13},

journal = {International Journal of Health Sciences},

volume = {6},

issue = {S2},

pages = {4358-4365},

abstract = {Background:  Cigarette smoking, which is considered a major risk factor for atherosclerosis and coronary heart disease, may lead to changes in normal plasma lipid profile. The aim of the study was to evaluate the effect of cigarette smoking on lipid parameters in smokers and non-smokers. Material and Methods: A cross sectional comparative study was carried out in 200 subjects. The subjects were divided into two groups. Group A consisted of 100 smokers and Group B consisted of 100 Non-smokers. After overnight fasting following laboratory investigations were done in all subjects, Serum total cholesterol, Serum high density lipoprotein (HDL), Serum low density lipoprotein (LDL), Serum very low-density lipoprotein (VLDL), Serum triglyceride (TGL), Fasting blood sugar (FBS), Serum Creatinine, Urine for albumin, sugar and microscopic examination and the results of these tests were compared between the two groups.Results: All the values of lipid profile, TC, HDL, LDL, VLDL, TGL, were found to be significantly higher among the smokers compared to the non-smokers. The mean value of HDL was higher in non-smokers when compared to that of smokers and were statistically significant.  },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Begum_2021,

title = {Insight of medical students on online teaching during COVID-19 pandemic},

author = {Vaseemunnisa Begum and Neeraj Sadiq and Ghulam Subhani and Syeda Asma Gulnaaz and Mohammed Mohsin and Nageswari Devi},

url = {https://www.ijpp.org.in/journal-article-file/14660},

doi = {10.18231/j.ijpp.2021.033},

issn = {2393-9079},

year  = {2021},

date = {2021-09-04},

urldate = {2021-09-04},

journal = {Indian Journal of Pharmacy and Pharmacology},

volume = {8},

issue = {3},

pages = {195-199},

abstract = {Background: The Global disease (COVID-19 pandemic) has impacted our lives in various ways. Online teaching is the strange routine for studying platforms to continue with the process of educating students, Online classes have become a key component in the continuity of education. Aims: 1. This study aims to rank the usefulness of online teaching compared to classroom conventional teaching 2. Socioeconomic parameters related to online teaching in a medical college. Study Design: The study is a cross-sectional study done on medical students. A questionnaire was prepared listing the various ways in which they discern online teaching trying to cope up during the pandemic. Materials and Methods: After the institutional Ethics committee clearance, online cross-sectional study was done on the medical students where from the 2 and 3 year. This online survey was done between 10May 2021- 10 June 2021, A total number of 211 students participated out of 250, after completion of 18 months of online classes. A Set of 15 self -designed questionnaire based on 5 point Likert scale was given to the students to rank the effectiveness through online class usefulness levels and satisfaction levels on various parameters. Students were also asked about the demographic factors. Statistical Analysis: The data was analyzed using software SPSS software. Results: The study results shows that online classes is less helpful in five parameters and equally helpful in five parameters but was not at all superior to conventional methods, we can come to the interpretation that students think that classroom teaching cannot be replaced by online teaching. Conclusions: We can conclude that online studies can only be a supplement and cannot be an alternate for the established order of learning.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2021,

title = {A questionnaire based study-assessment of knowledge, attitude and practice of pharmacovigilance among health care professionals-pre and post educational intervention},

author = {Husna Fatima and Ghulam Subhani and Mohammed Mohsin and Nageswari Devi},

url = {https://www.ijbcp.com/index.php/ijbcp/article/view/4661/3201},

doi = {10.18203/2319-2003.ijbcp20212070 },

issn = {2279-0780},

year  = {2021},

date = {2021-05-25},

urldate = {2021-05-25},

journal = {International Journal of Basic & Clinical Pharmacology},

volume = {10},

issue = {6},

pages = {638-642},

abstract = {Background:Pharmacovigilance (PV) is an important tool in generating adverse drug reaction (ADR) data. However, the practice of PVis still very low among health care professionals due to lack of knowledge and awareness. This study was conducted to assess the level ofknowledge, awareness and practice of PVamong health care professionals and to assess subsequent change in these after PVtraining session.Methods:A cross sectional questionnaire based study  was  conducted among health care professionals of a tertiary health care and teaching institute. Participants were given a questionnaire. They completed it before and after undergoing training programme in PV. Impact of effectiveness of educational intervention (continuing  medical education CME (pharmacovigilance workshop) was evaluated by paired t-test. Results:Out of 110 participants, 96 participants completely filled the questionnaire before and after the educational intervention(CME). CME on PVwas found to increase knowledge and positive attitudes towards various aspects of PV.Conclusions:Training programme on PV will help increase the knowledge as well as awareness about principles and techniques  of PVand  improve the rate of spontaneous ADR reporting. Organising frequent CME programmes and workshops will increase the credibility of health care in the country.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sadiq_2021,

title = {Antidiabetic effect of nigella sativa compared with metformin on blood glucose levels in streptozotocin induced diabetic albino wistar rats},

author = {Neeraj Sadiq and Ghulam Subhani and Syeda Ayesha Fatima and Mohammed Nadeem and Shaima Zafer and Mohammed Mohsin},

url = {https://www.ijbcp.com/index.php/ijbcp/article/view/4579/3149},

doi = {10.18203/2319-2003.ijbcp20211016 },

issn = {2279-0780},

year  = {2021},

date = {2021-03-22},

urldate = {2021-03-22},

journal = {International Journal of Basic & Clinical Pharmacology},

volume = {10},

issue = {4},

pages = {361-367},

abstract = {Background: Antidiabetic drugs are many but all of them have adverse effects ranging from simple side effects to serious side effects like hypoglycemic coma. We need alternative drugs which will not only lower blood sugar level but have fewer side effects. One such daily use ingredient in our food is Nigella sativa (kalonji) which has many properties. Methods: This was an objective study in an experimental animal. We divided albino wistar rats into six groups each group with six rats. Diabetes was induced using drug streptozotocin. Three doses of Nigella sativa 0.5 ml, 1 ml, 1.5 ml orally per rat were used. Metformin (100 mg/kg body weight) was used as standard drug. Blood sugar was estimated using glucometer on day 0 (starting day of treatment), day 5, day 10, day 20, day 40. The effect of Nigella sativa was compared with metformin group using the Anova test. Statistical analysis was done using SPSS software version 20. Results: Nigella sativa (NS) produced significant hypoglycemic effect. NS in the dose of 0.5 ml, 1 ml and 1.5 ml produced significant reduction in blood glucose in comparison to day 0. Metformin also (100 mg/kg body weight) produced significant reduction in blood glucose on day 20 and day 40. Comparison of hypoglycemic effect of Nigella sativa is not significantly different on day 10 (1 ml) and day 20 (1.5 ml) in comparison to Metformin (100 mg/kg body weight). Histopathological examination showed that there was partial regeneration of beta islet cells of pancreas by 1.5 ml of Nigella sativa which were damaged due to streptozotocin treatment. Conclusions: Alternative method of treatment for diabetes is very much needed and the study shows the use of the spice (Nigella sativa) daily can lower the blood sugar levels and can serve as an alternative treatment of diabetes mellitus.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Syeda_2020,

title = {Experimental evaluation of antidiabetic effect of punica granatum peel extract against streptozotocin induced diabetes in albino rats},

author = {Shakira Fathima Syeda and Mohammed Mohsin},

url = {https://www.ijpbs.net/abstract.php?article=NjkxNw==},

doi = {10.22376/ijpbs.2020.11.4},

issn = {0975-6299},

year  = {2020},

date = {2020-12-01},

urldate = {2020-12-01},

journal = {International Journal of Pharma and Bio Sciences},

volume = {11},

issue = {4},

pages = {115-121},

abstract = {Diabetes mellitus is a disease characterised by derangement in carbohydrate, protein and fat metabolism which is caused by the complete or relative insufficiency of insulin secretions. Plants and their bioactive constituents are used for the treatment of diabetes mellitus throughout the world; especially in countries where access to the conventional treatment of diabetes mellitus is inadequate. The present study was undertaken to investigate the anti-diabetic effect of Punica granatum ethanolic peel extract in STZ induced diabetic rat. STZ was used to induce diabetes in albino rats weighing 150-250 grams. The fasted diabetic rats were divided in to 6 groups of 6 animals each. Group I Normal control group received distilled water 5 ml/kg body weight orally daily, Group II were treated with STZ 50mg/kg body weight induced diabetic rats were served as diabetic control group and were treated with distilled water orally daily until diabetes occur, Group III i.e STZ induced diabetic rats were served as standard group and were treated with Glibenclamide at a dose of 0.5 mg/kg body weight orally daily. Group IV & Group V Punica granatum ethanolic peel extract was administered with 100mg/kg and 200mg/kg dose orally. This study was conducted over a period of 15 days with oral administration of drugs and the plant extract which was started on the 6th day of STZ treatment. The fasting blood glucose levels were determined on day 0, 5th, 10th, and 15th day by using glucometer. The maximum reduction in Blood Glucose level was observed at a dose of 200mg/kg body weight. Data were statistically analyzed by Student “t” Test.  P<0.001 was considered as highly significant.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Syeda_2020,

title = {Evaluations of antidepressant activity of punica granatum peel extract in albino mice},

author = {Shakira Fathima Syeda and Sam Pavan Kumar G. and Mohammed Mohsin},

url = {https://www.ijbcp.com/index.php/ijbcp/article/view/3887/2804},

doi = {10.18203/2319-2003.ijbcp20200720 },

issn = {2279-0780},

year  = {2020},

date = {2020-02-25},

urldate = {2020-02-25},

journal = {International Journal of Basic & Clinical Pharmacology},

volume = {9},

issue = {3},

pages = {449-453},

abstract = {Background: Depression is the most common disorder of mental illnesses and affects excess of 10-15% of population. According to the WHO reports, more than 350 million persons suffer from depression all over the world. The aim of present study is to evaluate anti-depressant activity of Punica granatum peel extract (PgPE) in albino mice. Methods: Male albino mice (20-30 g) were used. Animals were divided into 5 groups with 6 animals in each which were subjected to forced swim test. Group 1 is control, group 2 received (standard) imipramine 10 mg/kg, p.o, group 3 (T1) PgPE 50 mg/kg, p.o, group 4 (T2) PgPE 100 mg/kg, p.o, group 5 (T3) PgPE 200 mg/kg, at first animals were forced to swim for 15 min (trained), and the study was performed after 24 hrs. All the animals were treated with individual drug 60 min prior to study, animals were forced to swim for 6 min and the duration of immobility was recorded. The mouse was considered immobile when it floats motionlessly or made only those moments necessary to keep its head above the water surface. The total duration of immobility of each mouse was recorded after the test in each group. Results: The duration of immobility is significantly reduced at PgPE 200 mg/kg and results were analysed by one way analysis of variance (ANOVA). Conclusions: PgPE 200 mg/kg significantly (p<0.05) decreases the duration of immobility in mice.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Syeda_2019,

title = {Evaluations of antidepressant activity of nerium oleander flower extract in albino mice},

author = {Shakira Fathima Syeda and Pushpalatha C. and Mohammed Mohsin},

url = {https://www.ijsr.net/archive/v8i7/ART20199502.pdf},

issn = {2319-7064},

year  = {2019},

date = {2019-07-01},

urldate = {2019-07-01},

journal = {International Journal of Science and Research},

volume = {8},

issue = {7},

pages = {979-980},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Naveed_2018,

title = {N-acetylcysteine in a treatment of COPD},

author = {M. Aleemuddin Naveed and Raheem Fatima and Mohammed Mohsin and Ashfaq Hasan},

url = {https://www.ijirm.org/journal-article-file/7457},

doi = {10.18231/2581-4222.2018.0035},

issn = {2581-4214},

year  = {2018},

date = {2018-09-01},

urldate = {2018-09-01},

journal = {IP Indian Journal of Immunology and Respiratory Medicine},

volume = {3},

issue = {3},

pages = {137-146},

abstract = {Introduction: In COPD excess expectoration secondary to tracheobronchial secretions contributes to symptoms, airflow obstruction and is diagnostic criterion. It also causes increased mortality, risk of hospitalizations and accelerated decline in FEV1. N-acetylcysteine (NAC) helps in liquefying mucus and DNA (via disruption of disulfide bonds) and has antioxidant effects. Aims: Evaluate add-on effect of NAC on clinical-physiological parameters in COPD patients treated according to GOLD guidelines. Material and Methods: Single labeled, randomized, parallel group prospective Observational study. In 120 stable COPD patients Modified medical research council (MMRC) dyspnoea score, COPD Assessment test (CAT score), number of exacerbations and hospitalizations in the last year were recorded and were randomized into 2 groups of 60 each. Group A

received NAC 600mg twice daily along with standard treatment. Group B received standard treatment only. Mean and Standard Deviation was compared between groups using unpaired t-test. After 1 year, changes in above parameters were reassessed. Statistical Analysis: Unpaired t-test and chi square test were used. Statistical significance was set at <0.05 level. Results: MMRC score reduced from 3.37 study group) to 2.91, difference being -0.46, and in control from 3.37 to 1.18, difference of -0.22 and p value of p<.05. CAT score reduced more in test group (-4.4) than control group (-3.1), p=.02. Out of 40 exacerbations, 14 (35%) occurred in test and 26 (65%) in control group, reduction of 30% and p=0.01. Out of 28 hospitalizations 10 (36%) test group 18 (64%) control group. i.e. a reduction of 28% and p=0.06. Conclusions: Use of N-Acetyl Cysteine, 600mg twice daily along with standard treatment can bring clinically significant change in CAT Score and frequency of exacerbations but not in MMRC score and hospitalizations. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Syeda_2018,

title = {Experimental evaluation of anti inflammatory activity of punica granatum peel extract in albino rats},

author = {Shakira Fathima Syeda and Sam Pavan Kumar G. and Pushpalatha C. and Mohammed Mohsin},

url = {https://caims.in/assets/journal/2018/CAIMS_Journal_Jan_-_Jun_2018___05.pdf},

issn = {2278-5310 },

year  = {2018},

date = {2018-06-01},

urldate = {2018-06-01},

journal = {Journal of Chalmeda Anand Rao Institute of Medical Sciences},

volume = {15},

issue = {1},

pages = {117-122},

abstract = {Aim: The aim of present study is to evaluate Anti-inflammatory activity of Punica granatum. L peel extract in albino rats. Materials and Methods: Albino rats of either sex weighing between 150 grams to 200 grams were divided into five groups of six animals (30) i.e control(C), standard (S), Test-1 (T1), Test-2(T2) & Test-3 (T3). Different groups of rats had received dose calculated according to body weight. C group had received 5ml/kg of 2% gum Acacia suspension orally. Diclofenac suspension in 2% gum Acacia was given to the standard (S) group in the dose of 5mg/kilogram body weight, orally. T1 group had received 100mg/kg, T2 group had received 200mg/kg & T3 group had received 400mg/kg body weight, orally. After half an hour of drug administration, sub-plantar injection of Carrageenin was administered by a tuberculin syringe into the right hind paw of all rats. Right hind paw was marked by a marker pen, at the level of lateral malleolous and the paw was dipped into the mercury of the plethysmograph and paw volume was measured by mercury displacement method immediately, and after 1 hour, 2 hour, 3 hours of the sub-plantar injection of carrageenin. The difference of paw volume recorded at the beginning of the experiment and at the end of 1 hour, 2hour & 3 hour of carrageenin administration. Percentage inhibition of inflammation was calculated by formula % inhibition = Vc-Vt/Vc X 100. Result : Result will be recorded and results will be analyzed by appropriate statistical methods. Conclusion: The present study revealed that Punica granatum L peel extract show anti-

inflammatory activity in albino wistar rats. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zafer_2018,

title = {A study of serious adverse drug reactions with antiepileptic drugs: a pharmacovigilance study},

author = {Shaima Zafer and Mohammed Abid Ali and Ghulam Subhani and T. Ushashree

},

url = {https://www.ijbcp.com/index.php/ijbcp/article/view/2441/1914},

doi = {10.18203/2319-2003.ijbcp20181636},

issn = {2279-0780},

year  = {2018},

date = {2018-04-23},

urldate = {2018-04-23},

journal = {International Journal of Basic & Clinical Pharmacology},

volume = {7},

issue = {5},

pages = {922-925},

abstract = {Background: Approximately 50 million people worldwide have epilepsy, making it one of the most common neurological diseases globally. There are currently more than 25 drugs in the market for the treatment of epilepsy, many of which have similar efficacy but differ in their tolerability profile. Besides unmatched beneficial potential of antiepileptic drugs, it is associated with many adverse reactions too. This study aims to identify the serious adverse reactions caused by prescribed antiepileptics, reported at the pharmacovigilance centre of government tertiary care centre. Methods: This is a retrospective, pharmacovigilance study of the antiepileptic drugs adverse reactions reported over a period of 1 year at a tertiary care centre. Results: A total of 120 ADRs of antiepileptic drugs were reported and collected at the pharmacovigilance centre. According to the WHO-ART system organ classification of ADRs, 78% of ADRs belonged to skin and appendages disorder. Based on the modified Hartwig and Siegel scale of severity, 60.8% ADRs were mild, 18.5% were moderate and 20.8 % were severe ADRs. The severe ADRs included: Steven-Johnson syndrome, Toxic epidermal necrolysis, Erythroderma, DRESS syndrome and Acute pancreatitis. Phenytoin has been found to be the antiepileptic drug causing the most number of severe ADRs amongst the prescribed antiepileptics. According to the modified Schumock and Thornton criteria most of the severe ADRs were not preventable. Conclusions: This study analyses the ADRs associated with antiepileptics reported at the pharmacovigilance centre. 20.8% ADRS were severe, this indicates that the epileptic patients should be closely monitored for ADRs, to avoid clinically significant harmful consequences. The awareness of ADRs would help physicians to identify patients with greater risk of ADRs and therefore, might benefit from ADRs monitoring and reporting programmes.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zafer_2018b,

title = {E-learning in medical education-a cross sectional study in a medical college},

author = {Shaima Zafer and Ghulam Subhani and Raheem Fatima and Humaira Fatima},

url = {http://jmscr.igmpublication.org/v6-i3/100%20jmscr.pdf},

doi = {10.18535/jmscr/v6i3.100},

issn = {2347-176X},

year  = {2018},

date = {2018-03-01},

urldate = {2018-03-01},

journal = {Journal of Medical Science and Clinical Research},

volume = {6},

issue = {3},

pages = {604-607},

abstract = {Introduction: Medical education is acquiring knowledge and skills for ensuring the quality of health protection .Qualitative and quantitative studies of collaborative learning in medicine have shown higher levels of learner satisfaction, self awareness, improvement in knowledge and understanding of concepts. E-learning when combined effectively with quality professional teaching may achieve the goal of complete education. Methodology: A Prospective, cross-sectional, structured questionnaire based study was conducted among 300 medical students in a medical college. Result: A questionnaire study was conducted among the students of medical sciences. 76% students had access to internet.70% use internet for e-learning. 68% find e-learning helpful.56% watch educational videos, 42% refer to online books, 74 % are Wikipedia users. 62 % find online teaching session interesting.68% find e-leaning better then didactic teaching. 66% preferred e-learning in combination with classroom lectures where as 20 % preferred classroom lectures and 14 % preferred e-learning

alone. 78% want e-learning to be applied in education. Conclusion: E-learning and technology are creating the groundwork for a revolution in education. E-learning therefore should be incorporated and explored further in the medical education system of India. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Farheen_2016,

title = {Prescription pattern of non-steroidal anti-inflammatory drugs in patients with acute musculoskeletal pain},

author = {Humaira Farheen and Ghulam Subhani and Mohammed Mohsin},

url = {https://www.ijbcp.com/index.php/ijbcp/article/view/41/39},

doi = {10.18203/2319-2003.ijbcp20164113},

issn = {2279-0780},

year  = {2016},

date = {2016-12-21},

urldate = {2016-12-21},

journal = {International Journal of Basic and Clinical Pharmacology},

volume = {5},

issue = {6},

pages = {2504-2509},

abstract = {Background: Without the knowledge on how drugs are being prescribed and used, it is difficult to initiate a discussion on rational drug use and to suggest measures to change prescribing habits for the better information on  the past performance of prescribers is linchpin of any auditing system. The objective of the study was to assess  the NSAIDs prescription pattern in patients with MS pain. Methods:Prospective study of prescriptions of 306 patients  with MS pain presenting in orthopedic outpatient department (OPD) of Owaisi Health and Research Centre during the period of January 2014 to August 2015. Patient particulars, history and clinical findings were obtained using the   study proforma. Data collected was analyzed by frequency, and percentage. Results:Overall frequency of NSAIDs prescription in this study was 96%. Diclofenac (70.7%) was the commonest NSAID prescribed. Selective COX-2 inhibitors were not prescribed. Combination of paracetamol and tramadol (77%) was the commonest FDC prescribed among  the 92 FDC prescriptions. High frequency of GPAs co-prescription (94%) was noted. Of 7 different NSAIDs prescribed, 2 drug (diclofenac, and paracetamol) falls within DU90% segment-mainly constituted by non-selective NSAIDs. Conclusions:Overall, the prescription pattern was in accordance with standard guidelines, as suggested by the fact  that the DU90%, segment was constituted by only few drugs.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}