@article{Shaik_2024c,

title = {Cervicomedullary compression in achondroplasia: a feared complication and an unforeseen risk factor of posterior circulation stroke},

author = {Reshma Sultana Shaik and Sandhya Manorenj and Sravan Kumar Marupaka},

url = {https://journals.lww.com/neur/fulltext/2024/72020/cervicomedullary_compression_in_achondroplasia__a.31.aspx},

doi = {10.4103/ni.ni_537_21},

issn = {0028-3886},

year  = {2024},

date = {2024-04-30},

urldate = {2024-04-30},

journal = {Neurology India},

volume = {72},

number = {pmid38691484},

issue = {2},

pages = {399-402},

abstract = {Achondroplasia is an autosomal dominant disorder with defect in the ossification of the cartilage of long bones. Many bony abnormalities constitute its clinical features, with craniovertebral junction (CVJ) anomalies being one of most common issues which need to be addressed at the earliest. CVJ anomalies in individuals may cause neurovascular compression, which may warrant an early surgery to prevent catastrophic complications. Posterior circulation strokes secondary to CVJ anomalies are well known. We hereby present an unusual case of posterior circulation stroke in an achondroplastic dwarf who presented to our tertiary care centre. Prospective case study. The present case adds to the existing literature about one of the preventable causes of fatal posterior circulation strokes in the young. A high index of suspicion for neurovascular compression at the foramen magnum and early initiation of treatment in achondroplastic young individuals may have gratifying results.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shaik_2024b,

title = {Acute Necrotizing Encephalopathy of Childhood (ANEC) in a patient with dengue and leptospirosis},

author = {Reshma Sultana Shaik and Sandhya Manorenj and Sravan Kumar Marupaka},

url = {https://journals.lww.com/neur/fulltext/2024/72020/acute_necrotizing_encephalopathy_of_childhood.43.aspx},

doi = {10.4103/ni.ni_984_21},

issn = {0028-3886},

year  = {2024},

date = {2024-04-30},

urldate = {2024-04-30},

journal = {Neurology India},

volume = {72},

number = {pmid38691496},

issue = {2},

pages = {433-434},

abstract = {None},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Manorenj_2024c,

title = {A neurologist’s perspective of approach to falls in the elderly},

author = {Sandhya Manorenj and Reshma Sultana Shaik},

url = {https://journals.lww.com/aomd/fulltext/2024/07010/a_neurologist_s_perspective_of_approach_to_falls.2.aspx},

doi = {10.4103/aomd.aomd_56_22},

issn = {2590-3446},

year  = {2024},

date = {2024-04-29},

urldate = {2024-04-29},

journal = {Annals of Movement Disorders},

volume = {7},

issue = {1},

pages = {3-12},

abstract = {Falls constitute an important public health problem that impact the quality of life of an individual. Falls contribute to disability, especially among older adults and elderly individuals. Recurrent fallers are those who fall one or more times per year. The purpose of this article is to provide a detailed systemic qualitative review of the recent definition of falls, their mechanism, risk factors, classification; falls in neurodegenerative disorders; and their approach and management. Sources of literature were drawn from peer-reviewed original and systematic review articles published until January 2024 in the PubMed database using the following key words: falls, elderly, definition, management, etiology, neurodegenerative diseases, epilepsy and fall, dementia and fall, and prevention and diagnostic tests for postural instability and falls. This review summarizes the current understanding of falls and provides a pragmatic and clinically focused approach to their management. Falls are usually multifactorial. Neurodegenerative disorders such as cognitive decline and parkinsonism lead to increased risk of falling. There are several tools to assess the risk of early falls. A multidisciplinary approach is needed in the management of falls. The main goal is encouraging physical activity, home hazard modification, management of postural hypotension, and underlying neurodegenerative diseases.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hyder_2024,

title = {Effect of smartphone usage during night time on sleep patterns of young adults: A cross-sectional observational study},

author = {Safa Hyder and Sudhir Shankar Mane and Mohammed Abdul Hannan Hazari and Mehnaaz Sameera Arifuddin},

url = {https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2024&month=April&volume=18&issue=4&page=CC01&id=19291},

doi = {10.7860/jcdr/2024/66874.19291},

issn = {0973-709X},

year  = {2024},

date = {2024-04-01},

urldate = {2024-01-01},

journal = {Journal of Clinical and Diagnostic Research},

volume = {18},

issue = {4},

pages = {CC01-CC06},

publisher = {JCDR Research and Publications},

abstract = {Introduction: Excessive smartphone usage among adolescents and young adults has been consistently linked to poor sleep. Moreover, smartphone overuse has been associated with daytime tiredness, longer sleeps latency, and reduced sleep duration. The significance of addressing poor sleep among adolescents and young adults is underscored by recent research linking it to adverse physical and psychological health outcomes, such as mood disturbances, impaired cognitive function, and increased risk incidence of hypertension and diabetes.

Aim: To evaluate the effects of smartphone usage on sleep quality among individuals using Pittsburgh Sleep Quality Index (PSQI) and hypnogram data.

Materials and Methods: In this cross-sectional observational study, sleep patterns were assessed using the PSQI questionnaire and Prime Nap sleep tracker app (version 1.1.4). The study was conducted by Deccan College of Medical Sciences, Hyderabad, Telangana, India. The data was collected in the form of a hypnogram and the study was conducted in the participants’ homes (under domicile conditions) in the city of Hyderabad, Telangana, India from March 2020 to April 2020. A total of 60 participants (both male and female) in the age group of 15-25 years were recruited and divided into two groups: one comprising 30 individuals with regular prolonged exposure to smartphone screens at night, and the other consisting of 30 individuals who experienced minimal or no smartphone exposure once they prepared to sleep. Descriptive statistics were applied to the collected data using Microsoft Excel and IBM Statistical Package for Social Sciences (SPSS) for Windows version 25.0.

Results: Adding up the average scores of the seven factors gives a global PSQI score from 0 to 21, with 0-4 indicating good sleep and 5-21 indicating poor sleep. Among those who used smartphones regularly at night time, 20 participants (66.67%) had PSQI score >5 and poor sleep quality, 24 participants (80%) had prolonged sleep latency, 18 participants (60%) had poor sleep duration, 27 participants (90%) had sleep disturbances, and 22 participants (73.33%) had increased daytime dysfunction. Hypnogram abnormalities were seen in >15 participants (50%) of subjects.

Conclusion: The prevalence of smartphone addiction is widely acknowledged in the medical literature, highlighting the need for its assessment, especially among adolescents and young adults. The study reveals that poor sleeping habits among participants were attributable either to a lack of awareness or neglect. By recognising the importance of adequate sleep, improvement in the quality of daily activities can be made by reducing daily screen time, consequently alleviating both physical and mental stress. Furthermore, the findings have implications for individuals whose work involves prolonged exposure to computer screens, especially during night time.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zoheb_2024,

title = {High blood pressure, hyperlipidemia, type 2 diabetes with prior history of atrial fibrilation caused stroke},

author = {Mohammed Zoheb and Deeba Rana and Shaikh Mahmood},

url = {https://www.worldwidejournals.com/international-journal-of-scientific-research-(IJSR)/article/high-blood-pressure-hyperlipidemia-type2-diabetes-with-prior-history-of-arterial-fibrilation-caused-stroke/NTUzMDY=/?is=1&b1=&k=},

issn = {2277-8179},

year  = {2024},

date = {2024-04-01},

journal = {International Journal of Scientific Research},

volume = {13},

issue = {4},

pages = {1-2},

abstract = {The stroke cases are on rise, to know its causes, symptoms & treatment patients have to be studied in detail and get the appropriate result. Stroke is a serious medical condition that can sometimes be deadly. Stroke cases are emerging at a startling rate at the moment. People with specific medical problems are more susceptible to stroke, even though it may affect anybody. A stroke or brain stroke can be fatal and result from inadequate blood supply to a portion of the brain, according to the Cleveland Clinic. The most common causes of this are cerebral hemorrhage or arterial obstruction. If insufficient blood flow occurs, oxygen-starved brain cells begin to die. A stroke may happen to anybody, at any age, although certain people are more susceptible than others. Furthermore, beyond the age of 65, the danger rises. Strokes occur commonly in either sex. Strokes are the second largest cause of mortality worldwide. Not only that, but stroke is a leading global cause of disability. The following are a few examples of stroke symptoms paralysis on one sides peaking difficulties or loss of speech distorted or double vision (diplopia) inability to coordinate light headedness

and vomiting stiff neck personality shift agitation or confusion seizure loss of memory headache loss of consciousness the blood clotting disorder atherosclerosis Heart abnormality (ventricular or atrial septal defect) microvascular ischemia elevated blood pressure tumors of the brain (including cancer)Heart abnormality (ventricular or atrial septal defect) microvascular ischemia elevated blood pressure tumors of the brain (including cancer) etc.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Fatima_2024,

title = {To explore the effectiveness of problem-based learning over conventional didactic lecture in microbiology for phase 2 MBBS students},

author = {Sarwat Fatima and Mohammed Sarosh Ahmed and Madhipati Sai Krishna and Maimoona Mustafa and Shahbaz Sajjad},

url = {https://www.iosrjournals.org/iosr-jrme/papers/Vol-14%20Issue-1/Ser-2/D1401022630.pdf},

doi = {10.9790/7388-1401022630},

issn = {2320–737X},

year  = {2024},

date = {2024-02-20},

urldate = {2024-02-20},

journal = {IOSR Journal of Research & Method in Education},

volume = {14},

issue = {1 (Series 2)},

pages = {26-30},

abstract = {Background:Problem based learning [PBL] has been identified and approved by many medical educationists

as one of the best teaching learning methods due to the fact that it improves students’ learning in all 3 domains and improves higher order thinking. Research has found its positive effect to be variable in different geographic settings. Aim & objectives: To explore the effectiveness of PBL over conventional lecture. To evaluate students’ performance using PBL rubrics. To determine student’s acceptance and perceptions of PBL.

Material& methods: the present study is a prospective experimental and interventional type. The IERB approval was obtained and project was pilot tested. Study participants were enrolled by verbal consent and sampled using quota and randomisation method. The sequential steps of the study include: orientation on PBL method, pre-test, a questionnaire on preparedness for self-directed learning [SDL], conduct of sessions by 2 different TL methods with exchange of groups, post-test, students grading and lastly general feedback. Statistical methods: Mean ± SD, unpaired t test and 5-point Likert scale was used for analysis of results. Results: Around 114 /147 [77.55%] enrolled and continued till the end. The overall mean scores for DL & PBL method of teaching were as 1.65 ± 0.53 & 1.70 ± 0.62 in pre-test and 6.84 ± 1.22 and 7.36 ± 1.07 in post-test with p values as 0.178 & 0.118. For individual topics in post-test the PBL group secured higher scores than DL except for one. The assessment and feedback on PBL gave variable results. Discussion &Conclusion: the present study couldn’t find any statistically significant difference in the learning outcomes while using 2 different TL methods. However, the questionnaire on SDL preparedness, assessment and feedback data revealed certain grey zones which demand further enquiry into students learning plans & preferences which could be one of the reasons for the outcome observed and open doors for future qualitative research. Limitations: students and faculty related factors besides study design might have influenced the outcomes observed. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Manorenj_2024b,

title = {Ictal nystagmus in a patient with nonketotic hyperglycemia: a rare clinical phenomenon of occipital epilepsy},

author = {Sandhya Manorenj and Deepika Venniveli and Mounika E. Reddy and Srujana Billa},

url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10941902/pdf/AIAN-27-77.pdf},

doi = {10.4103/aian.aian_800_23},

issn = {0972-2327},

year  = {2024},

date = {2024-02-06},

urldate = {2024-02-06},

journal = {Annals of Indian Academy of Neurology},

volume = {27},

number = {pmid38495234},

issue = {1},

pages = {77-79},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ali_2024,

title = {Knowledge of stroke and the window period for thrombolytic therapy in ischemic stroke among South Indians: a hospital-based survey with educational intervention},

author = {Reem Jaffer Ali and Sandhya Manorenj and Ruqya Zafar},

url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10927053/?report=printable},

doi = {10.25259/JNRP_312_2023},

issn = {0976-3147},

year  = {2024},

date = {2024-02-05},

urldate = {2024-02-05},

journal = {Journal of Neurosciences in Rural Practice},

volume = {15},

number = {pmid38476435},

issue = {1},

pages = {111-116},

abstract = {Objectives: The objective of this study was to determine the awareness of stroke in regards to the risk factors, warning symptoms, and knowledge of the therapeutic window period among varied strata of non-medical people attending a tertiary care center.

Materials and Methods: The interventional study involved the collection of data regarding awareness of stroke using a structured questionnaire with a total score of 16. Pre-intervention assessment was followed by intervention in the form of education regarding awareness of stroke administered one-on-one for personalized and effective comprehension by subjects. Then, subjects were asked to recall the information that was delivered to them and were scored accordingly.

Results: Among the 500 subjects included, 51% were female. About 76.8% of participants were young (age <50 years), and 83.4% were literate. Only 25.4% of participants were aware of the brain as the site of stroke. About 32.2% of candidates were aware of a few risk factors for stroke. Among them, the majority of participants were aware of hypertension (24%) as a risk factor. The most known warning symptom was “Numbness” or weakness of arm. The majority of the subjects (97.8%) were unaware of a therapeutic window period for stroke being 4.5 h or below. The mean pre-intervention score was 2.52 ± 1.65 while the mean post-intervention score was 15.10 ± 1.79 (P < 0.0001).

Conclusion: The study showed that even among literate participants, only a meager number of subjects were aware of the golden window period of intravenous thrombolysis. Educational intervention by means of an in-person and one-on-one explanation achieved significant levels of understanding of stroke. The study could be used to formulate large-scale educational programs that focus on spreading awareness of symptoms and risk factors while also instilling the importance of timely medical intervention for efficient thrombolytic therapy.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Samiuddin_2024,

title = {An investigation of the antibiotic sensitivity of peritoneal fluid cultures in cases of perforative peritonitis},

author = {Md. Samiuddin and M. R. Madhu Mohan Reddy and Mallika Anjum},

url = {https://www.jcdronline.org/admin/Uploads/Files/65b63b946af163.82910711.pdf},

doi = {10.48047/jcdr.2024.15.01.222},

issn = {0975-3583},

year  = {2024},

date = {2024-01-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {15},

issue = {1},

pages = {1982-1989},

abstract = {Introduction: Peritonitis is a prevalent issue encountered by General surgeons. Significant advancements in the treatment of peritonitis have occurred in recent decades, primarily through the utilisation of antibiotics and surgical interventions. The objectives of the study were to ascertain the antibiotic sensitivity and resistance pattern for routinely utilised antibiotics against the cultured microbes. Material and Methods: This study was conducted using a cross-sectional design. The research was carried out at the Department of General Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India. The study was done from October 2022 to September 2023. This study utilised a sample of 40 persons as subjects. Result: A common complication of perforation of the hollow viscus is secondary peritonitis. Because patients sometimes do not arrive at the hospital until much later, the fatality rate is significant. The age groups of 31–40 years old and 20–30 years old accounted for the bulk of the perforation cases in our study. The average age at which symptoms first appear is 35.26 years. Based on our findings, the second half of the duodenum accounts for 52% of perforations, whereas the stomach accounts for 42%. Among the organisms developed, Klebsiella accounted for 46% of the cases, E. coli for 34%, and just 2% displayed a combination of the two. Our study focused on analysing the sensitivity patterns of organisms that were cultivated. Ceftriaxone, ciprofloxacin, and amikacin were the most commonly found organisms that demonstrated sensitivity. Conclusion: The study found that the most common site of perforation is the duodenum, followed by the stomach. Peptic ulcer illness was the most common cause. The most common bacteria responsible for secondary peritonitis in these patients were Klebsiella and Escherichia coli, with mixed, proteus, and pseudomonas infections occurring very rarely. Cephalosporins, quinolones, and macrolides were the most effective antibiotics against Klebsiella and Escherichia coli, in that order of sensitivity.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Reddy_2024,

title = {Evaluation of the pathological response to neoadjuvant chemotherapy in locally advanced breast cancer},

author = {M. R. Madhu Mohan Reddy and Yasaswi Ponnapalli and Md. Samiuddin},

url = {https://www.jcdronline.org/admin/Uploads/Files/65b639bdbf1688.07599035.pdf},

doi = {10.48047/jcdr.2024.15.01.218},

issn = {0975-3583},

year  = {2024},

date = {2024-01-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {15},

issue = {1},

pages = {1952-1958},

abstract = {Background and objective: To assess how patients with locally advanced breast cancer respond pathologically to neoadjuvant therapy. It is uncommon to have locally advanced breast cancer (LABC), and it poses significant clinical challenges. The purpose of the study was to look into the relationship between disease-free survival and the pathological response to neoadjuvant chemotherapy. Method: An observational study was conducted at Department of General Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India from December 2022 to November 2023. on a sample of 40 persons to assess the pathological response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. The study received ethical approval from the committee. Result: Between the ages of 50 and 60, 33% of the population fell. About half of the patients exhibited negative human epidermal growth factor receptor 2 (HER2), positive progesterone receptor (PR), and positive oestrogen receptor (ER). Sixty-seven percent of tumours tested positive for both the progesterone receptor (PR) and the oestrogen receptor (ER). Forty percent of the tumours had HER2 positive results. Merely 17% of the patient cohort exhibited a pathological reaction to neoadjuvant chemotherapy (NACT). 83% of the total did not respond.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Murthy_2024,

title = {To study down staging locally advanced breast carcinoma: The role of neoadjuvant chemotherapy},

author = {T. S. R. Murthy and Mohammed Arshad Ali Khan and M. R. Madhu Mohan Reddy},

url = {https://www.jcdronline.org/admin/Uploads/Files/65b639291f0728.16145573.pdf},

doi = {10.48047/jcdr.2024.15.01.217},

issn = {0975-3583},

year  = {2024},

date = {2024-01-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {15},

issue = {1},

pages = {1944-1951},

abstract = {Introduction: Although rare, locally progressed breast cancer is a major obstacle for clinicians. This study was conducted because there is a direct correlation between the pathological response to neoadjuvant chemotherapy and disease free survival. This study was out to evaluate the histological impact of neoadjuvant chemotherapy on breast cancer patients with locally advanced disease. Material and Methods: This study was observational based study. The research was carried out at the Department of General Surgery, Deccan College of Medical Sciences, Hyderabad, Telangana, India. The study was done from September 2022 to July 2023. A total of twenty-five people were used as subjects in this research. Modified radical mastectomy was performed after clinical evaluation of tumour response and patient follow-up. Pathological reaction was assessed and notes were made on the specimen. Result: People in their 50s and 60s made up the bulk of the population. The majority of the 30 patients with locally advanced cancer (73%), ranging from stage IIIA to stage IIIB, were men.Nearly half of the patients tested positive for oestrogen receptors but negative for HER2, and a quarter of those individuals tested positive for all three.Everyone who tested positive for HER 2 was also considered to be a triple negative. Both the ER and PR positive tumour percentages were 67%.Forty percent of tumours tested positive for HER2. Possible explanations for the low response rate and high rate of ER positive include the fact that 83% of patients did not react to NACT and only 17% demonstrated a pathological response. Conclusion: Better prognosis may be possible if we could determine which tumours would respond best to which treatments. Recent developments in cancer biology and genetic profiling have the potential to revolutionise the clinical management of LABC by allowing for a more targeted and personalised approach.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shaik_2024,

title = {Usual to unusual vascular complications encountered during endovascular management of renal biopsy complications},

author = {Zoya Shaik and Sravan Kumar Marupaka and Jampala Venkateshwarlu},

url = {https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/article/usual-to-unusual-vascular-complications-encountered-during-endovascular-management-of-renal-biopsy-complications/MjgxODc=/?is=1},

doi = {10.36106/gjra/5107582},

issn = {2277-8160},

year  = {2024},

date = {2024-01-15},

urldate = {2024-01-01},

journal = {Global Journal for Research Analysis},

volume = {13},

issue = {1},

pages = {136–137},

publisher = {World Wide Journals},

abstract = {Percutaneous renal biopsy is widely used for diagnosis, prognosis, and management of nephropathies. Early identification and embolization of the involved artery aids in effective management of the vascular complications and defers the need for nephrectomy. In this study, we aimed to evaluate various vascular injuries after renal biopsy requiring interventions. Pseudoaneurysm was the most common form of arterial injury. Target vessel was identified by angiography and successful embolization was done deferring nephrectomy. Deaths occurred due to hemorrhage.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ahmed_2024,

title = {A comprehensive analysis of clinical characteristics, microbial profile, prognostic indicators, and treatment in patients with type 2 diabetes mellitus and acute pyelonephritis},

author = {Syed Faiz Ahmed and Mohammed Khaja Arifuddin},

url = {https://www.jcdronline.org/admin/Uploads/Files/659e8cded4aae5.77075932.pdf},

doi = {10.48047/jcdr.2024.15.01.55},

issn = {0975-3583},

year  = {2024},

date = {2024-01-11},

journal = {Journal of Cardiovascular Disease Research},

volume = {15},

issue = {1},

pages = {496-505},

abstract = {Background: Pyelonephritis is frequently linked to diabetes mellitus, serving as a common cause. Poor outcomes are associated with both emphysematous pyelonephritis (EPN) and non-emphysematous pyelonephritis (NEPN). This study was conducted to examine the clinical characteristics, microbiological profile, prognostic factors, and treatment outcomes of pyelonephritis specifically in diabetic patients.

Methods: Acute pyelonephritis is considered present when a patient experiences fever with chills, rigors, flank pain, nausea, and vomiting. A diagnosis is confirmed through USG and KUB studies showing an enlarged kidney, collection presence, and perinephric fat stranding. Urine samples are collected through midstream voiding, catheterization, or suprapubic needle aspiration. A positive urine culture indicates >105 CFU/ml of bacteria. Glycemic control is classified as good (HbA1c <7%), moderate (HbA1c 7-7.5%), or poor (HbA1c >7.5%). Emphysematous pyelonephritis classification is based on CT scan findings.

Results: In a study of 40 patients with acute pyelonephritis and type 2 diabetes, 80% had non-emphysematous pyelonephritis (NEPN) and 20% had emphysematous pyelonephritis (EPN). Over 75% in both groups experienced loin pain, a hallmark of acute pyelonephritis. Burning micturition affected 75% of EPN and 28.12% of NEPN patients. Less than 15% reported decreased urine output and vomiting in both groups. The NEPN group had significantly lower rates of burning micturition, possibly indicating a link to pyelonephritis severity. In EPN patients, 75% had normal CECT KUB findings, with 50% of abnormalities falling into Class 3A. Approximately 50% of both groups were treated without IV antibiotics, with conservative management dominating. Other interventions, including DJ stents, antifungals, hemodialysis, percutaneous nephrolithotomy, and ureteroscopy with stenting, were also employed.

Conclusion: Diagnosing emphysematous pyelonephritis (EPN) in diabetic patients with pyelonephritis symptoms, particularly with poorly controlled blood sugars, requires a high suspicion index and early imaging. Most affected individuals are aged 51-70 years. Cases of both non-emphysematous (NEPN) and EPN are predominantly associated with gram-negative bacteria. EPN patients in Class I-IIIA respond well to antibiotics or additional percutaneous drainage (PCN), while Class IIIB and Class IV cases may require nephrectomy.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Manorenj_2024,

title = {An interesting case of chronic isolated apathetic syndrome},

author = {Sandhya Manorenj and Rindha V. Rao and Reshma Sultana Shaik},

url = {https://sciencevolks.com/neurology/pdf/SVOA-NE-05-0124.pdf},

doi = {10.58624/SVOANE.2024.05.0124},

issn = {2753-9180},

year  = {2024},

date = {2024-01-10},

urldate = {2024-01-10},

journal = {SVOA Neurology},

volume = {5},

issue = {1},

pages = {37-40},

abstract = {An apathy syndrome is defined as a syndrome of primary motivational loss, that is, loss of motivation not attributable to emotional distress, intellectual impairment, or a diminished level of consciousness. The main anatomical correlate of apathy is the medial frontal lobe. Here we report a case of a 49-year-old male who presented with a history of lack of interest for the past 10 months without any other neurological symptoms. He was diagnosed with depression and was receiving treatment from multiple psychiatrists. In view of his persistent symptoms, he approached us and was evaluated. Examination showed anosmia with apathy that paved the way to the orbitofrontal location of the lesion. Psychiatric symptoms may be an unusual presentation of a space-occupying lesion of brain. Strong suspicion and imaging the brain is indicated in all cases to prevent the unnecessary use of psychiatric medicines and their complications. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Study to determine the common substances that caused deaths due to ingestion brought for autopsy in tertiary care hospital, Hyderabad, Telangana, India},

author = {Mohammed Abdul Mujeeb Siddiqui and Zahraa Mohammed Siddiqui and Azra Siddiqui and Katkuri Parvathi},

issn = {2393-915X},

year  = {2023},

date = {2023-12-31},

journal = {International Journal of Contemporary Medical Research},

volume = {10},

issue = {12},

pages = {L1-L5},

abstract = {Background: This study was conducted to know the common substances that caused deaths by ingestion, brought for autopsy to Osmania General Hospital, Hyderabad, Telangana State, India for a period three years. The cases of deaths due to poisoning were selected from the autopsies conducted and analyzed for the most commonly ingested substance.

Material and methods: The samples were collected for three consecutive years from January 2012 to December 2014.

The contents of the stomach were examined grossly and the samples were collected in three containers during autopsy

for each individual case. Portion of stomach and its contents, portions of liver, kidney, blood and body fluids were collected labeled and sent to the State Forensic Science Laboratory for analysis of unknown poison. The reports were analyzed. The data collected was arranged according to age, sex and substances detected.

Results: A total of 1196 cases of poisoning in three years were studied. Most of the deaths occurred, were due the ingestion of Organophosphates. It is the commonest insecticide used by farmers in fields. The common age group involved is between 21 years to 30 years ingesting organophosphates. In the deaths due to poisonings, men are predominantly involved compared to women.

Conclusion: In the study it was concluded that the ingestion of poisonous substance organophosphate is usually intentional and is used to commit suicide. In children it is mostly accidental. Poison can also be used as homicide to kill a

person.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jahangir_2023b,

title = {Comparison between misoprostol and dinoprostone in inducing labor},

author = {Juveria Jahangir and Anjum Kehkashan and Yusra Siddiqui and Summaiyah Yousuf and Syeda Shaheera},

url = {https://www.academicmed.org/Uploads/Volume5Issue6/286.%20[2115.%20JAMP_Anjum]%201388-1391.pdf},

doi = {10.47009/jamp.2023.5.6.286},

issn = {2687-5365},

year  = {2023},

date = {2023-12-31},

journal = {International Journal of Academic Medicine and Pharmacy},

volume = {5},

issue = {6},

pages = {1388-1391},

abstract = {Background: The objective of this study was to evaluate safety and efficacy of labour inducing prostaglandins E1 and E2. We compared the obstetrical outcomes of intra-vaginal misoprostol (PGE1) and intra-cervical dinoprostone gel (PGE2) in our study. Materials and Methods: The study included 100 full term pregnant women of 19 to 30 years age group, with a cephalic presentation of single live fetus. Fifty women were included in each group (study and control). Women in study group were given 50 micrograms of Misoprostol intravaginal, while the control group received 0.5 mg of intracervical dinoprostone gel each. Key parameters studied in both groups were average time taken for start of labour, induction time at birth, duration of delivery, oxytocin requirement and delivery method. Conclusion: In comparison to dinoprostone, our study found misoprostol to be a better option in inducing labour for both the mother and the fetus, due to its efficacy, safety, and affordability.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jahangir_2023,

title = {Study of route of delivery and perinatal outcome in oligohydramnios},

author = {Juveria Jahangir and Anjum Kehkeshan and Summaiyah Yousuf and Yusra Siddiqui and Rana Siddiqui},

url = {https://www.academicmed.org/Uploads/Volume5Issue6/285.%20[2114.%20JAMP_Anjum]%201385-1387.pdf},

doi = {10.47009/jamp.2023.5.6.285},

issn = {2687-5365},

year  = {2023},

date = {2023-12-31},

journal = {International Journal of Academic Medicine and Pharmacy},

volume = {5},

issue = {6},

pages = {1385-1387},

abstract = {Background: To study neonatal outcome and appropriate route of delivery in oligohydramnios of AFI < 5 cm in women at or beyond 34 weeks gestation. Methods: In this prospective case control study of 50 women (study group) with oligohydramnios of AFI < 5 cm at or beyond 34 weeks of gestation was compared with 50 women (control group) with normal AFI > 5 cm and less than 25 at or beyond 34 weeks matched for age, parity, gestational age. Women with PROM, gestational age < 34 weeks and greater than 40 weeks, congenital anomaly, PIH, multiple gestations were excluded from this study. This study was done in antenatal and intrapartum period for neonatal outcome and appropriate route of delivery. Results: In our study we found that oligohydramnios was associated with increased rate of non-reassuring fetal heart rate (25% Vs 6%), cesarean delivery (50% Vs 10%), low birth weight (60% Vs 25%), FGR (17% Vs 5%) and admission to NICU (15% Vs 5%). There was no neonatal death in the study. Conclusion: Pregnancies with isolated oligohydramnios (AFI <5 cm) at or beyond 34 weeks are associated with increased incidence of fetal distress (non-reassuring fetal heart rate), caesarean delivery, and low birth weight. Induction of labor was associated with increased rate of caesarean section due to fetal distress. No appropriate route of delivery can be recommended for isolated oligohydramnios.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Arifuddin_2023b,

title = {Effects of tuberculosis on genitourinary system},

author = {Mohammed Khaja Arifuddin and Syed Faiz Ahmed},

url = {https://www.jcdronline.org/paper.php?slug=effects-of-tuberculosis-on-genitourinary-system},

doi = {10.48047/jcdr.2023.14.12.265},

issn = {0975-3583},

year  = {2023},

date = {2023-12-31},

urldate = {2023-12-31},

journal = {Journal of Cardiovascular Disease Research},

volume = {14},

issue = {12},

pages = {2291-2299},

abstract = {Background: Genitourinary Tuberculosis (GUTB) is a common site of extrapulmonary tuberculosis. The disease involves the kidneys, ureters, bladder, or genital organs. Clinical symptoms develop 10 – 15 years after primary infection. Only one-quarter of patients with GUTB have a known history of TB and about half of these patients have chest radiography findings. The current study aimed to determine the effects of GUTB.

Methods: The included patients were successive cases with a diagnosis of genitourinary tuberculosis. A total of 62 cases were reported with the diagnosis of genitourinary tuberculosis. PCR for MTb was done in 37 cases. Radiological evaluation included chest X-ray, KUB in all cases, and intravenous urogram when serum creatinine was normal. FNAC was performed in cases with serosal masses. All patients received antitubercular drug therapy with 4 drugs (Rifampicin, Ethambutol, Isoniazid, and Pyrazinamide) for 2 months followed by 2 drugs (Rifampicin and Isoniazid) for 7 months.

Results: Positive AFB staining and positive MTb culture in urine were seen in 31.37% and 41.17% of cases, respectively, confirming the presence of Mycobacterium tuberculosis in some GUTB patients. Positive PCR for MTb in urine is present in 67.56% of cases (in a subset of 37 patients). MTb culture in pus is only observed in 4 out of 7 cases, suggesting its less frequent occurrence compared to other positive findings. Sterile urine is found in 78.95% of cases, and Radiological abnormalities (IVU/NCCT/MUCG) suggestive of GUTB was found in 46/57 (80.7%) cases. Bladder biopsy was positive in 12/25(48%) cases done. A comparison of urinary PCR with urine for AFB staining urine for MTb culture and bladder biopsy was done.

Conclusion: The urinary (PCR) stands out as the most sensitive indicator among all microbiological tests. When coupled with radiological abnormalities, it significantly expedites the diagnosis of genitourinary tuberculosis. Optimal treatment involves a combination of multidrug chemotherapy and judicious surgery, as necessary. It is highly advisable to make every effort to reconstruct the urinary tract due to the rewarding outcomes associated with this approach. However, in cases where tissue is infected and irreparably damaged, the most effective course of action is ablating the affected tissue.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Unnisa_2023,

title = {Effect of physical activity on glycated hemoglobin [HbA1c] in non-diabetic individuals},

author = {Arshiya Unnisa and Farah Bahmed and Farisa Khatoon and Mehnaaz Sameera Arifuddin and Nazia Uzma},

url = {https://journals.lww.com/jdyu/fulltext/2023/12030/effect_of_physical_activity_on_glycated_hemoglobin.15.aspx},

doi = {10.4103/jdrysruhs.jdrysruhs_24_22},

issn = {5555-6666},

year  = {2023},

date = {2023-12-27},

journal = {Journal of Dr. YSR University of Health Sciences},

volume = {12},

issue = {3},

pages = {285-290},

abstract = {Introduction: Physical inactivity is a rapidly evolving public health issue that contributes to a wide range of chronic diseases and health consequences, including obesity, diabetes, and cancer. In addition to improving a patient’s overall health, increased physical activity has been demonstrated to be beneficial in the management of chronic conditions. The purpose of this research is to discover if there is a link between physical activity intensity and HbA1c levels in non-diabetic adults and, if so, which type of physical activity has the most impact on glycemic control.

Material and Methods: There were 90 healthy non-diabetic individuals in the study. The International Physical Activity Questionnaire (IPAQ) score was calculated after each subject’s physical activity questionnaire was evaluated. Based on their IPAQ scores, the participants were split into three groups: low, moderate, and vigorous physical activity. A 3 mL blood sample was taken in a vacutainer to determine HbA1c levels. The data was produced in Microsoft Excel and analyzed using the statistical application SPSS 17.0.

Result: HbA1c values were statistically significant in the moderate-physical-activity group, while IPAQ showed a statistical difference between males and females in the vigorous-physical-activity group. In all three groups, IPAQ scores were significantly different but not in HbA1c levels. The HbA1c and IPAQ scores had a modest negative connection. The difference between males and females in our study was statistically insignificant. The body mass index (BMI) and HbA1c, as well as BMI and IPAQ, were found to have a positive linkage.

Conclusion: Physical activity, particularly moderate-to-vigorous activity, has a bigger influence on non-diabetic people’s glycemic regulation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nasirabadi_2023b,

title = {Charting a legacy of excellence and community empowerment:the odyssey of IMA Hyderabad city branch},

author = {Minhajzafar Nasirabadi and Srirang Abkari and Khan Mohammed Zeeshan Ali },

url = {https://www.tjima.org/journal/index.php/tjima/article/view/121/211},

doi = {10.52314/tjima.2023.v3i2.121},

year  = {2023},

date = {2023-12-22},

urldate = {2023-12-22},

journal = {Telangana Journal of IMA},

volume = {3},

issue = {2},

pages = {1-3},

abstract = {NA},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mirza_2023,

title = {A case report-astasia abasia treated with faradic stimulation},

author = {Samia Mirza and Khan Mohammad Zeeshan Ali and Saad Mohiuddin and Minhajzafar Nasirabadi},

url = {https://www.tjima.org/journal/index.php/tjima/article/view/135/229},

doi = {10.52314/tjima.2023.v3i2.135},

year  = {2023},

date = {2023-12-22},

urldate = {2023-12-22},

journal = {Telangana Journal of IMA},

volume = {3},

issue = {2},

pages = {55-57},

abstract = {Conversion disorder presents with a wide variety of symptoms, one of the rarest presentations being Astasia-Abasia; where the individual loses their ability to stand or walk normally without any apparent anatomic or physiologic abnormality. psychosocial stressors  have  been  observed  to  closely  precede  the  onset  of  symptoms.  Management  of  conversion  disorders  centres  around  psychoeducation and psychotherapy but the response is slow and varied. This case report describes one such case of a 13-year-old female with Astasia-Abasia who was successfully treated with Faradic stimulation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sultana_2023d,

title = {Morphometric study of human brain ventricles by magnetic resonance imaging in Indian population: a retrospective study},

author = {Zafar Sultana Abdul Saleem and Farah Bahmed and Syeda Sadia Sameera and Sravan Kumar Marupaka and Habib Khan Gulab Khan Pathan},

url = {https://journals.lww.com/jdyu/fulltext/2023/12020/morphometric_study_of_human_brain_ventricles_by.15.aspx},

doi = {10.4103/jdrntruhs.jdrntruhs_210_22},

issn = {5555-6666},

year  = {2023},

date = {2023-12-01},

urldate = {2023-12-01},

journal = {Journal of Dr. YSR University of Health Sciences},

volume = {12},

issue = {2},

pages = {171-177},

abstract = {Introduction: Ventricular parameters are used to study hydrocephalus, schizophrenia, tumors, trauma, Alzheimers disease, gender, aging and atrophy associated with many neurological diseases as stroke and dementia, to assess loss of brain parenchyma. Normal reference values of brain ventricles obtained by MRI are necessary to create baseline data for interpreting pathological changes, planning surgery and determining presence and progress of some neurological disorders. Materials and Method: This is a retrospective, cross sectional and non-interventional study. we have studied 100 brain MRI digital images. Following parameters have been studied frontal horn width [FHW], transverse internal diameter of skull[TIDS-F] at same level, frontal horn ratio[FHR], frontal horn length on both sides [FHLR & FHLL], total length of lateral ventricle on both sides [LVLR & LVLL], posterior horn width [PHW], transverse internal diameter of skull at same level [TIDS-P], fourth ventricle width [FVW] and fourth ventricle anteroposterior distance [FVAP]. SPSS. version. 21 was used for statistical analysis. Results: There were 54 females and 46 males between age 20 years to above 60 years. Frontal horn width, posterior horn width and total inner diameter of skull at frontal and posterior level has shown significant gender differences with P value as 0.0034,0.0004,0.00013 and 0.0004 respectively. Frontal horn ratio, total length of right and left lateral ventricles and total inner diameter of skull has shown significant increase with age. Conclusion: The normal reference values of ventricles obtained from MRI are necessary to form baseline data, for interpreting pathological changes and planning surgeries.volumetric measurements will provide more information than linear measurements.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Karan_2023b,

title = {The effect of durative computer usage on intraocular pressure},

author = {Siddharth Karan and Sheetal Baldava and Rahel Afzal and Farheen Fatima and Saira Begum},

url = {https://www.ijlbpr.com/uploadfiles/29vol12issue4pp162-165.20231019052727.pdf},

issn = {2250-3137},

year  = {2023},

date = {2023-10-31},

urldate = {2023-10-31},

journal = {International Journal of Life Sciences, Biotechnology and Pharma Research},

volume = {12},

issue = {4},

pages = {162-165},

abstract = {Aim: To investigate the changes in the Intraocular pressure (IOP) in adults on prolonged computer usage. Methods:31 adult subjects working with computers for prolonged hours had their Intraocular pressure checked with Schiotz tonometer. Measurements were taken initially on every individual before computer usage and then following 3 hours of computer usage. Results: There was significant rise in the Intraocular pressure (Mean Increase of Intraocular pressure is 1.23mm of Hg) in most of the myopic subjects after 3 hours of continuous usage of computer. Conclusions: Prolonged computer usage could induce transient Intraocular pressure elevation. Mostly Intraocular pressure elevation is seen in myopic subjects whereas emmetropic subjects showed little or no elevation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ali_2023b,

title = {Association between Candida albicans and COVID-19 in complete denture wearers: An observational study},

author = {Mohd. Osman Ali and Babashankar Alva and Suresh Nagaral and Rohit Patil and Mohammad Ullah Khan and Durgesh

A. Tiwari},

url = {https://www.cureus.com/articles/200623-association-between-candida-albicans-and-covid-19-in-complete-denture-wearers-an-observational-study#!/},

doi = {10.7759/cureus.47777},

issn = {2168-8184},

year  = {2023},

date = {2023-10-27},

journal = {Cureus},

volume = {15},

issue = {10},

pages = {e47777},

abstract = {Introduction: The phenomenon of coronavirus disease 2019 (COVID-19)-related candidiasis is gaining increased attention and acknowledgment as an integral component of the severe consequences of COVID-19. The aim of the

present study was to assess the association between Candida albicans and COVID-19 in complete denture wearers.

Materials and methods: An observational study was conducted on 45 complete denture wearers, who were divided into three groups as follows: Group 1, 15 subjects with mild to moderate COVID-19 infection; Group 2, 15 subjects with severe COVID-19 infection; and Group 3, 15 subjects without COVID-19 infection. Mean colony forming units (CFU) were observed on agar plates containing Sabouraud dextrose in the salivary samples of the participants. Analysis of variance, followed by post-hoc analysis by Tukey’s test, was used to compare CFU between the groups. Pearson’s correlation coefficient was used to study the correlation between variables.

Results: The highest average colony-forming units of Candida albicans were observed in Group 2, followed by Group

1, compared to the control group, and a significant (p<0.001) difference was found. A weak positive correlation was found between the age of the patients and the duration of denture usage, as well as between age and the counts of Candida albicans in Groups 1 and 3. This correlation was more pronounced in Group 3. A strong positive correlation was observed in all groups between the Candida albicans count and the duration of denture usage by the patients.

Conclusion: The association between Candida albicans and denture wear was compounded by the presence of COVID-19. Consequently, the timely identification of Candida albicans infection in patients with COVID-19 is

important to establish more efficacious approaches for antifungal treatment and prophylactic interventions.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Quadri_2023,

title = {A study of factors affecting and outcomes in difficult total knee arthroplasty},

author = {Saadullah Khan Quadri and Mohammed Akram and Mohammed Siddique Mohiuddin and Mohammed Abdul Bari and Mohammed Abid Hussain and Mohammed Firdouse and Asapanna Naga Sai Venkata Yeshwanth},

url = {https://healthcare-bulletin.co.uk/article/volume-13-issue-4-pages306-312-ra/},

doi = {10.5083/ejcm},

issn = {2042-4884},

year  = {2023},

date = {2023-10-20},

urldate = {2023-10-20},

journal = {European Journal of Cardiovascular Medicine},

volume = {13},

issue = {4},

pages = {306-312},

abstract = {Background: This prospective observational study was undertaken to look into the factors that affect the outcome of total knee arthroplasty and the short-term results of total knee replacements in complex knee pathologies. Methods: This prospective observational study was conducted between 2021 and 2023 at Owaisi Hospital and Research Centre, Hyderabad. A consecutive series of 12 total knee arthroplasties was performed on 12 patients at our institute using PFC Sigma endoprosthesis. The patients were assessed clinically and radiologically using the INSALL scoring system.  Results: The average pre-operative range of motion (flexion) was 45˚, with a highest of 120˚ and a lowest of 0˚. The average post-operative flexion was 102˚, with a highest of 130˚ and a lowest of 90˚. The average extension lag preoperatively was 18˚, and the average postoperative extension lag was less than 10˚. The average pre-operative knee score was 64.84, with the highest score of 91 and the lowest score of 40. The majority of the patients had a score in the range of 51–100. The average post-operative knee score was 136.84, with the highest score of 160 and the lowest score of 120. A majority of the patients had an improvement in score in the range of 101–150. At 6 months, follow-up relief was excellent in most patients; only 10 patients had anterior knee pain, and all the patients were able to walk more than 50 blocks post-operatively without any walking aid. Conclusion: Determining the factors resulting in a difficult knee helps in formulating an appropriate surgical approach, which results in a better functional outcome following total knee arthroplasty.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}