@article{Karan_2023b,

title = {The effect of durative computer usage on intraocular pressure},

author = {Siddharth Karan and Sheetal Baldava and Rahel Afzal and Farheen Fatima and Saira Begum},

url = {https://www.ijlbpr.com/uploadfiles/29vol12issue4pp162-165.20231019052727.pdf},

issn = {2250-3137},

year  = {2023},

date = {2023-10-31},

urldate = {2023-10-31},

journal = {International Journal of Life Sciences, Biotechnology and Pharma Research},

volume = {12},

issue = {4},

pages = {162-165},

abstract = {Aim: To investigate the changes in the Intraocular pressure (IOP) in adults on prolonged computer usage. Methods:31 adult subjects working with computers for prolonged hours had their Intraocular pressure checked with Schiotz tonometer. Measurements were taken initially on every individual before computer usage and then following 3 hours of computer usage. Results: There was significant rise in the Intraocular pressure (Mean Increase of Intraocular pressure is 1.23mm of Hg) in most of the myopic subjects after 3 hours of continuous usage of computer. Conclusions: Prolonged computer usage could induce transient Intraocular pressure elevation. Mostly Intraocular pressure elevation is seen in myopic subjects whereas emmetropic subjects showed little or no elevation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ali_2023b,

title = {Association between Candida albicans and COVID-19 in complete denture wearers: An observational study},

author = {Mohd. Osman Ali and Babashankar Alva and Suresh Nagaral and Rohit Patil and Mohammad Ullah Khan and Durgesh

A. Tiwari},

url = {https://www.cureus.com/articles/200623-association-between-candida-albicans-and-covid-19-in-complete-denture-wearers-an-observational-study#!/},

doi = {10.7759/cureus.47777},

issn = {2168-8184},

year  = {2023},

date = {2023-10-27},

journal = {Cureus},

volume = {15},

issue = {10},

pages = {e47777},

abstract = {Introduction: The phenomenon of coronavirus disease 2019 (COVID-19)-related candidiasis is gaining increased attention and acknowledgment as an integral component of the severe consequences of COVID-19. The aim of the

present study was to assess the association between Candida albicans and COVID-19 in complete denture wearers.

Materials and methods: An observational study was conducted on 45 complete denture wearers, who were divided into three groups as follows: Group 1, 15 subjects with mild to moderate COVID-19 infection; Group 2, 15 subjects with severe COVID-19 infection; and Group 3, 15 subjects without COVID-19 infection. Mean colony forming units (CFU) were observed on agar plates containing Sabouraud dextrose in the salivary samples of the participants. Analysis of variance, followed by post-hoc analysis by Tukey’s test, was used to compare CFU between the groups. Pearson’s correlation coefficient was used to study the correlation between variables.

Results: The highest average colony-forming units of Candida albicans were observed in Group 2, followed by Group

1, compared to the control group, and a significant (p<0.001) difference was found. A weak positive correlation was found between the age of the patients and the duration of denture usage, as well as between age and the counts of Candida albicans in Groups 1 and 3. This correlation was more pronounced in Group 3. A strong positive correlation was observed in all groups between the Candida albicans count and the duration of denture usage by the patients.

Conclusion: The association between Candida albicans and denture wear was compounded by the presence of COVID-19. Consequently, the timely identification of Candida albicans infection in patients with COVID-19 is

important to establish more efficacious approaches for antifungal treatment and prophylactic interventions.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Iqubal_2023,

title = {Study of testosterone levels in type II diabetes mellitus male patients in Telangana population},

author = {Mohammed Asif Muzaffer Iqubal and Mohammed Mudassir Ali and Mohammed Muneer Ahmed and Juwairia Mohammed Fariduddin},

url = {https://ijpcr.com/volume15issue10/},

issn = {0975-1556},

year  = {2023},

date = {2023-10-19},

journal = {International Journal of Pharmaceutical and Clinical Research},

volume = {15},

issue = {10},

pages = {309-313},

abstract = {Background: Type-II DM affects millions of people in India and globally, but the association between serum testosterone levels (STL) and type-II DM is still unclear, but it impairs reproductive health and quality of life. Method: 95 (ninety-five) type II DM patients of different age groups were studied and compared with 90 normal (controlled) groups. The blood investigation included FBS, PP Blood sugar, Blood urea, serum creatinine, HBA1C, lipid profile, urine albumin, creatinine ratio, serum testosterone were estimated by chemiluminesience immune assay and HbA1c by HPLC. Results: The BMI, age, HBA1C, and serum testosterone level were compared with the control group, and the p value was highly insignificant (p<0.001). Conclusion: The present pragmatic study has confirmed that type II DM patients have significantly lower testosterone and higher sugar level was proved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shaik_2023d,

title = {Health problems in school going adolescent girls in field practice area of tertiary care centre},

author = {Mehaboobi Shaik and Moniza Maheen},

url = {http://www.ijlbpr.com/uploadfiles/123vol12issue3pp630-636.20230802064005.pdf},

issn = {2250-3137},

year  = {2023},

date = {2023-09-30},

urldate = {2023-09-30},

journal = {International Journal of Life Sciences, Biotechnology and Pharma Research},

volume = {12},

issue = {3},

pages = {630-636},

abstract = {Background: Adolescents form precious human resources in every country \& constitute 18% of the total population in India. Adolescence is a period of rapid physical growth, sexual and psychological changes. The aim of the study is to assess the health problems and health issues in Adolescent girls. Their physical growths were also studied. Methods: It is a cross-sectional study carried out among school-going adolescent girls of standard 6 to 10 in the field practice area of a medical college in Hyderabad. The study duration was from February 2022 to January 2023. The data collection tool used for the study was a semi-structured questionnaire. The data was analysed by using SPSS 20 software. Results: Among the total of 904 participants 60.1% belong to the 13-15 years age group and the majority belonged to class II socioeconomic status i.e. 45.6%. Around 79.2% are having skin problems. Among them, 37.1% have hair fall problems and 25.6% have multiple problems. Girls with any episode of illness from the past 15 days show stomach pain at 22.9% and headache at 15.9%. Conclusion: Health problems were found during health check-ups, indicating the need for regular health services. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shaik_2023c,

title = {Knowledge, attitude and practices of reproductive health among adolescent girls in field practice area of tertiary care centre, Hyderabad},

author = {Mehaboobi Shaik and Sayeedunnisa Sarah and Moniza Maheen},

url = {http://www.ijlbpr.com/uploadfiles/135vol12issue3pp694-699.20230809043213.pdf},

issn = {2250-3137},

year  = {2023},

date = {2023-09-30},

urldate = {2023-09-30},

journal = {International Journal of Life Sciences, Biotechnology and Pharma Research},

volume = {12},

issue = {3},

pages = {694-699},

abstract = {Background: Adolescents form precious human resources in every country \& constitute 18% of the total population in India.The majority of adolescents lack basic knowledge about puberty, growth during puberty, safe sex, and hygiene. Adolescence is a period of rapid physical growth, sexual and psychological changes. Aim: The aim of the study was to understand the knowledge, attitude regarding reproductive health and to assess the practices regarding reproductive health among school-going adolescent girls of 6th to 10th standard. Methods: It is a cross-sectional study carried out among school-going adolescent girls of standard 6 to 10 in the field practice area of a medical college in Hyderabad. The study duration was from February 2022 to January 2023. The data collection tool used for the study was a semi-structured questionnaire. The data was analysed by using SPSS 20 software. Results: Among the total of 904 participants 45.7% were scared during the first menstrual cycle. Dysmenorrhoea was most common in class IV socioeconomic status (53.7%).31.4% of study participants had occasional itching and 5.3% had continuous itching. About 10.6% of study participants consulted doctors during menstruation of which the majority of them belonged to 10 to 12 years (16.3%). 58.6% of study participants did household activities during menstruation of which the majority were studying 9th class (69.2%). Conclusion: The present study concluded that female adolescents had unsatisfactory knowledge, inadequate hygiene practices, and positive attitudes toward Reproductive Health.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2023d,

title = {Assessment of soluble thrombomodulin and soluble endoglin as endothelial dysfunction biomarkers in seriously ill surgical septic patients: correlation with organ dysfunction and disease severity},

author = {Mohammed Affan Osman Khan and Tarun Kumar Suvvari and Syed Asif Shah Harooni and Aleem Ahmed Khan and Syyeda Anees and Bushra},

url = {https://link.springer.com/article/10.1007/s00068-023-02369-8},

doi = {10.1007/s00068-023-02369-8},

issn = {1863-9933},

year  = {2023},

date = {2023-09-23},

urldate = {2023-09-01},

journal = {European Journal of Trauma and Emergency Surgery},

publisher = {Springer Science and Business Media LLC},

abstract = {Background: Sepsis, a complex condition characterized by dysregulated immune response and organ dysfunction, is a leading cause of mortality in ICU patients. Current diagnostic and prognostic approaches primarily rely on non-specific biomarkers and illness severity scores, despite early endothelial activation being a key feature of sepsis. This study aimed to evaluate the levels of soluble thrombomodulin and soluble endoglin in seriously ill surgical septic patients and explore their association with organ dysfunction and disease severity.

Methodology: A case control study was conducted from March 2022 to November 2022, involving seriously ill septic surgical patients. Baseline clinical and laboratory data were collected within 24 h of admission to the Surgical Intensive Care Unit. This included information such as age, sex, hemodynamic parameters, blood chemistry, SOFA score, qSOFA score, and APACHE-II score. A proforma was filled out to record these details. The outcome of each patient was noted at the time of discharge.

Results: The study found significantly elevated levels of soluble thrombomodulin and soluble endoglin in seriously ill surgical septic patients. The RTqPCR analysis revealed a positive correlation between soluble thrombomodulin and soluble endoglin levels with the qSOFA score, as well as, there was a positive association between RTqPCR soluble thrombomodulin and the SOFA score. These findings indicate a correlation between these biomarkers and organ dysfunction and disease severity.

Conclusion: The study concludes that elevated levels of soluble thrombomodulin and soluble endoglin can serve as endothelial biomarkers for early diagnosis and prognostication in seriously ill surgical septic patients.},

key = {pmid37741913},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sebastian_2023,

title = {Heart failure: Recent advances and breakthroughs},

author = {Sneha Annie Sebastian and Edzel Lorraine Co and Arun Mahtani and Inderbir Padda and Mahvish Anam and Swapna Susan Mathew and Ayesha Shahzadi and Maha Niazi and Shubhadarshini Pawar and Gurpreet Johal},

url = {https://www.sciencedirect.com/science/article/abs/pii/S0011502923001141?via%3Dihub},

doi = {10.1016/j.disamonth.2023.101634},

issn = {0011-5029},

year  = {2023},

date = {2023-09-12},

urldate = {2023-09-01},

journal = {Disease-a-Month},

pages = {101634},

publisher = {Elsevier BV},

abstract = {Heart failure (HF) is a common clinical condition encountered in various healthcare settings with a vast socioeconomic impact. Recent advancements in pharmacotherapy have led to the evolution of novel therapeutic agents with a decrease in hospitalization and mortality rates in HF with reduced left ventricular ejection fraction (HFrEF). Lately, the introduction of artificial intelligence (AI) to construct decision-making models for the early detection of HF has played a vital role in optimizing cardiovascular disease outcomes. In this review, we examine the newer therapies and evidence behind goal-directed medical therapy (GDMT) for managing HF. We also explore the application of AI and machine learning (ML) in HF, including early diagnosis and risk stratification for HFrEF.},

key = {pmid37704531},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Anis_2023b,

title = {Outbreak of severe myocarditis in England: havoc by a harmless virus},

author = {Heeba Anis and Akbar Basha Shaik and Angad Tiwari and Abel Alemayehu and Abubakar Nazir and Linda Atulinda and Magda Wojtara and Olivier Uwishema},

url = {https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.1541},

doi = {10.1002/hsr2.1541},

issn = {2398-8835},

year  = {2023},

date = {2023-08-31},

urldate = {2023-08-01},

journal = {Health Science Reports},

volume = {6},

issue = {9},

pages = {e1541},

publisher = {Wiley},

abstract = {Background: The World Health Organization (WHO) has been alerted to a concerning upsurge of severe myocarditis, an inflammatory heart condition, in neonates within Wales and South West England. The myocarditis cases are being intricately associated with enterovirus infection, belonging to the Picornaviridae family. The concerned pathogen poses a significant global disease burden, with an estimated 10 to 15 million symptomatic cases occurring annually in the United States alone. Neonates are particularly vulnerable with children under the age of one accounting for approximately 40% of enterovirus infections. Material and Methods: A comprehensive literature search was conducted using various databases including ClinicalTrials, Google Scholar, PubMed, ScienceDirect, MEDLINE, and Ovid Resources. The search strategy included utilizing keywords such as “myocarditis,” “Randomized controlled trials (RCTs). Only articles written in English were considered, and selection criteria included relevance to the research objectives, reasonable sample sizes, and robust methodology. In addition to the identified articles, meta-analyses, animal models and studies, and references from the selected articles were also examined to ensure a comprehensive review of the literature. Results: Ten hospitalized neonates, reported in the United Kingdom (UK), with positive PCR tests were reported to have myocarditis, predominantly caused by coxsackieviruses. The current situation in the region has brought global attention. With this study, we hope to draw attention to the critical aspects of the illness and, more crucially, the present strategies required to control the disease outbreak in England. Discussion: Current European Society of Cardiology (ESC) recommendations for the treatment of acute heart failure apply. Emerging research supports the use of immunosuppressive medication in some circumstances. Patients are advised to avoid aerobic activities for several months after healing. Neonatal enterovirus infections can vary in how they respond to IVIG therapy. The majority of enterovirus infections are self-limited, require no special therapy, and only little supportive care is required. Conclusion: The recent elevation in numbers for reported severe myocarditis in neonates within Wales and South West England, linked to enterovirus infection, poses a significant public health concern. Myocarditis caused by enteroviruses, particularly Group B coxsackieviruses, is associated with significant mortality rates. Diagnosis is supported by non-invasive techniques and cardiac enzyme blood tests. Treatment modalities primarily involve a palliative approach.},

key = {pmid37662542},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2023b,

title = {Virovore: a breakthrough in virology},

author = {Qamar Sultana and Sumitaksha Banerjee and Vibhor Agrawal and Dattatreya Mukherjee and Ranjit Sah and Vikash Jaiswal},

url = {https://journals.sagepub.com/doi/10.1177/11786361231190333},

doi = {10.1177/11786361231190333},

issn = {1178-6361},

year  = {2023},

date = {2023-08-21},

urldate = {2023-08-21},

journal = {Microbiology Insights},

volume = {16},

publisher = {SAGE Publications},

key = {pmid37621408},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Manorenj_2023b,

title = {Diffusion restriction in bilateral thalami: beyond artery of percheron infarct},

author = {Sandhya Manorenj and Reshma Sultana Shaik and Sravan Kumar Marupaka and Tasneem Ara},

url = {https://www.neurologyindia.com/temp/ni714754-1719339_044633.pdf},

doi = {10.4103/0028-3886.383876},

issn = {0028-3886},

year  = {2023},

date = {2023-08-18},

urldate = {2023-08-18},

journal = {Neurology India},

volume = {71},

issue = {4},

pages = {754-759},

publisher = {Medknow},

abstract = {Background: Bilateral thalamic infarction, especially the medial thalamus, has been characteristically described in the artery of Percheron (AOP) affection. However, bilateral thalamic restriction has been described in many entities beyond the AOP infarction. Objective: Here we describe a case series (three cases) with infection as an etiology for bilateral thalamic lesions in the topographic distribution of the AOP from a tertiary care center in tropical India. Materials and Methods: Case series during a 1-year period collecting cases with bilateral thalamic diffusion restriction on MRI who did not have thalamic infarcts and their outcomes. Results: Bilateral thalamic lesion can occur in both bacterial and viral infections such as tuberculosis, dengue, and SARS-COV-2. Thus, we intend to add infections as one of the etiologies in the ever-expanding list of conditions that produce bilateral thalamic restriction. Conclusions: All the acute symmetric thalamic lesions are not always secondary to vascular insult. Accurate assessment and prompt diagnosis can prevent unnecessary delays in treatment. To our knowledge, this is the first case series in the literature that throws light on the bilateral thalamic lesions in the topographic distribution of the AOP secondary to infections in a tropical country like India.},

key = {pmid37635510},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2023,

title = {A comprehensive review on neuroendocrine neoplasms: Presentation, pathophysiology and management},

author = {Qamar Sultana and Jill Kar and Amogh Verma and Shreya Sanghvi and Nirja Kaka and Neil Patel and Yashendra Sethi and Hitesh Chopra and Mohammad Amjad Kamal and Nigel H. Greig},

url = {https://www.mdpi.com/2077-0383/12/15/5138},

doi = {10.3390/jcm12155138},

issn = {2077-0383},

year  = {2023},

date = {2023-08-05},

urldate = {2023-08-01},

journal = {Journal of Clinical Medicine},

volume = {12},

issue = {15},

pages = {5138},

publisher = {MDPI AG},

abstract = {Neuroendocrine neoplasms (NENs) are a group of heterogeneous tumors with neuroendocrine differentiation that can arise from any organ. They account for 2% of all malignancies in the United States. A significant proportion of NEN patients experience endocrine imbalances consequent to increased amine or peptide hormone secretion, impacting their quality of life and prognosis. Over the last decade, pathologic categorization, diagnostic techniques and therapeutic choices for NENs\textemdashboth well-differentiated neuroendocrine tumors (NETs) and poorly differentiated neuroendocrine carcinomas (NECs)\textemdashhave appreciably evolved. Diagnosis of NEN mostly follows a suspicion from clinical features or incidental imaging findings. Hormonal or non-hormonal biomarkers (like serum serotonin, urine 5-HIAA, gastrin and VIP) and histology of a suspected NEN is, therefore, critical for both confirmation of the diagnosis and classification as an NET or NEC. Therapy for NENs has progressed recently based on a better molecular understanding, including the involvement of mTOR, VEGF and peptide receptor radionuclide therapy (PRRT), which add to the growing evidence supporting the possibility of treatment beyond complete resection. As the incidence of NENs is on the rise in the United States and several other countries, physicians are more likely to see these cases, and their better understanding may support earlier diagnosis and tailoring treatment to the patient. We have compiled clinically significant evidence for NENs, including relevant changes to clinical practice that have greatly updated our diagnostic and therapeutic approach for NEN patients.},

key = {pmid37568540},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khatoon_2023,

title = {A clinico-histopathological and etiological assessment of different cutaneous granulomatous lesions},

author = {Rubiya Khatoon and Venu Somanapally and Naushaba Tazeen},

url = {https://www.jcdronline.org/admin/Uploads/Files/64a958b5e136d9.71957212.pdf},

issn = {0975-3583},

year  = {2023},

date = {2023-07-31},

urldate = {2023-07-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {14},

issue = {7},

pages = {446-449},

abstract = {Aim: This study was conducted with the aim to evaluate the frequency and patterns of different cutaneous granulomatous lesions with its clinico-histopathological correlation to reach etiological diagnosis. Materials and Methods: The present cross-sectional observational was conducted in the Department of Pathology, Mamata Academy of Medical Sciences, Hyderabad for the period of 1 year. This study enrolled 100 cases of skin biopsies after histopathological confirmation of granulomatous lesions. Results: 100 cases were studied in which male predominance was noted in 64 (64%) cases and females constituted 36 (36%) cases. Most of the patients were noted in age group of 21 to 31 years i.e 36 (36%) cases followed by 20 (20%) cases in 31 to 41years. 86% of cases were seen below 50 years of age in ourstudy. Leprosy remained the significant causative reason for infectious granulomatous dermatoses succeeded by tuberculosis of skin. Borderline tuberculoid leprosy was found to be predominant, constituting 24 (24%) cases followed by indeterminate type 22 (22%) cases and lepromatous leprosy 21 (21%) cases, tuberculoid leprosy 18 (18%) cases and 8 (8%) cases of borderline lepromatous leprosy.Lupus vulgaris constituted 2 cases (2%) and only 2 (2%) case of sarcoidosis was found. Conclusion: Leprosy was the most common cause of cutaneous granuloma followed by Tuberculosis,fungal infection and foreign body reaction. Among the cases of leprosy, borderline tuberculoid leprosy and tuberculoid leprosy were the commonest subtype. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2023,

title = {Multisystem inflammatory syndrome in children (MIS-C) of Asian countries: a mini-literature review on its clinical characteristics and outcomes},

author = {Mehnaaz Sameera Arifuddin and Mohammed Abdul Hannan Hazari},

url = {https://esmed.org/MRA/mra/article/view/4070},

doi = {10.18103/mra.v11i7.2.4070},

issn = {2375-1924},

year  = {2023},

date = {2023-07-29},

urldate = {2023-07-29},

journal = {Medical Research Archives},

volume = {11},

issue = {7.2},

pages = {1-7},

abstract = {COVID-19 pandemic though has reached endemic levels in most of the countries, it has left an indelible mark on the healthcare systems across the world. One of the emerging challenges faced by physicians and researchers all around the world is the increased incidence of Multisystem inflammatory syndrome in children (MIS-C). Most of the research work conducted till date focusses on the pathophysiology, management and treatment of this syndrome. Multisystem inflammatory syndrome in children has been found to be a consequence of hyperactive immune system resulting from cytokine activation and release of immune complexes subsequent to COVID-19 infection. This condition is also associated with multisystem dysfunction which if not diagnosed early and not treated promptly, could result in an increased mortality among children. Most of the cases have been reported from European and American countries, but not many from Asia. 

This literature review provides for plausible reasons as to why the incidence of multisystem inflammatory syndrome in children has been less in Asian countries compared to the rest of the world. It also gives insights into the treatment protocols for multisystem inflammatory syndrome in children followed by hospitals in these countries and also highlights how different MIS-C is from Kawasaki disease in terms of clinical presentation since both these conditions share a common disease spectrum. This review also lists out the clinical features and treatment followed in such patients belonging to Asian countries.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2023,

title = {In vitro isolation and characterization of multipotent postnatal stem cells from human dental pulp: an approach for regeneration of neural crest tissue},

author = {Nikhat Fatima and Aleem Ahmed Khan and Sandeep Kumar Vishwakarma},

url = {https://journals.lww.com/jpbs/fulltext/2023/15002/in_vitro_isolation_and_characterization_of.61.aspx},

doi = {10.4103/jpbs.jpbs_232_23},

issn = {0976-4879},

year  = {2023},

date = {2023-07-11},

urldate = {2023-07-01},

journal = {Journal of Pharmacy and BioAllied Sciences},

volume = {15},

issue = {Suppl 2},

pages = {S1040-S1042},

publisher = {Medknow},

abstract = {Postnatal dental pulp tissues give the proper justification of the stem cell assimilation and characteristic of the multipotent of the stem cells. Researchers use an in vitro isolation process for clarifying the different stages of staining and cell division. Data collected from various sources helps in understanding how the stem cells help in tissue regeneration. It highlights the immunological phenotypes with the synthesis with cDNA for mentioning molecular immunology. Study also mentions the mitochondrial consistency to measure the potentiality regarding the immunology and the way it differs from 0 to 21 days. Researchers also mention the way for the future development by utilizing the key advantages and definite multipotent of the dental stem cells.},

key = {pmid37693979},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gangannapalle_2023,

title = {Nanoparticle albumin‑bound paclitaxel and solvent-based paclitaxel as chemotherapy options for patients with advanced gastric cancer: a systematic review and meta-analysis},

author = {Mahesh Gangannapalle and Husna Shahnoor and Lubna Sattar and Talwinder K. Nagi and Marwah Al-Tekreeti and Muhammad Waqas Khan and Madiha D. Haseeb and Areeba Khan},

url = {https://www.cureus.com/articles/168559-nanoparticle-albuminbound-paclitaxel-and-solvent-based-paclitaxel-as-chemotherapy-options-for-patients-with-advanced-gastric-cancer-a-systematic-review-and-meta-analysis#!/authors},

doi = {10.7759/cureus.41711},

issn = {2168-8184},

year  = {2023},

date = {2023-07-11},

urldate = {2023-07-01},

journal = {Cureus},

volume = {15},

issue = {7},

pages = {e41711},

publisher = {Springer Science and Business Media LLC},

abstract = {The aim of this study is to assess and compare the effectiveness and safety of nanoparticle albumin-bound paclitaxel (nab-PTX) and solvent-based PTX (sb-PTX) as treatment options for advanced gastric cancer. This meta-analysis was reported according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. We carried out a comprehensive search of PubMed, Google Scholar, and EMBASE from inception to June 15, 2023. The search strategy included the following keywords: "Nanoparticle albumin-bound paclitaxel," "solvent-based paclitaxel," and "advanced gastric cancer," along with their synonyms and medical subject heading (MeSH) terms. In this meta-analysis, the primary outcome was the comparison of overall survival and progression-free survival between the two groups. For safety purposes, we compared the risk of hematological and non-hematological events between the two groups. Four studies were included in this meta-analysis enrolling 1052 patients (483 received nb-PTX and 569 received sb-PTX). In terms of efficacy, nab-PTX showed favorable trends in overall survival and progression-free survival, despite no statistically significant differences being reported. The subgroup meta-analysis showed that nab-PTX seemed to have a better effect on peritoneal metastasis compared to sb-PTX. Regarding safety, the number of patients with neutropenia and leucopenia was significantly higher in the nab-PTX group compared to the sb-PTX group. However, the difference was statistically insignificant. Future research should focus on conducting more robust studies to further validate these findings and establish a stronger evidence base for the use of nab-PTX in this patient population.},

key = {pmid37575705},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2023c,

title = {Irritant contact dermatitis due to povidone-iodine following a surgical intervention: an unusual case report},

author = {Mohammed Affan Osman Khan and Rithika Ramadugu and Tarun Kumar Suvvari and Vijayalakshmi M. and Vimal Thomas},

url = {https://journals.sagepub.com/doi/epub/10.1177/2050313X231185620},

doi = {10.1177/2050313x231185620},

issn = {2050-313X},

year  = {2023},

date = {2023-07-04},

urldate = {2023-01-01},

journal = {SAGE Open Medical Case Reports},

volume = {11},

publisher = {SAGE Publications},

abstract = {The most common day-to-day antiseptic preparation used before any surgery usually involves povidone-iodine. Any irritant reaction to it can be devastating for the patient’s aspect and would raise the need for a preliminary investigation prior to going through any antiseptic preparation. In literature, very few cases were reported on irritant dermatitis with povidone-iodine in Indian setting. We present a case of an 18-year-old female presented with irritant contact dermatitis due to povidone-iodine following a surgical intervention.},

key = {pmid37434898},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nidha_Fatima_2023,

title = {A case report of Kocher Debre Semelaigne syndrome \textendash congenital hypothyroidism with pseudomuscular hypertrophy},

author = {Nidha Fatima and Faraaz Adil and Habib Khan Gulab Khan Pathan},

url = {https://mansapublishers.com/index.php/ijch/article/view/3956/3281},

doi = {10.32677/ijch.v10i7.3956},

issn = {2349-6118},

year  = {2023},

date = {2023-07-01},

urldate = {2023-07-01},

journal = {Indian Journal of Child Health},

volume = {10},

issue = {7},

pages = {90-91},

publisher = {Mansa STM Publishers},

abstract = {Kocher Debre Semealaigne Syndrome (KDSS) is a rare condition with the manifestation of hypothyroidism associated with pseudomuscular hypertrophy. This syndrome is rare in countries with screening programs for hypothyroidism at birth. We are reporting a rare case of KDSS in which earlier diagnosis and treatment would result in the reversal of many symptoms. The main objective of presenting this case is to enlighten pediatricians about prompt diagnosis and timely management to prevent avoidable complications.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fathima_2023,

title = {Self-directed learning: health care professional's perspective-a study},

author = {Munazza Fathima and Syeda Noorul Absar and Ghulam Subhani and Neeraj Sadiq and Mohammed Khaleel and Mohammed Mohsin and Madhipati Sai Krishna},

url = {http://ajms.alameenmedical.org/ArticlePDFs/6%20AJMS%20V16.N3.2023%20p%20216-222.pdf},

issn = {0974-1143},

year  = {2023},

date = {2023-07-01},

urldate = {2023-07-01},

journal = {Al Ameen Journal of Medical Sciences},

volume = {16},

issue = {3},

pages = {216-222},

abstract = {Background: Self-directed learning is a teaching learning method emphasized as a part of newly developed competency based medical education (CBME) which was implemented in 2019 and since then it is an active part of the curriculum. Aims and Objectives: To evaluate the shift in learning process from teacher based education to a student based instruction by assessment of Self-Directed Learning Readiness (SDLR) scores among health professional’s medical students, nursing students, Physiotherapy and Pharmacy students. Material and Methods: A questionnaire based prospective observational study was done in Deccan College of Medical Sciences from Aug 2022 to October 2022. Statistical analysis was done using R language. Results: Maximum SDLR score obtained was 105 and minimum was 21. Scores <80 were considered low and > 80 as high. SDLR scores of most students were low. The scores were comparable to other studies like a South Indian study done who reported a mean SDLRS score in the low readiness category and some studies scores were high readiness to learn. Conclusion: Most students are ready for self- directed learning but their scores need to improve.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jindal_2023,

title = {Scoring system for the use of nebulizers in the primary care settings: an expert consensus statement},

author = {Surinder K. Jindal and Shrikant Pawar and Ashfaq Hasan and Aloke Ghoshal and Raja Dhar and Subodh K. Katiyar and K. S. Satish and Deepak Talwar and Sundeep Salvi},

url = {https://pubmed.ncbi.nlm.nih.gov/37355847/},

doi = {10.5005/japi-11001-0273 },

issn = {0004-5772},

year  = {2023},

date = {2023-06-30},

urldate = {2023-06-30},

journal = {Journal of the Association of Physicians of India},

volume = {71},

issue = {6},

pages = {11-12},

abstract = {Background: The use of nebulizers is an important and useful method for delivering drugs to the lungs in patients with various airway and lung parenchymal disorders. They are primarily used in patients with acute symptoms and in a selected group of patients for maintenance treatment.Its use has increased, especially during the coronavirus disease 2019 (COVID-19) pandemic. To ensure the appropriate use of nebulizers by primary care physicians and to guide them, we aimed to develop a simple nebulizer use score.Methods: An expert working group (EWG) of pulmonologists were formed who using a semi-Delphi method, developed a list of variables and a cut-off score to decide when to use nebulizers. We started with a total of 55 variables that were developed through an exhaustive review of the literature. These were further reduced to smaller numbers that had the maximum score as well as concordance with the EWG. The scores ranged from 1 to 10 (completely disagree to completely agree), and only those above 7.5 were selected.Results: A total of 8 variables with the highest scores were selected (Table 1), which had a total maximum score of 40. A score of <15 was suggested to indicate no use of nebulizer and >20 to suggest definite use of nebulizer. A score between 15 and 20 was suggested for physician judgment.A separate table of 12 conditions was made where the use of nebulizers was mandatory.Conclusion: This first-of-its-kind nebulizer score can be used by primary care physicians to decide which patients should be put on nebulizer treatment.},

key = {pmid37355847},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bari_2023b,

title = {Functional and radiological outcome by various modalities of surgical fixation of proximal humerus fracture},

author = {Mohammed Abdul Bari and Mohammed Hassan Rafeeq and Bandela Venugopal and Mohmad Irfan Nagnur},

url = {https://www.jcdronline.org/admin/Uploads/Files/6493ad4bac2d60.00919020.pdf},

issn = {0975-3583},

year  = {2023},

date = {2023-06-30},

urldate = {2023-06-30},

journal = {Journal of Cardiovascular Disease Research},

volume = {14},

issue = {6},

pages = {1122-1129},

abstract = {In this study, we wanted to test the efficacy and functional outcome of locking compression plate in proximal humerus fractures, evaluate the incidence of complication that may occur with locking compression plate in proximal humerus fractures, study different modalities of fixations in proximal humerus fractures, and assess and compare the functional outcome. Material and Methods: This was a hospital based observational study conducted among 20 patients who were diagnosed with proximal humerus fracture attending the Department of Orthopaedics, Deccan College of Medical Sciences, Tertiary Care Centre, Hyderabad, from October 2018 to August 2019 after obtaining clearance from the institutional ethics committee and written informed consent from the study participants. Results: ORIF with LCP (35%) was the most common modality of treatment. Percutaneous pinning was done in 20% of the patients. 15% of them had CRIF with IM nails. ORIF with k wires and ORIF with k wires and cancellous wires were done in 10% of patients each. Shoulder hemiarthroplasty and ORIF with Ethibond suture were done in 5% of patients each. 55% of the patients developed complications in the post-operative period in the form of infections and stiffness. Of the twenty patients, four (20%) had excellent results, thirteen patients (65%) had satisfactory results, one (5%) had unsatisfactory results and one (5%) was a failure. Conclusion: Proximal humerus fractures are more common in 30-39 years and 40-49 years. It is more common in females. The most common cause is RTA. 2-part fracture is most common. ORIF with LCP was the most common modality of treatment. About half the patients had complications in the form of infections and stiffness.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nasirabadi_2023,

title = {Somatic symptoms disorder},

author = {Minhajzafar Nasirabadi},

url = {https://www.tjima.org/journal/index.php/tjima/article/view/105/161},

year  = {2023},

date = {2023-06-28},

urldate = {2023-06-28},

journal = {Telangana Journal of IMA},

volume = {3},

issue = {1},

pages = {1-2},

abstract = {We Indians are not trained to express our emotions. We don’t speak when we suffer from emotional or psycho-logical  disturbances.  This  repression  of   emotions  or  psychological  disturbances  are  expressed  in  physical  form.  Thus  many  times  psychological  disorders  mask  themselves   underneath   physical   complaints. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2023,

title = {Effect of COVID-19 infection on mental health of medical students},

author = {Ariyan Khan and Mustafa Kagalwala and Minhajzafar Nasirabadi and Mazher Ali and Mehnaaz Sameera Arifuddin},

url = {https://www.tjima.org/journal/index.php/tjima/article/view/110},

doi = {10.52314/tjima.2023.v3i1.110},

year  = {2023},

date = {2023-06-28},

journal = {Telangana Journal of IMA},

volume = {3},

issue = {1},

pages = {13\textendash21},

abstract = {Background: Stressful environment in medical school often has a negative effect on students’ psychosocial well‐being and COVID-19 has a further additive effect on it. The COVID-19 pandemic is found to affect the mental health of the population. Undergraduate medical students are especially prone to mental health disorders and hence could be more vulnerable to the impact of the pandemic. An in‐depth understanding of how medical students experience psychological distress and coping is necessary for prospective students. 

Aim and Objective: To determine the effect of COVID-19 on mental health of medical students. 

Methods: A web-based cross-sectional study was carried out on 299 undergraduate medical students in the medical colleges of Telangana and Andhra Pradesh, India. They were divided into 4 groups based on whether the participants, their family members, both or none of them were affected with COVID-19 infection. The questionnaires provided to the participants in this study consisted of three components \textendash (i) the demographic information that required participants to provide their gender, age and year of study (ii) COVID-19 related questionnaire and (iii) Depression, Anxiety, and Stress Scale‐42 (DASS-42) items to measure the levels of psychological distress among participants. Chi square statistical test and One-way analysis of variance (ANOVA) were the statistical tools used in this study.

Results: It was observed that depression (χ=9.839, p=0.043) was found to be significant in participants who were not affected with COVID-19 infection. Statistically significant differences were observed in participants’ depression (χ=11.976, p=0.018) and stress (χ=9.839, p=0.043) levels whose family members were affected with COVID-19. One way ANOVA showed that anxiety levels (F(3,295)=4.267, p=0.006) was significantly higher when both participants and their family members (group 3) were affected with COVID-19 infection.

Conclusion: This study has shown that COVID-19 pandemic and subsequent lockdowns affected the mental health of young population.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bari_2023,

title = {Study of evaluation of functional outcome of compound fractures of tibia treated surgically by unreamed interlocking nail in adult patients},

author = {Mohammed Abdul Bari and Mohammed Akram and Bandela Venugopal and Mohmad Irfan Nagnur},

url = {https://healthcare-bulletin.co.uk/article?article_id=770\&download=true},

issn = {2042-4884},

year  = {2023},

date = {2023-06-21},

urldate = {2023-06-21},

journal = {European Journal of Cardiovascular Medicine},

volume = {13},

issue = {2},

pages = {1504-1521},

abstract = {Background and Objectives: Intramedullary interlocking nailing is currently considered the treatment of choice foropen(grade 1 and grade 2)tibial shaft fractures, with high rates of fracture union, advantages of early stabilization which decreases the morbidity and mortality rates in patients, allows early mobilization, reduces the incidence of infection,malunion,nonunion, or implant failure. This study is done to assess compound diaphyseal fractures of tibia and to evaluate the functional outcome of patients with open tibial shaft fracture treated with locked intramedullary nailing without reaming. Methods: Twenty adult patients of both sexes presented with open tibial shaft fractures to Princess Esra Hospital, Deccan College of medical sciences,Hyderabad who satisfies our inclusion criteria and are surgically fit are included in this study. All enrolled Patients were admitted from March 2020 to December 2021 were treated surgically with locked intramedullary interlocking nailing tibia without reaming and evaluated. Final assessment of functional outcome is done using JOHNER and WRUH’S Criteria. Results: The results of interlocking nail for fracture tibia without reaming were excellent in 15 patients (75%), good in 3 patients (15%) and fair in 2 patients (10%).  The average healing time was 20.13 weeks. In our study valgus deformity of 3 degrees (3 patients) and varus deformity of 3 degrees (1 patient) is seen. There were 1 superficial infection (5%), 2 patients with anterior knee pain (10%), 1 patient with delayed union (5%) and 1 patient with shortening of 1cm seen (5%). Conclusion: The method of treatment employing closed intramedullary interlocking nailing without reaming to stabilize open (type 1 and type 2) diaphyseal fractures of tibia is ideal because of its excellent and good results. The method has a long learning curve but with the excellent results. The advantages of rapid rehabilitation and relatively few complications serve to recommend it for wider use.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nasreen_2023,

title = {Seroprevalence of HPV infection and its association with HPV vaccination in adolescent girls in suburbs of Hyderabad},

author = {Humera Nasreen and Habib Khan Gulab Khan Pathan and Sarfaraz Ahmed Manzoor Ahmed},

url = {https://healthcare-bulletin.co.uk/article?article_id=758\&download=true},

doi = {10.5083/ejcm },

issn = {2042-4884},

year  = {2023},

date = {2023-06-16},

urldate = {2023-06-16},

journal = {European Journal of Cardiovascular Medicine},

volume = {13},

issue = {2},

pages = {1436-1439},

abstract = {Background: The prevalence of cervical cancer is increasing day by day. One of the best methods to prevent it is vaccination by HPV (Human Papilloma Virus) vaccine. Now a day’s more and more females are coming forward to take HPV vaccine. Sero-prevalence is one of the best methods to assess disease burden in the community Objectives: 1.  To study sero-prevalence of HPV in adolescent girls.  2. To study association of seroprevalence of HPV with HPV vaccination.  Method:  A community based cross sectional study was performed to assess the sero-prevalence of HPV at two private schools in suburban areas of Hyderabad, Telangana, in April 2022 to September 2022. Blood samples from 100 adolescent girls were collected \& analysed for HPV specific antibodies by ELISA. Results:  The sero-prevalence for HPV in the study group was low. There was a statistically significant HPV sero-positivity in all girls receiving HPV (<0.05). An association of sero-prevalence with age was analysed. There was no statistically significant association between age \& HPV antibodies (p>0.05 Conclusion:  The prevalence of HPV infection among adolescent girls is low and it is strongly associated with HPV vaccination.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mrudula_2023,

title = {Clinical outcome of established diagnostic and treatment modalities of COVID-19 associated myocarditis: a systematic review},

author = {Alla Sai Santhosha Mrudula and Pahel Agarwal and Roopeessh Vempati and Deekshitha Alla and Kavya Balusu and Suha Tarannum and Krish Patel and Sanjana Devaragudi and Devkumar Patel and Qamar Sultana and Kusum Paudel},

url = {https://journals.lww.com/annals-of-medicine-and-surgery/fulltext/2023/07000/clinical_outcome_of_established_diagnostic_and.48.aspx},

doi = {10.1097/ms9.0000000000000964},

issn = {2049-0801},

year  = {2023},

date = {2023-06-16},

urldate = {2023-06-16},

journal = {Annals of Medicine \& Surgery},

volume = {85},

issue = {7},

pages = {3583-3594},

publisher = {Ovid Technologies (Wolters Kluwer Health)},

abstract = {Background: Despite the significant research and development of COVID-19 diagnostic and therapeutic approaches, the virus still poses a concern, particularly to groups that are already vulnerable. Several individuals experienced cardiac problems like myocardial infarction, arrhythmia, heart failure, cardiomyopathy, myocarditis, and pericarditis after they had recovered from the infection. Early diagnosis and timely management of sequelae are part of the therapy. However, there are gaps in the knowledge of the diagnostic and definitive treatment options for COVID-19 myocarditis. This review focuses on myocarditis associated with COVID-19. Objective: This systemic review provides the most recent overview of myocarditis caused by COVID-19, including clinical manifestations, diagnostic techniques, available treatments, and outcomes. Methods: The PubMed, Google Scholar, and ScienceDirect servers were used to conduct a systematic search in compliance with the PRISMA guidelines. Boolean search terms included “(COVID-19)” OR “(COVID19)” OR “(COVID-19 VIRUS INFECTION)” AND “(MYOCARDITIS)”. The results were tabulated and analyzed. Results: A total of 32 studies, including 26 case reports and 6 case series, were included in the final analysis, and 38 cases of COVID-19-associated myocarditis were analyzed. Middle-aged men constituted the most affected population (60.52%). Dyspnoea (63.15%), chest pain or discomfort (44.73%), and fever (42.10%) were the prevalent presentations. ST-segment abnormalities were reported in 48.38% of cases on electrocardiography testing. Leucocytic infiltration (60%) was the frequent finding obtained on endomyocardial biopsy. Cardiac magnetic resonance imaging yielded myocardial oedema (63.63%), and late gadolinium enhancement (54.54%) as the most common findings. Reduced ejection fraction (75%) was the frequent result obtained on echocardiography. Corticosteroids (76.31%) and immunomodulators (42.10%) were the well-established in-hospital medications. Veno-arterial extracorporeal membrane oxygenation (35%) was the most common intervention used to support the treatment. The frequent in-hospital complications were cardiogenic shock (30.76%), followed by pneumonia (23.07%). The mortality rate was 7.9%. Conclusion: Early detection and timely management of myocarditis are essential to reduce the risk of developing further complications. It is crucial to emphasize the need to evaluate COVID-19 as a possible cause of myocarditis in populations that are young and healthy to avoid fatal consequences.},

key = {pmid37427189},

keywords = {},

pubstate = {published},

tppubtype = {article}

}