@article{Vadthya_2026,

title = {Laparoscopic versus open cholecystectomy in gangrenous cholecystitis: a retrospective comparative study},

author = {Ganesh Vadthya and Srikanth N. Jarupla and Ajit K. Naik and Rahul Tiwari and Anil Managutti and Seema Gupta},

url = {https://assets.cureus.com/uploads/original_article/pdf/467424/20260305-335444-dg373w.pdf},

doi = {10.7759/cureus.104682},

issn = {2168-8184},

year  = {2026},

date = {2026-03-04},

urldate = {2026-03-04},

journal = {Cureus},

volume = {18},

issue = {3},

pages = {e104682},

abstract = {Introduction: Gangrenous cholecystitis (GC) is a severe form of acute cholecystitis associated with increased operative difficulty and postoperative morbidity. Although open cholecystectomy is traditionally preferred, advances in minimally invasive surgery have expanded the role of laparoscopy. However, the optimal surgical approach to GC remains controversial. This study aimed to compare the perioperative and postoperative outcomes of laparoscopic and open cholecystectomy in patients with GC.

Materials and methods: This retrospective observational study was conducted at the Department of General Surgery at Deccan College of Medical Sciences, a tertiary care cente in Hyderabad, India. It included adult patients with intraoperatively confirmed GC who underwent laparoscopic or open cholecystectomy at a tertiary care center over a two-year period. Demographic data, operative parameters, intraoperative complications, postoperative morbidity, and length of hospital stay were analyzed and compared between groups.

Results: Seventy-nine patients were included, of which 34 underwent laparoscopic cholecystectomy and 45 underwent open cholecystectomy. Baseline demographic and clinical characteristics were comparable between the groups. The mean operative time was significantly longer in the laparoscopic group (98.5 ± 25.4 min) than in the open group (86.2 ± 22.1 min; p = 0.023). The intraoperative complication rates were similar (p = 0.87). Conversion to open surgery occurred in eight (23.5%) laparoscopic cases. The total number of postoperative complications showed a non-significant reduction following laparoscopic cholecystectomy (p = 0.052), not meeting the predefined threshold for statistical significance (p < 0.05). The median hospital stay was shorter in the laparoscopic group (6 vs. 8 days, p = 0.039).

Conclusion: Laparoscopic cholecystectomy is a safe and feasible option for GC, offering shorter hospital stay despite a longer operative time. A laparoscopic-first approach, with a low threshold for conversion, is recommended for appropriately selected patients.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jarupla_2026,

title = {Comparative outcomes of transabdominal preperitoneal and totally extraperitoneal laparoscopic inguinal hernia repair: a retrospective cohort study},

author = {Srikanth N. Jarupla and Ganesh Vadthya and Ajit K. Naik and Heena Dixit and Prashant Pillai and Anil Managutti and Seema Gupta},

url = {https://assets.cureus.com/uploads/original_article/pdf/466996/20260301-75314-70i5kz.pdf},

doi = {10.7759/cureus.104487},

issn = {2168-8184},

year  = {2026},

date = {2026-03-01},

urldate = {2026-03-01},

journal = {Cureus},

volume = {18},

issue = {3},

pages = {e104487},

abstract = {Introduction: Laparoscopic inguinal hernia repair is widely performed using either the transabdominal

preperitoneal (TAPP) or totally extraperitoneal (TEP) approach. Although both techniques are established,

uncertainty persists regarding their relative perioperative and postoperative outcomes in routine clinical

practice. The aim of the present study was to compare operative parameters, postoperative recovery,

complication rates, and short-term outcomes between TAPP and TEP laparoscopic inguinal hernia repair.

Materials and methods: This retrospective cohort study included 100 adult patients who underwent elective

laparoscopic inguinal hernia repair between August 2021 and April 2023. Patients were equally divided into

TAPP (n = 50) and TEP (n = 50) groups. Demographic characteristics, operative details, postoperative pain,

length of hospital stay, intraoperative conversion, complications, and follow-up outcomes were analyzed.

Continuous variables were compared using independent samples t-tests, and categorical variables were

analyzed using Fisher's exact or chi-squared tests.

Results: Baseline demographic and hernia-related characteristics were comparable between the groups. A

significantly higher intraoperative conversion rate was observed in the TEP group. Operative time,

postoperative pain scores, and hospital stay did not differ significantly between techniques. Rates of short-

term complications, including seroma, infection, and urinary retention, were similar. Short-term outcomes,

including recurrence and chronic groin pain, showed no statistically significant differences during follow-

up.

Conclusion: Both TAPP and TEP laparoscopic inguinal hernia repairs demonstrated comparable safety and

effectiveness. However, the higher conversion rate associated with TEP highlights its technical complexity.

Technique selection should be guided by surgeon experience, patient factors, and institutional expertise.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Atharuddin_2026,

title = {An observational study to assess the effectiveness of intermittent vs continuous negative pressure wound therapy in the healing of diabetic foot ulcers},

author = {Athar Mohammed Atharuddin and Yasaswi Ponnapalli},

url = {https://app.theinternationalmedicine.com/public/testarticle/pdfFile-1771181250710-421183918.pdf},

doi = {10.61336/im/26-2-19},

issn = {1468-3814},

year  = {2026},

date = {2026-02-14},

urldate = {2026-01-28},

journal = {International Journal of Medicine},

volume = {8},

issue = {1},

pages = {127-133},

abstract = {BBackground: Diabetic foot ulcers (DFUs) are among the most serious complications of diabetes mellitus and are associated with delayed wound healing, infection, prolonged hospitalization, and increased risk of lower-limb amputation. Negative pressure wound therapy (NPWT) has emerged as an effective adjunct in DFU management. While continuous NPWT is commonly used, intermittent NPWT has been proposed to enhance wound healing through improved tissue perfusion and cellular stimulation. However, comparative evidence between these two modalities remains limited. Aim of the study was to compare the effectiveness of intermittent versus continuous negative pressure wound therapy in the healing of diabetic foot ulcers with respect to wound contraction, granulation tissue formation, wound closure time, and duration of hospital stay. Materials and Methods: This prospective observational study was conducted over 18 months at a tertiary care center. Sixty patients with Wagner grade 1 and 2 diabetic foot ulcers were enrolled and divided into two groups: Group A (continuous NPWT, n = 30) and Group B (intermittent NPWT, n = 30). After surgical debridement, NPWT was applied at −75 to −125 mmHg either continuously (Group A) or intermittently (1 hour every 3 hours; Group B). Patients were followed up to 12 weeks. Outcomes assessed included wound contraction percentage, time to wound closure, granulation tissue formation, and length of hospital stay. Statistical analysis was performed using IBM SPSS version 24. Results: Baseline characteristics were comparable between the two groups. Wound healing at 12 weeks was higher in the intermittent NPWT group compared to the continuous NPWT group (86.67% vs 73.33%). Intermittent NPWT demonstrated significantly greater wound contraction at 6 weeks (76.63% vs 68.45%, p = 0.001) and 12 weeks (93.84% vs 88.16%, p = 0.01). Mean wound closure time was significantly shorter in the intermittent group (72.65 ± 14.92 days) compared to the continuous group (82.71 ± 16.75 days; p = 0.0001). The duration of hospital stay was slightly shorter in the intermittent group but did not reach statistical significance. Conclusion: Intermittent NPWT is more effective than continuous NPWT in promoting wound contraction and accelerating wound closure in diabetic foot ulcers. It represents a superior modality for optimizing DFU healing outcomes.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2025h,

title = {Evaluation of emergency laparotomy for ileocaecal emergencies a clinicopathology, prognosis, and outcome based study},

author = {Arshiya Fatima and Zaid Mazhar Syed and Syed Mohammed Sajjad Husayni},

url = {https://jccpractice.com/article/evaluation-of-emergency-laparotomy-for-ileocaecal-emergencies-a-clinicopathology-prognosis-and-outcome-based-study-1712/},

doi = {10.61336/jccp/25-11-129},

issn = {2457-7200},

year  = {2025},

date = {2025-12-11},

urldate = {2025-12-11},

journal = {Journal of Contemporary Clinical Practice},

volume = {11},

issue = {11},

pages = {1034-1039},

abstract = {Background and Objectives: Ileocaecal emergencies, such as perforation, blockage, and inflammatory or viral diseases, continue to be prevalent causes of acute abdomen necessitating immediate laparotomy. These disorders are linked to considerable morbidity and mortality, particularly when diagnosis or management is postponed. The current study sought to assess the clinicopathological characteristics, surgical findings, postoperative complications, prognosis, and overall outcomes of patients receiving emergency laparotomy for ileocecal crises. Materials and Methods: Most of the 60 patients were men, and the age group with the most cases was 30 to 50 years old. 95% of the symptoms were stomach pain, followed by vomiting (72%) and stomach distension (60%). The most common causes of ileocaecal emergencies were ileal perforation (40%), typhoid perforation (25%), intestinal blockage (20%), and tuberculosis-related pathology (15%). Loop ileostomy, resection with anastomosis, and primary closure were some of the most common methods used. 35% of patients had complications after surgery, with infections at the surgery site being the most prevalent. Results: Among the 60 patients, the majority were males, with the highest incidence in the 30–50-year age group. The most common presenting symptoms were abdominal pain (95%), vomiting (72%), and abdominal distension (60%). The leading causes of ileocaecal emergencies were ileal perforation (40%), typhoid perforation (25%), intestinal obstruction (20%), and tuberculosis-related pathology (15%). Primary closure, resection with anastomosis, and loop ileostomy were the commonly performed procedures. Postoperative complications occurred in 35% of patients, with surgical site infection being the most frequent. The overall mortality rate was 10%, primarily associated with delayed presentation, septic shock, and extensive peritoneal contamination. Early surgical intervention significantly improved outcomes. Conclusion: Ileocaecal emergencies remain significant clinical issues necessitating rapid diagnosis and quick surgical intervention to mitigate morbidity and mortality. Early presentation, vigorous resuscitation, and suitable surgical interventions are crucial factors influencing positive outcomes. Improving perioperative care and making early referral systems stronger can make patients' chances of getting better even better.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Husayni_2025,

title = {Accuracy of pre-operative scoring in predicting difficulty level of laproscopic cholecystectomy},

author = {Syed Mohammed Sajjad Husayni and Arshiya Fatima and Zaid Mazhar Syed},

url = {https://jccpractice.com/article/accuracy-of-pre-operative-scoring-in-predicting-difficulty-level-of-laparoscopic-cholecystectomy--1706/},

doi = {10.61336/jccp/25-11-127},

issn = {2457-7200},

year  = {2025},

date = {2025-12-09},

urldate = {2025-12-09},

journal = {Journal of Contemporary Clinical Practice},

volume = {11},

issue = {11},

pages = {997-1008},

abstract = {Background: Difficult laparoscopic cholecystectomy (DLC) remains a major intraoperative challenge, especially in resource-limited settings where early identification of high-risk cases is crucial for minimizing bile duct injury, operative delays, and conversion to open procedures. Although several predictive systems exist, most are derived from mixed populations or rely on subjective parameters, limiting their applicability in newly developing laparoscopic units. Objective: To validate a preoperative scoring system for predicting difficult laparoscopic cholecystectomy and to establish a modified intraoperative grading score incorporating comprehensive operative parameters. Methods: A prospective cross-sectional study was conducted on 150 patients undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis. Preoperative variables were scored using a modified predictor scale, while intraoperative difficulty was graded using an expanded objective score incorporating adhesions, gallbladder distension, BMI, prior surgical scarring, bile/stone spillage, ductal injury, conversion, and ligature method. Diagnostic performance was assessed using sensitivity, specificity, predictive values, and ROC analysis. Multivariate logistic regression identified independent predictors of difficult LC. Results: Based on intraoperative scoring, 28.7% of patients experienced moderate–severe difficulty. The preoperative score demonstrated excellent discriminatory ability (Sensitivity 94.8%, Specificity 96.2%, AUC 0.945). The intraoperative score also performed strongly (Sensitivity 95.8%, Specificity 98.1%, AUC 0.939). Independent predictors of difficult LC included age ≥50 years, history of acute cholecystitis, BMI >30, palpable gallbladder, impacted stone, adhesions burying the gallbladder, dissection time >90 min, bile/stone spillage, and suture ligature requirement. Conclusion: Both the preoperative and modified intraoperative scoring systems demonstrated high diagnostic accuracy and reliability for predicting difficult LC. These scoring tools are simple, objective, reproducible, and particularly valuable in resource-limited settings for optimizing surgical scheduling, assigning appropriate expertise, improving patient counseling, and reducing intraoperative complications. Implementation of these scores may enhance safety and standardize difficulty assessment across surgical teams.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Qamesa_2025,

title = {A comparative study of conservative and surgical intervention in the management of venous leg ulcer},

author = {Ubhatullah Qamesa and T. Naga Raja Ravi Kishore and Satya Srividya Kalluri},

url = {https://healthcare-bulletin.co.uk/article/a-comparative-study-of-conservative-and-surgical-intervention-in-the-management-of-venous-leg-ulcer-4488/},

doi = {10.61336/ejcm/25-11-34},

issn = {2042-4884},

year  = {2025},

date = {2025-11-15},

urldate = {2025-11-15},

journal = {European Journal of Cardiovascular Medicine},

volume = {15},

issue = {11},

pages = {229-235},

abstract = {Background:: Venous leg ulcers are chronic, recurring wounds of the lower limbs caused by venous hypertension and valvular incompetence. They represent a major cause of morbidity and impaired quality of life. Although conservative measures such as compression therapy and wound care promote healing, recurrence is common. Surgical correction of venous reflux may offer better long-term outcomes. This study aimed to compare conservative and surgical management in the treatment of venous leg ulcers with respect to healing rate, ulcer size reduction, and duration of recovery. Aim of the study was to evaluate and compare the efficacy of conservative and surgical management in venous ulcer healing, analyze changes in ulcer size at 1 and 2 months, and assess overall healing at 6 months. Materials and Methods: A prospective comparative study was conducted on 60 patients with venous leg ulcers, divided into two groups of 30 each. Group I (Conservative) received regular wound dressing, compression therapy, and sclerotherapy. Group II (Surgical) underwent ligation and stripping of incompetent veins or subfascial perforator ligation. Parameters such as ulcer size, duration, site, and healing status were recorded at baseline, 1 month, 2 months, and 6 months. Statistical analysis was done using unpaired t-test, Chi-square test, and ANOVA, with p < 0.05 considered significant. Results: The mean age was 58.4 ± 7.43 years in the conservative group and 56.1 ± 5.66 years in the surgical group. The medial malleolus was the most common ulcer site (82%). Mean ulcer size reduction was significantly greater in the surgical group (p < 0.0001). After two months, ulcer size decreased to 12.73 ± 2.85 mm in the surgical group and 27.73 ± 4.72 mm in the conservative group. Complete ulcer healing at six months was achieved in 90% of surgical patients and 63.3% of conservative patients (p = 0.0146). Conclusion: Surgical management provides faster and more complete healing compared to conservative methods. While conservative therapy is effective for symptom control, surgical correction of venous incompetence significantly improves healing outcomes and reduces recurrence, making it the preferred treatment modality},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kishore_2025,

title = {Revalidating preoperative prediction score and to develop a more accurate prediction score-to predict difficult cholecystectomy},

author = {T. Naga Raja Ravi Kishore and Ishrath Anjum and Zaid Mazhar Syed and Satya Srividya Kalluri and Syed Asif Shah Harooni},

url = {https://jccpractice.com/article/revalidating-preoperative-prediction-score-and-to-develop-a-more-accurate-prediction-score-to-predict-difficult-cholecystectomy-1502/},

doi = {10.61336/jccp/25-10-89},

issn = {2457-7200},

year  = {2025},

date = {2025-10-24},

urldate = {2025-10-24},

journal = {Journal of Contemporary Clinical Practice},

volume = {11},

issue = {10},

pages = {648-657},

abstract = {Background: Laparoscopic cholecystectomy is the gold standard for symptomatic gallstone disease due to its minimally invasive nature and faster recovery. However, intraoperative challenges can increase the risk of conversion and complications. Predicting surgical difficulty preoperatively enables better planning and patient safety. This study aimed to design and validate a scoring system to predict laparoscopic cholecystectomy difficulty using clinical and imaging parameters. Materials and Methods: A prospective study was conducted on 50 patients undergoing laparoscopic cholecystectomy at Princess Esra Hospital and Owaisi Hospital & Research Centre, Hyderabad, after obtaining ethical clearance. Clinical, biochemical, and imaging findings were analyzed, and scoring parameters were formulated to predict surgical difficulty. Results and Observations: Most patients were young adults (19–30 years) and female (76%), presenting predominantly with right hypochondrial pain and dyspeptic symptoms. Imaging revealed gallbladder wall thickening, CBD stones, and inflammatory changes in select cases. A scoring system comprising 21 preoperative and 13 intraoperative parameters was developed, stratifying patients into three risk categories: Very Low (0–6), Low to Moderate (7–14), and Moderate to High (15–30). Higher scores correlated with increased surgical difficulty and conversion rates. Conclusion: Laparoscopic cholecystectomy remains the safest and most effective treatment for gallbladder disease. The proposed scoring system provides a simple and reliable tool to predict operative difficulty, allowing for better surgical planning, appropriate allocation of resources, and improved patient outcomes},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kishore_2025b,

title = {A prospective study on independent risk factors for lower limb amputation in diabetic foot patients},

author = {T. Naga Raja Ravi Kishore and Satya Srividya Kalluri and Venugopal Sarveswaran},

url = {https://healthcare-bulletin.co.uk/article/a-prospective-study-on-independent-risk-factors-for-lower-limb-amputation-in-diabetic-foot-patients-4388/},

doi = {10.61336/ejcm/25-10-71},

issn = {2042-4884},

year  = {2025},

date = {2025-10-22},

urldate = {2025-10-22},

journal = {European Journal of Cardiovascular Medicine},

volume = {15},

issue = {10},

pages = {405-411},

abstract = {Background: Diabetic foot remains one of the most serious complications of diabetes mellitus, often leading to infection, ulceration, gangrene, and limb amputation. It reflects a complex interaction between neuropathy, ischemia, and infection. Early identification of risk factors is essential for prevention and limb preservation. Aim of the study was to identify and quantify the independent risk factors associated with lower limb amputation among patients with diabetic foot disease. Materials and Methods: This prospective descriptive analytic study was conducted at the Department of General Surgery, Sri Ramakrishna Hospital, Coimbatore, from November 2014 to November 2016. A total of 150 diabetic foot patients aged 18–80 years were included. Clinical evaluation, laboratory investigations, Doppler ultrasonography, and culture studies were performed. Variables such as age, sex, duration of diabetes, HbA1C level, peripheral vascular disease (PVD), neuropathy, smoking, foot deformities, and comorbid illnesses were analyzed. Statistical analysis was done using SPSS version 17.0, with p < 0.05 considered significant. Results: Among the 150 patients, 98 (65.3%) were males and 52 (34.7%) females, with the majority in the 51–60-year age group. Neuropathy was observed in 40%, and ischemia in 35.3% of patients. Overall, 74 patients (49.3%) required amputation—24 (16%) major and 50 (33.3%) minor—while 76 (50.7%) were managed conservatively. Foot infections were present in 68.6%, with Pseudomonas (15.3%) and Staphylococcus aureus (12.7%) being the most common pathogens. Univariate analysis revealed smoking, PVD, neuropathy, higher PEDIS grade (>3), and associated comorbidities as significant predictors of amputation (p < 0.05), whereas duration of diabetes, HbA1C level, previous amputation, and foot deformities were not statistically significant. Conclusion: Neuropathy, ischemia, and infection remain the principal determinants of amputation in diabetic foot disease. Smoking and systemic comorbidities further increase the risk. Early detection, strict glycemic control, proper foot care, and a multidisciplinary approach are essential to prevent limb loss and improve outcomes in diabetic patients.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Atharuddin_2025,

title = {A comparative study of wound healing and complications with the use of 1-0 vicryl vs 1-0 prolene for rectus closure},

author = {Athar Mohammed Atharuddin and Neda Faraz and Arshiya Fatima},

url = {https://jccpractice.com/article/a-comparative-study-of-wound-healing-and-complications-with-the-use-of-1-0-vicryl-vs-1-0-prolene-for-rectus-closure-1458/},

doi = {10.61336/jccp/25-10-55},

issn = {2457-7200},

year  = {2025},

date = {2025-10-15},

urldate = {2025-10-15},

journal = {Journal of Contemporary Clinical Practice},

volume = {11},

issue = {10},

pages = {372-380},

abstract = {Background: Surgery and sutures are inseparable. Down the ages, newer and more efficacious suture materials and techniques have been introduced. Among all wound closures, abdominal wound closure is the most challenging task for a surgeon. There are different techniques according to suture material, suturing technique and length of suture material that have been suggested optimal for rectus closure. These prospects are still under study and are controversial. This study was to compare the efficacy of vicryl and prolene for rectus closure by studying the wound healing and complication rates (wound infection, wound dehiscence, burst abdomen etc). Materials and Methods: The present prospective comparative study was conducted on patients admitted for surgeries in the Department of General surgery, Deccan College Of Medical Sciences, Hyderabad. for a period of 18 months. Prior to the initiation of the study, Ethical and Research Committee clearance was obtained from Institutional Ethical Committee. During present study total 50 patients meeting inclusion criteria were enrolled into the study. Results and observations: There was no statistical difference between the groups in terms of age (p: 0.1358); gender (p: 1.131); diabetic status (p: 1.1532); BMI (p: 1.1611); type of surgery (p: 0.8321); duration of surgery (p: 0.8321); intra operative hypotension prevalence (p: 0.1352); type of incisions (p: 1.3521); type of surgical site infections (p: 0.06). The incidence of burst abdomen (p: 0.01) was high in group B, day of burst abdomen incidence (p: 0.02), incidence of surgical site infections high in group B (p: 0.01); rate of wound healing was slow in group B (p: 0.001) Conclusion: From the present study we conclude that non-absorbable suture (prolene) was better in terms of wound healing and cosmesis as compared to absorbable suture used (vicryl) taking into consideration the points: wound dehiscence, burst abdomen incidence, surgical site infections incidence was higher in group B comparatively. Group B subjects had a slower rate of wound healing comparatively.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Faraz_2025,

title = {Role of c-reactive protein, serum amylase and apache II scoring system in predicting the severity of acute pancreatitis},

author = {Neda Faraz and Mohammed Abdul Hadi and Ameer Khan},

url = {https://jccpractice.com/article/role-of-c-reactive-protein-serum-amylase-and-apache-ii-scoring-system-in-predicting-the-severity-of-acute-pancreatitis-1219/},

doi = {10.61336/jccp/25-08-102 },

issn = {2457-7200},

year  = {2025},

date = {2025-08-25},

urldate = {2025-08-25},

journal = {Journal of Contemporary Clinical Practice},

volume = {11},

issue = {8},

pages = {761-766},

abstract = {Background: Acute pancreatitis is a catastrophic condition with many complications and poses a great challenge to the treating surgeon. 1020% of the patients who develop complications will not recover with simple supportive therapy. Hence, an accurate prediction of severity and prognostic monitoring are necessary to anticipate the early and late complications so as to consider aggressive treatment. The present study aimed at predicting the prognosis in patients with acute pancreatitis by using the serum AMYLASE, serum LIPASE, APACHE II scoring system and at determining the utility of these scores in further management. Methods and Material: 84 patients, who were admitted to the PES Institute of Medical sciences with the clinical and radiological evidence of acute pancreatitis with an elevation in the serum amylase levels, were the subjects of this study. Results: Among 84 patients, 50 had severe disease and 34 had mild disease based on serum CRP (P<0.05).On the first day of hospitalisation Serum amylase and APACHE II scoring system were analysed. Serum CRP taken at 48 hours of admission. The age of incidence is often between 31 to 40 years. Males are more commonly affected than females. Alcohol was the main factor in both mild and severe disease-related deaths. The upper limit in this study for serum amylase were 1000U/L, APACHE II score >8 and serum CRP >150mg/L. The percentile of patients for mild and severe pancreatitis for serum amylase, APACHE II score and serum CRP includes 83.3%, 45.2%, 40.5% and 16.7%, 54.8%, 59.5%. The standard deviation of serum amylase, APACHE II score and serum CRP includes 347.1,3.0, 24.1.The statistical inference of all the three parameters comparing one value with other parameters shows serum CRP has significant value of P<0.05. Conclusion: Serum CRP plays a significant role in stratifying individuals for early, aggressive treatment in order to reduce morbidity and mortality from acute pancreatitis. To define characteristics that allow for the establishment of multifactorial scores or biomarkers to predict acute pancreatitis severity and track disease progression, large population-based multi centre studies must be designed and conducted.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Goud_2025,

title = {Single-staged repair for penoscrotal hypospadias with tunica vaginalis flap},

author = {P. Umesh Chandran Goud and Loya Bharadwaj and Shireen Adeeb Mujtaba Ali and Mohammad Ikramuddin and Mohammed Khaja Arifuddin},

url = {https://journals.lww.com/sbvj/fulltext/2025/04000/single_staged_repair_for_penoscrotal_hypospadias.9.aspx},

doi = {10.4103/sbvj.sbvj_15_25},

issn = {2581-6039},

year  = {2025},

date = {2025-04-30},

urldate = {2025-04-01},

journal = {SBV Journal of Basic, Clinical and Applied Health Science},

volume = {8},

issue = {2},

pages = {75–77},

publisher = {Ovid Technologies (Wolters Kluwer Health)},

abstract = {Surgery at an early age is recommended for one of the most prevalent congenital genital defects, hypospadias. It is gradually evolving, frequently by repurposing decades-old therapeutic approaches. Preputial onlay flaps were most frequently utilized in the 1980s, although there is currently a resurgence of interest in the tunica vaginalis flap. In a selected number of patients with severe anomalies, hypospadias is surgically repaired in one stage. The process includes creating a neourethra and correcting the curvature of the penile shaft. For optimal functional and cosmetic outcomes, this neourethra requires an intermediate layer to be covered. The tunica vaginalis flap is one of the better choices for usage as an intermediate layer among the several local flaps.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2025c,

title = {Mesentric cyst with a twist},

author = { Juveria Fatima and Shaila Tasneem and Farha Naaz and Naushaba Tazeen and Idrees Akhtar Afroze and Syed Asif Shah Harooni},

url = {https://jmas.in/fulltext/154-1722832055.pdf?1755672275},

doi = {10.5455/jmas.214286},

issn = {2231-1696},

year  = {2025},

date = {2025-01-31},

urldate = {2025-01-31},

journal = {Journal of Medical and Allied Sciences},

volume = {15},

issue = {1},

pages = {88-91},

publisher = {Deccan College of Medical Sciences},

abstract = {With an incidence rate of 0.1-0.3% gastrointestinal stromal tumors (GIST) are rare to be found in extraintestinal locations known as extraintestinal GIST (EGIST). Mesenchymal in origin, they arise from interstitial cells of Cajal, a part of gastrointestinal autonomic nervous system (ANS). It is more common in males than females. GIST is mainly seen in stomach followed by small bowel, colon, rectum and esophagus. Incidence of EGIST is less than 1%. Patients with neurofibromatosis-1 has increased incidence of GIST. It can also present as Carney-Stratakis syndrome. GIST less than 2 cm is usually asymptomatic while GIST more than 2 cm presents with unexplained growth of abdomen, nausea, anemia, difficulty in swallowing, loss of appetite and weight loss. Herein we present a case of 31-yr old female, who presented with complaints of intermittent abdominal pain and was evaluated for infertility. Abdominal ultrasonography (USG) revealed cystic mass of mesentery. Computed tomography (CT) scan abdomen confirmed a cystic lesion with central necrosis arising from jejunal loops. Surgical excision of mesenteric cyst was performed and histopathological diagnosis of gastrointestinal tumor was given. Thus, high index of suspicion is required on part of pathologist to expect an EGIST mimicking as a mesenteric cyst.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Farzeen_2025,

title = {Exploring a rare entity: Myxoid liposarcoma on anterior abdominal wall},

author = { Mehrina Farzeen and Sumaiya Shireen and Naushaba Tazeen and Idrees Akhtar Afroze and Syed Asif Shah Harooni},

url = {https://jmas.in/?mno=215424},

doi = {10.5455/jmas.215424},

issn = {2231-1696},

year  = {2025},

date = {2025-01-31},

urldate = {2025-01-01},

journal = {Journal of Medical and Allied Sciences},

volume = {15},

issue = {1},

pages = {95-98},

publisher = {Deccan College of Medical Sciences},

abstract = {Myxoid liposarcoma is a soft tissue tumor. Out of all the malignant tumors, soft tissue tumors account for less than 1%, in which liposarcoma is the most common type of soft tissue tumor. The common site for liposarcoma is extremities and retroperitonium and on abdominal wall is exceptionally rare with only 22 cases reported so far. We report a case of 56 year old male patient presenting with anterior abdominal wall mass in left hypochondriac region of 6 months duration. There was no pain or discharge associated with it. On clinical examination, the mass was located on left upper quadrant of abdomen. Abdominal ultrasonography revealed well defined, hypoechoic, space occupying lesion. FNAC revealed scant fibroblast tissue. Trucut biopsy was advised. Radiological, clinical and cytological investigations were non- specific. An excision biopsy was performed and the sample was sent for histopathological examination. Gross examination revealed well circumscribed nodular myxoid mass, which was grey white in color. Microscopic examination revealed mesenchymal cells with myxoid rich stroma and cells show signet ring configuration. Pathological evaluation of surgical specimen is the gold standard for diagnosis. Complete excision with clear margin is the mainstay of treatment in view of its local recurrence. We report this case as myxoid liposarcomas are rarely seen in the clinic, here it has presented on an extremely unusual site, anterior abdominal wall.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bushra_2024,

title = {Molecular basis of sepsis: A new insight into the role of mitochondrial DNA as a damage-associated molecular pattern},

author = {Bushra and Shaik Iqbal Ahmed and Safia Begum and Maaria and Mohammed Safwaan Habeeb and Tahmeen Jameel and Aleem Ahmed Khan},

url = {https://www.sciencedirect.com/science/article/abs/pii/S1567724924001259?via%3Dihub},

doi = {10.1016/j.mito.2024.101967},

issn = {1567-7249},

year  = {2024},

date = {2024-11-01},

urldate = {2024-11-01},

journal = {Mitochondrion},

volume = {79},

issue = {suppl},

pages = {101967},

publisher = {Elsevier BV},

abstract = {Sepsis remains a critical challenge in the field of medicine, claiming countless lives each year. Despite significant advances in medical science, the molecular mechanisms underlying sepsis pathogenesis remain elusive. Understanding molecular sequelae is gaining deeper insights into the roles played by various damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) in disease pathogenesis. Among the known DAMPs, circulating cell-free mitochondrial DNA (mtDNA) garners increasing attention as a key player in the immune response during sepsis and other diseases. Mounting evidence highlights numerous connections between circulating cell-free mtDNA and inflammation, a pivotal state of sepsis, characterized by heightened inflammatory activity. In this review, we aim to provide an overview of the molecular basis of sepsis, particularly emphasizing the role of circulating cell-free mtDNA as a DAMP. We discuss the mechanisms of mtDNA release, its interaction with pattern recognition receptors (PRRs), and the subsequent immunological responses that contribute to sepsis progression. Furthermore, we discuss the forms of cell-free mtDNA; detection techniques of circulating cell-free mtDNA in various biological fluids; and the diagnostic, prognostic, and therapeutic implications offering insights into the potential for innovative interventions in sepsis management.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Murthy_2024,

title = {To study down staging locally advanced breast carcinoma: the role of neoadjuvant chemotherapy},

author = {T. S. R. Murthy and Mohammed Arshad Ali Khan and M. R. Madhu Mohan Reddy},

url = {https://jcdronline.org/index.php/JCDR/article/view/13551/7466},

doi = {10.48047/jcdr.2024.15.01.217},

issn = {0975-3583},

year  = {2024},

date = {2024-01-31},

urldate = {2024-01-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {15},

issue = {1},

pages = {1944-1951},

abstract = {Introduction: Although rare, locally progressed breast cancer is a major obstacle for clinicians. This study was conducted because there is a direct correlation between the pathological response to neoadjuvant chemotherapy and disease free survival. This study was out to evaluate the histological impact of neoadjuvant chemotherapy on breast cancer patients with locally advanced disease. Material and Methods: This study was observational based study. The research was carried out at the Department of General Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India. The study was done from September 2022 to July 2023. A total of twenty-five people were used as subjects in this research. Modified radical mastectomy was performed after clinical evaluation of tumour response and patient follow-up. Pathological reaction was assessed and notes were made on the specimen. Result: People in their 50s and 60s made up the bulk of the population. The majority of the 30 patients with locally advanced cancer (73%), ranging from stage IIIA to stage IIIB, were men.Nearly half of the patients tested positive for oestrogen receptors but negative for HER2, and a quarter of those individuals tested positive for all three.Everyone who tested positive for HER 2 was also considered to be a triple negative. Both the ER and PR positive tumour percentages were 67%.Forty percent of tumours tested positive for HER2. Possible explanations for the low response rate and high rate of ER positive include the fact that 83% of patients did not react to NACT and only 17% demonstrated a pathological response. Conclusion: Better prognosis may be possible if we could determine which tumours would respond best to which treatments. Recent developments in cancer biology and genetic profiling have the potential to revolutionise the clinical management of LABC by allowing for a more targeted and personalised approach.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Reddy_2024,

title = {Evaluation of the pathological response to neoadjuvant chemotherapy in locally advanced breast cancer},

author = {M. R. Madhu Mohan Reddy and Yasaswi Ponnapalli and Md. Samiuddin},

url = {https://jcdronline.org/index.php/JCDR/article/view/13553/7467},

doi = {10.48047/jcdr.2024.15.01.218},

issn = {0975-3583},

year  = {2024},

date = {2024-01-31},

urldate = {2024-01-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {15},

issue = {1},

pages = {1952-1958},

abstract = {Background and objective: To assess how patients with locally advanced breast cancer respond pathologically to neoadjuvant therapy. It is uncommon to have locally advanced breast cancer (LABC), and it poses significant clinical challenges. The purpose of the study was to look into the relationship between disease-free survival and the pathological response to neoadjuvant chemotherapy. Method: An observational study was conducted at Department of General Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India from December 2022 to November 2023. on a sample of 40 persons to assess the pathological response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. The study received ethical approval from the committee. Result: Between the ages of 50 and 60, 33% of the population fell. About half of the patients exhibited negative human epidermal growth factor receptor 2 (HER2), positive progesterone receptor (PR), and positive oestrogen receptor (ER). Sixty-seven percent of tumours tested positive for both the progesterone receptor (PR) and the oestrogen receptor (ER). Forty percent of the tumours had HER2 positive results. Merely 17% of the patient cohort exhibited a pathological reaction to neoadjuvant chemotherapy (NACT). 83% of the total did not respond.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Samiuddin_2024,

title = {An investigation of the antibiotic sensitivity of peritoneal fluid cultures in cases of perforative peritonitis},

author = {Md. Samiuddin and M. R. Madhu Mohan Reddy and Mallika Anjum},

url = {https://www.jcdronline.org/admin/Uploads/Files/65b63b946af163.82910711.pdf},

doi = {10.48047/jcdr.2024.15.01.222},

issn = {0975-3583},

year  = {2024},

date = {2024-01-31},

urldate = {2024-01-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {15},

issue = {1},

pages = {1982-1989},

abstract = {Introduction: Peritonitis is a prevalent issue encountered by General surgeons. Significant advancements in the treatment of peritonitis have occurred in recent decades, primarily through the utilisation of antibiotics and surgical interventions. The objectives of the study were to ascertain the antibiotic sensitivity and resistance pattern for routinely utilised antibiotics against the cultured microbes. Material and Methods: This study was conducted using a cross-sectional design. The research was carried out at the Department of General Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India. The study was done from October 2022 to September 2023. This study utilised a sample of 40 persons as subjects. Result: A common complication of perforation of the hollow viscus is secondary peritonitis. Because patients sometimes do not arrive at the hospital until much later, the fatality rate is significant. The age groups of 31–40 years old and 20–30 years old accounted for the bulk of the perforation cases in our study. The average age at which symptoms first appear is 35.26 years. Based on our findings, the second half of the duodenum accounts for 52% of perforations, whereas the stomach accounts for 42%. Among the organisms developed, Klebsiella accounted for 46% of the cases, E. coli for 34%, and just 2% displayed a combination of the two. Our study focused on analysing the sensitivity patterns of organisms that were cultivated. Ceftriaxone, ciprofloxacin, and amikacin were the most commonly found organisms that demonstrated sensitivity. Conclusion: The study found that the most common site of perforation is the duodenum, followed by the stomach. Peptic ulcer illness was the most common cause. The most common bacteria responsible for secondary peritonitis in these patients were Klebsiella and Escherichia coli, with mixed, proteus, and pseudomonas infections occurring very rarely. Cephalosporins, quinolones, and macrolides were the most effective antibiotics against Klebsiella and Escherichia coli, in that order of sensitivity.},

note = {Article not available},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2023d,

title = {Assessment of soluble thrombomodulin and soluble endoglin as endothelial dysfunction biomarkers in seriously ill surgical septic patients: correlation with organ dysfunction and disease severity},

author = {Mohammed Affan Osman Khan and Tarun Kumar Suvvari and Syed Asif Shah Harooni and Aleem Ahmed Khan and Syyeda Anees and Bushra},

url = {https://link.springer.com/article/10.1007/s00068-023-02369-8},

doi = {10.1007/s00068-023-02369-8},

issn = {1863-9933},

year  = {2023},

date = {2023-09-23},

urldate = {2023-09-01},

journal = {European Journal of Trauma and Emergency Surgery},

publisher = {Springer Science and Business Media LLC},

abstract = {Background: Sepsis, a complex condition characterized by dysregulated immune response and organ dysfunction, is a leading cause of mortality in ICU patients. Current diagnostic and prognostic approaches primarily rely on non-specific biomarkers and illness severity scores, despite early endothelial activation being a key feature of sepsis. This study aimed to evaluate the levels of soluble thrombomodulin and soluble endoglin in seriously ill surgical septic patients and explore their association with organ dysfunction and disease severity.

Methodology: A case control study was conducted from March 2022 to November 2022, involving seriously ill septic surgical patients. Baseline clinical and laboratory data were collected within 24 h of admission to the Surgical Intensive Care Unit. This included information such as age, sex, hemodynamic parameters, blood chemistry, SOFA score, qSOFA score, and APACHE-II score. A proforma was filled out to record these details. The outcome of each patient was noted at the time of discharge.

Results: The study found significantly elevated levels of soluble thrombomodulin and soluble endoglin in seriously ill surgical septic patients. The RTqPCR analysis revealed a positive correlation between soluble thrombomodulin and soluble endoglin levels with the qSOFA score, as well as, there was a positive association between RTqPCR soluble thrombomodulin and the SOFA score. These findings indicate a correlation between these biomarkers and organ dysfunction and disease severity.

Conclusion: The study concludes that elevated levels of soluble thrombomodulin and soluble endoglin can serve as endothelial biomarkers for early diagnosis and prognostication in seriously ill surgical septic patients.},

key = {pmid37741913},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2023b,

title = {Rare presentation of vagal paraganglioma in an early age: a case report and literature review},

author = {Asma Fatima and G. Raghavendra Prasad and Shaik Zahid Ali and Syed Faqeer Hussain Bokhari and Syed Abul Qasim Hussain Abedi and Ricardo Souza Júnior},

url = {https://pdf.sciencedirectassets.com/280165/1-s2.0-S2210261223X00066/1-s2.0-S2210261223004911/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEC8aCXVzLWVhc3QtMSJHMEUCIQDBGpUAAJD3f4cMWDSpTP9KNAmfiqJuoA2VkMv1kpifewIgaoAtoaMe7gNW2h2TLLww7V723OfVF44AfhsXxfcRqkkqsgUIKBAFGgwwNTkwMDM1NDY4NjUiDObQAAbK97IuiuD3miqPBYbr69qJ5oidw3icepSWPNNF4yqMwaOeUk6pf2JnKuCVM%2B2AqyaL1w63PMLM93qX7pK1lV%2BA8GPVlnP6vlSoXwkCDN4Nvpr2tqZbMn6BMAVLjYgROzQSheLwupsztBH1qeYvixkfMw%2BTSxE8o33pVxAHz6UTeT4RoO%2BBnSgDzO6jpdvemOm9HAn9Rmg2TtDvH3%2FqPvt6UkYy7z1VBCluhaoqeBjLoczsZ9f9Xr%2FrckqH5p1mL7pLaG%2FNNbIY16u9dAiBCXnv3jdZXwSyELCTdQlmcf%2BuzDija9wmpFvQ8Kd7iWPJ2PDV%2FelnKEfrbRKOkQI6jLZmPG5JjpYd%2FmvfMiU5LDGwAfvpIoUgbykG2V2cIEMXS%2FD1Dh0KmC2qEzrt6U8mEN6iwEsYlq%2B2qumXbRrzrenm4z0BOvZ4CVo%2FPpf8x3UNZ%2BESOJSlC6XlHwmv236oCY1oDW0DVMecwOYQ3QMgGW9sXZo6bBRoutMBF92kmzlFnvIW9RA%2FvzWx%2FrwQdYAJ8kA0jkjtVRkfF66cYv55vgZTcWFdrMOzHbjVjOgUbmcEyccgMQjGxSrTZi8hxqYbeTwvlNgnEneA86Os7l7S02s%2FiWWAtnNCk6Iwf37078%2Bs4tVTl1p7CCDYfsNARgJGszsnaMCJjUc9Xjt5puBA5qvRhY8HIwUlaEiQ2giSG9Pu3gzLxv9JYqAo9HdtU5Z8yw4Eq5gezpfAJ5i47fpI0zpsX1Fhm8xPpAeDdLpzNQJFa%2FtqBYmNxGMhizrCjKAoLfkP6w0JLzOfgGf8bNEihnioVgtxZdE3vVjXtHpamngRAvhnR%2F1l5vTyulq2sr0%2B4bc1zEdfwa5gVwyQMTXEcYb3hnPBaguTpmydgxgwwJm6qAY6sQEZFVpUp4ow8UY9TWysO9tIPa2h7AgOp%2BGRJMK%2BQ83L8lEHhpGGyeap8ydxQTxgjSG1%2BeN9VDRf8HAtR0OzV%2BR2MwTLz5V2Wn3xaM4i4dUxCrerMOC9P2fuGcO5exrX5Wujsv%2B8%2Bk0%2BKeJKJhIkl9%2Bus9OIwz4XAMilWgHDdY%2Ba2yA2p4qRv0h%2FHAxmMIm57vDRXDBpe30aRTccT8Fd%2B0%2BJmbpsK%2F1umKB7hDiUH4lr0DU%3D&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20230923T073437Z&X-Amz-SignedHeaders=host&X-Amz-Expires=300&X-Amz-Credential=ASIAQ3PHCVTYQNTLULHS%2F20230923%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Signature=5cf2ce751a3f530d41d876d5adc18b4524aedeb75bf0ccb2c500677a57832012&hash=4f124584f3bb971c35e6edd96d2a338341f63587e5dd785f792c5ea486738432&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S2210261223004911&tid=spdf-97b6fb85-7d4b-4620-a09e-da76325953a4&sid=d3a802bb9c9bc24c5d8ab168346de759acb2gxrqb&type=client&tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&ua=0f0d5750015654015753&rr=80b11b32889d2e87&cc=in},

doi = {10.1016/j.ijscr.2023.108362},

issn = {2210-2612},

year  = {2023},

date = {2023-05-27},

urldate = {2023-05-27},

journal = {International Journal of Surgery Case Reports},

volume = {107},

pages = {108362},

publisher = {Elsevier BV},

abstract = {Introduction and importance: Vagal paragangliomas of neck are rare tumours of neural crest origin usually arising in elderly age with female predominance. They have a vague clinical presentation therefore difficult to diagnose preoperatively. We hope that this case report and literature review would add to the existing literature and help devise a comprehensive diagnostic and therapeutic plan for vagal paragangliomas. Case presentation: We report a case of vagal paraganglioma occurring in a 13-year-old male which is an extremely rare presentation in this age group. The patient presented with a large solitary painless progressively growing mass in posterior triangle of neck. External jugular vein was stretched and trachea was deviated medially. The mass was arising via a twig from vagus nerve and was surgically excised. Diagnosis was established post-operatively through histopathological analysis. Clinical discussion: Vagal paraganglioma is a rare occurrence in male teenagers and may mimic schwannoma, neuroma, jugular meningioma, or other gangliomas. Surgical excision is mainstay of treatment but resultant vagal complications and neurological consequences are usually unavoidable. Nonetheless, the prognosis may be easily improved with sound surgical judgement, skill, and routine follow-up. Conclusions: Vagal paraganglioma usually presents as a swelling in neck and cannot be diagnosed on simple clinical examination. CT scan and MRI are imaging modalities of choice and can be coupled with angiography to increase diagnostic accuracy. Although both radiation therapy and surgical excision have both been found to be successful treatment options, it is still unclear which is more beneficial.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hadi_2023,

title = {A study on perforations, operative modalities, complications and its outcome post operatively},

author = {Mohammed Abdul Hadi and Atif Abdul Samee and J. Kondal Reddy},

url = {https://www.academicmed.org/Uploads/Volume5Issue1/40.-53.-JAMP_Taqui-190-195.pdf},

doi = {10.47009/jamp.2023.5.1.40},

issn = {2687-5365},

year  = {2023},

date = {2023-01-31},

journal = {International Journal of Academic Medicine and Pharmacy},

volume = {5},

issue = {1},

pages = {190-195},

abstract = {Background: To assess to common type of perforations and their presentation, operative modalities, complications arising postoperatively at our hospital. Materials and Methods: It was an observational study; this study is based on analysis of 65 cases of benign cause of gastrointestinal perforation. Result: The time laps between onset of pain and presentation at the hospital was greater in the > 24 hours group with 58.5% of the patients presenting after 24 hours. Peptic ulcer perforation (32.31%) is the major cause of gastrointestinal perforation followed by appendicular (26.4%) tubercular (15.4%) and typhoid (10.8%).80% of cases had guarding /rigidity with 47.7% Patients presented with distention of abdomen. 71% of cases had gas under the diaphragm with majority of them in peptic ulcer perforation and least appendicular perforation. Simple closure with Omental patch was the operative procedure done for all cases of peptic ulcer perforation and appendectomy for appendicular perforation. Half of patients with typhoid perforation closure in two layers and remaining half were treated with resection and end to end anastomosis. Most common Complication recorded in this study was SSI (16.9%) which was similar to that of respiratory infection/distress. Mortality in our study was 3.1% and was due to septicemia with other age group, delayed presentation to hospital and other associated co-morbidities being the additives factors. Conclusion: Finally surgical treatment is the most definitive treatment for perforative paternities patients and postoperative care remain extremely important in the better outcome of the patients.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ahmed_2022b,

title = {Adult autoimmune enteropathy in India: a rare entity and unusual presentation},

author = {Sheraz Ahmed and Ganji Ravi},

url = {https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/fileview/adult-autoimmune-enteropathy-in-india--a-rare-entity-and-an-unusual-presentation_October_2022_3556810261_8112221.pdf},

doi = {10.36106/ijsr/8112221},

issn = {2277-8179},

year  = {2022},

date = {2022-10-01},

urldate = {2022-10-01},

journal = {International Journal of Scientific Research},

volume = {11},

issue = {10},

pages = {24-26},

publisher = {World Wide Journals},

abstract = {Introduction: Autoimmune enteropathy is an X-linked autoimmune disease. A syndrome of intractable diarrhea, varying levels of villous atrophy of small intestine , presence of circulating autoantibodies to enterocytes. Diagnostic criteria is any 3 of the following features 1) features of malabsorption 2) Diarrhea > 6 weeks 3) HPE showing villous blunting with crypt and intraepithelial lymphocytosis 4) exclusion of other causes of villous atrophy like celiac disease and refractory sprue 5) serology positive for antibodies like anti-enterocyte and anti-goblet. Aims & objectives:The aim of this case report was to report a rare case of autoimmune enteropathy in an Indian female , with an atypical presentation with diagnosticand treatment challenges. The typical presentation of autoimmune enteropathy is chronic diarrhea with features of malnutrition andDiscussion:weight loss. But the presentation in this patient was more in favour of presentation of koch's abdomen , mostly of TB peritonitis with ascitic component. . Adult autoimmune enteropathy being a rare entity is thought late in differential diagnosis. The presence of antibodies , intraoperative findings and response to steroids favour autoimmune enteropathy. Although AIE is a rare entity,a multifactorial and a high degree of suspicion is necessary for diagnosis. In a country like India, where tuberculosis is so prevalent, other differential diagnosis should also be thought. Conclusion:of before coming to a conclusion.,as other diseases like autoimmunity previously thought to be rare are not so. ATT should only be started after confirming the diagnosis with histopathology report.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Harooni_2022,

title = {Mortality prediction score for hirschsprung's disease-associated enterocolitis: a novel mortality prediction model},

author = {Syed Asif Shah Harooni and G. Raghavendra Prasad and Gayatri Reddy Danda and Mahera Naureen},

url = {https://journals.lww.com/jiap/fulltext/2022/27050/mortality_prediction_score_for_hirschsprung_s.16.aspx},

doi = {10.4103/jiaps.jiaps_243_21},

issn = {0971-9261},

year  = {2022},

date = {2022-09-09},

urldate = {2022-09-09},

journal = {Journal of Indian Association of Pediatric Surgeons},

volume = {27},

number = {pmid36530801},

issue = {5},

pages = {594-599},

abstract = {Introduction: Enterocolitis associated with Hirschsprung's disease is a fatal and serious complication. Number of scoring systems are in vogue to grade the severity of Hirschsprung's disease associated with enterocolitis (HDAEC), but none of these scoring systems help predict mortality. Hence, we attempt to develop a mortality prediction model (MPM) for HDAEC. Materials and Methods: A retrospective analysis of all cases of HDAEC encountered was analyzed. We also used the parameters of Elhalaby et al. for data collection. A total number of 71 cases were analyzed with regard to mortality in relation to each parameter. Sensitivity and specificity were calculated by statistician, and based on these values, a scoring model was proposed. All those with predicted mortality were given score 2 and those who did not were given score 1. Results: A total score of more than 16 predicted mortality, a score of <10 predicted survival, and a score between 11 and 15 predicted survival with morbidity. Conclusion: A MPM for HDAEC is being proposed.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Samee_2022,

title = {A study on clinical and microbial culture analysis in diabetic foot disease},

author = {Atif Abdul Samee and Mohammed Abdul Hadi and Syeda Hafsa Rumaan},

url = {http://jcdronline.org/index.php/JCDR/article/view/7238},

doi = {10.31838/jc9r.2022.13.08.236},

issn = {0975-3583},

year  = {2022},

date = {2022-08-31},

urldate = {2022-08-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {13},

issue = {8},

pages = {1891-1900},

abstract = {Background:To study the graphic includes of diabetic foot disease in relation with age, sex and blood glucose levels of diabetic patients at Owaisi Hospital & Research Centre. Material and Methods:The present study is descriptive and cross-sectional study of diabetic patients with the diabetic foot lesions (Ulcer, cellulitis or osteomyelitis) of the patients or in patients of Medicine, Surgery and Orthopaedic departments at Owaisi Hospital & Research Centre. The Sample study was done at the Department of Microbiology, here at Deccan College of Medical Sciences from 1st October 2021 to 30th September 2022. Results:A total of 76 microbes were isolated from 30 samples of pus and other executes. It

was seen that seen that there was high prevalence of infection males then in females. Almost all the cases studied showed high incidence of uncontrolled diabetes with blood glucose levels higher than 200 mg/dl. Age group affected was studied and it was found that the cases with age group of 65-75 years were highest affected (40%). Majority of samples collected were polymicrobial (nos .22-73.33%) and some also showed more than the microbes, the

others were monomicrobial (nos 6-20%) and only two (6.67%) of the samples showed no growth for microbes. Aerobic bacteria showed prevalence in the sample collected (nos 54-71.05%) anaerobic bacteria were 22(28.95%) in number. A total of 29 cocci and 47 bacilli were isolated. Gram –straining showed that there was prevalence of gram-positive bacteria (nos.39) then gram negative was 37 in number. Conclusion:Majority of diabetic foot ulcers were in farmers and people of other slums. These people of the slums showed diabetic foot ulcerations predominantly due to Trauma despite

the fact that on the other hand the people of privileged class showed DFU’s due to High incidence of uncontrolled diabetes with blood glucose levels higher than 200 mg/dl. Gram – straining showed that there was high prevalence of gram-positive bacteria than gram negative bacteria.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Husayni_2022,

title = {The use of urinary amylase levels in the diagnosis of acute pancreatitis},

author = {Syed Mohammed Sajjad Husayni and Mohammed Naqi Zain and Mohammed Shazad Ahmed},

url = {https://www.ejmcm.com/archives/volume-9/issue-3/4902},

issn = {2515-8260},

year  = {2022},

date = {2022-03-31},

urldate = {2022-03-31},

journal = {European Journal of Molecular & Clinical Medicine},

volume = {9},

issue = {3},

pages = {5029-5038},

abstract = {Background:Acute pancreatitis is a relatively common but potentially fatal disease seen in surgical practise. Clinical examination, laboratory investigations, and imaging techniques are used to make a diagnosis of the disease. Patients usually present with severe pain in the epigastric region that radiates to the back. Serum levels of amylase and lipase that are more than three times the normal value usually indicate acute pancreatic inflammation. When clinical and laboratory investigations fail to diagnose the disease despite a strong suspicion of acute pancreatitis, radiological investigations are used to make a diagnosis. Urinary clearance of pancreatic enzymes from the circulation increases in acute pancreatitis. This is a study that will use urinary amylase levels to diagnose acute pancreatitis in a non-invasive manner. Objectives: To diagnose acute pancreatitis using urine amylase levels in conjunction with other specific tests

such as serum lipase and abdominal ultrasound, and to demonstrate that urine amylase can be used to diagnose acute pancreatitis. Materials and Methods: It is a case control study with 40 patients diagnosed with acute pancreatitis and 40 patients admitted with other diagnoses. Patients admitted to Princess Esra Hospital between November 2019 and May 2021 were chosen as cases and controls. Serum amylase, serum lipase, and urinary amylase levels were measured in

both the case and control groups. After comparing serum amylase, serum lipase, and urinary amylase levels in cases and controls, the sensitivity and specificity of these enzymes were determined.The authors concluded that serum amylase had the highest sensitivity (100 percent) and serum lipase had the highest specificity (100 percent) after analysing serum amylase, serum lipase, and urinary amylase results in both cases and controls (95 percent). Urine amylase's sensitivity and specificity were found to be 98.33% and 95%, respectively. The area under the curve for serum amylase, serum lipase, and urinary amylase was found to be 0.987, 0.995, and 0.935, respectively, using ROC curve analysis.

Conclusion: Because serum amylase, serum lipase, and urinary amylase have comparable sensitivity and specificity, as well as comparable areas under the curve on ROC analysis for the diagnosis of acute pancreatitis, the authors conclude that urinary amylase can be used in the diagnosis of acute pancreatitis.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zain_2022,

title = {A study on post operative complications of thyroid surgery},

author = {Mohammed Naqi Zain and Mohammed Shazad Ahmed and Syed Mohammed Sajjad Husayni},

url = {https://ejmcm.com/issue-content/a-study-on-post-operative-complications-of-thyroid-surgery-4889},

issn = {2515-8260},

year  = {2022},

date = {2022-03-31},

journal = {European Journal of Molecular & Clinical Medicine},

volume = {9},

issue = {3},

pages = {5039-5047},

abstract = {Background:The postoperative consequences of thyroid surgery have long been recognised by goitre surgeons. These problems may be serious enough to endanger the patient's life or cause physical or physiological limitations. Given the severity of the consequences, they must be kept to a minimum in this age of contemporary surgery. Moreover, for surgery to remain a dominating treatment option for thyroid illness, its complications must be less than other effective treatments. Aim: objectives of this study is to investigate preoperative factors that influence complication rates, complication rates linked with thyroid surgery type, problem types, complication onset time, complication duration, complication management. Materials and Methods: The current study lasted 18 months from January 2019 to July

2020. Princess Esra Hospital, Deccan College of Medical Sciences, Hyderabad. The study included a prospective analysis of 80 goitre surgeries. These cases were clinically investigated and recorded using the attached proforma. Results: A study of 80 goitres having surgery(cases that underwent goiter surgery) revealed Thyroid problems affect women more than men. The hospital saw the most patients in their third decade. Multinodular Goitre in Euthyroid Status was the most common clinical diagnosis. The most prevalent histology diagnosis was Nodular Colloid Goitre. Subtotal thyroidectomy was the most common procedure for goitre. Complications after surgery included wound infection. This trial had no fatality and little morbidity. It is possible to do thyroid surgery with little morbidity and mortality

for a wide range of thyroid illnesses if done gently with thorough attention to hemostasis and structural features.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ahmed_2022,

title = {A clinical study of obstructive jaundice secondary to choledocholithiasis},

author = {Mohammed Shazad Ahmed and Syed Mohammed Sajjad Husayni and Mohammed Naqi Zain},

url = {https://ejmcm.com/issue-content/a-clinical-study-of-obstructive-jaundice-secondary-to-choledocholithiasis-4891},

issn = {2515-8260},

year  = {2022},

date = {2022-03-31},

journal = {European Journal of Molecular & Clinical Medicine},

volume = {9},

issue = {3},

pages = {5048-5054},

abstract = {Background:Humans have long known about jaundice. Obstructive jaundice is common in general surgery. Intrahepatic or extrahepatic blockage can cause obstructive jaundice. Most patients with suspected biliary blockage start with an

abdominal ultrasound. This study aims to determine the prevalence of obstructive jaundice owing to choledocholithiasis in my hospital, the role of ultrasound in detecting such cases, and the treatment options available at Princess Esra Hospital Hyderabad. Materials and Methods: Between June 2019 and June 2021, 24 patients with obstructive

jaundice due to choledocholithiasis were studied at Princess Esra Hospital in Hyderabad. These patients received surgery. The proforma was used to assess these patients both pre- and post-operatively. Results: Obstructive jaundice due to choledocholithiasis was 0.14 percent in hospitals. The patients were mostly female (16:4).Symptoms presented in decreasing order of frequency. 100% jaundice, 95% abdominal pain, 50% nausea/vomiting, 50% itching (35 percent), Fever with chills and rigours (25%) Steatorrhea (10%) and abdominal mass (5%).Ultrasound showed stones in 16 (80%) and dilated CBD in all 24 (100%) instances (100 percent ). 11 patients had choledocholithiasis. Four instances had

choledocholithiasis and cholelithiasis. The investigation found one incidence of choledocholithiasis with CBD stricture. The most common surgical technique was choledochoduodenostomy (50%) followed by choledochotomy with T-tube drainage (40%) One case each of choledocho-jejunostomy and transduodenal sphincter. All twenty instances had cholecystectomy. All cases were monitored for 1-6 months with no complaints. Conclusion:Patients with obstructive jaundice are more susceptible to infections due to impaired liver function. It's also critical to identify specific risk factors in biliary tract surgery patients. Our study shows that ultrasound is the cheapest, safest, and most reliable diagnostic technique for postoperative jaundice. Despite the advent of laparoscopic CBD exploration, open, internal, and external biliary drainage procedures are still used successfully in areas lacking technology and experience.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{AbdurRaheem_2022b,

title = {Defining wider indications for stoppa repair other than recurrent hernias},

author = {Juwairiah Abdur Raheem and Suresh Chandra Annu and Rabiya Begum and Hafsa Iqbal and Mohammed Abdul Majid Adil},

url = {assets.cureus.com/uploads/case_report/pdf/90014/20220430-11451-194ai6m.pdf},

doi = {10.7759/cureus.23671},

issn = {2168-8184},

year  = {2022},

date = {2022-03-31},

urldate = {2022-03-31},

journal = {Cureus},

volume = {14},

issue = {3},

pages = {e23671},

publisher = {Cureus, Inc.},

abstract = {Managing complex inguinal hernias has been a constant challenge for surgeons and its treatment is not without challenges with the routine current techniques. Complex inguinal hernias especially recurrent have been managed by the Rives-Stoppa technique which is an established suture-less, tension-free, and absolute method of treatment with minimal recurrence rates. Traditionally, this surgical technique is most indicated in recurrent inguinal hernias, but we aim to assess the usefulness of this procedure for the treatment of complex inguinal hernias in individuals presenting for the first time. We report four varied cases of complex inguinal hernias, repaired by the open Rives-Stoppa technique, and discuss its indications, technique of repair, and current status.},

key = {pmid35505699},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{AbdurRaheem_2022,

title = {Is abdominal cocoon a sequela in recovered cases of severe COVID-19?},

author = {Juwairiah Abdur Raheem and Suresh Chandra Annu and Lahari Ravula and Sara Samreen and Ariyan Khan},

url = {https://www.cureus.com/articles/86570-is-abdominal-cocoon-a-sequela-in-recovered-cases-of-severe-covid-19#!/},

doi = {10.7759/cureus.22384},

issn = {2168-8184},

year  = {2022},

date = {2022-02-19},

urldate = {2022-02-19},

journal = {Cureus},

volume = {14},

issue = {2},

pages = {e22384},

publisher = {Cureus, Inc.},

abstract = {Abdominal cocoon is one of the rare causes of intestinal obstruction mostly diagnosed at the operating table. Its etiology is primarily unknown but can be secondary to known causes. The involvement of the gastrointestinal (GI) system was a common feature during the second wave of COVID-19, and at present, there are reports of GI symptoms in patients who have completely recovered from COVID-19. Abdominal cocoon formation has been reported during the active stage of COVID-19 but not as its sequela. We report two cases with a high degree of suspicion of abdominal cocoon formation in middle-aged individuals with no comorbidities, who recovered from a severe form of COVID-19.},

key = {pmid35371817},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shakeeb_2021,

title = {Giant ovarian cyst in 18 year old female– a case report},

author = {Momin Shakeeb and Heena Khatoon and Alina Khan and Sumaiya Sehrish and Syed Murtuza Hashmi and Mohammed Nizamuddin and Wafa Yasmeen},

url = {https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/fileview/giant-ovarian-cyst-in-18-year-old-female--a-case-report_December_2021_3856870186_6100423.pdf},

doi = {10.36106/ijsr},

issn = {2277-8179},

year  = {2021},

date = {2021-12-01},

urldate = {2021-12-01},

journal = {International Journal of Scientific Research},

volume = {10},

issue = {12},

pages = {10-12},

abstract = {Ovarian cysts are common, and are usually less than 4cm. A giant cyst in one which is more than 10cm. Giant cystadenocarcinomas of the ovary are less frequently described. Most of the ovarian carcinomas are of serous type and only 3-4% are of mucinous type. Ovarian mucinous tumors consist of benign, borderline, and carcinomatous tumors. Giant cysts require resection because of compressive symptoms and/or risk of malignancy and their management invariably requires laparotomy to prevent perforation and spillage of the cyst uid into peritoneal cavity. Here, we present a case of an 18 year old female with rapidly progressing abdominal distension and vague abdominal pain. Along with clinical evaluation and lab investigations she was subjected to imaging which included Ultrasonography and MR Imaging. She underwent exploratory laparotomy for excision of the cystic mass. On histopathological examination, mass was found to be mucinous cystadenocarcinoma with low malignant potential. The main aim of this report is to draw attention to huge ovarian epithelial cysts with unsuspected presentation contributing to any underdiagnosis, misdiagnosis, and mismanagement that might occur.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Prasad_2021b,

title = {Congenital pyloric atresia: experience with a series of 11 cases and collective review},

author = {G. Raghavendra Prasad and J. V. Subba Rao and Firdous Fatima and Fariha Anjum},

url = {https://www.jiaps.com/temp/JIndianAssocPediatrSurg266416-2971273_081512.pdf},

doi = {10.4103/jiaps.JIAPS_295_20},

issn = {0971-9261},

year  = {2021},

date = {2021-11-12},

urldate = {2021-11-12},

journal = {Journal of Indian Association of Pediatric Surgeons },

volume = {26},

issue = {6},

pages = {416-420},

abstract = {Introduction: Pyloric atresia is a rare cause of congenital gastric outlet obstruction. It is often associated with epidermolysis bullosa (EB). Rarity and experience with 11 cases are the reason for this publication. Aims and Objectives: The aim and objective of this study is to present our experience of 11 cases of congenital pyloric atresia and correlate with available literature. Materials and Methods: This was retrospective cohort of 11 cases correlative comparative study. Data of all the 11 cases from 1982 to 2019 were collected, reviewed, and analyzed. The parameters studied included age, gender, antenatal diagnosis, postnatal diagnosis, preoperative management, intraoperative findings, postoperative course outcome, associated anomalies, and any genetic studies if done. All these parameters were compared with published data. Results: There were 11 cases in the present series with six boys and five girls. Most of them presented at varying periods from birth to day 1 of life. Eight cases of type 1 pyloric atresia, two cases of type 2 pyloric atresia, and one case of type 3 pyloric atresia constituted the cohort. Five out of 11 cases were associated with EB. Two out of six cases with isolated pyloric atresia and four out of five cases with EB died. Discussion: Congenital pyloric atresia may be isolated or associated with EB. Three varieties of pyloric atresia were described. Association with EB increases the mortality. Conclusions: Review and analysis of 11 cases of pyloric atresia compared with published literature is being reported. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Prasad_2021,

title = {Abdominal cocoon: a diagnostic puzzle, multiple causes similar presentation– experience with 38 cases in search of a reliable imaging sign},

author = {G. Raghavendra Prasad and J. V. Subba Rao and Mahera Naureen and Gayatri Reddy Danda},

url = {https://journals.lww.com/kesg/fulltext/2021/27010/abdominal_cocoon__a_diagnostic_puzzle,_multiple.4.aspx},

doi = {10.4103/ksj.ksj_5_21},

issn = {0973-3051},

year  = {2021},

date = {2021-06-30},

urldate = {2021-06-30},

journal = {Kerala Surgical Journal},

volume = {27},

issue = {1},

pages = {8-12},

abstract = {Introduction: There are varied causes for abdominal cocoon. This study aims to present the varied causes of abdominal cocoon and definite pre operative indicator if any. Materials and Methods: A retrospective analysis of 38 cases of abdominal cocoon formed the cohort. An attempt was made to compare with the published cases of abdominal cocoon. Results: Giant cystic meconium peritonitis and para duodenal hernias were the most common non tubercular acute abdomen in children. Tubercular cocoon, cerebrospinal fluid CSF pseudocyst, ruptured ovarian cyst and idiopathic nonspecific sclerosing peritonitis were other causes. Imaging analysis showed clustering of bowel loops and well defined sac were the most reliable predictors. A comprehensive review of 38 cases of abdominal cocoon showed clustering of the bowel loops as the most reliable preoperative indicator of abdominal cocoon. Conclusions: Though there are varied causes for abdominal cocoon, clustering of bowel loops and well defined sac were the most reliable predictors.

},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fareedullah_2021,

title = {Evaluation of antibiotic usage in skin and soft-tissue infections and its antimicrobial susceptibility testing: a hospital-based cross-sectional study},

author = {Mohammed Fareedullah and Zareen Unnisa and Shajiya Khan and Fakeha Fatima and Afifa Khan and Syed Nusrath Farees and Mohammed Khaleel},

url = {https://www.jhrr.org/temp/JHealthResRev8127-1805027_050050.pdf},

doi = {10.4103/jhrr.jhrr_34_20},

isbn = {2394-2010},

year  = {2021},

date = {2021-05-29},

urldate = {2021-05-29},

journal = {Journal of Health Research and Reviews},

volume = {8},

issue = {1},

pages = {27-33},

abstract = {Aim: To evaluate the antibiotic usage in skin and soft-tissue infections (SSTIs) and to study the sensitivity pattern of identified microorganisms from antimicrobial susceptibility testing (AST) data. Materials and Methods: This was a cross-sectional study carried out in the Inpatient Department of General Surgery at Owaisi Hospital & Research Center, Hyderabad, for 6 months to collect 50 swab samples aseptically from the subjects with diverse SSTIs at the day of admission before the administration of antibiotics, and AST was done using Kirby Bauer disc diffusion method based on the guidelines of Clinical Laboratory Standard Institute (CLSI). Results: Of the 50 swab samples, 43 were culture positive and 7 were culture negative, and the highest number of cases was of cellulitis (14.28%). The most commonly isolated pathogen was Staphylococcus aureus (30.23%). On the basis of antibiotic sensitivity testing, we found that Ciprofloxacin was the most potent drug, followed by Ceftriaxone and Amikacin, for overall bacterial isolates. In our study, the treatment adhered to IDSA guidelines in 50% of cases and we found that many antibiotics were resistant. In cases of gangrene and abscess, a striking deviation from the guidelines (60% and 77.7%, respectively) was seen. Conclusion: This study guided us toward an appropriate treatment plan for the management of some SSTIs. The disproportionate and tedious use of antibiotics should be abstained as this may drive the evolution of resistant microorganisms that are even more difficult to get rid of.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ravi_2021,

title = {Extrapulmonary tuberculosis: are we barking up the wrong tree? A 4-yr naturalistic follow up study},

author = {Ganji Ravi and Bushra Khan and Mohammed Jalaluddin and Haneefa Khan and Swaroopa Ganji},

url = {https://www.ijsurgery.com/index.php/isj/article/view/6804/4368},

doi = {10.18203/2349-2902.isj20205889 },

issn = {2349-2902},

year  = {2020},

date = {2020-12-28},

urldate = {2020-12-28},

journal = {International Surgery Journal},

volume = {8},

issue = {1},

pages = {253-260},

abstract = {Background: Aim of the study was to determine if extra-pulmonary tuberculosis (EPTB) is a communicable disease as commonly perceived or a disease of host immune dysfunction. Methods: Patients with clinical suspicion of EPTB, in general surgery and orthopaedic department of twin hospitals of Deccan College of Medical Sciences, between the period of January 2015 and December 2017, were investigated appropriately and those found to have confirmed TB were enrolled in the study and followed up for 1 year. Simultaneously patient’s details registered under RNTCP in the two local community health centres were collected and compared with the hospital based study. Results: Of 319 patients with clinical features, 267 were confirmed with EPTB- maximum number with lymph nodal disease (127) followed by extremity bone and joint (63), spine (38), skin and soft tissues (25) and abdominal tb (19). Method of confirmation differed for each site. Detection by AFB being the least sensitive followed by AFB culture. The best method of diagnosis being histopathological examination. Conclusions: Immunity plays a major role in site of reactivation of TB and healing of disease irrespective of duration of anti-tuberculous chemotherapy or surgical intervention.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hadi_2020,

title = {A study on different modalities of treatment for pilonidal sinus},

author = {Mohammed Abdul Hadi and Syed Mujtaba Ibrahim and Atif Abdul Samee},

url = {https://www.surgeryscience.com/articles/544/4-4-16-339.pdf},

doi = {10.33545/surgery.2020.v4.i4b.544},

issn = {2616-3462},

year  = {2020},

date = {2020-09-21},

urldate = {2020-09-21},

journal = {International Journal of Surgery Science},

volume = {4},

issue = {4},

pages = {87-91},

abstract = {Background: Excision with lay open method and excision with primary closure (simple closure, z-plasty,

limberg flaps are both radical methods for treating pilonidal sinus. The ideal operation should be simple

and should not require a prolonged stay, have low recurrence, failure rate and post-operative complication.

Aim& Objective: The main objective of the present study to compared different techniques for treatment

of sacrococcygeal pilonidal sinus. Methodology: It was a cross sectional study. The materials for this study was taken from the patient admitted to Owaisi hospital from Jan 2013-Dec 2014 (2yr period) Twenty eight patients with pilonidal sinus who were admitted to Owaisi hospital. Results: In the present study, 15 out of 28 cases were treated by excision and lay open method. The mortality was nil, but the recurrence was 1 and 2 failures were noticed (totally 22.6% failure) in terms of morbidity. Patients abstained from work till the wound healed i.e. 44-68 days(average 49.5 days).The remaining 13 cases were operated by excision and primary closure (simple closure, z-plasty, limberg flap method) out of which 8 cases were treated with z-plasty and 2 cases with simple primary closure and 3 cases with limberg flap method. The mortality was nil, the recurrence rate and post-operative complications were nil and all patients returned to work early within 7 days. Conclusion: Finally we concluded that all cases where closure is possible should be treated with different closure techniques (simple closure, z-plasty, limberg flap). Deep gluteal cleft is flattened with z-plasty and limberg flap technique. Hence the suction effect is obliterated. All predisposing factors are countered by flap technique hence flap techniques are ideal for treatment for pilonidal sinus. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khajjayam_2020,

title = {Clinical study of common bile duct stones with reference to surgical management},

author = {Radha Krishna Khajjayam and Apoorva Vempati and Syed Mujtaba Ibrahim},

url = {https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/fileview/clinical-study-of-common-bile-duct-stones-with-reference-to-surgical-management_June_2020_1591091194_1608592.pdf},

doi = {10.36106/ijsr},

issn = {2277-8179},

year  = {2020},

date = {2020-06-30},

urldate = {2020-06-30},

journal = {International Journal of Scientific Research},

volume = {9},

issue = {6},

pages = {75-78},

abstract = {Background: Common bile duct stones (CBDS) occur in 8%-20% of patients suffering from gallstones. There is controversy regarding the management of CBDS due to availability of variety of therapeutic procedures each one having different advantages and limitations. Materials and methods: A prospective study was conducted from September 2013 to November 2015 in patients diagnosed to have choledocholithiasis. Results: Abdominal pain was the most common presenting symptom. Raised serum bilirubin and alkaline phosphatase was the most common biochemical abnormality. Out of 30 patients who underwent common bile duct (CBD) exploration 17 patients underwent T-tube drainage and 13 patients underwent choledochoduodenostomy (CDD).The CDD group had a signicantly lesser hospital stay when compared to T-tube group. Conclusion: In this era of endoscopy, surgery still has a role in the management of choledocholithiasis when ERCP fails. Surgical exploration achieves high success rates and is associated with acceptable morbidity. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ibrahim_2020,

title = {Evaluation of different methods of management in pseudocysts of pancreas},

author = {Syed Mujtaba Ibrahim and Atif Abdul Samee and Mohammed Abdul Hadi},

url = {https://www.casereportsofsurgery.com/article/12/2-1-4-971.pdf},

issn = {2708-1494},

year  = {2019},

date = {2019-12-07},

urldate = {2019-12-07},

journal = {International Journal of Case Reports in Surgery},

volume = {2},

issue = {1},

pages = {06-08},

abstract = {Background: Pancreatic pseudocysts are the most common cystic lesions of the pancreas. Surgical drainage remains the principal method of treating pseudocysts; its pre-eminance has recently been challenged. The introduction of innovative procedures both by the interventional radiologists and therapeutic endoscopists offer the (attractive) ability to drain pancreatic fluid collections non-operatively. Aim: To study the various treatment modalities and overall morbidity and mortality of pancreatic pseudocysts. Methodology: It was a prospective observational study. A study of 20 cases of pseudocysts of pancreas, who were subjected to various procedures, has been carried out between September 2010 to August 2012 at Deccan College of Medical Sciences, Hyderabad. Results: It is predominantly a disease of the elderly men with male to female incidence ratio 4:1. The commonest cause of pseudocysts of the pancreas in this study is chronic pancreatitis with prevalence of 60%. The commonest presentation is upper abdominal pain with upper abdominal mass. Serum

amylase levels are not much of value either in diagnosis or in follow-up treatment. The commonest site

is lesser sac and common cause in this situation being chronic pancreatitis. In all the cases it was confirmed that the cysts wall is deficient of epithelium by HPE. Cystogastrostomy was the commonest procedure done and the results were very good. Infection was the commonest complication. Mortality was nil. Conclusion: To conclude the in the present study, it was observed that the commonest cause was chronic pancreatitis and the commonest procedure done with good post-operative results was cystogastrostomy.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khajjayam_2019,

title = {Case of DU perforation with secondary omental necrosis- a rare case report},

author = {Radha Krishna Khajjayam and Bushra Khan and Atif Abdul Samee and Syed Mujtaba Ibrahim},

url = {https://www.ijmbs.info/index.php/ijmbs/article/view/757/624},

doi = {10.32553/ijmbs.v3i11.757},

issn = {2589-868X},

year  = {2019},

date = {2019-11-30},

urldate = {2019-11-30},

journal = {International Journal of Medical and Biomedical Studies},

volume = {3},

issue = {11},

pages = {129-131},

abstract = {Introduction: The Omentum is rich in blood supply. Omental Infarction can be classified as primary or secondary depending on the pathogenesis. Aims and Objectives: To report a case of DU perforation with secondary Omental Infarction. Case Details: A 21 year old male patient came with complaints of generalized dull aching abdominal pain, associated with persistent vomiting and high grade fever since 3 days. On examination, he was drowsy, BP was not recordable and peripheral pulses were not palpable. Abdominal examination revealed guarding and rigidity. X-ray erect abdomen showed gas under the right dome of the diaphragm (pneumoperitoneum). The patient was taken up for an exploratory laparotomy. Intraoperatively, findings included: 1) A 0.5*0.5cm in size perforation over the anterior first part of the duodenum, 2) approximately 3L of haemorrhagic peritoneal fluid 3) necrosed omentum and 4) petechial patches over the parietal wall of peritoneum. Primary repair of the DU perforation with omental plug (modified graham’s repair) with omentectomy of the necrosed part of omentum was done. The HPE report of excised specimen of omentum was suggestive of intense congestion and necro-inflammatory reaction of the omentum with necrosis and netrophilic infiltrate. Conclusion: A rare case of DU perforation with secondary omental necrosis is being reported. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Atharuddin_2019b,

title = {A study on complications, surgical management & its outcome with varicose veins in lower limbs},

author = {Athar Mohammed Atharuddin and Atif Abdul Samee},

url = {https://www.surgeryscience.com/articles/254/3-4-62-417.pdf},

doi = {10.33545/surgery.2019.v3.i4e.254},

issn = {2616-3462},

year  = {2019},

date = {2019-09-18},

urldate = {2019-09-18},

journal = {International Journal of Surgery Science},

volume = {3},

issue = {4},

pages = {275-278},

abstract = {Background: Varicose veins are a common clinical condition affecting the lower limbs. Usually patient

comes for a cosmetic problem; it can cause complications giving rise to significant morbidity if not treated

in time. Different options are available for surgical management. Aim & Objective: The present study mainly investigates the complications, surgical management and its outcome with varicose veins in lower limbs.

Methodology: We include 80 patients over a two year period all admitted patients to a Princess Esra Hospital, Shahali Banda, Hyderabad and Owasi Hospital and Research Centre, Kanchan Bagh, Hyderabad from period June 2017-June 2019. Results: In the present study showed long saphenous system involvement in 72.5% of cases. Majority of patients in the present series were patients of CEAP class 2 and 3 class. Almost 73.75 % had combined saphenofemoral and perforator incompetence. In the present study, underwent duplex USG evaluation for confirmation of diagnosis. This investigation was required to accurately diagnose 18 cases of

saphenofemoral incompetence, 10 cases of saphenopopliteal incompetence and 12 cases of perforator

incompetence. Most of the patients had wound infections followed by hematoma and residual varicosity.

Conclusion: From this study we conclude that commonest age group affected is 21-40 years. The involvement of long saphenous and communicating system is commonest followed by long saphenous involvement alone. Pain is the commonest symptom. Patients with involvement of longsaphenous and communicating system or long saphenous and short saphenous involvement were more symptomatic than the others. Commonest complication in post-operative treatment is wound infection. Complications of varicose veins responded well to operative treatment.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2019,

title = {A prospective study on etiology and clinical features of varicose veins: a hospital based study},

author = {Saif Mohammed Khan and Saniya Ahmed},

url = {https://www.surgeryscience.com/articles/209/3-4-1-111.pdf},

doi = {10.33545/surgery.2019.v3.i4a.209},

issn = {2616-3462},

year  = {2019},

date = {2019-09-17},

urldate = {2019-09-17},

journal = {Internationa3l Journal of Surgery Science},

volume = {3},

issue = {4},

pages = {06-10},

abstract = {Background: Varicose vein are abnormally dilated, tortuous, elongated veins of lower limbs which have

permanently lost their valvular efficiency. The main objectives of our study was to study etiological profile

(Age, sex, occupation and site pathology) and different modalities utilized in our institute and to assess and

study final outcome in patients included in our study. Methodology: It was a prospective study; fifty cases of varicose veins were attending outpatient Department and admitted in the Surgical Department of Deccan Medical College & Hospital from October 2018 to September 2019. Results: In the present study, fifty cases of varicose veins treated in our institute form the basis of this study. The average age of the patients was 41.86 years. The youngest patient was of 19 years and the oldest was 65 years of age. Varicose veins were common in males; the male to female ratio was 3.1:1. The number of patients who were involved in occupations requiring prolonged hours of standing was 35 (70%). A positive family history of varicose veins was present in only 4 cases (8%). Deep vein thrombosis was present in 7 patients (12.72%). The commonest presentation was dilated veins. The common associated symptoms were itching and pigmentation in 27 patients (54%) and ulceration in 13 patients (26%). 5 patients had bilateral varicose veins and the remaining 45 had only one limb affected. The limb commonly affected was right lower extremity in 29 cases (52.7%). Long saphenous vein was involved in 42 limbs (76.36%) and both long and short saphenous vein were affected only in 3 limbs (5.4%). Conclusion: The database of our retrospective study regarding age & sex incidence, clinicopathological features and therapeutic outcome was comparable to other studies in various literatures. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Atharuddin_2019,

title = {Study of prevalence, demographic & clinical manifestations of lower limb varicose veins},

author = {Athar Mohammed Atharuddin and Kondal Reddy J.},

url = {https://www.surgeryscience.com/articles/253/3-4-61-663.pdf},

doi = {10.33545/surgery.2019.v3.i4e.253},

issn = {2616-3462},

year  = {2019},

date = {2019-09-15},

urldate = {2019-09-15},

journal = {International Journal of Surgery Science},

volume = {3},

issue = {4},

pages = {272-274},

abstract = {Background: Varicose veins are a common condition that the current paper elaborates the features of the

condition in a local Indian population. Aim & Objective: The main aim of the present study to evaluate the prevalence, demographics and clinical manifestations of lower limb varicose veins patients. Methodology: We include 80 patients over a two year period all admitted patients to a Princess Esra Hospital, Shahali Banda, Hyderabad and Owasi Hospital and Research Centre, Kanchan Bagh, Hyderabad from period June 2017-June 2019. Results: In the present study, most of the patients (93.4%) were in the 20-50 years age group. Out of 80

patients, 70 patients were studied in their occupation and continuously involved in working and prolonged

standing showed muscular effect. We found that male (91.25%) patients were dominant than the female.

The right limb was involved in 18 cases and the left limb in 61 cases. The most common symptom was

pain with prominent veins which occurred alone or in combination with oedema, eczema, pigmentation or

ulceration. Conclusion: This study reveals that the disease is more prevalent during the active adult life in their 3rd and 4th decades and males were more affected. The occupations needing prolonged standing and use of

violent muscular efforts is found to be a contributing or precipitating factor for varicose veins. The commonest symptoms in the study were prominent swellings in the lower limb and pain. Definite relationship exists between occupation involving prolonged standing and primary varicose veins. The involvement of long saphenous and communicating system is commonest followed by long saphenous involvement alone.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ahmed_2019,

title = {A study on efficiency and sensitivity of evaluation and post-operative management of varicose veins: a prospective observational study},

author = {Saniya Ahmed and Saif Mohammed Khan},

url = {https://www.surgeryscience.com/articles/210/3-4-2-346.pdf},

doi = {10.33545/surgery.2019.v3.i4a.210},

issn = {2616-3462},

year  = {2019},

date = {2019-09-14},

urldate = {2019-09-14},

journal = {International Journal of Surgery Science},

volume = {3},

issue = {4},

pages = {11-17},

abstract = {Background: The present study was conducted with the aim to evaluate the clinical features and management of varicose veins in terms of recurrence and symptoms improvement. Methodology: It was a prospective study; fifty cases of varicose veins were attending outpatient Department and admitted in the Surgical Department of Deccan College of Medical Sciences & Hospital from October 2018 to September 2019. Results: In the present study, out of the 55 limbs examined and investigated, 7 limbs (12.72%) found to have suffered from deep vein thrombosis. Out of these 3 (5.4%) were found on clinical examination while investigations revealed deep vein thrombosis in 4 (7.2%) limbs. Routine investigations were carried out to evaluate patients’ fitness for surgery. Out of 50 patients 2 (5.5%) were unfit because of severe cardiac problem. The colour doppler study was done in all cases of which, in 12 cases (21.81%) an additional information was found. Out of these in two patient (16.66%) two perfortors missed on clinical examination was detected while in 6 patients (50%) additional information about perforator competency was found. Four patients have got additional information about deep vein patency. The accuracy of colour doppler in detecting SFJ and SPJ incompetence was 100%. By colour doppler, a total of 21 sites were marked as incompetent perforators, out of which 19 were found correct on exploration (90.47%specificity). Abdominal ultrasonography was performed in all patients. No abnormality was found in 49 of them while one had small left renal calculus. Various combinations of operations were carried out, according to the site of pathology determined by clinical examination and investigations. In our study, out of 55 limbs affected, only 14 limbs were operated upon. Out of 55 limbs, 41 were (74.54%) treated conservatively. Majority of them 29 were (64.1%) relieved of the symptoms by conservative method. From total 50 patients, 23 were treated on out Patients basis while 27 patients (46%) needed admission for either operative purpose or for ulcer healing. The average stay with 13 patients (45%) having ulcer was l5days. Stay was shorter in 14 patients (55%) who were not having ulcer, was average 11days. In the present study, only early post operative complications were noted in the post operative hospital stay in all the 14 patients, of this 1 patient (7.14%) developed wound infection. Only late post operative complications were noted during the follow-up period on outpatient basis. There were no mortalities noted in the intra-operative or the immediate

postperative period. Conclusion: A good clinical assessment with investigations, treatment of associated complications and a combination of surgical procedures have beneficial effects in minimizing cost and morbidity of varicose vein surgery.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Begum_2019,

title = {Abdominal wall tumours-primary or secondary: a case report},

author = {Rabiya Begum and Ganji Ravi and Syed Mujtaba Ibrahim},

url = {https://www.researchgate.net/publication/335860976_ABDOMINAL_WALL_TUMOUR-_PRIMARY_OR_SECONDARY_A_CASE_REPORT},

issn = {2349-2562},

year  = {2019},

date = {2019-08-31},

urldate = {2019-08-31},

journal = {Journal of Evidence Based Medicine and Healthcare},

volume = {6},

issue = {32},

pages = {2195-2197},

abstract = {60-year-old male patient, farmer by occupation, with no comorbidities presented with recurrent abdominal swelling of 4 years duration with history of pain in the swelling since previous 2-3 months. He was earlier operated for a swelling at the same site 7 years before in a hospital in a neighbouring small town. Neither the details of that procedure were available, nor it was known the specimen was sent for histopathological examination or not.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sharma_2019,

title = {Consensus on the management of posterior urethral valves from antenatal period to puberty},

author = {Shilpa Sharma and Manoj Joshi and Devendra K. Gupta and Mohan Abraham and Praveen Mathur and J. K. Mahajan and A. N. Gangopadhyay and Simmi K. Rattan and Ravindra Vora and G. Raghavendra Prasad and N. C. Bhattacharya and Ram Samuj and K. L. N. Rao and A. K. Basu},

url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322183/?report=reader},

doi = {10.4103/jiaps.JIAPS_148_18},

issn = {0971-9261},

year  = {2019},

date = {2019-03-31},

urldate = {2019-03-31},

journal = {Journal of Indian Association of Pediatric Surgeons},

volume = {24},

issue = {1},

pages = {4-14},

abstract = {The need for successful management of posterior urethral valves always captivates the minds of pediatric surgeons. Its success, however, depends on several factors ranging from prenatal preservation of upper tracts to postoperative pharmacological compliance. Regardless of measures available, some cases do not respond and progress to end stage. The management depends on several issues ranging from age and severity at presentation to long-term follow-up and prevention of secondary renal damage and managing valve bladder syndrome. This article is based on a consensus to the set of questionnaires, prepared by research section of Indian Association of Paediatric Surgeons and discussed by experienced pediatric surgeons based in different institutions in the country. Standard operating procedures for conducting a voiding cystourethrogram and cystoscopy were formulated. Age-wise contrast dosage was calculated for ready reference. Current evidence from literature was also reviewed and included to complete the topic.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2018b,

title = {Clinical examination for complex fistula in ano: relevance in present times-a clinical study},

author = {Bushra Khan and Nikhilesh Vedire and Ismail Khan and Akshan Ugale and Ganji Ravi and Mohammed Abdul Hadi},

url = {https://www.apjhs.com/index.php/apjhs/article/view/271/231},

doi = {10.21276/apjhs.2018.5.3.9},

issn = {2349-0659},

year  = {2018},

date = {2018-09-30},

urldate = {2018-09-30},

journal = {Asian Pacific Journal of Health Sciences},

volume = {5},

issue = {3},

pages = {67-76},

abstract = {Background: Fistula in Ano has been known as a chronic painful disease since centuries past with no proven well defined course of management even till the present times. This has given rise to various forms of treatment ranging from seton to flaps. Materials and Methods: Total 83 adult patients with age ranging from 16 to 70 years were studied over a span of 8 years starting from Jan‟10 to Dec‟17. Clinical findings were compared with MR Imaging and correlated with Intraoperative Methylene blue injection. The findings were tabulated and compared regarding effectiveness of each method in determining the exact anatomy of the fistula and statistical significance was determined by Chi square test. Results: Our studies showed that the chances of detecting the internal opening by clinical examination is significantly better than MRI, however neither clinical examination nor MRI is a full proof mechanism for detecting the type of fistula. Conclusion: Even though Imaging is better at detecting the fistula anatomy there is still a role for a proper clinical examination in outpatient department. Clinical Examination compares favorably with MR Imaging in detecting Internal Opening of a Fistula. Even in complicated Fistulas, a proper clinical examination is better than Imaging in detection of anatomy of a fistula, even though there is no statistically significant difference between the two methods.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Prasad_2018b,

title = {Early enteral nutrition in neonates following abdominal surgery},

author = {G. Raghavendra Prasad and J. V. Subba Rao and Amtul Aziz and T. M. Rashmi and Saniya Ahmed},

url = {https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/384/pdf},

doi = {10.21699/jns.v7i2.740},

issn = {2226-0439},

year  = {2018},

date = {2018-04-08},

urldate = {2018-04-08},

journal = {Journal of Neonatal Surgery},

volume = {7},

issue = {2},

pages = {21},

abstract = {Introduction: Nil per oral (NPO)/nil by mouth has been the most commonly practiced convention in post-operative period. Misplaced fear of aspiration led to routine prescription of “NPO.” Starvation leads to atrophy of the gut mucosa leading to decreased barrier effect of gut mucosa. This starvation-induced gut mucosal injury increases septic complications and mortality. The study aims at establishing the feasibility and effect of early enteral nutrition (EEN) in neonates following abdominal surgeries. Materials and Methods: A total of 260 cases formed the cohort of prospective cohort study, 79 in EEN - Group “A” and 181 in NPO - Group “B.” Effect of EEN was evaluated with regard to outcome, hospital stay, surgical site infections (SSI), stress markers such as C-reactive protein (CRP), procalcitonin, tumor necrosis factor alpha (TNF α), and neonatal-predisposition, insult/injury, response, organ failure (Neo-PIRO) scores, intra-abdominal pressure (IAP) grade, tolerance of feeds, and time to first stool. Chi-square was the statistical method used. Epi info version 7 was the software used. Results: Group B had higher mortality (20.09%) than Group A (P < 0.05). 33.7 in Group B developed SSI, of which 90% were deep and intracavitary (P < 0.05). Hospital stay was less in Group A (P < 0.05). CRP and Neo-PIRO scores were less in Group A compared to Group B (P < 0.05). TNF-α expression and IAP scores were not statistically significant (P > 0.05). Procalcitonin levels were higher in Group B. Feeds were better tolerated in Group A. First stool appeared earlier in Group A than B. There was no difference in anastomotic leak in both the groups. Conclusion: EEN in neonates following abdominal surgeries is feasible, well tolerated reduces the hospital stay and mortality, and reduces SSIs, and early gut motility could be established.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan_2018c,

title = {Riedel's thyroiditis presenting as large retropharyngeal goitre-a rare case},

author = {Bushra Khan and Ganji Ravi and Bhima Linga Prasad},

url = {https://www.apjhs.com/index.php/apjhs/article/view/886/773},

doi = {10.21276/apjhs.2018.5.1.33},

issn = {2349-0659},

year  = {2018},

date = {2018-03-30},

urldate = {2018-03-30},

journal = {Asian Pacific Journal of Health Sciences},

volume = {5},

issue = {1},

pages = {150-152},

abstract = {The thyroid gland lies in the anterior triangle of the neck in close approximation to the larynx and the trachea. The extension of an enlarged thyroid gland outside the normal confines of the thyroid bed is well known. A 35-year-old woman presented with a 12-year history of swelling in the midline of the neck which progressively increased in size and was currently associated with symptoms of dysphagia, difficulty in breathing, and hoarseness of voice. Physical examination revealed an ill-defined neck swelling moving on deglutition, with a bosselated surface with no overlying skin changes. Contrast-enhanced computed tomography scan of the neck revealed para- and retro-pharyngeal goiter with extension up to base of the tongue. Retropharyngeal extension of goiter is thought to be a rare entity in itself as shown in literature, but a large retropharyngeal goiter in Riedel’s thyroiditis has not been described before and seems to depend mainly on the body habitus of the patient.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ravi_2017,

title = {Gossypiboma: an enigma},

author = {Ganji Ravi and Nikhilesh Vedire and Mohammed Abdul Hadi and Syed Nusrath Farees and Venkat Naveen Reddy M.},

url = {https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/fileview.php?val=December_2017_1512223653__266.pdf},

doi = {10.36106/ijsr},

issn = {2277-8179},

year  = {2017},

date = {2017-12-31},

urldate = {2017-12-31},

journal = {International Journal of Scientific Research},

volume = {6},

issue = {12},

pages = {381-384},

abstract = {Retained surgical sponge in the body following surgery though not as common in the present times as in the pre laparoscopic era, when laparotomies were routinely done for abdominal pathology is still a much feared entity mainly from the surgeons point of view as it is a sure shot way to infamy legal tangles and financial troubles if discovered in unfavourable circumstances. What we have endeavoured to find out in our study

of five gossypiboma cases which we have encountered in past 12 years and review of past cases published on this subject is – does the operating surgeon has any control over the unfolding events post inadvertent retention of the foreign body. DISCOVERIES One patient had a gauge piece tucked away behind the strap muscles, two patients were found with intraluminal migration of surgical sponge - one complete (tightly coiled). One incomplete (into jejunum and ileum). Two were discovered with sponge encapsulated between dense intestinal and bladder adhesion, one in the process of dissolution and another completely dissolved into abscess cavity without any bowel injury. CONCLUSION Heed patients complaints and have a high degree of suspicion when dealing with post op patients even when they complain of vague symptoms. These and quite a little bit of luck is required in surgical practise to help the surgeon stay clear of dangerous situations. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kumar_2017,

title = {Clincial relevance of MMP-9 in terms of neoplasm growth, invasion and metastasis in thyroid, breast and colorectal cancer},

author = {V. Hari Kumar and Omar Bin Hasan },

url = {https://www.ijsurgery.com/index.php/isj/article/view/2076/1665},

doi = {10.18203/2349-2902.isj20175408 },

issn = {2349-2902},

year  = {2017},

date = {2017-11-25},

urldate = {2017-11-25},

journal = {International Surgery Journal},

volume = {4},

issue = {12},

pages = {4049-4053},

abstract = {Background: Cancer cells invade and metastasis commonly. This poses challenge in cancer management. MMP-9 can be clinically useful to predict the prognosis of the patients. Objective was to study clinical relevance of MMP-9 in terms of neoplasm growth, invasion and metastasis in Thyroid, Breast and Colorectal cancer.

Methods: A hospital based cross sectional study was carried out in Department of General Surgery, Kamineni Institute of Medical Sciences, Narketpally for a period of two years. A total of 30 cases of carcinoma cases were studied. Out of these carcinoma cases, 10 were of gastrointestinal malignancy, 10 were of thyroid malignancy and 10 were of breast carcinoma. Results: For breast carcinoma, maximum cases were in the age group of 46-50 years (40%), for thyroid carcinoma, maximum cases were seen in the age group of more than 55 years (40%), for colo-rectal carcinoma, maximum cases were above the 50 years of age. For breast carcinoma, maximum cases were in stage III B (70%), for thyroid carcinoma, in III stage (60%) and for colo-rectal carcinoma, in Dukes C1 stage (60%). In breast cancer the positivity of MMP-9 was 66.7% in stage IIIA and it increased to 85.7% in stage IIIB. For thyroid cancer the positivity increased from 33.3% in stage III to 75% for stage IV A. In case of colo-rectal cancer, the positivity of MMP-9 expression increased from 66.7% for stage Dukes C 1 to 75% in stage Dukes C2 stage. Thus, for all types of carcinoma, the expression of MMP-9 increased with advancement of the stage. Conclusions: MMP-9 is a gelatinase which degrades extra cellular matrix and helps in tumor spread. It is expressed more in advanced stages of the malignant disease. It correlates with prognosis of the patient.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Moghadam_2017,

title = {Pattern of dynamic intestinal obstruction in adults},

author = {Abdul Ghader Barazaneh Moghadam and Syed Asif Shah Harooni},

url = {https://www.iaimjournal.com/storage/2017/10/iaim_2017_0410_35.pdf},

issn = {2394-0026},

year  = {2017},

date = {2017-10-11},

urldate = {2017-10-11},

journal = {International Archives of Integrated Medicine},

volume = {4},

issue = {10},

pages = {230-235},

abstract = {Background: In aboral direction, when the intestinal contents cannot be forced further, a situation arises known as intestinal obstruction. Aim: Aim was to evaluate the common causes of intestinal obstruction. Methods and materials: This study was a retrospective study which was conducted from January 2015 to April 2017 in Department of Surgery in Deccan College of Medical Sciences Hyderabad. This study consisted of 60 patients who were admitted in department of surgery who were presented with acute intestinal obstruction and patients who underwent operative management were included in the study. The patients who conservatively managed the obstruction and who were below 12 years of age were excluded from the study. Results: 60 patients underwent management operatively during the two years duration with the paediatric group excluding from the study (age below 12 years) and others got treatment conservatively. Males were more compared to female patients who constituted 39 (65%) males and 21 (35%) females. The most common occurrence of intestinal obstruction was in the age group of 42-51 years (33.3%). The most common presenting complaint is abdominal pain. The most common type of bowel obstruction is small intestine. Adhesion and band is the most common cause of intestinal obstruction 25 (41.6%), followed by Malignancy 15 (25%), obstructed hernia 5(8.3%),

Volvulus 5 (8.3%), Stricture 4 (6.6%), Ileac tuberculosis 2 (3.3%), SMA thrombosis 2 (3.3%), superior mesenteric artery thrombosis 2 (3.3%). The most common type of surgery was adhesiolysis which constituted 20 (33.3%) followed by Resection and ostomy which constituted 10 (16.6%). The most common post-operative complication was wound infection which constituted 18 (30%). Conclusion: The most common cause of bowel obstruction is adhesive intestinal obstruction followed by malignant bowel obstruction. Early diagnosis, perioperative management and general condition of patients are keys in the successful management of acute intestinal obstruction.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ravi_2017b,

title = {Flap closure for gluteal pilonidal sinus-is it an economically viable option?},

author = {Ganji Ravi and Akshan Ugale and Nikhilesh Vedire and Soumya Chauhan and Prasad B. L. Ch. and Ali Mohammed Syed},

url = {https://www.jebmh.com/articles/flap-closure-for-gluteal-pilonidal-sinus-is-it-an-economically-viable-option.pdf.pdf},

doi = {10.18410/jebmh/2017/777},

issn = {2349-2562},

year  = {2017},

date = {2017-08-11},

urldate = {2017-08-11},

journal = {Journal of Evidence Based Medicine and Healthcare},

volume = {4},

issue = {65},

pages = {3889-3894},

abstract = {BACKGROUND: Flap closure technique for sacrococcygeal pilonidal sinus disease has been conclusively shown to be effective in relieving recurrence rate in many studies, but it is expensive and difficult to perform. Purpose of this study is to find out if simple primary closure is effective in management as claimed by some authors and to determine which of the procedures is easier on the pocket for the patient.

MATERIALS AND METHODS: Patients were enrolled into either of the two groups- Group A- Simple primary closure. Group B- Flap closure and gluteal sulcus obliterative procedures based on their choice after explaining the type of procedure and the approximate cost involved in both. Parameters recorded and analysed by Pearson’s Chi-square test for statistical significance.

RESULTS: 95 patients were included for the study- 42 in Group A and 53 in Group B. Male-to-female ratio of 5:2 and 11:4, respectively; average age of 25 in both the groups (range 15 to 40 years in group A, 16 to 41 in group B). There were 17 wound dehiscence, 2 seromas and 7 recurrences in group A and 16 wound dehiscence, 8 seromas and 2 recurrences in group B. The difference is the recurrence rate being statistically significant. 12 patients- 8 with non-healing wounds and 4 with recurrences from group A joined group B while 9-6 with dehiscence and 3 recurrences were lost to follow up. Average wound healing time in the simple closure patients was 31 days, while in group B, it was 16.4 days. Average expenditure incurred by patients in primary closure group was Rs. 7,900 compared to Rs. 9,300 in group B, but if the additional expense due to crossing over to group B was added, average jumped up to Rs. 10,700, which was Rs. 1000 more than the flap closure patients.

CONCLUSION: In management of patients with chronic sacrococcygeal pilonidal sinus, even though the average cost of treatment by simple primary closure is less than that by flap closure technique, the significantly higher rate of recurrence and prolonged time to heal in case of wound dehiscence nullifies whatever pecuniary benefits they may have gained and hence flap closure is advisable especially in patients with recurrent disease.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}