@article{Kausar_2023,

title = {Blended learning as an interactive teaching learning method for medical undergraduates},

author = {Ruksana Kausar and Tahmeen Jameel and Raisa Faheem and Syed Wasif Hussain and Syyeda Anees},

url = {https://www.academicmed.org/Uploads/Volume5Issue3/69.%20[615.%20JAMP_MEDP]%20314-318.pdf},

doi = {10.47009/jamp.2023.5.3.69},

issn = {2687-5365},

year  = {2023},

date = {2023-04-03},

urldate = {2023-04-03},

journal = {International Journal of Academic Medicine and Pharmacy},

volume = {5},

issue = {3},

pages = {314-318},

abstract = {Background: Blended learning is the combination of online and face-to-face learning experience. In the recent years it has grown rapidly to be commonly used in education. Nonetheless, the effectiveness of this learning approach has not been completely quantitatively synthesized and evaluated in health education. Through this study we aimed to identify its strengths, weaknesses, from both student’ and lecturers’ viewpoint so that this innovative teaching and learning methods can help improve the students skills in critical thinking and academic achievement in medical education. Objective: The aim of the study was to assess the efficacy of blended learning compared to face-to-face learning. The objectives were to evaluate the perceptions of students on

blended learning, to evaluate the perceptions of faculty on blended learning and to evaluate the interdependencies of face to face and online learning in the blended learning course. Methods: The study design and sampling method was prospective interventional study, cluster sampling. The study included 150

students of phase 1 MBBS of 2021-2022 batch and faculty of biochemistry. The students were sensitized to the blended learning module-acid base balance. Consent of the students was taken and importance of research in

medical education was explained. The questionnaire used was adapted from the questionnaire in Sagarra and Zapata’s (2008) study. The questionnaire has two parts; one for the students and the other for the faculty. The one for the students has two sections; the first section contains 16 questions which students answered on a 5 point Likert scale. The second section includes one short answer question. The second part has 6 questions for the faculty which were also answered on a 5 point Likert scale. Results: This evaluation showed that blended learning model helped students improve the critical thinking and retaining power because traditional time/place barriers were removed. However, new barriers related to technology by both students and teachers

were noted. Conclusions: This study demonstrated different factors that affected the intention to use blended learning in undergraduate medical students and it has also highlighted that the blended way of study was more

helpful rather than purely face to face or online learning. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jameel_2019,

title = {Prevalence of auto-immune thyroid disease and anti-TPO antibodies in patients visiting out-patient ward for routine health check-up},

author = {Tahmeen Jameel and Mizba Khanam and Qursheed Sultana and Mohammed Ishaq},

year  = {2019},

date = {2019-10-01},

urldate = {2019-10-01},

journal = {IOSR Journal of Biotechnology and Biochemistry},

volume = {5},

issue = {5},

pages = {39-41},

abstract = {The objective of the present study was to investigate prevalence of Auto-Immune Thyroid Disease (AITD) and screening for anti-thyroid peroxide auto antibodies (anti-TPO) in subjects visiting out-patient ward of Department of Medicine (Princess Esra Hospital, Hyderabad). A total of 136 cases were included consecutively. Age and gender of the patients were recorded and serum was tested for Thyroid Profile and anti-TPO antibodies by Enzyme Linked ImmunoSorbent Assay (ELISA). The male to female ratio in 136 cases was 6.4%:93.6%. It was observed that 36 cases (26%) were found to be suffering from thyroid disease based on TSH, T3 and T4 levels of these 16 (11.7%) were hypothyroid, 7 (5%) were hyperthyroid cases. The remaining 10 (7%) cases were identified as having subclinical hypothyroidism. Of these cases 34 were found to be positive for anti-TPO auto-antibodies. The 2 negative cases were of hypothyroidism. Inordinately high proportion of females were found among AITD cases as well as among all the 136 cases selected for the study.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Faheem_2019,

title = {Measurement of urea and creatinine as a marker of renal function in Type 2 diabetes mellitus in patients with good glycemic control and poor glycemic control},

author = {Raisa Faheem and Tahmeen Jameel and Raiyan Ali Afrooz and Syed Junaid Ahmed},

url = {https://saudijournals.com/media/articles/SIJB_29_234-236.pdf},

doi = {10.36348/SIJB.2019.v02i09.002 },

issn = {2616-8650},

year  = {2019},

date = {2019-09-30},

urldate = {2019-09-30},

journal = {Scholars International Journal of Biochemistry},

volume = {2},

issue = {9},

pages = {234-236},

abstract = {Diabetes is a common cause of end stage renal disease and approximately 20 to 30% of all diabetics will develop

nephropathy. Diabetic nephropathy is characterised by abnormal renal function with reduction of glomerular filtration and rise in the level of Serum Urea and Creatinine. The study was conducted at Princess Esra Hospital, Deccan College of Medical Sciences. Patients with Dm in the age group 35 Yrs – 55 Yrs and controls also of the same age group Glycosylated Haemoglobin (Hb A1C) was done to categorise patients into two groups. Patients with good glycemic control having HbA1c<6-7%, Studies have demonstrated that the complications of diabetes can be delayed or prevented if HbA1c can be kept between 6-7%. The other group of patients were having poor glycemic control with HbA1c above 8%. The following parameters were included in the study FBS, PLBS, HbA1cm Urea and Creatinine. These parameters were estimated in normal (controls) and diabetics (with good glycemic control) and diabetics (with poor glycemic control). It was found that the blood sugar, blood urea and serum creatinine levels were significantly higher in diabetic patients with poor glycemic control compared to diabetic patients with good glycemic control. Strong relationship of blood urea and serum creatinine levels was found with blood sugar and HbA1c levels. Blood urea, serum creatinine blood sugar along with HbA1c would be helpful to monitor the diabetes patients to assess renal function.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jameel_2019,

title = {Prevention of complications in Type II diabetes mellitus by measuring glycated hemoglobin, 24 hours urinary protein and protein creatinine ratio and fundus examination},

author = {Tahmeen Jameel and Syed Mahmood Ahmed and Aiman Mahmood and Mahbub Unnisa},

url = {https://www.iosrjournals.org/iosr-jbb/papers/Volume%205,%20Issue%204/C0504012022.pdf},

doi = {10.9790/264X-0504012022},

issn = {2455-264X},

year  = {2019},

date = {2019-07-16},

urldate = {2019-07-16},

journal = {IOSR Journal of Biotechnology and Biochemistry},

volume = {5},

issue = {4},

pages = {20-22},

abstract = {The measurement of glycated hemoglobin, 24 hours urinary protein and protein creatinine ratio serves as an important index in the monitoring of diabetes patients to prevent the complications. Screening patients for Retinopathy is again very important. The cause of diabetic complication is not known. Major emphasis has been placed on the polyol pathway where in glucose is reduced to sorbitol by the enzyme aldolase reductase with reduced NADPH as the electron donating coenzyme. Sorbitol molecule is oxidized to fructose by the enzyme Sorbitol dehydrogenase and reduced NAD+ . Sorbitol appears to function as a tissue toxin and has been implicated in the pathogenicity of retinopathy, neuropathy and cataract. Among the clinically important secondary microvascular complications of diabetes, kidney as the target organ represents a health problem of enormous social cost. Nephropathy like other diabetic complications is probably influenced by genetic factors. 35% of NIDDM patients develop nephropathy. Diabetic nephropathy is duration dependent and extends over many years before becoming clinically evident. Persistent proteinuria appears to predict evidence of kidney damage. Proteinuria is the most widely accepted sign of diabetic nephropathy. Spot protein, creatinine ratio would be more accurate and less time consuming. Diabetic nephropathy is leading cause of morbidity and premature mortality in diabetes subjects. Diabetic nephropathy has an insidious onset with increase in glycated hemoglobin before the appearance of microalbuminuria.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jameel_2017,

title = {Altered activity of lecithin cholesterol acyl transferase enzyme and high density lipoprotein in type 2 diabetes mellitus},

author = {Tahmeen Jameel and Raisa Faheem and Aiman Mahmood and Afnan Ali Afrooz},

url = {https://www.medpulse.in/Biochemistry/Article/Volume4Issue2/Biochem_4_2_1.pdf},

doi = {10.26611/1002421},

issn = {2550-763X},

year  = {2017},

date = {2017-10-26},

urldate = {2017-10-26},

journal = {MedPulse International Journal of Biochemistry},

volume = {4},

issue = {2},

pages = {29-31},

abstract = {An important enzyme in modulating plasma HDL levels is cholesterol acyl transferase (LCAT) which is responsible for the formation of most of the cholesterol esters (CE) present in human plasma. This enzyme catalyses the transfer of fatty acid from the Sn-2 position of the lecithin to the free hydroxyl group of cholesterol. It utilizes linoleate for the esterification of cholesterol in preference to the other fatty acids. Thus the enrichment of the linoleate content of plasma lecithin which accompanies ingestion of a poly unsaturated fat diet leads to an increase in the proportion of cholesterol linoleate in plasma. The physiological substrate for LCAT is probably nascent HDL. The enzyme activity is dependent on apoA-1 and in inhibited by apoA-2. Thus the maturing HDL particles contain mainly esterified cholesterol which having been rendered non diffusible are trapped in the HDL and then are transferred to the liver to undergo catabolism. Present studies have been carried out on diabetic patients with good glycaemic control and diabetics with poor glycaemic control and compared with normal control group. HDL cholesterol levels in diabetic patients with good and poor glycaemic control were significantly lower than the normal control group. LCAT in diabetic patients with good and poor glycaemic control were significantly lower than the normal control group. However HDL cholesterol level and LCAT activity in diabetic patients with poor glycaemic control was still lower this supports the observation that coronary artery disease (CAD) is 2-4 times higher in diabetes than non diabetes.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jameel_2017,

title = {Study of plasma fibrinogen in diabetes mellitus with complications},

author = {Tahmeen Jameel and Raisa Faheem and Syyeda Anees},

url = {https://www.medpulse.in/Biochemistry/Article/Volume4Issue1/Biochem_4_1_2.pdf},

doi = {10.26611/1002412},

issn = {2550-763X},

year  = {2017},

date = {2017-10-23},

journal = {MedPulse International Journal of Biochemistry},

volume = {4},

issue = {1},

pages = {5-7},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jameel_2014,

title = {Estimation of glycated hemoglobin in Type 2 diabetes mellitus},

author = {Tahmeen Jameel and Syed Mahmood Ahmed },

url = {https://www.cibtech.org/J-Innovative-Research-Review/Publications/2014/Vol-2-No-1/JIRR-05-010-TAHMEEN-ESTIMATION-MELLITUS.pdf},

issn = {2347-4424},

year  = {2014},

date = {2014-01-01},

urldate = {2014-01-01},

journal = {International Journal of Innovative Research and Review},

volume = {2},

issue = {1},

pages = {29-34},

abstract = {The study on measurement of glycated haemoglobin levels serves as an important index in the diagnosis of diabetes and also monitoring of diabetes patients to prevent the complications. The cause of diabetic complication is not known. Major emphasis has been placed on the polyol pathway where in glucose is reduced to sorbitol by the enzyme aldose reductase with reduced NADPH as the electron donating coenzyme. Sorbitol molecule is oxidised to fructose by the enzyme sorbitol dehydrogenase and reduced NAD+. Sorbitol appears to function as a tissue toxin and has been implicated in pathogenesis of retinopathy, neuropathy, cataract and aortic diseases. A second mechanism of potential pathogenetic importance is glycation of proteins. Glycation is non enzymatic addition of hexoses to proteins and glycosylation is enzymatic addition. This chemical reaction is the linkage between a reducing sugar and a receptive amino acid. It was first described in relation to food proteins (Millard, 1913). It has been shown that the difference in ionic charge between HBA1c and ordinary adult haemoglobin was due to addition of a glucose molecule to the amino terminal valine of the beta chain via an aldimine linkage which then underwent an Amadori rearrangement to form a more stable and virtually irreversible ketamine product (Bookchin, 1968; Bunn, 1975). The logical culmination of these findings was the hypothesis that in diabetes the level of glycosylated haemoglobin HBA1c or HBA1 would be proportional to the time averaged blood glucose level in the previous 7-8weeks, a period approximating to the half life of the average red blood cells. Normal glucose produces a normal amount of glycated haemoglobin. In diabetes mellitus higher amount of glycated haemoglobin indicates poorer control of blood glucose level. Fasting plasma glucose and glycated haemoglobin was estimated and based on the results the subjects were classified into three groups. Group I: Normal control non diabetic subjects; Group II: DM with good glycaemic control; Group III: DM with poor glycaemic control; Group II and group III patients were evaluated for complications by including lipid profile, tests for protein in urine and fundus examination. It was found that one or more complications were more predominant in Group III than in group II subjects. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Faheem_2013,

title = {Study of serum adenosine deaminase activity (ADA) in diabetes mellitus with complications},

author = {Raisa Faheem and Tahmeen Jameel },

url = {https://www.cibtech.org/J-LIFE-SCIENCES/PUBLICATIONS/2013/Vol_3_No_3/JLS-20-18...AFROZE...%20STUDY...%20COMPLICATIONS.pdf},

issn = {2231– 6345},

year  = {2013},

date = {2013-01-01},

urldate = {2013-01-01},

journal = {Indian Journal of Fundamental and Applied Life Sciences},

volume = {3},

issue = {3},

pages = {142-149},

abstract = {Diabetes mellitus is a complex syndrome characterized by hyperglycemia, leading to vascular complications such as retinopathy, neuropathy and macrovascular disease like atherosclerosis. Patients with diabetes with complications and without complications are taken up for the study. The parameter serum Adenosine Deaminase, Activity (ADA) is considered, which is helpful in understanding the predisposing factors and the assessment of these patients to develop complications. The present study reveals that serum ADA is found to be raised in diabetic patients without complications while it is similar to control group with complications. This indicates that increased susceptibility of diabetes to develop a variety of bacterial and fungal infection may not be due to immune deficiency.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jameel_2013,

title = {Estimation of lecithin cholesterol acyl transferase activity and high density lipoprotein cholesterol in type 2 diabetes mellitus},

author = {Tahmeen Jameel and Syed Mahmood Ahmed },

url = {https://www.cibtech.org/J-MEDICAL-SCIENCES/PUBLICATIONS/2013/Vol_3_No_3/JMS-14-022-TAHMEEN-%20ESTIMATION-%20MELLITUS.pdf},

issn = {2277-2103},

year  = {2013},

date = {2013-01-01},

urldate = {2013-01-01},

journal = {International Journal of Basic and Applied Medical Sciences},

volume = {3},

issue = {3},

pages = {100-109},

abstract = {An important enzyme in modulating plasma HDL levels is lecithin cholesterol acyl transferase (LCAT) which is responsible for the formation of most of the cholesterol esters (CE) present in human plasma. This enzyme catalyses the transfer of fatty acid from the Sn-2 position of the lecithin to the free hydroxyl group of cholesterol. It utilizes linoleate for the esterification of cholesterol in preference to the other fatty acids. Thus the enrichment of the linoleate content of plasma lecithin which accompanies ingestion of a poly unsaturated fat diet leads to an increase in the proportion of cholesterol linoleate in plasma. The physiological substrate for LCAT is probably nascent HDL. The enzyme activity is dependent on apoA-1 and is inhibited by apoA-2. Thus the maturing HDL particles contain mainly esterified cholesterol which having been rendered non diffusible are trapped in the HDL and then are transferred to the liver to undergo catabolism. Present studies have been carried out on diabetic patients with good glycaemic control and diabetics with poor glycaemic control and compared with normal control group. HDL cholesterol levels in diabetic patients with good and poor glycaemic control were significantly lower than the normal control group. LCAT in diabetic patients with good and poor glycaemic control were significantly lower than the normal control group. However HDL cholesterol level and LCAT activity in diabetic patients with poor glycaemic control was still lower this supports the observation that coronary artery disease (CAD) is 2-4 times higher in diabetes than in non diabetes.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jameel_2013b,

title = {Estimation of lipid profile in type 2 diabetes mellitus},

author = {Tahmeen Jameel and Raisa Faheem and Syed Mahmood Ahmed},

url = {https://www.cibtech.org/J-MEDICAL-SCIENCES/PUBLICATIONS/2013/Vol_3_No_3/JMS-05-006-%20TAHMEEN-%20ESTIMATION-%20MELLITUS.pdf},

issn = {2277-2103},

year  = {2013},

date = {2013-01-01},

urldate = {2013-01-01},

journal = {International Journal of Basic and Applied Medical Sciences},

volume = {3},

issue = {3},

pages = {24-38},

abstract = {Impaired Lipid Metabolism resulting from uncontrolled hyperglycemia has been implicated in cardiovascular complications in diabetes patients. In the present study the impact of glycaemic control on the lipid profile of diabetic patients is examined. Lipoprotein levels are measured in non-diabetic persons and NIDDM (Type 2 DM) patients with good control and poor control of Diabetes mellitus (DM). The present study also reveals that reducing LDL cholesterol is beneficial in reducing CAD risk and lowering of LDL cholesterol being a primary target in the prevention of CAD.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nasreen_2012,

title = {Glutamate decarboxylase and GABA aminotransferase levels in different regions of rat brain on the onset of leptazol induced convulsions},

author = {Zahida Nasreen and Tahmeen Jameel and Ashfaq Hasan and Parveen Naimath and B. Sadasivudu},

url = {https://link.springer.com/article/10.1007/s11064-011-0603-2},

doi = {10.1007/s11064-011-0603-2},

issn = {0364-3190},

year  = {2011},

date = {2011-09-21},

urldate = {2011-09-21},

journal = {Neurochemical Research},

volume = {37},

issue = {1},

pages = {202-204},

abstract = {The activities of Glutamate decarboxylase (GAD) and Gamma aminobutyric acid (GABA) were studied in three regions of rat brain in heightened neuronal activity resulting in convulsions by Leptazol. These enzymes were studied in preconvulsive, convulsive and post convulsive phases. The activity of GAD decreases significantly in the preconvulsive phase in all the three regions of brain followed by a significant increase during the convulsive and post convulsive phase in cerebral cortex and cerebellum. The activity of GABA-T decreases maximal during the preconvulsive phase followed by convulsive phase. The activity of this enzyme tended to increase to control values when the postconvulsive phase was reached. Therefore, it is suggested that the concomitant decrease of GAD activity and GABA concentration, is probably an important factor in the onset of convulsions.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}