@article{Jalees_2020,

title = {Adenosine deaminase and lactate dehydrogenase levels in serum and cerebrospinal fluid of patients with tuberculous meningitis},

author = {Syeda Shahana Jalees and Syed Tamkeen Hussain},

url = {https://www.ijcbr.in/journal-article-file/12281},

doi = {10.18231/j.ijcbr.2020.088},

issn = {2394-6369},

year  = {2020},

date = {2020-09-28},

urldate = {2020-09-28},

journal = {International Journal of Clinical Biochemistry and Research},

volume = {7},

issue = {3},

pages = {411-415},

abstract = {Meningitis is an active inflammatory condition of CNS. However prompt and precise aetiological diagnosis remains a challenge. Often a thorough CSF examination may not give a precise diagnosis. There is considerable urgency in establishing correct diagnosis in patients with tuberculous meningitis because specific therapy is most effective when initiated early in course of illness, delay may cause irreversible brain damage. Diagnosis often rests on circumstantial evidence such as history, typical CSF findings and other evidence for presence of tuberculosis such as acid fast bacilli in sputum, positive tuberculosis test and suspicious Chest x-ray. Under present study the role of enzymes such as adenosine deaminase and lactate dehydrogenase has been evaluated in diagnosis of tuberculous meningitis. Result of the study suggest that adenosine deaminase level in CSF and serum may be a useful parameter along with other routine estimations. The enzyme activity is high in disease such as tuberculosis where cellular mediated immunity is stimulated. Estimation of lactate dehydrogenase levels may not be a specific parameter for tuberculous meningitis this requires further studies in patients of meningitis with different aetiological diagnosis.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jalees_2017,

title = {Study of malondialdehyde and estimation of blood glucose levels in patients with diabetes mellitus with cataract},

author = {Syeda Shahana Jalees and M. Rosaline},

url = {https://www.ijcbr.in/journal-article-file/4718},

doi = {10.18231/2394-6377.2017.0074},

issn = {2394-6369},

year  = {2017},

date = {2017-07-11},

urldate = {2017-07-11},

journal = {International Journal of Clinical Biochemistry and Research},

volume = {4},

issue = {3},

pages = {319-323},

abstract = {Increased oxidative stress may contribute to development of complications in diabetes may result from over production of precursors to reactive oxygen radicals and/ or decreased efficiency of inhibitory scavenger systems. Senile diabetic cataract is one of the chronic complications of diabetes mellitus. The present study has been carried out in patients suffering with NIDDM (Type-2) with or without associated cataract. Hyperglycemia causes oxidative stress, as measured by malondialdehyde (MDA) (a lipid peroxidation product) is more in diabetic patients (370.80 n.mol/l) compared to the normal individuals (181.04 n.mol/l) whereas the oxidative stress in diabetics with cataract is significantly more (399.12 n.mol/l) than that in diabetics without complications. Attempts have been made under present study to estimate serum MDA levels as a marker of free radical stress against free radical injury.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}