@article{Hazari_2024,

title = {Correlation of comorbidities and outcome in CAD patients: a novel TANGENTS score study},

author = {Mohammed Abdul Hannan Hazari and Kailas Laxman Rao and Bachi Tazneem and Sana Rafeeq and Syeda Rahmath Fatima and Summaya Jabeen and Kankan Kavya},

url = {https://mmsl.cz/corproof.php?tartkey=mms-000000-0435},

doi = {10.31482/mmsl.2024.009},

issn = {0372-7025},

year  = {2024},

date = {2024-06-18},

urldate = {2024-06-18},

journal = {Military Medical Science Letters},

volume = {93},

issue = {3},

pages = {XX-XX},

publisher = {Faculty of Military Health Sciences, University of Defence, Czech Republic},

abstract = {Background: Cardiovascular diseases (CVD) are influenced by various established risk factors, including the ratio of neutrophils to lymphocytes and platelets, which has been shown to be an independent risk factor for acute coronary syndrome (ACS). This study aims to create a new scoring system called TANGENTS that utilizes discrete parameters of risk factors and diagnostic parameters to analyze the outcome of coronary artery disease (CAD) patients with comorbidities, particularly Type 2 diabetes mellitus (T2DM).

Methods: We included 151 subjects (mean age 57.92 ± 23.86) who presented with ST-elevation and ST-depression on admission and were treated with heparin, clopidogrel, aspirin, and atorvastatin while undergoing all the necessary diagnostic tests. We obtained ECG and complete blood picture (CBP) results on admission, day 3, and day of discharge.

Results: ST-depression on ECG on day-1 was 0.35 and decreased to 0.30 on the day of discharge. ST-elevation on ECG on day-1 was -0.89 and decreased to -0.16 on the day of discharge. The average neutrophil-to-lymphocyte ratio (NPR) was 0.49, which was high in 144 patients. The mean NLR value was 5.52, indicating a correlation between high NLR values and the magnitude of current injury on admission.

Conclusion: The TANGENTS scoring system can be used as an early evaluation tool for CAD patients with comorbidities to manage and prevent further complications. It allows for progressive differentiation in the severity of clinical outcomes using all the parameters of the score, and the parameters creating the TANGENTS score scale were found to be reliable.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hyder_2024,

title = {Effect of smartphone usage during night time on sleep patterns of young adults: A cross-sectional observational study},

author = {Safa Hyder and Sudhir Shankar Mane and Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin},

url = {https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2024&month=April&volume=18&issue=4&page=CC01&id=19291},

doi = {10.7860/jcdr/2024/66874.19291},

issn = {0973-709X},

year  = {2024},

date = {2024-04-01},

urldate = {2024-01-01},

journal = {Journal of Clinical and Diagnostic Research},

volume = {18},

issue = {4},

pages = {CC01-CC06},

publisher = {JCDR Research and Publications},

abstract = {Introduction: Excessive smartphone usage among adolescents and young adults has been consistently linked to poor sleep. Moreover, smartphone overuse has been associated with daytime tiredness, longer sleeps latency, and reduced sleep duration. The significance of addressing poor sleep among adolescents and young adults is underscored by recent research linking it to adverse physical and psychological health outcomes, such as mood disturbances, impaired cognitive function, and increased risk incidence of hypertension and diabetes.

Aim: To evaluate the effects of smartphone usage on sleep quality among individuals using Pittsburgh Sleep Quality Index (PSQI) and hypnogram data.

Materials and Methods: In this cross-sectional observational study, sleep patterns were assessed using the PSQI questionnaire and Prime Nap sleep tracker app (version 1.1.4). The study was conducted by Deccan College of Medical Sciences, Hyderabad, Telangana, India. The data was collected in the form of a hypnogram and the study was conducted in the participants’ homes (under domicile conditions) in the city of Hyderabad, Telangana, India from March 2020 to April 2020. A total of 60 participants (both male and female) in the age group of 15-25 years were recruited and divided into two groups: one comprising 30 individuals with regular prolonged exposure to smartphone screens at night, and the other consisting of 30 individuals who experienced minimal or no smartphone exposure once they prepared to sleep. Descriptive statistics were applied to the collected data using Microsoft Excel and IBM Statistical Package for Social Sciences (SPSS) for Windows version 25.0.

Results: Adding up the average scores of the seven factors gives a global PSQI score from 0 to 21, with 0-4 indicating good sleep and 5-21 indicating poor sleep. Among those who used smartphones regularly at night time, 20 participants (66.67%) had PSQI score >5 and poor sleep quality, 24 participants (80%) had prolonged sleep latency, 18 participants (60%) had poor sleep duration, 27 participants (90%) had sleep disturbances, and 22 participants (73.33%) had increased daytime dysfunction. Hypnogram abnormalities were seen in >15 participants (50%) of subjects.

Conclusion: The prevalence of smartphone addiction is widely acknowledged in the medical literature, highlighting the need for its assessment, especially among adolescents and young adults. The study reveals that poor sleeping habits among participants were attributable either to a lack of awareness or neglect. By recognising the importance of adequate sleep, improvement in the quality of daily activities can be made by reducing daily screen time, consequently alleviating both physical and mental stress. Furthermore, the findings have implications for individuals whose work involves prolonged exposure to computer screens, especially during night time.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2023,

title = {Multisystem inflammatory syndrome in children (MIS-C) of Asian countries: a mini-literature review on its clinical characteristics and outcomes},

author = {Mehnaaz Sameera Arifuddin and Mohammed Abdul Hannan Hazari},

url = {https://esmed.org/MRA/mra/article/view/4070},

doi = {10.18103/mra.v11i7.2.4070},

issn = {2375-1924},

year  = {2023},

date = {2023-07-29},

urldate = {2023-07-29},

journal = {Medical Research Archives},

volume = {11},

issue = {7.2},

pages = {1-7},

abstract = {COVID-19 pandemic though has reached endemic levels in most of the countries, it has left an indelible mark on the healthcare systems across the world. One of the emerging challenges faced by physicians and researchers all around the world is the increased incidence of Multisystem inflammatory syndrome in children (MIS-C). Most of the research work conducted till date focusses on the pathophysiology, management and treatment of this syndrome. Multisystem inflammatory syndrome in children has been found to be a consequence of hyperactive immune system resulting from cytokine activation and release of immune complexes subsequent to COVID-19 infection. This condition is also associated with multisystem dysfunction which if not diagnosed early and not treated promptly, could result in an increased mortality among children. Most of the cases have been reported from European and American countries, but not many from Asia. 

This literature review provides for plausible reasons as to why the incidence of multisystem inflammatory syndrome in children has been less in Asian countries compared to the rest of the world. It also gives insights into the treatment protocols for multisystem inflammatory syndrome in children followed by hospitals in these countries and also highlights how different MIS-C is from Kawasaki disease in terms of clinical presentation since both these conditions share a common disease spectrum. This review also lists out the clinical features and treatment followed in such patients belonging to Asian countries.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2020,

title = {Effect of tea and coffee consumption on the blood pressure, pulse wave velocity and aortic pressures in young healthy individuals},

author = {Farah Fatima and Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin and Syed Abdul Tahreem},

url = {https://amphysiol.com/index.php/amp/article/view/v4i1.94611},

doi = {10.23921/amp.2020v4i1.94611},

issn = {2456-8422},

year  = {2020},

date = {2020-06-30},

urldate = {2020-06-30},

journal = {Annals of Medical Physiology},

volume = {4},

issue = {1},

pages = {3-11},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Caffeine present in tea and coffee, the most commonly used beverages, has been implicated to have long term effects on cardiovascular system. The aim of this study was to document the acute and chronic effects of tea and coffee consumption on blood pressure, pulse wave velocity and aortic pressures in young, healthy individuals. This observational study was conducted on 86 healthy MBBS student volunteers of both genders between the age group of 18-27 years. Cardiovascular parameters (heart rate, peripheral blood pressure, central blood pressure, pulse wave velocity, augmentation pressure) were measured using PeriScope™. Participants were divided into 3 groups based on their history of consuming tea/coffee/both/none. Data collected was analyzed using SPSS 17.0. ANOVA or Welsh test of equality of means was used for knowing the differences for scale variables. Paired sample t test was used to know the acute effect of coffee consumption among group 1 participants in a before-after design. In regular tea consumers, the bilateral brachial SBP, DBP and MAP were significantly higher than individuals who did not consume tea regularly; similar results in these parameters were also observed in regular coffee drinkers. However the lower limb arterial parameters were not markedly differently in tea/coffee group compared to non-drinkers. In both tea and coffee group, AoSP and AoDP were significantly higher than non-drinkers. Additionally, coffee drinking has acute stimulatory effects on CVS as evident by increase in peripheral and central vascular parameters.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sadaf_2020,

title = {Correlation of systolic and diastolic time intervals with demographic and anthropometric parameters in young adults},

author = {Sadiqua Sadaf and Mehnaaz Sameera Arifuddin and Mohammed Ziya Rahman and Mohammed Abdul Hannan Hazari and Syeda Bushra Quadri},

url = {https://www.j-pcs.org/article.asp?issn=2395-5414;year=2020;volume=6;issue=1;spage=23;epage=32;aulast=Sadaf;t=6},

doi = {10.4103/jpcs.jpcs_56_19},

issn = {2395-5414},

year  = {2020},

date = {2020-04-17},

urldate = {2020-04-17},

journal = {Journal of the Practice of Cardiovascular Sciences},

volume = {6},

issue = {1},

pages = {23-32},

publisher = {Wolters Kluwer - Medknow},

abstract = {Context: Dimensions of vasculature may vary with height, weight, and build of the individual. This may, in turn, influence the time intervals during cardiac cycle. Aims: The aim of this study was to correlate the systolic and diastolic time (DT) intervals (preejection period [PEP], ejection time [ET], upstroke time [UT], DT, pulse duration [PD], and ejection slope [ES]) of pulse waves recorded from all four limbs in relation to age, gender, weight, height, heart rate, and blood pressure and to compare these cardiac time intervals between individuals with or without parental history of hypertension. Settings and Design: Ninety-eight healthy MBBS students in the age group of 19–21 years were included. Subjects and Methods: Students' history and demographic data were noted. Anthropometric measurements were recorded. The measurement of peripheral arterial pressures (in all four limbs) and determination of cardiac intervals (PEP, ET, UT, DT, PD, and ES) was done by PeriScope™. Statistical Analysis Used: Data were analyzed using SPSS version 17.0. Results: Independent sample t-test showed statistically significant differences between genders with weight, height, waist circumference, and waist–hip ratio. Statistically significant differences existed between right arm systolic blood pressure, left arm systolic blood pressure, and left arm pulse pressure among males and females. Significant differences among males and females were observed in some of the cardiac time intervals. Mean arterial blood pressure recorded in all four limbs showed a significant negative correlation with right arm ES in males and left arm ES in females. Conclusion: Since gender, anthropometric parameters, and blood pressure influence cardiac time intervals, these should be adjusted for when deriving inference on left ventricular performance.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2020,

title = {Role of neutrophil to lymphocyte ratio (NLR) In conjunction with coronary artery involvement as a biomarker for the magnitude of current of injury, type of intervention and clinical outcomes in STEMI},

author = {Mohammed Abdul Hannan Hazari and K. Laxman Rao and Bachi Tazneem and Sara Sana Ayesha Khanum and Huma Quadri and Syeda Kehkashan Jabeen},

url = {https://journalajcr.com/index.php/AJCR/article/view/22},

year  = {2020},

date = {2020-01-17},

urldate = {2020-01-17},

journal = {Asian Journal of Cardiology Research},

volume = {3},

issue = {1},

pages = {1-7},

publisher = {OA Academic Press},

abstract = {Background: The potential prognostic biomarker—neutrophil to lymphocyte ratio (NLR) can be used to predict the severity of STEMI. We conducted an observational study using this parameter together with the extent of coronary artery involvement from coronary angiogram and magnitude of ST-elevation on ECG to determine the prognosis and the length of hospital stay. The effect of early reperfusion with thrombolysis was also observed.

Methods and Results: 30 subjects (age 56.43 ± 13.98), with ST-elevation on ECG at admission, treated with streptokinase and undergoing angiogram were taken for the study. Repeated ECGs and complete blood picture on admission day, day 3, day of discharge and on the follow-up day were obtained. Out of 30 subjects, 15 received thrombolysis out of which 12 (80%) survived compared to the other 15 subjects who presented late, out of which 10 (66.6%) survived. Mean ST-elevation on the day of admission, on day 3, day of discharge and on follow up was found to be 0.39 ± 0.12, 0.18 ± 0.12, 0.05 ± 0.07, 0.00 ± 0.00 respectively. NLR values on admission day were 7.89 ± 4.98, day 3 (6.24 ± 5.05), day of discharge (4.34 ± 2.74) and on follow up (1.71 ± 1.40) indicating association of higher NLR values with magnitude of current of injury. NLR values as high as 18.5 were observed in expired subjects. The length of hospital stay was found to be 6.43 ± 5.03 days.

Conclusion: There was a linear decrement in ST-segment resolution with a decrease in NLR and can be attributed to the natural course of disease and type of intervention provided. Nevertheless, the univariate correlation between ECG and NLR on various days of treatment was not significant.},

key = {AJCR.53641},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019e,

title = {Conflict of interest or competing interest: What is in the name?},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i4.94415},

doi = {10.23921/amp.2019v3i4.94415},

issn = {2456-8422},

year  = {2019},

date = {2019-12-31},

urldate = {2019-12-31},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {4},

pages = {29-30},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019d,

title = {Precision medicine in the era of live cell imaging},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i3.68136},

doi = {10.23921/amp.2019v3i3.68136},

issn = {2456-8422},

year  = {2019},

date = {2019-10-03},

urldate = {2019-10-03},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {3},

pages = {27-28},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019,

title = {A comparative study of central and peripheral arterial parameters in hypertensive patients on angiotensin receptor blockers and calcium channel blockers},

author = {K. Laxman Rao and Mohammed Abdul Hannan Hazari and Bachi Tazneem and Ahmed Abdul Aziz and Asiya Mohtesham and A. Afreen and Kethavath Priyanka},

url = {https://www.jhrr.org/article.asp?issn=2394-2010;year=2019;volume=6;issue=2;spage=76;epage=81;aulast=Rao;type=0},

doi = {10.4103/0028-3886.263243},

issn = {2394-2010},

year  = {2019},

date = {2019-07-23},

urldate = {2019-07-23},

journal = {Journal of Health Research and Reviews},

volume = {6},

issue = {2},

pages = {76-81},

publisher = {Wolters Kluwer - Medknow},

abstract = {Aims: Untreated or inappropriately managed hypertension (HTN) is a significant risk factor for all-cause morbidity and mortality due to its complications. For proper management of HTN, timely diagnosis and classification into appropriate category is crucial. According to hypertensive class category, pharmacological therapy can be initiated according to the national or international guidelines. Various antihypertensive medications have differential effects on peripheral and central arterial parameters. Our study was aimed at comparing the effects of two classes of antihypertensive drugs, i.e., angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs). Materials and Methods: Hypertensive patients on monotherapy – ARBs (Group 1, n = 35) and CCBs (Group 2, n = 35) – over the age of 18 years, belonging to both genders, were recruited. Results: Heart rate and peripheral and central arterial pressures were lower in Group 2 compared to Group 1; ankle brachial index and carotid-femoral pulse wave velocity were less in Group 1 in comparison with Group 2; but these differences were statistically not significant. Conclusions: We conclude that the two groups of drugs were equally effective in blood pressure reduction, both in central and peripheral arteries.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019c,

title = {Intracellular divalent ion oscillations: Is this the key phenomenon in rhythm generators?},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i2.54657},

doi = {10.23921/amp.2019v3i2.54657},

issn = {2456-8422},

year  = {2019},

date = {2019-06-30},

urldate = {2019-06-30},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {2},

pages = {19-20},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2019,

title = {Effects of cigarette smoking on erythrocyte sedimentation rate, platelet count, total and differential leucocyte counts in adult male smokers},

author = {Safia Sultana and Nabila Afsar and Mohammed Jawad and Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i1.35185},

doi = {10.23921/amp.2019v3i1.35185},

issn = {2456-8422},

year  = {2019},

date = {2019-03-28},

urldate = {2019-03-28},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {1},

pages = {14-18},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Smoking is one of the leading causes of death worldwide. Smokers have higher risk for coronary heart disease, atherosclerosis, acute myocardial infarction, hypertension, clotting disorders, inflammation, respiratory diseases, cancers, etc. A cigarette smoker is exposed to a number of harmful substances. In this study we hypothesized that smoking causes inflammatory reactions and induces hyperthrombic state in the body which may be reflected in erythrocyte sedimentation rate (ESR), total leucocyte count (TLC), differential leucocyte count (DLC) and platelet count values. The purpose of the study was to study the effects of cigarette smoking on erythrocyte sedimentation rate, total leucocyte count and platelet count in adult male smokers and to compare the results with non-smokers and to establish a relationship between the duration and quantity of smoking with the change in ESR, TLC, DLC and platelet count. A cross sectional study was conducted in the department of Pathology on 86 healthy male subjects (smokers=43 and non-smokers=43). ESR was estimated using Westergrens method. TLC, DLC and platelet counts were estimated using HORIBA Pentra ES60 autoanalyser. TLC and basophil counts were significantly higher in smokers than in non-smokers (p<0.05). The mean value of ESR was higher among smokers than non-smokers but it was statistically insignificant. Platelets counts showed no significant difference between smokers and non- smokers. No correlation was observed in various blood parameters and smoking (in pack years). We conclude that smoking initiates an inflammatory response as evidenced from raised TLC, monocyte and basophil counts.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2019b,

title = {Failing immune surveillance in humans: Repercussion of modern day lifestyles},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v3i1.38529},

doi = {10.23921/amp.2019v3i1.38529},

issn = {2456-8422},

year  = {2019},

date = {2019-03-27},

urldate = {2019-03-27},

journal = {Annals of Medical Physiology},

volume = {3},

issue = {1},

pages = {1-2},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kahkashan_2018,

title = {Variation in carotid-femoral pulse wave velocity, augmentation pressure and augmentation index during different phases of menstrual cycle},

author = {Nudrath Kahkashan and Mehnaaz Sameera Arifuddin and Mohammed Abdul Hannan Hazari and Safia Sultana and Farah Fatima and Syyeda Anees},

url = {https://amphysiol.com/index.php/amp/article/view/v2i3.10454},

doi = {10.23921/amp.2018v2i3.10454},

issn = {2456-8422},

year  = {2018},

date = {2018-11-28},

urldate = {2018-11-28},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {3},

pages = {27-32},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Physiological variation of estrogen and progesterone during menstrual cycle is well known.  They not only have an effect on blood pressure control, but also seem to have a role in regulating arterial compliance. This study was done to find out whether there are any changes in central arterial parameters during different phases of menstrual cycle. Thirty female  subjects  in the  age  group  of  18-22  years  with  normal,  regular menstrual  cycles  participated in this prospective observational study at our teaching hospital. Anthropometric parameters were recorded.  Blood pressure in all 4 limbs was recorded using cardiovascular risk analyzer-Periscope™ on Day 3rd to 5th (follicular phase), Day 12th to 14th (ovulation phase), Day 22nd to 24th (luteal phase) of their menstrual cycle. We collected blood samples during these three phases for estimation of estradiol and progesterone by ELISA technique. Analysis of variance and correlation statistics were done using SPSS 17.0 statistical software. No significant statistical changes were observed in systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, aortic systolic pressure, aortic diastolic pressure, aortic augmentation pressure, aortic index and pulse wave velocity during the three recorded phases of the menstrual cycle. There are many studies which correlate changes in peripheral artery blood pressure with different phases of menstrual cycle. But there is scarcity in data available which correlates central arterial pressures and arterial stiffness with natural hormonal variations in different phases of menstrual cycle. However, our results show that although there are subtle changes in blood pressure parameters along with estrogen and progesterone levels throughout the menstrual cycle, yet these were not statistically significant.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2018c,

title = {Hemorheology: Capturing the fluid dynamics of blood},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v2i3.15965},

doi = {10.23921/amp.2018v2i3.15965},

issn = {2456-8422},

year  = {2018},

date = {2018-11-28},

urldate = {2018-11-28},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {3},

pages = {25-26},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Naeem_2017b,

title = {Influence of glycemic control on platelet count in type II diabetics in absence of vascular complications},

author = {Kazi Husna Abdul Naeem and Mohammed Abdul Hannan Hazari and Farisa Khatoon and Farah Bahmed and Fariha Mohammedi },

url = {https://www.medpulse.in/Physiology/Article/Volume5Issue2/Physiology_5_2_4.pdf},

doi = {10.26611/103524},

issn = {2550-7613},

year  = {2018},

date = {2018-08-23},

urldate = {2018-08-23},

journal = {MedPulse International Journal of Physiology},

volume = {5},

issue = {2},

pages = {22-24},

abstract = {Background: Diabetes mellitus (DM) has attained a state of a global emergency with increasing prevalence worldwide. Altered thrombocyte morphology, count and function have been reported with diabetics. The present study aimed at determining the variation in platelet count with degree of glycaemic control in Type 2 diabetes patients. Methods: A total of 200 subjects were enrolled in the study of which 100 had HbA1c < 6.5 and 100 had HbA1c > 6.5. Sample for glucose estimation and platelet indices were collected and estimation were carried out by the auto-analyzer. The statistical evaluation was done using SPSS version 22. Student t- test was used for comparison between two variables namely HbA1c and platelet count. Results: Mean Platelet count was found to be significantly higher in patients with type -2 diabetes mellitus with HbA1C > 6.5 in comparison to patients having HbA1c < 6.5.(p < 0.01) Conclusion: This study revealed a higher mean platelet count for diabetics with poor glycaemic control than for diabetics with good glycaemic control. However, platelet counts in both groups were within the normal reference range for healthy individuals. Platelet count with other platelet indices like Mean Platelet Volume and Platelet Distribution Width are simple, effective and cheap tests that may be used to predict vascular complications in type 2 DM.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ali_2018,

title = {Prevalence of cuff hypertension among overweight and obese subjects},

author = {Syed Imran Ali and Farisa Khatoon and Mohammed Abdul Hannan Hazari and Nazia Uzma and Fariha Mohammedi},

url = {https://njppp.com/?mno=292752},

doi = {10.5455/njppp.2018.8.0308806032018},

issn = {2231-3206},

year  = {2018},

date = {2018-07-31},

urldate = {2018-07-31},

journal = {National Journal of Physiology, Pharmacy and Pharmacology},

volume = {8},

issue = {7},

pages = {1018-1021},

publisher = {ScopeMed},

abstract = {Background: Obesity is a lifestyle affliction, it is a side effect of poor habit and it can be reversed. Obesity is defined either by increased waist circumference, waist-hip ratio, and/or body mass index. Overestimation of blood pressure (BP) using an inappropriately small cuff is well documented. Using a BP cuff small for midarm circumference (AC) in obese patient's results in higher BP readings. Therefore, it was felt that there is a requirement to study the effect of different cuff sizes for different arm circumferences in obese individuals. The purpose of this study is to determine if cuff hypertension (HTN) is present in obese subjects.

Aims and Objective: To determine the presence of cuff HTN in obese subjects.

Materials and Methods: A total of 200 obese and 200 non-obese subjects between 20 and 50 years of age reporting to OHRC were included in the study. Systolic and diastolic BP were measured using a mercury sphygmomanometer with two cuff sizes, i.e., standard cuff 12 cm width (for MAC <32 cm) and large cuff 15 cm width (for MAC >32 cm).

Results: A total of 56 subjects were diagnosed as systolic HTN with standard cuff, i.e., 28% but with large cuff, it was only 24 subjects, i.e., 12% only, a difference of 16% between the prevalence of systolic HTN. Diastolic HTN diagnosed with standard cuff was 20% compared to large cuff 7.5%, a difference of 12.5%. The above differences are demonstrating 'cuff HTN' in the obese subjects.

Conclusion: In this study of 200 obese and 200 non-obese subjects, it was found that 'cuff HTN' is present in obese subjects.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2018b,

title = {Nanophysiology: Real-time phenomenal perspective in biology},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v2i2.302175},

doi = {10.23921/amp.2018v2i2.302175},

issn = {2456-8422},

year  = {2018},

date = {2018-06-30},

urldate = {2018-06-30},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {2},

pages = {17-18},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sayeed_2018,

title = {Immediate and delayed effect of Ramadan fasting on spirometry parameters},

author = {Adiba Sayeed and Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin},

url = {https://amphysiol.com/index.php/amp/article/view/v2i1.279619},

doi = {10.23921/amp.2018v2i1.279619},

issn = {2456-8422},

year  = {2018},

date = {2018-03-31},

urldate = {2018-03-31},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {1},

pages = {7-10},

publisher = {Quench Academy of Medical Education and Research (QAMER) Publishing House},

abstract = {Fasting in the month of Ramadan is an obligatory duty for muslims. Researchers have investigated health benefits of fasting and reported conflicting results. The purpose of this study was to determine the immediate and delayed effects of Ramadan fasting on spirometric parameters. 50 apparently healthy young adults aged between 17-27 years, belonging to both genders who fast during the month of Ramadan were enrolled for the study. Spirometric recordings were done at three different time points. First: 5-10 days before the start of Ramadan (Pre-Ramadan); second: within 10 days of the beginning of Ramadan fasting (Ramadan); third: within 7 days of the end of Ramadan (Post-Ramadan). There were no statistically significant differences between the three phases with respect to tidal volume (TV), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1), FEV1/FVC, peak expiratory flow rate (PEFR) and forced expiratory flow 25% to 75% (FEF25-27). To conclude, Ramadan fasting does not have any significant effect on pulmonary function tests as assessed by spirometry. Hence, the diagnosis and prognosis of a respiratory disorder made on spirometry findings are reliable and need no error correction if an individual is fasting.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hazari_2018,

title = {Target with-in target},

author = {Mohammed Abdul Hannan Hazari},

url = {https://amphysiol.com/index.php/amp/article/view/v2i1.275951},

doi = {10.23921/amp.2018v2i1.275951},

issn = {2456-8422},

year  = {2018},

date = {2018-03-31},

urldate = {2018-03-31},

journal = {Annals of Medical Physiology},

volume = {2},

issue = {1},

pages = {1-2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mohammedi_2018,

title = {Effect of nicotine on platelet function},

author = {Fariha Mohammedi and Mohammed Abdul Hannan Hazari and Farisa Khatoon and Kazi Husna Abdul Naeem and Syed Imran Ali},

url = {https://www.medpulse.in/Physiology/html_5_2_2.php},

doi = {10.26611/103522},

issn = {2550-7613},

year  = {2018},

date = {2018-02-10},

urldate = {2017-02-28},

journal = {MedPulse International Journal of Physiology},

volume = {5},

issue = {2},

pages = {13-16},

publisher = {MedPulse Publishing Corporation},

abstract = {Background: Tobacco is the dried and processed leaves of the plant Nicotiana tobacum that is widely cultivated and commercially grown in many countries of the world. In India, tobacco is taken in several other forms also, for example, Pan (betel quid), dried leaves (Patti), paste (Qiwam, Zarda), tobacco with lime (Khaini/Mawa). Its use is common in various parts of the world, including India and central Asia. An increase in the consumption of tobacco has been noticed among high school students, college students, and sports persons .This is immensely popular in all socio-economic states in India. It is viewed as especially ominous because of the ease , low expense of procurement, youth appeal, convenient shelf life and lack of social stigma. Despite the known health consequences of tobacco chewing‖ is not viewed by users as particularly dangerous and is considered less of a ―social evil‖ than smoking by much of the public. Previous reports have described long-term harmful effects of nicotine on various body parameters.. In view of the various pharmacological actions of nicotine and additives and the wide use in many regions and countries, chronic consumption  may affect the status of hematological parameters and further delineate the effects of tobacco use to health. The effect of smokeless tobacco use on health irrespective of the mode of consumption has been well documented. Objective: this study was conducted to determine hematological effects of nicotine on platelet count and its functions. Materials and Methods: This cross sectional study was done in the department of internal medicine Owaisi Hospital and Research Centre. A detailed assessment was done on 200 apparently healthy subjects, out of which 100 were tobacco chewers and 100 non chewers. Various parameters were recorded which include personal details, department of work, history of smoking , chewing tobacco, history of exposure to tobacco smoke, history of any chronic disease like diabetes mellitus and medication history. Hematological investigations done. Automated blood analyzer was used for estimation of platelet count Results: In tobacco chewers the following platelet parameters are higher than non-chewers. 1. Platelet count -Statistically significant. 2. PCT- not significant statistically.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}