@article{Zoheb_2024,

title = {High blood pressure, hyperlipidemia, type 2 diabetes with prior history of atrial fibrilation caused stroke},

author = {Mohammed Zoheb and Deeba Rana and Shaikh Mahmood},

url = {https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/article/high-blood-pressure-hyperlipidemia-type2-diabetes-with-prior-history-of-arterial-fibrilation-caused-stroke/NTUzMDY=/?is=1&b1=&k=},

issn = {2277-8179},

year  = {2024},

date = {2024-04-01},

journal = {International Journal of Scientific Research},

volume = {13},

issue = {4},

pages = {1-2},

abstract = {The stroke cases are on rise, to know its causes, symptoms & treatment patients have to be studied in detail and get the appropriate result. Stroke is a serious medical condition that can sometimes be deadly. Stroke cases are emerging at a startling rate at the moment. People with specific medical problems are more susceptible to stroke, even though it may affect anybody. A stroke or brain stroke can be fatal and result from inadequate blood supply to a portion of the brain, according to the Cleveland Clinic. The most common causes of this are cerebral hemorrhage or arterial obstruction. If insufficient blood flow occurs, oxygen-starved brain cells begin to die. A stroke may happen to anybody, at any age, although certain people are more susceptible than others. Furthermore, beyond the age of 65, the danger rises. Strokes occur commonly in either sex. Strokes are the second largest cause of mortality worldwide. Not only that, but stroke is a leading global cause of disability. The following are a few examples of stroke symptoms paralysis on one sides peaking difficulties or loss of speech distorted or double vision (diplopia) inability to coordinate light headedness

and vomiting stiff neck personality shift agitation or confusion seizure loss of memory headache loss of consciousness the blood clotting disorder atherosclerosis Heart abnormality (ventricular or atrial septal defect) microvascular ischemia elevated blood pressure tumors of the brain (including cancer)Heart abnormality (ventricular or atrial septal defect) microvascular ischemia elevated blood pressure tumors of the brain (including cancer) etc.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hyder_2024,

title = {Effect of smartphone usage during night time on sleep patterns of young adults: A cross-sectional observational study},

author = {Safa Hyder and Sudhir Shankar Mane and Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin},

url = {https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2024&month=April&volume=18&issue=4&page=CC01&id=19291},

doi = {10.7860/jcdr/2024/66874.19291},

issn = {0973-709X},

year  = {2024},

date = {2024-04-01},

urldate = {2024-01-01},

journal = {Journal of Clinical and Diagnostic Research},

volume = {18},

issue = {4},

pages = {CC01-CC06},

publisher = {JCDR Research and Publications},

abstract = {Introduction: Excessive smartphone usage among adolescents and young adults has been consistently linked to poor sleep. Moreover, smartphone overuse has been associated with daytime tiredness, longer sleeps latency, and reduced sleep duration. The significance of addressing poor sleep among adolescents and young adults is underscored by recent research linking it to adverse physical and psychological health outcomes, such as mood disturbances, impaired cognitive function, and increased risk incidence of hypertension and diabetes.

Aim: To evaluate the effects of smartphone usage on sleep quality among individuals using Pittsburgh Sleep Quality Index (PSQI) and hypnogram data.

Materials and Methods: In this cross-sectional observational study, sleep patterns were assessed using the PSQI questionnaire and Prime Nap sleep tracker app (version 1.1.4). The study was conducted by Deccan College of Medical Sciences, Hyderabad, Telangana, India. The data was collected in the form of a hypnogram and the study was conducted in the participants’ homes (under domicile conditions) in the city of Hyderabad, Telangana, India from March 2020 to April 2020. A total of 60 participants (both male and female) in the age group of 15-25 years were recruited and divided into two groups: one comprising 30 individuals with regular prolonged exposure to smartphone screens at night, and the other consisting of 30 individuals who experienced minimal or no smartphone exposure once they prepared to sleep. Descriptive statistics were applied to the collected data using Microsoft Excel and IBM Statistical Package for Social Sciences (SPSS) for Windows version 25.0.

Results: Adding up the average scores of the seven factors gives a global PSQI score from 0 to 21, with 0-4 indicating good sleep and 5-21 indicating poor sleep. Among those who used smartphones regularly at night time, 20 participants (66.67%) had PSQI score >5 and poor sleep quality, 24 participants (80%) had prolonged sleep latency, 18 participants (60%) had poor sleep duration, 27 participants (90%) had sleep disturbances, and 22 participants (73.33%) had increased daytime dysfunction. Hypnogram abnormalities were seen in >15 participants (50%) of subjects.

Conclusion: The prevalence of smartphone addiction is widely acknowledged in the medical literature, highlighting the need for its assessment, especially among adolescents and young adults. The study reveals that poor sleeping habits among participants were attributable either to a lack of awareness or neglect. By recognising the importance of adequate sleep, improvement in the quality of daily activities can be made by reducing daily screen time, consequently alleviating both physical and mental stress. Furthermore, the findings have implications for individuals whose work involves prolonged exposure to computer screens, especially during night time.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Unnisa_2023,

title = {Effect of physical activity on glycated hemoglobin [HbA1c] in non-diabetic individuals},

author = {Arshiya Unnisa and Farah Bahmed and Farisa Khatoon and Mehnaaz Sameera Arifuddin and Nazia Uzma},

url = {https://journals.lww.com/jdyu/fulltext/2023/12030/effect_of_physical_activity_on_glycated_hemoglobin.15.aspx},

doi = {10.4103/jdrysruhs.jdrysruhs_24_22},

issn = {5555-6666},

year  = {2023},

date = {2023-12-27},

journal = {Journal of Dr. YSR University of Health Sciences},

volume = {12},

issue = {3},

pages = {285-290},

abstract = {Introduction: Physical inactivity is a rapidly evolving public health issue that contributes to a wide range of chronic diseases and health consequences, including obesity, diabetes, and cancer. In addition to improving a patient’s overall health, increased physical activity has been demonstrated to be beneficial in the management of chronic conditions. The purpose of this research is to discover if there is a link between physical activity intensity and HbA1c levels in non-diabetic adults and, if so, which type of physical activity has the most impact on glycemic control.

Material and Methods: There were 90 healthy non-diabetic individuals in the study. The International Physical Activity Questionnaire (IPAQ) score was calculated after each subject’s physical activity questionnaire was evaluated. Based on their IPAQ scores, the participants were split into three groups: low, moderate, and vigorous physical activity. A 3 mL blood sample was taken in a vacutainer to determine HbA1c levels. The data was produced in Microsoft Excel and analyzed using the statistical application SPSS 17.0.

Result: HbA1c values were statistically significant in the moderate-physical-activity group, while IPAQ showed a statistical difference between males and females in the vigorous-physical-activity group. In all three groups, IPAQ scores were significantly different but not in HbA1c levels. The HbA1c and IPAQ scores had a modest negative connection. The difference between males and females in our study was statistically insignificant. The body mass index (BMI) and HbA1c, as well as BMI and IPAQ, were found to have a positive linkage.

Conclusion: Physical activity, particularly moderate-to-vigorous activity, has a bigger influence on non-diabetic people’s glycemic regulation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2023d,

title = {Morphometric study of human brain ventricles by magnetic resonance imaging in Indian population: a retrospective study},

author = {Zafar Sultana Abdul Saleem and Farah Bahmed and Syeda Sadia Sameera and Sravan Kumar Marupaka and Habib Khan Gulab Khan Pathan},

url = {https://journals.lww.com/jdyu/fulltext/2023/12020/morphometric_study_of_human_brain_ventricles_by.15.aspx},

doi = {10.4103/jdrntruhs.jdrntruhs_210_22},

issn = {5555-6666},

year  = {2023},

date = {2023-12-01},

urldate = {2023-12-01},

journal = {Journal of Dr. YSR University of Health Sciences},

volume = {12},

issue = {2},

pages = {171-177},

abstract = {Introduction: Ventricular parameters are used to study hydrocephalus, schizophrenia, tumors, trauma, Alzheimers disease, gender, aging and atrophy associated with many neurological diseases as stroke and dementia, to assess loss of brain parenchyma. Normal reference values of brain ventricles obtained by MRI are necessary to create baseline data for interpreting pathological changes, planning surgery and determining presence and progress of some neurological disorders. Materials and Method: This is a retrospective, cross sectional and non-interventional study. we have studied 100 brain MRI digital images. Following parameters have been studied frontal horn width [FHW], transverse internal diameter of skull[TIDS-F] at same level, frontal horn ratio[FHR], frontal horn length on both sides [FHLR & FHLL], total length of lateral ventricle on both sides [LVLR & LVLL], posterior horn width [PHW], transverse internal diameter of skull at same level [TIDS-P], fourth ventricle width [FVW] and fourth ventricle anteroposterior distance [FVAP]. SPSS. version. 21 was used for statistical analysis. Results: There were 54 females and 46 males between age 20 years to above 60 years. Frontal horn width, posterior horn width and total inner diameter of skull at frontal and posterior level has shown significant gender differences with P value as 0.0034,0.0004,0.00013 and 0.0004 respectively. Frontal horn ratio, total length of right and left lateral ventricles and total inner diameter of skull has shown significant increase with age. Conclusion: The normal reference values of ventricles obtained from MRI are necessary to form baseline data, for interpreting pathological changes and planning surgeries.volumetric measurements will provide more information than linear measurements.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2023,

title = {Multisystem inflammatory syndrome in children (MIS-C) of Asian countries: a mini-literature review on its clinical characteristics and outcomes},

author = {Mehnaaz Sameera Arifuddin and Mohammed Abdul Hannan Hazari},

url = {https://esmed.org/MRA/mra/article/view/4070},

doi = {10.18103/mra.v11i7.2.4070},

issn = {2375-1924},

year  = {2023},

date = {2023-07-29},

urldate = {2023-07-29},

journal = {Medical Research Archives},

volume = {11},

issue = {7.2},

pages = {1-7},

abstract = {COVID-19 pandemic though has reached endemic levels in most of the countries, it has left an indelible mark on the healthcare systems across the world. One of the emerging challenges faced by physicians and researchers all around the world is the increased incidence of Multisystem inflammatory syndrome in children (MIS-C). Most of the research work conducted till date focusses on the pathophysiology, management and treatment of this syndrome. Multisystem inflammatory syndrome in children has been found to be a consequence of hyperactive immune system resulting from cytokine activation and release of immune complexes subsequent to COVID-19 infection. This condition is also associated with multisystem dysfunction which if not diagnosed early and not treated promptly, could result in an increased mortality among children. Most of the cases have been reported from European and American countries, but not many from Asia. 

This literature review provides for plausible reasons as to why the incidence of multisystem inflammatory syndrome in children has been less in Asian countries compared to the rest of the world. It also gives insights into the treatment protocols for multisystem inflammatory syndrome in children followed by hospitals in these countries and also highlights how different MIS-C is from Kawasaki disease in terms of clinical presentation since both these conditions share a common disease spectrum. This review also lists out the clinical features and treatment followed in such patients belonging to Asian countries.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2023,

title = {Effect of COVID-19 infection on mental health of medical students},

author = {Ariyan Khan and Mustafa Kagalwala and Minhajzafar Nasirabadi and Mazher Ali and Mehnaaz Sameera Arifuddin},

url = {https://www.tjima.org/journal/index.php/tjima/article/view/110},

doi = {10.52314/tjima.2023.v3i1.110},

year  = {2023},

date = {2023-06-28},

journal = {Telangana Journal of IMA},

volume = {3},

issue = {1},

pages = {13–21},

abstract = {Background: Stressful environment in medical school often has a negative effect on students’ psychosocial well‐being and COVID-19 has a further additive effect on it. The COVID-19 pandemic is found to affect the mental health of the population. Undergraduate medical students are especially prone to mental health disorders and hence could be more vulnerable to the impact of the pandemic. An in‐depth understanding of how medical students experience psychological distress and coping is necessary for prospective students. 

Aim and Objective: To determine the effect of COVID-19 on mental health of medical students. 

Methods: A web-based cross-sectional study was carried out on 299 undergraduate medical students in the medical colleges of Telangana and Andhra Pradesh, India. They were divided into 4 groups based on whether the participants, their family members, both or none of them were affected with COVID-19 infection. The questionnaires provided to the participants in this study consisted of three components – (i) the demographic information that required participants to provide their gender, age and year of study (ii) COVID-19 related questionnaire and (iii) Depression, Anxiety, and Stress Scale‐42 (DASS-42) items to measure the levels of psychological distress among participants. Chi square statistical test and One-way analysis of variance (ANOVA) were the statistical tools used in this study.

Results: It was observed that depression (χ=9.839, p=0.043) was found to be significant in participants who were not affected with COVID-19 infection. Statistically significant differences were observed in participants’ depression (χ=11.976, p=0.018) and stress (χ=9.839, p=0.043) levels whose family members were affected with COVID-19. One way ANOVA showed that anxiety levels (F(3,295)=4.267, p=0.006) was significantly higher when both participants and their family members (group 3) were affected with COVID-19 infection.

Conclusion: This study has shown that COVID-19 pandemic and subsequent lockdowns affected the mental health of young population.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2021b,

title = {Comparison of medial longitudinal arches of the foot by radiographic method in users and nonusers of high-heeled footwear among young women},

author = {Saimah Naseer and Ravindra Prakash Babu and Panjala Ashok and Mehnaaz Sameera Arifuddin and Hunaina Manfusa and Ephraim Vikram Rao},

url = {https://journals.lww.com/joai/Fulltext/2021/70040/Comparison_of_Medial_Longitudinal_Arches_of_the.7.aspx},

doi = {10.4103/jasi.jasi_202_20},

issn = {2352-3050},

year  = {2021},

date = {2021-12-31},

urldate = {2021-12-31},

journal = {Journal of the Anatomical Society of India},

volume = {70},

issue = {4},

pages = {226-232},

publisher = {Wolters Kluwer - Medknow},

abstract = {Introduction: The arches of the foot help in transmission of the body weight and permit adjustments on uneven surfaces. Prolonged use of high heels causes elevation or collapse of these arches by stress and strain over the weight-bearing bones, and also causes damage to the underlying soft tissues and ligaments. The aim of this study was to document the presence of any changes in medial longitudinal arches in young women using high heels through radiographic method taking into account body mass index, height of heels, and the type of shoes worn and to document lower back pain and foot pain. 

Material and Methods: An observational study between 40 high-heel wearers and 40 flat wearers was done. Lateral radiographs of both feet were taken in weight-bearing position with medial border of the foot touching the cassette. Lateral talocalcaneal angle, lateral talar-first metatarsal angle, angle of longitudinal arch, and calcaneal pitch were measured by a protractor and goniometer. A questionnaire documented complaints of back pain and foot pain. 

Results: Independent sample t-test showed a statistically significant difference in left lateral talar-first metatarsal angle between two groups. Pearson's correlation showed a negative correlation between left lateral talocalcaneal angle and low back pain, and a positive correlation between right lateral talar-first metatarsal angle and low back pain. 

Discussion and Conclusion: Frequent and prolonged use of high-heeled footwear can result in damage to the foot architecture leading to foot and back pain. Thus, keeping the high heels reserved for occasional use is the best choice.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2021,

title = {Emergence of MIS-C in COVID-19 pandemic},

author = {Mehnaaz Sameera Arifuddin},

url = {https://amphysiol.com/index.php/amp/article/view/v4i3.14465},

doi = {10.23921/amp.2020v4i3.14465},

issn = {2456-8422},

year  = {2021},

date = {2021-01-15},

urldate = {2021-01-15},

journal = {Annals of Medical Physiology},

volume = {4},

issue = {3},

pages = {22-23},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2020,

title = {Effect of tea and coffee consumption on the blood pressure, pulse wave velocity and aortic pressures in young healthy individuals},

author = {Farah Fatima and Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin and Syed Abdul Tahreem},

url = {https://amphysiol.com/index.php/amp/article/view/v4i1.94611},

doi = {10.23921/amp.2020v4i1.94611},

issn = {2456-8422},

year  = {2020},

date = {2020-06-30},

urldate = {2020-06-30},

journal = {Annals of Medical Physiology},

volume = {4},

issue = {1},

pages = {3-11},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Caffeine present in tea and coffee, the most commonly used beverages, has been implicated to have long term effects on cardiovascular system. The aim of this study was to document the acute and chronic effects of tea and coffee consumption on blood pressure, pulse wave velocity and aortic pressures in young, healthy individuals. This observational study was conducted on 86 healthy MBBS student volunteers of both genders between the age group of 18-27 years. Cardiovascular parameters (heart rate, peripheral blood pressure, central blood pressure, pulse wave velocity, augmentation pressure) were measured using PeriScope™. Participants were divided into 3 groups based on their history of consuming tea/coffee/both/none. Data collected was analyzed using SPSS 17.0. ANOVA or Welsh test of equality of means was used for knowing the differences for scale variables. Paired sample t test was used to know the acute effect of coffee consumption among group 1 participants in a before-after design. In regular tea consumers, the bilateral brachial SBP, DBP and MAP were significantly higher than individuals who did not consume tea regularly; similar results in these parameters were also observed in regular coffee drinkers. However the lower limb arterial parameters were not markedly differently in tea/coffee group compared to non-drinkers. In both tea and coffee group, AoSP and AoDP were significantly higher than non-drinkers. Additionally, coffee drinking has acute stimulatory effects on CVS as evident by increase in peripheral and central vascular parameters.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2020,

title = {SARS-CoV-2 and ACE2 nexus},

author = {Mehnaaz Sameera Arifuddin},

url = {https://amphysiol.com/index.php/amp/article/view/v4i1.120578},

doi = {10.23921/amp.2020v4i1.120578},

issn = {2456-8422},

year  = {2020},

date = {2020-06-30},

urldate = {2020-06-30},

journal = {Annals of Medical Physiology},

volume = {4},

issue = {1},

pages = {1-2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sadaf_2020,

title = {Correlation of systolic and diastolic time intervals with demographic and anthropometric parameters in young adults},

author = {Sadiqua Sadaf and Mehnaaz Sameera Arifuddin and Mohammed Ziya Rahman and Mohammed Abdul Hannan Hazari and Syeda Bushra Quadri},

url = {https://www.j-pcs.org/article.asp?issn=2395-5414;year=2020;volume=6;issue=1;spage=23;epage=32;aulast=Sadaf;t=6},

doi = {10.4103/jpcs.jpcs_56_19},

issn = {2395-5414},

year  = {2020},

date = {2020-04-17},

urldate = {2020-04-17},

journal = {Journal of the Practice of Cardiovascular Sciences},

volume = {6},

issue = {1},

pages = {23-32},

publisher = {Wolters Kluwer - Medknow},

abstract = {Context: Dimensions of vasculature may vary with height, weight, and build of the individual. This may, in turn, influence the time intervals during cardiac cycle. Aims: The aim of this study was to correlate the systolic and diastolic time (DT) intervals (preejection period [PEP], ejection time [ET], upstroke time [UT], DT, pulse duration [PD], and ejection slope [ES]) of pulse waves recorded from all four limbs in relation to age, gender, weight, height, heart rate, and blood pressure and to compare these cardiac time intervals between individuals with or without parental history of hypertension. Settings and Design: Ninety-eight healthy MBBS students in the age group of 19–21 years were included. Subjects and Methods: Students' history and demographic data were noted. Anthropometric measurements were recorded. The measurement of peripheral arterial pressures (in all four limbs) and determination of cardiac intervals (PEP, ET, UT, DT, PD, and ES) was done by PeriScope™. Statistical Analysis Used: Data were analyzed using SPSS version 17.0. Results: Independent sample t-test showed statistically significant differences between genders with weight, height, waist circumference, and waist–hip ratio. Statistically significant differences existed between right arm systolic blood pressure, left arm systolic blood pressure, and left arm pulse pressure among males and females. Significant differences among males and females were observed in some of the cardiac time intervals. Mean arterial blood pressure recorded in all four limbs showed a significant negative correlation with right arm ES in males and left arm ES in females. Conclusion: Since gender, anthropometric parameters, and blood pressure influence cardiac time intervals, these should be adjusted for when deriving inference on left ventricular performance.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2020,

title = {Role of neutrophil to lymphocyte ratio (NLR) In conjunction with coronary artery involvement as a biomarker for the magnitude of current of injury, type of intervention and clinical outcomes in STEMI},

author = {Mohammed Abdul Hannan Hazari and K. Laxman Rao and Bachi Tazneem and Sara Sana Ayesha Khanum and Huma Quadri and Syeda Kehkashan Jabeen},

url = {https://journalajcr.com/index.php/AJCR/article/view/22},

year  = {2020},

date = {2020-01-17},

urldate = {2020-01-17},

journal = {Asian Journal of Cardiology Research},

volume = {3},

issue = {1},

pages = {1-7},

publisher = {OA Academic Press},

abstract = {Background: The potential prognostic biomarker—neutrophil to lymphocyte ratio (NLR) can be used to predict the severity of STEMI. We conducted an observational study using this parameter together with the extent of coronary artery involvement from coronary angiogram and magnitude of ST-elevation on ECG to determine the prognosis and the length of hospital stay. The effect of early reperfusion with thrombolysis was also observed.

Methods and Results: 30 subjects (age 56.43 ± 13.98), with ST-elevation on ECG at admission, treated with streptokinase and undergoing angiogram were taken for the study. Repeated ECGs and complete blood picture on admission day, day 3, day of discharge and on the follow-up day were obtained. Out of 30 subjects, 15 received thrombolysis out of which 12 (80%) survived compared to the other 15 subjects who presented late, out of which 10 (66.6%) survived. Mean ST-elevation on the day of admission, on day 3, day of discharge and on follow up was found to be 0.39 ± 0.12, 0.18 ± 0.12, 0.05 ± 0.07, 0.00 ± 0.00 respectively. NLR values on admission day were 7.89 ± 4.98, day 3 (6.24 ± 5.05), day of discharge (4.34 ± 2.74) and on follow up (1.71 ± 1.40) indicating association of higher NLR values with magnitude of current of injury. NLR values as high as 18.5 were observed in expired subjects. The length of hospital stay was found to be 6.43 ± 5.03 days.

Conclusion: There was a linear decrement in ST-segment resolution with a decrease in NLR and can be attributed to the natural course of disease and type of intervention provided. Nevertheless, the univariate correlation between ECG and NLR on various days of treatment was not significant.},

key = {AJCR.53641},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019e,

title = {Conflict of interest or competing interest: What is in the name?},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i4.94415},

doi = {10.23921/amp.2019v3i4.94415},

issn = {2456-8422},

year  = {2019},

date = {2019-12-31},

urldate = {2019-12-31},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {4},

pages = {29-30},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019d,

title = {Precision medicine in the era of live cell imaging},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i3.68136},

doi = {10.23921/amp.2019v3i3.68136},

issn = {2456-8422},

year  = {2019},

date = {2019-10-03},

urldate = {2019-10-03},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {3},

pages = {27-28},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019,

title = {A comparative study of central and peripheral arterial parameters in hypertensive patients on angiotensin receptor blockers and calcium channel blockers},

author = {K. Laxman Rao and Mohammed Abdul Hannan Hazari and Bachi Tazneem and Ahmed Abdul Aziz and Asiya Mohtesham and A. Afreen and Kethavath Priyanka},

url = {https://www.jhrr.org/article.asp?issn=2394-2010;year=2019;volume=6;issue=2;spage=76;epage=81;aulast=Rao;type=0},

doi = {10.4103/0028-3886.263243},

issn = {2394-2010},

year  = {2019},

date = {2019-07-23},

urldate = {2019-07-23},

journal = {Journal of Health Research and Reviews},

volume = {6},

issue = {2},

pages = {76-81},

publisher = {Wolters Kluwer - Medknow},

abstract = {Aims: Untreated or inappropriately managed hypertension (HTN) is a significant risk factor for all-cause morbidity and mortality due to its complications. For proper management of HTN, timely diagnosis and classification into appropriate category is crucial. According to hypertensive class category, pharmacological therapy can be initiated according to the national or international guidelines. Various antihypertensive medications have differential effects on peripheral and central arterial parameters. Our study was aimed at comparing the effects of two classes of antihypertensive drugs, i.e., angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs). Materials and Methods: Hypertensive patients on monotherapy – ARBs (Group 1, n = 35) and CCBs (Group 2, n = 35) – over the age of 18 years, belonging to both genders, were recruited. Results: Heart rate and peripheral and central arterial pressures were lower in Group 2 compared to Group 1; ankle brachial index and carotid-femoral pulse wave velocity were less in Group 1 in comparison with Group 2; but these differences were statistically not significant. Conclusions: We conclude that the two groups of drugs were equally effective in blood pressure reduction, both in central and peripheral arteries.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Uzma_2019,

title = {Assessment of neurocognitive impairment in obstructive sleep apnea},

author = {Nazia Uzma and Juhi Fatima Sultan and Nooruddin Owaisi and Mariya Syed and Abid Ali Khan and Ashfaq Hasan},

url = {https://ijop.net/index.php/ijop/article/view/217},

doi = {10.37506/ijop.v7i2.217},

issn = {2320-6039},

year  = {2019},

date = {2019-07-20},

urldate = {2019-07-01},

journal = {International Journal of Physiology},

volume = {7},

issue = {2},

pages = {126-130},

abstract = {Sleep apnea is usually reported in south Indian population. The indications of obstructive sleep apnea (OSA) comprise of breathing difficulties particularly owing to obstruction in the upper airway tract. The present study investigated the effect of the syndrome, the patients documented with OSA, by categorizing the patients into mild, moderate and severe OSA groups depending on apnea-hyponea index (AHI), derived from sleep study (polysomnographic findings). The comparative evaluation of various outcomes considered in this study included healthy individuals (control group, AHI < 5), mild OSA (AHI 5–15), moderate (OSA 15–30) and severe (AHI > 30). Investigations were conducted on the subjects which evaluated baseline characteristics, polysomnographic data and neuro-cognitive performances by Mini-Mental State Examination (MMSE). The results revealed significantly higher body mass index (BMI), snoring and decresed sleep efficiency in patients with sleep apnea syndrome when compared with control group. OSA patients further exhibited compromised neuro-cognitive. The intensity of the impairments and difficulties increased with upsurge in severity of the syndrome among all patients. The findings of this work strongly indicated that impaired executive functioning; neuro-cognitive abnormalities exit in a heightened state among OSA patients, than in the normal healthy individuals, the control group. These findings in aggregate would help clinicians in diagnosis and in understanding the disease prognosis.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019c,

title = {Intracellular divalent ion oscillations: Is this the key phenomenon in rhythm generators?},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i2.54657},

doi = {10.23921/amp.2019v3i2.54657},

issn = {2456-8422},

year  = {2019},

date = {2019-06-30},

urldate = {2019-06-30},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {2},

pages = {19-20},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2019,

title = {Effects of cigarette smoking on erythrocyte sedimentation rate, platelet count, total and differential leucocyte counts in adult male smokers},

author = {Safia Sultana and Nabila Afsar and Mohammed Jawad and Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i1.35185},

doi = {10.23921/amp.2019v3i1.35185},

issn = {2456-8422},

year  = {2019},

date = {2019-03-28},

urldate = {2019-03-28},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {1},

pages = {14-18},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Smoking is one of the leading causes of death worldwide. Smokers have higher risk for coronary heart disease, atherosclerosis, acute myocardial infarction, hypertension, clotting disorders, inflammation, respiratory diseases, cancers, etc. A cigarette smoker is exposed to a number of harmful substances. In this study we hypothesized that smoking causes inflammatory reactions and induces hyperthrombic state in the body which may be reflected in erythrocyte sedimentation rate (ESR), total leucocyte count (TLC), differential leucocyte count (DLC) and platelet count values. The purpose of the study was to study the effects of cigarette smoking on erythrocyte sedimentation rate, total leucocyte count and platelet count in adult male smokers and to compare the results with non-smokers and to establish a relationship between the duration and quantity of smoking with the change in ESR, TLC, DLC and platelet count. A cross sectional study was conducted in the department of Pathology on 86 healthy male subjects (smokers=43 and non-smokers=43). ESR was estimated using Westergrens method. TLC, DLC and platelet counts were estimated using HORIBA Pentra ES60 autoanalyser. TLC and basophil counts were significantly higher in smokers than in non-smokers (p<0.05). The mean value of ESR was higher among smokers than non-smokers but it was statistically insignificant. Platelets counts showed no significant difference between smokers and non- smokers. No correlation was observed in various blood parameters and smoking (in pack years). We conclude that smoking initiates an inflammatory response as evidenced from raised TLC, monocyte and basophil counts.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019b,

title = {Failing immune surveillance in humans: Repercussion of modern day lifestyles},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i1.38529},

doi = {10.23921/amp.2019v3i1.38529},

issn = {2456-8422},

year  = {2019},

date = {2019-03-27},

urldate = {2019-03-27},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {1},

pages = {1-2},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2018,

title = {Blood group reckoning: Unraveling the mystery of blood group antigens},

author = {Mehnaaz Sameera Arifuddin},

url = {https://amphysiol.com/index.php/amp/article/view/v2i4.23002},

doi = {10.23921/amp.2018v2i4.23002},

issn = {2456-8422},

year  = {2018},

date = {2018-12-31},

urldate = {2018-12-31},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {4},

pages = {33-35},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kahkashan_2018,

title = {Variation in carotid-femoral pulse wave velocity, augmentation pressure and augmentation index during different phases of menstrual cycle},

author = {Nudrath Kahkashan and Mehnaaz Sameera Arifuddin and Mohammed Abdul Hannan Hazari and Safia Sultana and Farah Fatima and Syyeda Anees},

url = {https://amphysiol.com/index.php/amp/article/view/v2i3.10454},

doi = {10.23921/amp.2018v2i3.10454},

issn = {2456-8422},

year  = {2018},

date = {2018-11-28},

urldate = {2018-11-28},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {3},

pages = {27-32},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Physiological variation of estrogen and progesterone during menstrual cycle is well known.  They not only have an effect on blood pressure control, but also seem to have a role in regulating arterial compliance. This study was done to find out whether there are any changes in central arterial parameters during different phases of menstrual cycle. Thirty female  subjects  in the  age  group  of  18-22  years  with  normal,  regular menstrual  cycles  participated in this prospective observational study at our teaching hospital. Anthropometric parameters were recorded.  Blood pressure in all 4 limbs was recorded using cardiovascular risk analyzer-Periscope™ on Day 3rd to 5th (follicular phase), Day 12th to 14th (ovulation phase), Day 22nd to 24th (luteal phase) of their menstrual cycle. We collected blood samples during these three phases for estimation of estradiol and progesterone by ELISA technique. Analysis of variance and correlation statistics were done using SPSS 17.0 statistical software. No significant statistical changes were observed in systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, aortic systolic pressure, aortic diastolic pressure, aortic augmentation pressure, aortic index and pulse wave velocity during the three recorded phases of the menstrual cycle. There are many studies which correlate changes in peripheral artery blood pressure with different phases of menstrual cycle. But there is scarcity in data available which correlates central arterial pressures and arterial stiffness with natural hormonal variations in different phases of menstrual cycle. However, our results show that although there are subtle changes in blood pressure parameters along with estrogen and progesterone levels throughout the menstrual cycle, yet these were not statistically significant.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2018c,

title = {Hemorheology: Capturing the fluid dynamics of blood},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v2i3.15965},

doi = {10.23921/amp.2018v2i3.15965},

issn = {2456-8422},

year  = {2018},

date = {2018-11-28},

urldate = {2018-11-28},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {3},

pages = {25-26},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Naeem_2017b,

title = {Influence of glycemic control on platelet count in type II diabetics in absence of vascular complications},

author = {Kazi Husna Abdul Naeem and Mohammed Abdul Hannan Hazari and Farisa Khatoon and Farah Bahmed and Fariha Mohammedi },

url = {https://www.medpulse.in/Physiology/Article/Volume5Issue2/Physiology_5_2_4.pdf},

doi = {10.26611/103524},

issn = {2550-7613},

year  = {2018},

date = {2018-08-23},

urldate = {2018-08-23},

journal = {MedPulse International Journal of Physiology},

volume = {5},

issue = {2},

pages = {22-24},

abstract = {Background: Diabetes mellitus (DM) has attained a state of a global emergency with increasing prevalence worldwide. Altered thrombocyte morphology, count and function have been reported with diabetics. The present study aimed at determining the variation in platelet count with degree of glycaemic control in Type 2 diabetes patients. Methods: A total of 200 subjects were enrolled in the study of which 100 had HbA1c < 6.5 and 100 had HbA1c > 6.5. Sample for glucose estimation and platelet indices were collected and estimation were carried out by the auto-analyzer. The statistical evaluation was done using SPSS version 22. Student t- test was used for comparison between two variables namely HbA1c and platelet count. Results: Mean Platelet count was found to be significantly higher in patients with type -2 diabetes mellitus with HbA1C > 6.5 in comparison to patients having HbA1c < 6.5.(p < 0.01) Conclusion: This study revealed a higher mean platelet count for diabetics with poor glycaemic control than for diabetics with good glycaemic control. However, platelet counts in both groups were within the normal reference range for healthy individuals. Platelet count with other platelet indices like Mean Platelet Volume and Platelet Distribution Width are simple, effective and cheap tests that may be used to predict vascular complications in type 2 DM.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ali_2018,

title = {Prevalence of cuff hypertension among overweight and obese subjects},

author = {Syed Imran Ali and Farisa Khatoon and Mohammed Abdul Hannan Hazari and Nazia Uzma and Fariha Mohammedi},

url = {https://njppp.com/?mno=292752},

doi = {10.5455/njppp.2018.8.0308806032018},

issn = {2231-3206},

year  = {2018},

date = {2018-07-31},

urldate = {2018-07-31},

journal = {National Journal of Physiology, Pharmacy and Pharmacology},

volume = {8},

issue = {7},

pages = {1018-1021},

publisher = {ScopeMed},

abstract = {Background: Obesity is a lifestyle affliction, it is a side effect of poor habit and it can be reversed. Obesity is defined either by increased waist circumference, waist-hip ratio, and/or body mass index. Overestimation of blood pressure (BP) using an inappropriately small cuff is well documented. Using a BP cuff small for midarm circumference (AC) in obese patient's results in higher BP readings. Therefore, it was felt that there is a requirement to study the effect of different cuff sizes for different arm circumferences in obese individuals. The purpose of this study is to determine if cuff hypertension (HTN) is present in obese subjects.

Aims and Objective: To determine the presence of cuff HTN in obese subjects.

Materials and Methods: A total of 200 obese and 200 non-obese subjects between 20 and 50 years of age reporting to OHRC were included in the study. Systolic and diastolic BP were measured using a mercury sphygmomanometer with two cuff sizes, i.e., standard cuff 12 cm width (for MAC <32 cm) and large cuff 15 cm width (for MAC >32 cm).

Results: A total of 56 subjects were diagnosed as systolic HTN with standard cuff, i.e., 28% but with large cuff, it was only 24 subjects, i.e., 12% only, a difference of 16% between the prevalence of systolic HTN. Diastolic HTN diagnosed with standard cuff was 20% compared to large cuff 7.5%, a difference of 12.5%. The above differences are demonstrating 'cuff HTN' in the obese subjects.

Conclusion: In this study of 200 obese and 200 non-obese subjects, it was found that 'cuff HTN' is present in obese subjects.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2018b,

title = {Nanophysiology: Real-time phenomenal perspective in biology},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v2i2.302175},

doi = {10.23921/amp.2018v2i2.302175},

issn = {2456-8422},

year  = {2018},

date = {2018-06-30},

urldate = {2018-06-30},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {2},

pages = {17-18},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sayeed_2018,

title = {Immediate and delayed effect of Ramadan fasting on spirometry parameters},

author = {Adiba Sayeed and Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin},

url = {https://amphysiol.com/index.php/amp/article/view/v2i1.279619},

doi = {10.23921/amp.2018v2i1.279619},

issn = {2456-8422},

year  = {2018},

date = {2018-03-31},

urldate = {2018-03-31},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {1},

pages = {7-10},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Fasting in the month of Ramadan is an obligatory duty for muslims. Researchers have investigated health benefits of fasting and reported conflicting results. The purpose of this study was to determine the immediate and delayed effects of Ramadan fasting on spirometric parameters. 50 apparently healthy young adults aged between 17-27 years, belonging to both genders who fast during the month of Ramadan were enrolled for the study. Spirometric recordings were done at three different time points. First: 5-10 days before the start of Ramadan (Pre-Ramadan); second: within 10 days of the beginning of Ramadan fasting (Ramadan); third: within 7 days of the end of Ramadan (Post-Ramadan). There were no statistically significant differences between the three phases with respect to tidal volume (TV), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1), FEV1/FVC, peak expiratory flow rate (PEFR) and forced expiratory flow 25% to 75% (FEF25-27). To conclude, Ramadan fasting does not have any significant effect on pulmonary function tests as assessed by spirometry. Hence, the diagnosis and prognosis of a respiratory disorder made on spirometry findings are reliable and need no error correction if an individual is fasting.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2018,

title = {Target with-in target},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v2i1.275951},

doi = {10.23921/amp.2018v2i1.275951},

issn = {2456-8422},

year  = {2018},

date = {2018-03-31},

urldate = {2018-03-31},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {1},

pages = {1-2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mohammedi_2018,

title = {Effect of nicotine on platelet function},

author = {Fariha Mohammedi and Mohammed Abdul Hannan Hazari and Farisa Khatoon and Kazi Husna Abdul Naeem and Syed Imran Ali},

url = {https://www.medpulse.in/Physiology/html_5_2_2.php},

doi = {10.26611/103522},

issn = {2550-7613},

year  = {2018},

date = {2018-02-10},

urldate = {2017-02-28},

journal = {MedPulse International Journal of Physiology},

volume = {5},

issue = {2},

pages = {13-16},

publisher = {MedPulse Publishing Corporation},

abstract = {Background: Tobacco is the dried and processed leaves of the plant Nicotiana tobacum that is widely cultivated and commercially grown in many countries of the world. In India, tobacco is taken in several other forms also, for example, Pan (betel quid), dried leaves (Patti), paste (Qiwam, Zarda), tobacco with lime (Khaini/Mawa). Its use is common in various parts of the world, including India and central Asia. An increase in the consumption of tobacco has been noticed among high school students, college students, and sports persons .This is immensely popular in all socio-economic states in India. It is viewed as especially ominous because of the ease , low expense of procurement, youth appeal, convenient shelf life and lack of social stigma. Despite the known health consequences of tobacco chewing‖ is not viewed by users as particularly dangerous and is considered less of a ―social evil‖ than smoking by much of the public. Previous reports have described long-term harmful effects of nicotine on various body parameters.. In view of the various pharmacological actions of nicotine and additives and the wide use in many regions and countries, chronic consumption  may affect the status of hematological parameters and further delineate the effects of tobacco use to health. The effect of smokeless tobacco use on health irrespective of the mode of consumption has been well documented. Objective: this study was conducted to determine hematological effects of nicotine on platelet count and its functions. Materials and Methods: This cross sectional study was done in the department of internal medicine Owaisi Hospital and Research Centre. A detailed assessment was done on 200 apparently healthy subjects, out of which 100 were tobacco chewers and 100 non chewers. Various parameters were recorded which include personal details, department of work, history of smoking , chewing tobacco, history of exposure to tobacco smoke, history of any chronic disease like diabetes mellitus and medication history. Hematological investigations done. Automated blood analyzer was used for estimation of platelet count Results: In tobacco chewers the following platelet parameters are higher than non-chewers. 1. Platelet count -Statistically significant. 2. PCT- not significant statistically.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Yasmeen_2018,

title = {Immediate effects of mobile phone radiations on heart rate variability in college going students},

author = {Juveriya Yasmeen and Mehnaaz Sameera Arifuddin and Nazeema Khatoon and Umaima Mahveen and Mohammed Abdul Hannan Hazari},

url = {https://njppp.com/?mno=273250},

doi = {10.5455/njppp.2018.8.0727708082017},

issn = {2320-4672},

year  = {2018},

date = {2018-01-31},

urldate = {2017-01-31},

journal = {National Journal of Physiology, Pharmacy and Pharmacology},

volume = {8},

issue = {1},

pages = {56-61},

publisher = {ScopeMed},

abstract = {Background: The use of mobile phone has increased excessively these days which can have a deleterious effect on human tissues and organs, especially cardiovascular system (CVS). The effects on CVS can be detected at an early stage by analyzing alterations in heart rate variability (HRV).

Aims and Objectives: This study was designed to determine the effect of mobile phone use with different components of HRV.

Materials and Methods: In our study, HRV was measured in 95 college-going students (males: 49 and females: 46) using root mean square polyrite-D during 3 phases with each phase being recorded continuously for 2 min: Phase 1: Basal recording; Phase 2: Mobile phone use during active call with direct contact to the ear; and Phase 3: Mobile phone use during active call with earphones. Data obtained were subjected to statistical analysis using repeated measures non-parametric test followed by multiple comparison tests.

Results: There was a significant increase in mean HR and decrease in mean RR interval from baseline through Phase 3 to Phase 2. This study shows that there was statistically significant change in root of the mean of the sum of the squares of differences, low frequency (LF), high frequency (HF), and LF/HF ratio between basal recording and during active call (direct contact of mobile phone to the ear and also with use of earphones); however, no change was seen between direct contact of mobile phone to the ear and during the use of earphones. Standard deviation of all normal-to-normal intervals did not show any significant change. We also observed gender differences in some of the HRV parameters.

Conclusion: There is a considerable effect of mobile phone use on HR and HRV parameters. Furthermore, the changes noted are less with earphone use than when compared with the use of mobile phone in direct contact with the ear though these differences were not significant statistically.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Uzma_2017,

title = {Sleep Apnea},

author = {Nazia Uzma and Vontela Devender Reddy},

url = {https://www.nepjol.info/index.php/JGMCN/article/view/17863},

doi = {10.3126/jgmcn.v9i2.17863},

issn = {2070-4240},

year  = {2017},

date = {2017-07-31},

urldate = {2017-07-01},

journal = {Journal of Gandaki Medical College-Nepal},

volume = {9},

issue = {2},

pages = {29-37},

publisher = {Nepal Journals Online (JOL)},

abstract = {Background: Sleep apnea is a condition that interrupts breathing while sleeping, usually caused by an obstruction blocking the back of the throat so that the air cannot reach the lungs. The brief cessation in breath automatically forces individuals to wake up and restart breathing. This can happen many times during the night, making it hard for the body to get enough oxygen, and impacts the sleep quality. It is the most common type of sleep disorder breathing.

Objectives: The present study was designed to investigate the effects of obstructive sleep apnea (OSA) on different mental, physical and nervous disorders which are manifested in such patients. This study would not only benefit in ascertaining the causes of OSA through assessment of higher mental functions of autonomic and peripheral nervous systems but also in the development of algorithm for estimation of degree of damage to the nervous system with severity of OSA.

Methods: A total of 1365 consecutive participants participated in this study at the Department of Pulmonary Medicine, Deccan College of Medical Sciences, Hyderabad, Telangana State, India for suspected sleep disordered breathing (SDB) between October 2012 and February 2016. In this cohort, 1140 participants were deemed ineligible, as per the inclusion criteria. Therefore, 225 patients were considered in the study along with 75 control subjects, who were healthy individuals. The cohort was diagnosed by an experienced pulmonologist for the symptoms of   snoring and daytime somnolence. The data included documentation of age, gender, weight, height, BMI, waist and neck circumference, and clinical data such as history of apnea, insomnia, dyslipidemia, hypertension, and coronary heart disease. All participants underwent overnight polysomnography (PSG) in sleep laboratory. The cognitive function tests consisted of mini-mental state examination and by employing the depression questionnaire (Using Zung self report depression scale). The autonomic function tests were performed. Variabilities in heart rate were determined. Brain natriuretic peptide (BNP) levels in the blood were measured.

Results: The study group had an AHI ≥5 per hour of sleep while the control group had AHI <5 per hour of sleep. Overall, patients in the OSA cohort were older compared to those in the Control cohort. The overnight polysomnography values indicated distinct differences among the parameters of the analysis depending upon the category of the patient (i.e., mild, moderate and severe). Oxygen saturation in blood during both REM and NREM sleep stages clearly indicated lower oxygen in patient cohort than the control group. The cognitive function tests revealed that in comparison to the control group, OSA patients had significantly impaired cognition. OSA patients had significantly higher (p ≤0.05) depression. Motor action, muscle action potential and nerve action potential was significantly lower (p ≤0.05) than that of the control group of healthy patients. The plasma BNP in OSA patients was significantly higher (p ≤0.05) than control subjects. RR intervals in the patient group were significantly shorter than in the control group. The blood pressure of the OSA patients in general was relatively higher than the control group, both during the postural response and in handgrip test.

Conclusions: Among the enrolled individuals, those with severe OSA were affected in all faculties, namely, cognitive abilities and health attributes; and had high BNP levels in their blood. In aggregate, OSA patients can be alleviated from the syndrome, if accurate diagnosis is made on time. This study developed an algorithm which would aid the clinicians in early detection of OSA symptoms and mitigate the prognosis of the syndrome.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Farheen_2017,

title = {Hematological parameters are acutely effected by cement dust exposure in construction workers},

author = {Ayesha Farheen and Mohammed Abdul Hannan Hazari and Farisa Khatoon and Fareen Sultana and Sanam Maria Qudsiya},

url = {https://amphysiol.com/index.php/amp/article/view/v1i1.263312},

doi = {10.23921/amp.2017v1i1.263312},

issn = {2456-8422},

year  = {2017},

date = {2017-04-13},

urldate = {2017-04-13},

journal = {Annals of Medical Physiology},

volume = {1},

issue = {1},

pages = {31-35},

abstract = {Cement dust poses an occupational hazard causing respiratory (owing to its inhalation), dermatological, ocular and hematological problems. The purpose of the current study was to evaluate the effect of occupational exposure of cement dust on hematological parameters in construction workers. Apparently healthy sixty five (65) adult male construction workers aged 25-50 years participated in this study. Three (3.0) ml venous blood samples were collected from each participant for hematological analysis at two different time points, one at 8 AM and second at 4 PM at the end of work shift. Differences in means and test of significance were calculated using paired Student’s t-test. The results revealed that post shift samples showed statistically significant increase (p<0.05) in mean total leukocyte count (TLC), lymphocyte %, monocyte % and eosinophil %  and statistically significant decrease (p<0.05) in mean hemoglobin, red blood cell (RBC) count, packed cell volume (PCV) and platelet count. The present study confirms that hematological parameters are significantly effected in construction workers which may be attributed to the work atmosphere predominated with cement dust.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Qudsiya_2017,

title = {Study of intraocular pressure among individuals working on computer screens for long hours},

author = {Sanam Maria Qudsiya and Farisa Khatoon and Aftab Abdul Khader and Mohammed Asghar Ali and Mohammed Abdul Hannan Hazari and Fareen Sultana and Ayesha Farheen},

url = {https://amphysiol.com/index.php/amp/article/view/v1i1.263328},

doi = {10.23921/amp.2017v1i1.263328},

issn = {2456-8422},

year  = {2017},

date = {2017-04-11},

urldate = {2017-04-11},

journal = {Annals of Medical Physiology},

volume = {1},

issue = {1},

pages = {22-25},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {In today’s world computers are ubiquitous and found in different forms which can effect intraocular pressure (IOP). Present study was undertaken to find out effect of day-to-day exposure to computer screen on IOP in normal individuals. 70 individuals (who met the screening conditions and devoid of obvious ocular pathology and systemic diseases) had their IOP’s checked before and 4 hour after computer session on same day, all working in general day shift, involving reading English printed material. The results showed significant (p<0.005) increase with IOP values before exposure being 17.89±3.25 and 16.99±2.84 and after exposure being 19.67±3.4 and 18.70±2.4 in left and right eye respectively. Increase in IOP was noted in 70% and 67% individuals in left and right eye. Differences in IOP of right and left eye may be due to dominance of eye or direction of script from left to right.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2017,

title = {Effect of stress on erythryocytic osmotic fragility in healthy individuals},

author = {Fareen Sultana and Farisa Khatoon and Mohammed Abdul Hannan Hazari and Sanam Maria Qudsiya and Ayesha Farheen},

url = {https://www.ijcap.org/article-details/3634},

doi = {10.18231/2394-2126.2017.0008},

issn = {2394-2118},

year  = {2017},

date = {2017-03-31},

journal = {Indian Journal of Clinical Anatomy and Physiology},

volume = {4},

issue = {1},

pages = {30-33},

publisher = {IP Innovative Publication Pvt. Ltd.},

abstract = {Background: The aim of the study was to examine relationship between severity of stress and onset/completion of erythrocyte haemolysis in normal healthy individuals.

Materials and Methods: The study was conducted in Physiology department, Deccan College of Medical Sciences, Hyderabad, after approval from the Institutional Review Board. The study included 50 healthy individuals of both the sexes aged between 20 to 50 years. Individuals working for minimum 8 to 10 hours a day were included and individuals suffering from hypertension, obesity, diabetes mellitus, musculo-skeletal disorders, sickle cell disease and goitre were excluded. Osmotic fragility was determined by collecting 2ml of blood from each individual and stored in EDTA tubes. A drop of blood was added to saline solutions of different tonicity arranged in 12 test tubes. The test tubes were seen for onset and end of hemolysis after an hour.

Stress was measured by Cohen’s perceived stress questionnaire and individual were divided into 3 groups viz. low, moderate and high stress categories as per their scores.

Results: Findings were analysed by student’s t-test and completion of hemolysis was earlier in severe stress group compared to mild and moderate. There is no significant difference between males and females regarding point of onset of hemolysis (p=0.41) and end of hemolysis (p=0.37). Stress increases fragility and it was found that RBC fragility was significantly related to severity of stress. Fragility is not affected by gender.

Conclusion: RBC fragility was significantly related to severity of stress and it was found that fragility is not affected by gender.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2017,

title = {Central blood pressure parameters in young adults with and without parental history of hypertension},

author = {Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin and Hamza Zoeb Hussain and Farah Fatima and Nudrath Kahkashan},

url = {https://amphysiol.com/index.php/amp/article/view/v1i1.262334},

doi = {10.23921/amp.2017v1i1.262334},

issn = {2456-8422},

year  = {2017},

date = {2017-03-31},

urldate = {2017-03-31},

journal = {Annals of Medical Physiology},

volume = {1},

issue = {1},

pages = {16-21},

abstract = {Hypertension is increasingly being found in children and adolescence. The purpose of this study was to find out differences in the central arterial (aortic) blood pressure parameters in young adults with hypertensive and normotensive parents. 109 healthy volunteers between the ages of 17 and 25 years were enrolled for the study after taking consent. Brachial artery pressures and aortic parameters were recorded using PeriScope™ which determines aortic parameters and functional vascular age non-invasively based on oscillometric method. The results of this study showed no statistically significant difference between offspring of hypertensive parents and offspring of normotensive parents.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hasan_2017,

title = {Is obstructive sleep apnea more prevalent than central sleep apnea in patients with systolic heart failure? A retrospective study},

author = {Ashfaq Hasan and Nazia Uzma and Fahad Abdullah Bin Breik and Mohammed Abdul Hannan Hazari and C. Narasimhan and L. Rao},

url = {https://www.hilarispublisher.com/archive/jcrdc-volume-3-issue-1-year-2017.html},

doi = {10.4172/2472-1247.1000126},

year  = {2017},

date = {2017-01-01},

urldate = {2017-01-01},

journal = {Journal of Clinical Respiratory Diseases and Care},

volume = {03},

issue = {01},

pages = {126},

publisher = {OMICS Publishing Group},

abstract = {Central sleep apnea (CSA) rather than obstructive sleep apnea (OSA) is widely believed to be the dominant form of sleep apnea (SA) in patients with heart failure (HF). Hitherto, no study has characterized sleep disordered breathing (SDB) in Indian subjects with heart failure and evaluated its impact on severity of HF, which this study attempts to do. A retrospective data-analysis was done in 65 consecutive patients with stable mild-to-moderate HF referred for evaluation on the basis of fatigue and excessive daytime somnolence (EDS) regarded by the institute’s cardiologists. Patients with ejection fraction (EF) <55% or LV fractional shortening of 28% were included in the study. PSG was scored according to current AASM recommendations. Based on the Apnea-Hypopnea Index (AHI), OSA was classified as mild (AHI:5-15), moderate (AHI: 15-30) and severe (AHI: >30). HF was arbitrarily classified as mild (EF:<35%) moderate (EF:35-45%) and severe (EF:45-55%). OSA emerged as the exclusive form of SA (95.4%; n=65) and was more severe in males. Patients with more severe HF tended to be less obese, and interestingly to have less severe OSA. In contrast to Western literature, OSA seems to be by far the most prevalent form of sleep apnea in Indian subjects with HF. HF mortality is known to be high in underweight individuals yet, persons with severe HF are often less obese and partly by reason of a lower BMI, appear to be relatively protected against severe OSA and severe nocturnal hypoxemia. This study thus raises important and intriguing questions which merit further enquiry.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2016c,

title = {Think out of the box},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v1i1.254258},

doi = {10.23921/amp.2017v1i1.254258},

issn = {2456-8422},

year  = {2016},

date = {2016-12-31},

urldate = {2016-12-31},

journal = {Annals of Medical Physiology},

volume = {1},

issue = {1},

pages = {1-2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bahmed_2016,

title = {Relation between respiratory rate and heart rate - A comparative study},

author = {Farah Bahmed and Farisa Khatoon and Barra Ram Reddy},

url = {https://www.ijcap.org/article-details/2970},

doi = {10.5958/2394-2126.2016.00099.2},

issn = {2394-2118},

year  = {2016},

date = {2016-12-31},

urldate = {2016-01-01},

journal = {Indian Journal of Clinical Anatomy and Physiology},

volume = {3},

issue = {4},

pages = {436-439},

publisher = {IP Innovative Publication Pvt. Ltd.},

abstract = {Background: Activity of many physiological subsystems has a well-developed rhythmic character. Often a dependency between physiological rhythms is established due to interaction between corresponding sub-systems. A well-known feature of oscillatory systems and biological oscillators in particular, is their ability to synchronize. The cardiac and respiratory systems each function is an oscillatory manner, providing a nice example of coupled biological oscillators. The present study has been conducted to evaluate the relation between Respiratory rate and Heart rate and comment upon frequency coupling involved in cardiovascular and Respiratory systems.

Materials and Methods: 40 conscious healthy adults belonging to both sexes were screened using standardized digital physiograph. Piezoelectric respiratory belt was used for respiratory recording. A bipolar limb lead ECG was used for cardiac activity.

Results: The data of healthy subjects showed strong variability in heart rate and respiratory rate in a 15 minute recorded segment and subjected to fast Fourier Transforms.

Conclusion: We thereby conclude that frequency coupling is the important aspect of cardio-respiratory interaction as we detected the presence of several different n: m epochs within one record.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Uzma_2016,

title = {Effect of henna (mehndi) on pulse oximetry reading},

author = {Nazia Uzma and Juveria Sultana and Abid Ali Khan and Usama Syed and Ashfaq Hasan},

url = {https://www.ijcap.org/article-details/2998},

doi = {10.5958/2394-2126.2016.00127.4},

issn = {2394-2118},

year  = {2016},

date = {2016-12-31},

urldate = {2016-01-01},

journal = {Indian Journal of Clinical Anatomy and Physiology},

volume = {3},

issue = {4},

pages = {556-559},

publisher = {IP Innovative Publication Pvt. Ltd.},

abstract = {Introduction: Pulse oximetry is a frequently used and a non-invasive method for monitoring oxygen saturation in blood. It estimates arterial hemoglobin saturation by measuring the light absorbance of pulsating vascular tissue at two wavelengths which can be altered by various factors. Numerous factors could lead to inaccuracy or ambiguous information about oxygen saturation and might result in unwanted procedures. In many cultures, women decorate their fingernails and feet with henna. The purpose of this study was to determine the effect of henna on the measurement of oxygen saturation.

Methods: 100 healthy females with a mean age of 19±1.0 years with normal oxygen saturation at room air were included into the study. Individuals with cardiovascular disorders like congenital heart disease, heart failure, any respiratory diseases were excluded from the study. Henna was applied to all the participants on the distal phalanx of left index finger (test) of the individuals and kept for 2 hours whereas right index finger was left empty as control. After 2 hours of application, henna was scrapped off from left finger. Oxygen saturation in addition to radial pulse was determined on both tested and control finger. Similarly, oxygen saturation and radial pulse was again determined on 2nd day as well as on the 7th day of application of henna on both tested and control finger and were statistically compared.

Results: Our results revealed no alteration in radial pulse after henna application even after 07th day (p value more than 0.05 in all the cases). However, a change in oxygen saturation was observed after 2 hours of application of henna till 07th day. Nonetheless, it must be emphasized that an increase of saturation of this minor magnitude (average 0.67%) does not translate into a clinically important change.

Conclusion: Application of natural henna does not cause any major error in measurement of oxygen saturation in young healthy individuals.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2016,

title = {Does anthropometric measurements correlate with hematological parameters after the adolescent growth period?},

author = {Mehnaaz Sameera Arifuddin and Mohammed Abdul Hannan Hazari},

url = {https://ppj.phypha.ir/article-1-1166-en.html},

issn = {2476-5236},

year  = {2016},

date = {2016-09-30},

urldate = {2016-09-30},

journal = {Physiology and Pharmacology},

volume = {20},

issue = {3},

pages = {137-146},

publisher = {Iranian Society of Physiology and Pharmacology},

abstract = {Introduction: Musculoskeletal growth is variable during adolescent period and reaches its maximum by 18 years, whereas hemopoietic parameters reach adult values by 15 years. After adolescence period, the blood parameters may vary with nutrition and built of the individual. The purpose of this study was to find out any correlation between anthropometric and hematological parameters after the adolescent growth period. Methods: Total of 81 subjects (males: 20; females: 61), 18-22 years were analyzed for 4 anthropometric measures and 19 hematological markers. Blood was collected in citrate tubes and analyzed for hematological parameters. Results: Difference between BMI sub-groups with respect to hemoglobin (Hb), red cell distribution width-standard deviation (RDW-SD) and red cell distribution width-coefficient of variation (RDW-CV) in males and females was not significant. In males, height showed negative correlation with mean corpuscular hemoglobin concentration (MCHC) and weight showed positive correlation with hematocrit. BMI positively correlated with Hb. Body surface area (BSA) correlated with red blood cell count (RBC) and hematocrit. In females, height, weight and BSA did not show significant correlation with any of the blood parameters. BMI correlated positively with mid-cell fraction and negatively with mean platelet volume. RDW-SD and RDW-CV did not reveal any statistically significant correlation with height, weight, BMI and BSA in both males and females. Conclusion: In male subjects, hemoglobin concentration positively correlated with BMI whereas RBC count and hematocrit correlated with BSA. In females no such association was noted. RDW did not show any correlation with anthropometric measures in both genders.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sayeed_2016,

title = {Effect of testosterone and estrogen ratio-An indicator of benign prostatic hyperplasia (BPH)},

author = {Qhurrathul Ain Sayeed and Farisa Khatoon and Farah Bahmed and Maria Kaleem},

url = {https://www.ijcap.org/article-details/1883},

doi = {10.5958/2394-2126.2016.00030.x},

issn = {2394-2118},

year  = {2016},

date = {2016-06-30},

urldate = {2016-01-01},

journal = {Indian Journal of Clinical Anatomy and Physiology},

volume = {3},

issue = {2},

pages = {125-130},

publisher = {IP Innovative Publication Pvt. Ltd.},

abstract = {Background: Benign prostatic hyperplasia (BPH) is one of the most common disease and major cause of morbidity in elderly men. Prostatomegaly often used interchangeably with BPH, is a prominent feature of the disease. Although sex steroid hormones play a vital role in prostate growth, their clinical significance is not completely clear. The phenomenon may be correlated with changes of sex hormone in serum of elderly population. Hence, the objective of this study was to study the roles of serum hormones levels – Testosterone (T) and Estradiol (E2) in elderly patients aged 60-75 years who are diagnosed with benign prostatic hyperplasia (BPH) and to understand the correlation between T/E2 ratio over age as markers of prostate disease.

Methods: To conduct this case control study, a population of 30 patients with benign prostatic hyperplasia (BPH) had been selected and 30 well-matched males without BPH as a control group.

Result: Testosterone level declined with age, but serum estrogens level remains unaltered so estrogen may be involved in the development of BPH.

Conclusion: The present study suggests that testosterone estrogen ratio can be an indicator of BPH in patients above 45 years of age.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khatoon_2016,

title = {Visual evoked potential as an early marker of diabetic retinopathy},

author = {Farisa Khatoon and Farah Bahmed and Nazeema Khatoon},

url = {https://www.ijcap.org/article-details/1899},

doi = {10.5958/2394-2126.2016.00046.3},

issn = {2394-2118},

year  = {2016},

date = {2016-06-30},

urldate = {2016-01-01},

journal = {Indian Journal of Clinical Anatomy and Physiology},

volume = {3},

issue = {2},

pages = {200-204},

publisher = {IP Innovative Publication Pvt. Ltd.},

abstract = {Background: Chronic hyperglycemia in diabetes mellitus causes damage to various organs, particularly eyes, kidneys, nerves, heart, and the blood vessels. Visual defects in diabetics occurs due to both vascular and metabolic abnormalities which can affect retina, optic nerve and visual pathway. Change in Visual evoked potential (VEP) response occurs in diabetic patients much earlier than development of overt retinopathy and these changes correlate with duration of disease. Aim of this study was to determine the subtle functional changes in the retina of diabetic eye with the help of VEP before diabetic retinopathy sets in. In the current study comparison between amplitudes, latency P100 of VEP in type 2 diabetes mellitus with that of healthy controls was done.

Method: Cross sectional study using 100 controls and 100 diabetic patients was carried out in the department of Physiology Deccan college of Medical Sciences, Hyderabad. Statistical analysis was done using SPSS software.

Result: Significant association was obtained between duration of diabetes mellitus and P100 latency.

Conclusion: VEP can be used as a very useful electrophysiological indicator of early subtle functional changes of retina in diabetes mellitus.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2016b,

title = {Observational study on the prevalence of diabetes mellitus among ultrasonographically diagnosed cholelithiasis patients},

author = {Mohammed Abdul Hannan Hazari and Shadan Taskeen and Mehnaaz Sameera Arifuddin},

url = {https://www.ijcep.org/index.php/ijcep/article/view/264},

doi = {10.4103/2348-8093.185206},

issn = {2348-8093},

year  = {2016},

date = {2016-04-30},

urldate = {2016-01-01},

journal = {International Journal of Clinical and Experimental Physiology},

volume = {3},

issue = {2},

pages = {77-81},

publisher = {EManuscript Technologies},

abstract = {Background and Aim: Diabetes and cholelithiasis are common diseases worldwide in this era of modern epidemics of non - communicable diseases. Studies revealed that diabetes is a risk factor for gallstones. Since both diseases are related to altered carbohydrate and lipid metabolism, we hypothesized that the vice‑versa, i.e., gallstone disease can be a risk factor for the development of diabetes. The aim of this study was to find the prevalence of diabetes mellitus among ultrasonographically diagnosed cholelithiasis patients and to find any correlation between parameters of gallstones and diabetes mellitus. Methods: This was a hospital‑based observational study. A total of 31 gallstone patients belonging to both genders (male = 9, female = 22) and in the age group of 20–80 years were enrolled in the study. From ultrasound report, parameters noted were: size of gallbladder, solitary or multiple gallstones, and size of the largest gallstone. All patients were asked about history of diabetes mellitus, (if history of diabetes is present – whether the diabetes was diagnosed before or after cholelithiasis), monthly family income, education status, and occupation. Data obtained were subjected to appropriate statistical analysis. P < 0.05 was considered statistically significant. Results: In this endeavor, we found that the prevalence of diabetes among cholelithiasis patients was only 35.48%; and of the 11 diabetic patients, 3 developed gallstones before the diagnosis of diabetes mellitus. Socioeconomic status did not have any bearing on the occurrence of diabetes and gallstones in our patients. Glycated hemoglobin levels did not correlate with the severity of gallstone disease which is assessed in the form of solitary/multiple stones and size of the largest gallstone. Conclusion: There is no increased prevalence of diabetes among cholelithiasis patients. Our hypothesis of gallstones acting as risk for developing diabetes could not be proved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bardia_2016,

title = {Genetic polymorphisms of X-ray repair cross-complementing group 1 and Apurinic/Apyrimidinic endonuclease-1 in chronic obstructive pulmonary disease},

author = {Avinash Bardia and Sandeep Kumar Vishwakarma and Chandrakala Lakki Reddy and N. Raju and Shaik Iqbal and Gallapalli Sravani and Narneni Lavanya and Nazima Begum and Nazia Uzma and Pratibha Nallari and Badruz Zama and Syed Mahmood Ahmed and Ashfaq Hasan and Aleem Ahmed Khan},

url = {https://link.springer.com/article/10.1007/s10753-016-0355-x},

doi = {10.1007/s10753-016-0355-x},

issn = {0360-3997},

year  = {2016},

date = {2016-04-23},

urldate = {2016-04-23},

journal = {Inflammation},

volume = {39},

issue = {3},

pages = {1198–1204},

abstract = {Chronic obstructive pulmonary disease (COPD) is a heterogeneous collection of conditions characterized by irreversible expiratory airflow limitation. The disease is interspersed with exacerbations; periods of acute symptomatic, physiological, and functional deterioration. The present study was designed to investigate the role of X-ray cross-complementing group 1 (XRCC1) and apurinic/apyrimidinic endonuclease 1 (APE1) polymorphisms and the risk of COPD. Blood samples from 354 unrelated subject (age range 18–60 years; 156 with COPD, 198 healthy controls) were collected. Genomic DNA was isolated and genotyped for XRCC1 Arg399Gln and APE1 Asp148Glu using a confronting two pair primers polymerase chain reaction. GA genotype of XRCC1 gene was found to be predominant in the COPD group compared to controls with 1.86-fold increased risk for COPD (OR 1.86, 95 % CI 1.20–2.88, p = 0.0013). TG genotype of APE1 was found to be predominant in COPD group compared to controls with the difference being statistically significant (OR 1.68, 95 % CI 1.08–2.61, p = 0.0043). The GA haplotype was found to be predominant in COPD than controls with a 2.19-fold significant increase (OR 2.19, 95 % CI 1.46–3.28, p = 0.003). Polymorphism in XRCC1 and APE1 gene is associated with an increased risk of COPD.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2016,

title = {Effect of ongoing isometric handgrip exercise on the inspiratory and expiratory reserve volumes},

author = {Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin and Mohammed Abdul Haq Junaid and Mohammed Asghar Ali},

url = {https://njppp.com/?mno=220771},

doi = {10.5455/njppp.2016.6.03032016134},

issn = {2320-4672},

year  = {2016},

date = {2016-01-01},

urldate = {2016-01-01},

journal = {National Journal of Physiology, Pharmacy and Pharmacology},

volume = {6},

issue = {4},

pages = {329-332},

publisher = {ScopeMed},

abstract = {Background: Chronic diseases such as hypertension and diabetes have shown improvement in disease condition on isotonic exercises. But the same can cause deterioration in the health of patients with asthma, heart failure, and chronic obstructive pulmonary disease. Therefore, in such individuals, isometric exercise can be given a try. Isometric exercise is known to activate the autonomic nervous system, especially the parasympathetic fibers and thus has a bearing on the functioning of respiratory system.

Aims and Objectives: This study was undertaken with a purpose to find acute change in respiratory reserve during handgrip exercise.

Materials and Methods: 50 young apparently healthy volunteers between the ages of 18 to 35 years were enrolled for the study. Different spirometry volumes and capacities including inspiratory reserve volume (IRV) and expiratory reserve volume (ERV) were recorded on MedSpiror (RMS, Chandigarh, India) at baseline and during sustained hand grip using a hand dynamometer. Statistical analysis was done using SPSS 17.0 on the data obtained.

Result: This study showed that FVC was significantly reduced during handgrip exercise. FEV1, PEFR, FEF 25-75% and IRV decreased while FEV1/FVC and ERV increased but these changes were not significant statistically.

Conclusion: The reserve capacity of the lung does not change significantly during isometric exercise.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Uzma_2015,

title = {Epidemiology, clinical profiles and risk factors in obstructive sleep apnea},

author = {Nazia Uzma and Ashfaq Hasan and Bhaskarpillai Santhosh Kumar and Hamid Abdul Qaiyum and Doddamani R. Basalingappa and Vontela Devender Reddy},

url = {https://www.minervamedica.it/en/journals/minerva-respiratory-medicine/article.php?cod=R16Y2015N04A0161#},

issn = {2724-6493},

year  = {2015},

date = {2015-12-31},

journal = {Minerva Pneumologica},

volume = {54},

issue = {4},

pages = {161-168},

publisher = {Edizioni Minerva Medica},

abstract = {Obstructive sleep apnea (OSA) is a common medical condition with significant adverse effects but it remains undiagnosed in many individuals. The present hospital based study assessed the prevalence, related clinical features and risk factors of OSA in the South Indian population. One ninety two untreated OSA patients and sixty two control subjects were included in this study. Each subject underwent a fully attended polysomnogram (PSG), spirometric analysis, modified OSA questionnaires and Mallampati score were obtained in study population. The OSA patients were divided into three subgroups: mild (29%), moderate (15%) and severe (56%) and the mean±SD of Apnea-Hypopnea Index (AHI) was 11.4±3, 24.8±5.1 and 36.6±7.4 respectively. Higher Mallampati score was observed in patients with severe OSA than in moderate and mild OSA patients. An apparent decrease in FVC and FEV1 was observed in OSA group with a positive correlation with increase in AHI. A significant decrease in FVC, FEV1 and FEV1/FVC was observed with increase in Body Mass Index (BMI), reflecting the increased restrictive pattern in the OSA groups. Sleep onset latency was increased to 18.6±13.2 than 8.8±3.2 with a sleep efficiency of 74.2±4.8 and 90.2% in OSA group and controls respectively. The apnea index, hypopnea index and microarousals were much higher in the OSA groups than in controls. Statistically significant differences were perceived in the fasting blood glucose levels, triglyceride, LDL, HDL and total cholesterol levels between the OSA group and controls. This study adds evidence for a link between the clinical features, epidemiology and risk factors of OSA.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khatoon_2015,

title = {Correlation of BMI with lipid profile in adult females},

author = {Farisa Khatoon and Asra Tayyab},

url = {https://www.cibtech.org/J-Innovative-Research-Review/Publications/2015/VOL-3-NO-4/03-JIRR-003-FARISA-BMI.pdf},

issn = {2347–4424},

year  = {2015},

date = {2015-12-31},

journal = {International Journal of Innovative Research and Review},

volume = {3},

issue = {4},

pages = {10-11},

abstract = {The present study aimed at assessing the effect of body mass index on lipid profile among adult females. Obesity is important risk factor of dyslipedemia and other related complications. The current study was done to correlate anthropometric indices with lipid profile of individuals. Dyslipedemia is abnormal increase of lipids in body, it is manifested by high levels of cholesterol, low density lipoproteins, and triglycerides. It has gained lot of importance due to various risk factors implicated in causing coronary artery diseases.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid26229751,

title = {Cost-effectiveness analysis of three different combinations of inhalers for severe and very severe chronic obstructive pulmonary disease patients at a tertiary care teaching hospital of South India},

author = {Mohammed Altaf and Ayesha Mubeen Zubedi and Fareesa Nazneen and Shaik Kareemulla and Syed Amir Ali and Mirza Misba Ali Baig and M. Aleemuddin Naveed and Mohammed Abdul Hannan Hazari},

url = {https://journals.lww.com/picp/Fulltext/2015/06030/Cost_effectiveness_analysis_of_three_different.7.aspx},

doi = {10.4103/2229-3485.159940},

issn = {2229-3485},

year  = {2015},

date = {2015-09-30},

urldate = {2015-09-30},

journal = {Perspectives in Clinical Research},

volume = {6},

issue = {3},

pages = {150-158},

publisher = {Wolters Kluwer - Medknow},

crossref = {Altaf_2015},

abstract = {Background: This study aims at simplifying the practical patient management and offers some general indications for pharmacotherapeutic choice by the implementation of (Global Initiative for Chronic Lung Disease) guidelines. This study was designed to evaluate the clinical and economic consequences of salmeterol/fluticasone (SF), formoterol/budesonide (FB), and formoterol/fluticasone (FF) in severe and very severe chronic obstructive pulmonary disease (COPD) patients.

Objectives: The aim was to find out the most cost-effective drug combination between the three combinations (SF/FB/FF) in COPD patients.

Materials and Methods: A prospective observational comparative study (cost-effectiveness analysis), in which 90 severe (30 ≤ forced expiratory volume in 1 s [FEV1] <50% predicted) and very severe (FEV1 < 30% predicted) COPD patients (outpatients/inpatients) who are prescribed with any one of the following combinations (SF/FB/FF) were selected. In our study, we have divided 90 COPD patients into three groups (Group I, Group II, and Group III) each group consisting of 30 patients. Group I was prescribed with medication SF, Group II with medication FB, and Group III with medication FF. We used five different parameters such as spirometry test (mean FEV1 initial and final visit), number of symptom-free days (SFDs), number of moderate and severe exacerbations, Number of days of hospitalization and direct, indirect, and total cost to assess the cost-effectiveness of SF/FB/FF. Comparison of cost and effects was done during the period of 6 months of using SF/FB/FF.

Results: The average FEV1 for Group I, Group II, and Group III subjects at initial visit was 33.47%, 33.73%, and 33.20% and was increased to 36.60%, 35.8%, and 33.4%, respectively. A 3% increment in FEV1 was reported for Group I subjects (SF) and was highly significant statistically (t = −8.833, P = 0.000) at 95% CI. For Group II subjects (FB), a 2% increment in FEV1 was reported and was highly significant statistically (t = −9.001, P = 0.000) at 95% CI. For Group III (FF) subjects 0.2% increment in FEV1. The overall mean total cost for Group I, Group II, and Group III subjects during the 6 months period was found to be Rs. 29,725/-, Rs. 32,602/- and Rs. 37,155/-. Incremental cost-effectiveness of FB versus SF was Rs. 37,781/- per avoided exacerbation and Rs. 661/-per SFD.

Conclusion: This study highlights the favorable therapeutic performance of combined inhaled bronchodilators and corticosteroids (SF/FB/FF), thus suggesting that healthcare costs would be also affected positively. Results from our study showed that SF and FB were the most effective strategies in the treatment of COPD, with a slight clinical superiority of SF. The FF strategy was not much effective (i.e. associated with fewer outcomes and higher costs).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hussain_2015,

title = {Incidence of industrial and domestic cases of deaths due to electrocution},

author = {Iqbal Banu Hussain and Farisa Khatoon and Khazi Mudabbir Ahmed},

url = {https%3A%2F%2Fwww.cibtech.org%2FJ-Innovative-Research-Review%2FPublications%2F2015%2FVOL-3-NO-3%2F10-JIRR-15-FARISA-Electrocution.pdf},

issn = {2347–4424},

year  = {2015},

date = {2015-09-30},

urldate = {2015-09-30},

journal = {International Journal of Innovative Research and Review},

volume = {3},

issue = {3},

pages = {69-70},

abstract = {Deaths from electrocution may be mostly accidental and very rarely suicidal or homicidal electrical energy involving low tension or low voltage currents commonly employed in the home and industry cause most accidents from electric shock. The present study reveals that electrocution deaths be thoroughly documented and investigated for safety, prevention and compensatory reasons. In the present study 43 cases were taken out of which 29 were domestic and 11 were industrial and 3 were unknown.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2015,

title = {Cognitive impairment in type 2 diabetes mellitus},

author = {Mohammed Abdul Hannan Hazari and Barra Ram Reddy and Nazia Uzma and Bhaskarpillai Santhosh Kumar},

url = {https://www.sciencedirect.com/science/article/pii/S1877593411000026?via%3Dihub},

doi = {10.1016/j.ijdm.2011.01.001},

issn = {1877-5934},

year  = {2015},

date = {2015-05-01},

urldate = {2015-05-01},

journal = {International Journal of Diabetes Mellitus},

volume = {3},

issue = {1},

pages = {19-24},

publisher = {Elsevier BV},

crossref = {Hazari_2015},

abstract = {Background: Type 2 diabetes mellitus (T2DM) is a modern day epidemic. Chronic course of diabetes is detrimental to the cognitive functions.

Aim: To decipher the pattern of cognitive impairment in relation to the duration of diabetes.

Study design: Cross-sectional.

Material and methods: T2DM patients (Group I: ⩽5 years duration of diabetes, n = 11; Group II: >5 years duration of diabetes, n = 17) without clinical evidence of central nervous system damage and non-diabetic controls (n = 18) were studied clinically and P300 event-related potentials (ERPs) recorded using three stimuli oddball paradigm. Subjects were examined with Folstein mini-mental state examination (MMSE) for cognitive function and those showing scores more than 26 (maximum score = 30) were enrolled for the study. Patients with known diabetic complications were excluded.

Results: P300 latencies in diabetic group did not relate linearly to the duration of diabetes. Diabetic subgroups with ⩽5 years and >5 years duration of diabetes showed striking differences, patients with over 5 years of disease duration had much prolonged P300 latencies in contrast to patients with 5 years or less disease duration who showed trends similar to that of control group. Differences in P300 amplitudes between groups were non-significant. Hypertensive diabetics showed much prolongation in P300 latencies compared to normotensive diabetics.

Conclusions: P300 ERPs revealed cognitive dysfunction which was not detected by neuro-psychometric test (MMSE). Patients with T2DM have decreased cognitive function which is more prominent when the disease duration exceeds 5 years. Co-existence of hypertension with T2DM further increases the risk of cognitive impairment.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mahmood_2015,

title = {Liver cirrhosis with ascites: Study on identifying reliability parameters for clinical outcome},

author = {Shaikh Mahmood and Badruz Zama and Mohammed Abdul Hannan Hazari},

url = {https://www.ijpcbs.com/articles/liver-cirrhosis-with-ascites-study-on-identifying-reliability-parameters-for-clinical-outcome.pdf},

issn = {2249-9504},

year  = {2015},

date = {2015-03-31},

urldate = {2015-03-31},

journal = {International Journal of Pharmaceutical, Chemical and Biological Sciences},

volume = {5},

issue = {1},

pages = {71-76},

abstract = {Background: Ascites is one of the major complications of liver cirrhosis which usually develop secondary to portal hypertension.

Aim: The purpose of the current study was to evaluate the utility of ratios of few biochemical parameters between serum and ascetic fluid, whether these ratios are more reliable than the actual parameters in diagnosis and prognosis of these patients.

Study design: Cross-sectional study.

Place and duration of study: Owaisi Hospital and Research Centre, Hyderabad, India from July 2012 to December 2013.

Methodology: Biochemical analysis of serum and ascetic fluid focussed on assessing liver function was done. A total of 350 cirrhotic patients of both genders were screened for ascites and 50 among them fulfilling inclusion and exclusion criteria were enrolled for this study. They were assessed for 34 demographic and laboratory parameters including liver function tests, renal function tests and serum electrolytes. We made an attempt to know whether ratio of some of the biochemical parameters in ascitic fluid-to-serum (AF/S) can be more reliable indicators and better prognostic markers in liver cirrhosis with ascites.

Results and Conclusion: In this endeavour, the AF/S ratios of total proteins, albumin, ADA, LDH, GGT and α-amylase did not showed a clear advantage over the existing biochemical analysis in vogue.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}